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Chiranjit Ghosh, Ph.D.

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University of Waterloo, CanadaPostdoctorate02/2020Analytcial Chemistry
University of Calcutta, KolkataPhD08/2018Chemistry
Young Investigator Award
Best Oral Paper Presentation
Best Paper Award
International Travel Grant
International Travel Grant
IFCC-TFYS Young Scientists Award
Young Scientist International Travel Grant
SIGMA-ALDRICH Excellent Poster Award
Student Travel Award
One of the best six research papers award
2nd best prize for oral presentation award
Young Scientist Travel Grant
One of the best poster prize
Best Innovation Research Award
Best Oral Presentation Award
Best Poster Presentation Prize
Qualified Graduate Aptitude Test in Engineering (GATE), 2013
University Grant Commission-Basic Scientific Research Fellowship in Science and for Meritorious Stud

It is my great pleasure to welcome you in my Harvard Catalyst profile. I obtained my Ph.D. in chemistry from the Satyendra Nath Bose National Centre for Basic Sciences, India (An autonomous Research Institute under Government of India) in 2018, under the supervision of Dr. Manik Pradhan. My thesis works were focused to develop the non-invasive method from human breath analysis to screen biomedical diseases like diabetes, Helicobacter pylori infection etc. I have 16 publications in international journals including Nature Publishing group. I have filed 3 patents (Indian) during my PhD. In 2108, I joined as a postdoctorate researcher in the analytical chemistry of Professor Janusz Pawliszyn's Research Group at the University of Waterloo, Canada. During my stay in Pawliszyn's group, my research works mainly focused on the development of breath analysis method exploiting solid phase micro-extraction (SPME) and needle trap (NT) technology for real-time analysis of volatile organic compounds (VOCs) in breath for evaluation of human health and a variety of disease states. After spending almost 2yrs at the University of Waterloo, I joined as a postdoctoral research fellow at Harvard Medical School/ BWH in 2020. Here, I am working on the animal model to identify novel volatile biomarkers of specific fungal and bacterial infections and examine the dynamics of these metabolites with antibiotic or antifungal therapy.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ghosh C, Leon A, Koshy S, Aloum O, Al-Jabawi Y, Ismail N, Weiss ZF, Koo S. Breath-Based Diagnosis of Infectious Diseases: A Review of the Current Landscape. Clin Lab Med. 2021 Jun; 41(2):185-202. PMID: 34020759.
    Citations:    Fields:    
  2. Singh, Varoon; Ghosh, Chiranjit; Kaur, Avneet; Pawliszyn, Janusz (2020): Polyvinylidene Difluoride: A Universal Binder for Preparation of Solid Phase Microextraction Devices. ChemRxiv. . Polyvinylidene Difluoride: A Universal Binder for Preparation of Solid Phase Microextraction Devices. 2020. View Publication.
  3. Chiranjit Ghosh, Varoon Singh, Jonathan Grandy, Janusz Pawliszyn. Development and validation of a headspace needle-trap method for rapid quantitative estimation of butylated hydroxytoluene from cosmetics by hand-portable GC-MS. RSC Advances. 2020; 10:6671. View Publication.
  4. Chiranjit Ghosh, Manik Pradhan. System and kit for monitoring blood glucose profile based on breath analysis.INDIAN PATENT fILE NO 201631003758. 2020.
  5. Ghosh C, Singh V, Grandy J, Pawliszyn J. Recent advances in breath analysis to track human health by new enrichment technologies. J Sep Sci. 2020 Jan; 43(1):226-240. PMID: 31826324.
    Citations: 1     Fields:    Translation:Humans
  6. Sanchi Maithani, Abhijit Maity, Mithun Pal, Sayoni Bhattacharya, Gourab Dutta Banik, Chiranjit Ghosh, Sujit Chaudhuri, Manik Pradhan. Isotopic evidences of the preferential coordination between 12CO2 and urease enzyme. Chemical Physics. 2019; 520:21. View Publication.
  7. Mandal S, Mukhopadhyay P, Ghosh C, Pal M, Banik GD, Chatterjee T, Ghosh S, Pradhan M. Isotope-specific breath analysis to track the end-stage renal disease during hemodialysis. J Breath Res. 2018 05 29; 12(3):036019. PMID: 29560929.
    Citations:    Fields:    Translation:Humans
  8. Som S, Dutta Banik G, Maity A, Ghosh C, Chaudhuri S, Pradhan M. Non-invasive diagnosis of type 2 diabetes in Helicobacter pylori infected patients using isotope-specific infrared absorption measurements. Isotopes Environ Health Stud. 2018 Aug; 54(4):435-445. PMID: 29688034.
    Citations:    Fields:    Translation:HumansCells
  9. Ghosh C, Mandal S, Pal M, Pradhan M. New Strategy for in Vitro Determination of Carbonic Anhydrase Activity from Analysis of Oxygen-18 Isotopes of CO2. Anal Chem. 2018 01 16; 90(2):1384-1387. PMID: 29244947.
    Citations:    Fields:    Translation:HumansCells
  10. Chiranjit Ghosh, Santanu Mondal, Manik Pradhan. A System for monitoring hemodialysis efficacy of a subject. INDIAN PATENT FILE NO 201731042502. 2017.
  11. Ghosh C, Mandal S, Pal M, Mukhopadhyay P, Ghosh S, Pradhan M. 13C isotopic abundances in natural nutrients: a newly formulated test meal for non-invasive diagnosis of type 2 diabetes. J Breath Res. 2017 06 01; 11(2):026005. PMID: 28569242.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  12. Chiranjit Ghosh, Manik Pradhan, Debashis Patra, Tapas Ghosh. Dioxo vanadium (V) complex as carbonic anhydrase inhibitor. INDIAN PATENT FILE NO. 201631038296. 2016.
  13. Ghosh C, Mandal S, Banik GD, Maity A, Mukhopadhyay P, Ghosh S, Pradhan M. Targeting erythrocyte carbonic anhydrase and 18O-isotope of breath CO2 for sorting out type 1 and type 2 diabetes. Sci Rep. 2016 10 21; 6:35836. PMID: 27767104.
    Citations: 1     Fields:    Translation:HumansCells
  14. Sankar Das, Chiranjit Ghosh, Subhra Jana. Moisture induced isotopic carbon dioxide trapping from ambient air. Journal of Materials Chemistry A. 2016. View Publication.
  15. Ghosh C, Mukhopadhyay P, Ghosh S, Pradhan M. Insulin sensitivity index (ISI0, 120) potentially linked to carbon isotopes of breath CO2 for pre-diabetes and type 2 diabetes. Sci Rep. 2015 Jul 07; 5:11959. PMID: 26148706.
    Citations: 1     Fields:    Translation:Humans
  16. Som S, De A, Banik GD, Maity A, Ghosh C, Pal M, Daschakraborty SB, Chaudhuri S, Jana S, Pradhan M. Mechanisms linking metabolism of Helicobacter pylori to (18)O and (13)C-isotopes of human breath CO2. Sci Rep. 2015 Jun 03; 5:10936. PMID: 26039789.
    Citations:    Fields:    Translation:HumansCells
  17. Jana S, Das S, Ghosh C, Maity A, Pradhan M. Halloysite nanotubes capturing isotope selective atmospheric CO2. Sci Rep. 2015 Mar 04; 5:8711. PMID: 25736700.
    Citations: 2     Fields:    
  18. Ghosh C, Banik GD, Maity A, Som S, Chakraborty A, Selvan C, Ghosh S, Chowdhury S, Pradhan M. Oxygen-18 isotope of breath CO2 linking to erythrocytes carbonic anhydrase activity: a biomarker for pre-diabetes and type 2 diabetes. Sci Rep. 2015 Jan 30; 5:8137. PMID: 25633556.
    Citations: 4     Fields:    Translation:HumansCells
  19. Ghosh C, Maity A, Banik GD, Som S, Chakraborty A, Selvan C, Ghosh S, Ghosh B, Chowdhury S, Pradhan M. Non-invasive 13C-glucose breath test using residual gas analyzer-mass spectrometry: a novel tool for screening individuals with pre-diabetes and type 2 diabetes. J Breath Res. 2014 Sep; 8(3):036001. PMID: 24946152.
    Citations: 4     Fields:    Translation:Humans
  20. Som S, Maity A, Banik GD, Ghosh C, Chaudhuri S, Daschakraborty SB, Ghosh S, Pradhan M. Excretion kinetics of 13C-urea breath test: influences of endogenous CO2 production and dose recovery on the diagnostic accuracy of Helicobacter pylori infection. Anal Bioanal Chem. 2014 Sep; 406(22):5405-12. PMID: 24939135.
    Citations: 2     Fields:    Translation:HumansCells
  21. Maity A, Banik GD, Ghosh C, Som S, Chaudhuri S, Daschakraborty SB, Ghosh S, Ghosh B, Raychaudhuri AK, Pradhan M. Residual gas analyzer mass spectrometry for human breath analysis: a new tool for the non-invasive diagnosis of Helicobacter pylori infection. J Breath Res. 2014 Mar; 8(1):016005. PMID: 24566134.
    Citations: 6     Fields:    Translation:HumansCells
  22. Abhijit Maity, Suman Som, Chiranjit Ghosh et al. Oxygen-18 stable isotope of exhaled breath CO2 as a non-invasive marker of Helicobacter pylori infection. Journal of Analytical Atomic Spectrometry. 2014; 29:2251. View Publication.
  23. Gourab Dutta Banik, Abhijit Maity, Suman Som, Chiranjit Ghosh et al. Diagnosis of small intestinal bacterial overgrowth in irritable bowel syndrome patients using high-precision stable 13CO2/12CO2 isotope ratios in exhaled breath. Journal of Analytical Atomic Spectrometry. 2014; 29:1918. View Publication.
  24. Manik Pradhan, Gourab Dutta Banik, Abhijit Maity, Chiranjit Ghosh, Suman Som:. DAE-BRNS National Laser Symposium (NLS-22) KIRAN. Applications of cavity ring-down laser spectroscopy to biomedical disease detection using exhaled breath analysis,. 2013; 24. View Publication.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.