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Laurie E. Cohen, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R03DK056157 (COHEN, LAURIE E) Sep 1, 1999 - Aug 31, 2002
    NIH/NIDDK
    MOLECULAR BASIS OF HYPOPITUITARISM IN MAN
    Role: Principal Investigator
  2. K11DK002329 (COHEN, LAURIE E) Sep 1, 1995 - Aug 31, 2002
    NIH/NIDDK
    MOLECULAR BASIS OF HYPOPITUITARISM IN MAN
    Role: Principal Investigator
  3. F32DK008965 (COHEN, LAURIE E) Jan 5, 1994
    NIH/NIDDK
    MOLECULAR BASIS OF PITUITARY HORMONE DEFICIENCIES
    Role: Principal Investigator
  4. M01RR002172 (MANDELL, JAMES WILLIAM) Jan 1, 1983 - Mar 31, 2009
    NIH/NCRR
    General Clinical Research Center
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tamhane S, Sfeir JG, Kittah NEN, Jasim S, Chemaitilly W, Cohen LE, Murad MH. GH Therapy in Childhood Cancer Survivors: A Systematic Review and Meta-Analysis. J Clin Endocrinol Metab. 2018 08 01; 103(8):2794-2801. PMID: 29982555.
    Citations:    Fields:    
  2. Sklar CA, Antal Z, Chemaitilly W, Cohen LE, Follin C, Meacham LR, Murad MH. Hypothalamic-Pituitary and Growth Disorders in Survivors of Childhood Cancer: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2018 08 01; 103(8):2761-2784. PMID: 29982476.
    Citations:    Fields:    
  3. Sfeir JG, Kittah NEN, Tamhane SU, Jasim S, Chemaitilly W, Cohen LE, Murad MH. Diagnosis of GH Deficiency as a Late Effect of Radiotherapy in Survivors of Childhood Cancers. J Clin Endocrinol Metab. 2018 08 01; 103(8):2785-2793. PMID: 29982753.
    Citations:    Fields:    
  4. Chemaitilly W, Cohen LE, Mostoufi-Moab S, Patterson BC, Simmons JH, Meacham LR, van Santen HM, Sklar CA. Endocrine Late Effects in Childhood Cancer Survivors. J Clin Oncol. 2018 Jul 20; 36(21):2153-2159. PMID: 29874130.
    Citations:    Fields:    
  5. Chemaitilly W, Cohen LE. DIAGNOSIS OF ENDOCRINE DISEASE: Endocrine late-effects of childhood cancer and its treatments. Eur J Endocrinol. 2017 04; 176(4):R183-R203. PMID: 28153840.
    Citations: 3     Fields:    Translation:Humans
  6. Nahata L, Ziniel SI, Garvey KC, Yu RN, Cohen LE. Fertility and sexual function: a gap in training in pediatric endocrinology. J Pediatr Endocrinol Metab. 2017 Jan 01; 30(1):3-10. PMID: 27658131.
    Citations: 2     Fields:    Translation:Humans
  7. Grimberg A, DiVall SA, Polychronakos C, Allen DB, Cohen LE, Quintos JB, Rossi WC, Feudtner C, Murad MH. Guidelines for Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents: Growth Hormone Deficiency, Idiopathic Short Stature, and Primary Insulin-Like Growth Factor-I Deficiency. Horm Res Paediatr. 2016; 86(6):361-397. PMID: 27884013.
    Citations: 15     Fields:    Translation:Humans
  8. Cohen LE. Update on childhood craniopharyngiomas. Curr Opin Endocrinol Diabetes Obes. 2016 08; 23(4):339-44. PMID: 27258775.
    Citations:    Fields:    Translation:Humans
  9. Nahata L, Yu RN, Cohen LE. Klinefelter syndrome: fertility considerations and gaps in knowledge. Transl Pediatr. 2016 Jul; 5(3):183-184. PMID: 27709101.
    Citations:    
  10. Christiansen JS, Backeljauw PF, Bidlingmaier M, Biller BM, Boguszewski MC, Casanueva FF, Chanson P, Chatelain P, Choong CS, Clemmons DR, Cohen LE, Cohen P, Frystyk J, Grimberg A, Hasegawa Y, Haymond MW, Ho K, Hoffman AR, Holly JM, Horikawa R, Höybye C, Jorgensen JO, Johannsson G, Juul A, Katznelson L, Kopchick JJ, Lee KO, Lee KW, Luo X, Melmed S, Miller BS, Misra M, Popovic V, Rosenfeld RG, Ross J, Ross RJ, Saenger P, Strasburger CJ, Thorner MO, Werner H, Yuen K. Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations. Eur J Endocrinol. 2016 Jun; 174(6):C1-8. PMID: 27009113.
    Citations: 6     Fields:    Translation:Humans
  11. Nahata L, Yu RN, Paltiel HJ, Chow JS, Logvinenko T, Rosoklija I, Cohen LE. Sperm Retrieval in Adolescents and Young Adults with Klinefelter Syndrome: A Prospective, Pilot Study. J Pediatr. 2016 Mar; 170:260-5.e1-2. PMID: 26746120.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  12. Nahata L, Yu RN, Bhasin S, Cohen LE. Management of testosterone therapy in adolescents and young men with hypogonadism: are we following adult clinical practice guidelines? J Pediatr Endocrinol Metab. 2015 May; 28(5-6):635-40. PMID: 25324443.
    Citations: 1     Fields:    Translation:Humans
  13. Cohen LE. Idiopathic short stature: a clinical review. JAMA. 2014 May 07; 311(17):1787-96. PMID: 24794372.
    Citations: 5     Fields:    Translation:Humans
  14. Cohen LE. JAMA patient page. Short stature. JAMA. 2014 May 07; 311(17):1822. PMID: 24794385.
    Citations:    Fields:    Translation:Humans
  15. Lee JJ, Mitchell PD, Hood HC, Grand RJ, Cohen LE. Potential role of IGF-1 z score to predict permanent linear growth impairment in children with IBD. J Pediatr Gastroenterol Nutr. 2014 Apr; 58(4):472-6. PMID: 24663033.
    Citations: 1     Fields:    Translation:Humans
  16. Nahata L, Rosoklija I, Yu RN, Cohen LE. Klinefelter syndrome: are we missing opportunities for early detection? Clin Pediatr (Phila). 2013 Oct; 52(10):936-41. PMID: 23836810.
    Citations: 3     Fields:    Translation:Humans
  17. Robison NJ, Prabhu SP, Sun P, Chi SN, Kieran MW, Manley PE, Cohen LE, Goumnerova L, Smith ER, Scott RM, London WB, Ullrich NJ. Predictors of neoplastic disease in children with isolated pituitary stalk thickening. Pediatr Blood Cancer. 2013 Oct; 60(10):1630-5. PMID: 23670879.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  18. Wassner AJ, Cohen LE, Hechter E, Dauber A. Isolated central hypothyroidism in young siblings as a manifestation of PROP1 deficiency: clinical impact of whole exome sequencing. Horm Res Paediatr. 2013; 79(6):379-86. PMID: 23652424.
    Citations: 2     Fields:    Translation:Humans
  19. Cohen LE. GLI2 mutations as a cause of hypopituitarism. Pediatr Endocrinol Rev. 2012 Aug; 9(4):706-9. PMID: 23304807.
    Citations: 1     Fields:    Translation:HumansCells
  20. Kenney LB, Cohen LE, Shnorhavorian M, Metzger ML, Lockart B, Hijiya N, Duffey-Lind E, Constine L, Green D, Meacham L. Male reproductive health after childhood, adolescent, and young adult cancers: a report from the Children's Oncology Group. J Clin Oncol. 2012 Sep 20; 30(27):3408-16. PMID: 22649147.
    Citations: 23     Fields:    Translation:Humans
  21. Nahata L, Cohen LE, Lehmann LE, Yu RN. Semen analysis in adolescent cancer patients prior to bone marrow transplantation: when is it too late for fertility preservation? Pediatr Blood Cancer. 2013 Jan; 60(1):129-32. PMID: 22556027.
    Citations: 3     Fields:    Translation:Humans
  22. Nahata L, Cohen LE, Yu RN. Barriers to fertility preservation in male adolescents with cancer: it's time for a multidisciplinary approach that includes urologists. Urology. 2012 Jun; 79(6):1206-9. PMID: 22542423.
    Citations: 6     Fields:    Translation:Humans
  23. Manley PE, McKendrick K, McGillicudy M, Chi SN, Kieran MW, Cohen LE, Kothare S, Michael Scott R, Goumnerova LC, Sun P, London W, Marcus KJ, Pomeroy SL, Ullrich NJ. Sleep dysfunction in long term survivors of craniopharyngioma. J Neurooncol. 2012 Jul; 108(3):543-9. PMID: 22528788.
    Citations: 6     Fields:    Translation:Humans
  24. Cohen LE. Genetic disorders of the pituitary. Curr Opin Endocrinol Diabetes Obes. 2012 Feb; 19(1):33-9. PMID: 22157402.
    Citations: 5     Fields:    Translation:Humans
  25. Hood HC, Cohen LE, Lee JJ. Late adolescent linear growth pattern in pediatric-onset inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2011 Sep; 53(3):246-9. PMID: 21865969.
    Citations: 4     Fields:    Translation:Humans
  26. Cohen LE, Gordon JH, Popovsky EY, Sainath NN, Feldman HA, Kieran MW, Gordon CM. Bone density in post-pubertal adolescent survivors of childhood brain tumors. Pediatr Blood Cancer. 2012 Jun; 58(6):959-63. PMID: 22431246.
    Citations: 2     Fields:    Translation:Humans
  27. Winkfield KM, Tsai HK, Yao X, Larson E, Neuberg D, Pomeroy SL, Ullrich NJ, Cohen LE, Kieran MW, Scott RM, Goumnerova LC, Marcus KJ. Long-term clinical outcomes following treatment of childhood craniopharyngioma. Pediatr Blood Cancer. 2011 Jul 01; 56(7):1120-6. PMID: 21488157.
    Citations: 6     Fields:    Translation:Humans
  28. Topor LS, Feldman HA, Bauchner H, Cohen LE. Variation in methods of predicting adult height for children with idiopathic short stature. Pediatrics. 2010 Nov; 126(5):938-44. PMID: 20974789.
    Citations: 5     Fields:    Translation:Humans
  29. Masoud MI, Masoud I, Kent RL, Gowharji N, Hassan AH, Cohen LE. Relationship between blood-spot insulin-like growth factor 1 levels and hand-wrist assessment of skeletal maturity. Am J Orthod Dentofacial Orthop. 2009 Jul; 136(1):59-64. PMID: 19577149.
    Citations: 4     Fields:    Translation:Humans
  30. Fofanova-Gambetti OV, Hwa V, Kirsch S, Pihoker C, Chiu HK, Högler W, Cohen LE, Jacobsen C, Derr MA, Rosenfeld RG. Three novel IGFALS gene mutations resulting in total ALS and severe circulating IGF-I/IGFBP-3 deficiency in children of different ethnic origins. Horm Res. 2009; 71(2):100-10. PMID: 19129715.
    Citations: 5     Fields:    Translation:Humans
  31. Masoud M, Masoud I, Kent RL, Gowharji N, Cohen LE. Assessing skeletal maturity by using blood spot insulin-like growth factor I (IGF-I) testing. Am J Orthod Dentofacial Orthop. 2008 Aug; 134(2):209-16. PMID: 18675202.
    Citations: 9     Fields:    Translation:Humans
  32. Jacobsen CM, Cohen LE. Short stature in a phenotypic male caused by mixed gonadal dysgenesis. Nat Clin Pract Endocrinol Metab. 2008 Sep; 4(9):524-8. PMID: 18648333.
    Citations:    Fields:    Translation:Humans
  33. Cohen LE. Cancer treatment and the ovary: the effects of chemotherapy and radiation. Ann N Y Acad Sci. 2008; 1135:123-5. PMID: 18574217.
    Citations: 6     Fields:    Translation:Humans
  34. Dorsey MJ, Cohen LE, Phipatanakul W, Denufrio D, Schneider LC. Assessment of adrenal suppression in children with asthma treated with inhaled corticosteroids: use of dehydroepiandrosterone sulfate as a screening test. Ann Allergy Asthma Immunol. 2006 Aug; 97(2):182-6. PMID: 16937748.
    Citations: 3     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  35. Cohen LE. Endocrine late effects of cancer treatment. Endocrinol Metab Clin North Am. 2005 Sep; 34(3):769-89, xi. PMID: 16085170.
    Citations: 10     Fields:    Translation:HumansPHPublic Health
  36. Fleischman A, Brue C, Poussaint TY, Kieran M, Pomeroy SL, Goumnerova L, Scott RM, Cohen LE. Diencephalic syndrome: a cause of failure to thrive and a model of partial growth hormone resistance. Pediatrics. 2005 Jun; 115(6):e742-8. PMID: 15930202.
    Citations: 9     Fields:    Translation:Humans
  37. Cohen LE. . Endocrine Sequelae of Therapy for Cancer in Children. Endo Metab Clin NA. 2005.
  38. Cohen LE. . “Endocrine Sequelae in Cancer Survivors”. Syllabus for A Current Review of Endocrinology, Serono Symposium, San Diego, CA. 2005.
  39. Cohen RN, Cohen LE, Botero D, Yu C, Sagar A, Jurkiewicz M, Radovick S. Enhanced repression by HESX1 as a cause of hypopituitarism and septooptic dysplasia. J Clin Endocrinol Metab. 2003 Oct; 88(10):4832-9. PMID: 14557462.
    Citations: 23     Fields:    Translation:HumansCells
  40. Dalton VK, Rue M, Silverman LB, Gelber RD, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin M, Tarbell NJ, Sallan SE, Cohen LE. Height and weight in children treated for acute lymphoblastic leukemia: relationship to CNS treatment. J Clin Oncol. 2003 Aug 01; 21(15):2953-60. PMID: 12885815.
    Citations: 27     Fields:    Translation:Humans
  41. Hashimoto Y, Cisternino M, Cohen LE. A novel nonsense mutation in the Pit-1 gene: evidence for a gene dosage effect. J Clin Endocrinol Metab. 2003 Mar; 88(3):1241-7. PMID: 12629113.
    Citations: 4     Fields:    Translation:HumansCells
  42. Cohen LE. Endocrine late effects of cancer treatment. Curr Opin Pediatr. 2003 Feb; 15(1):3-9. PMID: 12544265.
    Citations: 4     Fields:    Translation:Humans
  43. Botero D, Evliyaoglu O, Cohen LE. . Hypopituitarism . Clinical Management of Pediatric Endocrine Disorders.Radovick S and MacGillivray M, editors. 2003; 3-36.
  44. Cohen LE. . “Molecular Basis of Hypopituitarism”. Syllabus for A Current Review of Endocrinology, Serono Symposium, Seattle, WA. 2003.
  45. Cohen LE, Radovick S. Other transcription factors and hypopituitarism. Rev Endocr Metab Disord. 2002 Dec; 3(4):301-11. PMID: 12424432.
    Citations: 1     Fields:    Translation:Humans
  46. Cohen LE, Radovick S. Molecular basis of combined pituitary hormone deficiencies. Endocr Rev. 2002 Aug; 23(4):431-42. PMID: 12202459.
    Citations: 31     Fields:    Translation:HumansAnimals
  47. Narayan M, Cohen L, Goumnerova L. Eating Dysfunction Following Endoscopic Third Ventriculostomy. American Association of Neurological Surgery. 2002.
  48. Carpentieri SC, Waber DP, Scott RM, Goumnerova LC, Kieran MW, Cohen LE, Kim F, Billett AL, Tarbell NJ, Pomeroy SL. Memory deficits among children with craniopharyngiomas. Neurosurgery. 2001 Nov; 49(5):1053-7; discussion 1057-8. PMID: 11846897.
    Citations: 20     Fields:    Translation:Humans
  49. Cohen LE, Knight JR. Constitutional Short Stature: Timmy and the “Big Kids”. In: Knight JR and Emans SJ, editors. Bright Futures Case Studies for Primary Care Clinicians, A Guide to the Case Teaching Method; and Growth in Children and Adolescents. U.S. Department of Health and Human Services, Health Resources and Services Administration, Maternal and Child Health Bureau. 2001.
  50. Cohen LE. Understanding Growth: Normal vs. Abnormal Patterns. In: Knight JR and Emans SJ, editors. Bright Futures Case Studies for Primary Care Clinicians, A Guide to the Case Teaching Method; and Growth in Children and Adolescents. U.S. Department of Health and Human Services, Health Resources and Services Administration, Maternal and Child Health Bureau. 2001.
  51. Samuels RC, Cohen LE. . Understanding Growth Patterns. Contemporary Pediatrics. 2001; 18:94-122.
  52. Hashimoto K, Zanger K, Hollenberg AN, Cohen LE, Radovick S, Wondisford FE. cAMP response element-binding protein-binding protein mediates thyrotropin-releasing hormone signaling on thyrotropin subunit genes. J Biol Chem. 2000 Oct 27; 275(43):33365-72. PMID: 10931853.
    Citations: 14     Fields:    Translation:HumansCells
  53. Cohen LE. Genetic regulation of the embryology of the pituitary gland and somatotrophs. Endocrine. 2000 Apr; 12(2):99-106. PMID: 10905370.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  54. Cohen LE, Hashimoto Y, Zanger K, Wondisford F, Radovick S. CREB-independent regulation by CBP is a novel mechanism of human growth hormone gene expression. J Clin Invest. 1999 Oct; 104(8):1123-30. PMID: 10525051.
    Citations: 12     Fields:    Translation:HumansCells
  55. Cohen LE, Zanger K, Brue T, Wondisford FE, Radovick S. Defective retinoic acid regulation of the Pit-1 gene enhancer: a novel mechanism of combined pituitary hormone deficiency. Mol Endocrinol. 1999 Mar; 13(3):476-84. PMID: 10077004.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  56. Zanger K, Cohen LE, Hashimoto K, Radovick S, Wondisford FE. A novel mechanism for cyclic adenosine 3',5'-monophosphate regulation of gene expression by CREB-binding protein. Mol Endocrinol. 1999 Feb; 13(2):268-75. PMID: 9973256.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  57. Radovick S, Cohen LE. . “Anterior Pituitary Hormone Deficiencies”. Syllabus for A Current Review of Endocrinology, Serono Symposium, New Orleans, LA. 1999.
  58. Cohen LE, Radovick S, Wondisford FE. . Transcription Factors and Hypopituitarism. TEM. 1999; 10:326-332.
  59. Hamilton J, Chitayat D, Blaser S, Cohen LE, Phillips III JA, Daneman D. . Familial Growth Hormone Deficiency Associated with MRI Abnormalities. Amer J Human Genetics. 1998; 80:128-132.
  60. Radovick S, Cohen LE, Wondisford FE. The molecular basis of hypopituitarism. Horm Res. 1998; 49 Suppl 1:30-6. PMID: 9554467.
    Citations: 2     Fields:    Translation:Humans
  61. Medlock MD, Madsen JR, Barnes PD, Anthony DS, Cohen LE, Scott RM. Optic chiasm astrocytomas of childhood. 1. Long-term follow-up. Pediatr Neurosurg. 1997 Sep; 27(3):121-8. PMID: 9548522.
    Citations: 1     Fields:    Translation:Humans
  62. Cohen LE, Wondisford FE, Radovick S. . Molecular Aspects of Hormone Deficiency Caused by Pit-1 Gene Mutations. Advances in Molecular and Cellular Endocrinology. LeRoith D, editor. 1997; 1:31-50.
  63. Poussaint TY, Barnes PD, Nichols K, Anthony D, Cohen LE, Tarbell NJ, Goumnerova L. Diencephalic syndrome: Clinical Features and Imaging Findings. Amer J of Neuroradiology. 1997; 18:1499-1505.
  64. Cohen LE, Wondisford FE, Radovick S. . Role of Pit-1 on the Expression of Growth Hormone, Prolactin, and Thyrotropin. Endo Metab Clin NA. 1996; 25:523-540.
  65. Cohen LE. Controversies in Clinical and Surgical Endocrinology. Short Stature. In: Herrera MF, Lerman I, editors. 1996.
  66. Cohen LE, Wondisford FE, Salvatoni A, Maghnie M, Brucker-Davis F, Weintraub BD, Radovick S. A "hot spot" in the Pit-1 gene responsible for combined pituitary hormone deficiency: clinical and molecular correlates. J Clin Endocrinol Metab. 1995 Feb; 80(2):679-84. PMID: 7852536.
    Citations: 14     Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.