Harvard Catalyst Profiles

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Marc Wehrli, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Leick MB, Silva H, Scarfò I, Larson R, Choi BD, Bouffard AA, Gallagher K, Schmidts A, Bailey SR, Kann MC, Jan M, Wehrli M, Grauwet K, Horick N, Frigault MJ, Maus MV. Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia. Cancer Cell. 2022 05 09; 40(5):494-508.e5. PMID: 35452603; PMCID: PMC9107929.
    Citations: 1     Fields:    Translation:HumansCells
  2. Bailey SR, Vatsa S, Larson RC, Bouffard AA, Scarfò I, Kann MC, Berger TR, Leick MB, Wehrli M, Schmidts A, Silva H, Lindell KA, Demato A, Gallagher KME, Frigault MJ, Maus MV. Blockade or Deletion of IFN? Reduces Macrophage Activation without Compromising CAR T-cell Function in Hematologic Malignancies. Blood Cancer Discov. 2022 03 01; 3(2):136-153. PMID: 35015685; PMCID: PMC9414118.
    Citations: 5     Fields:    Translation:HumansCells
  3. Wehrli M, Gallagher K, Chen YB, Leick MB, McAfee SL, El-Jawahri AR, DeFilipp Z, Horick N, O'Donnell P, Spitzer T, Dey B, Cook D, Trailor M, Lindell K, Maus MV, Frigault MJ. Single-center experience using anakinra for steroid-refractory immune effector cell-associated neurotoxicity syndrome (ICANS). J Immunother Cancer. 2022 01; 10(1). PMID: 34996813; PMCID: PMC8744112.
    Citations: 4     Fields:    Translation:Humans
  4. Wehrli M, Maus MV. New CARs on and off the road: challenges and new developments in CAR-T cell therapy. Curr Opin Pharmacol. 2021 08; 59:116-126. PMID: 34198161.
    Citations:    Fields:    Translation:HumansCells
  5. Hamzic S, Schärer D, Offer SM, Meulendijks D, Nakas C, Diasio RB, Fontana S, Wehrli M, Schürch S, Amstutz U, Largiadèr CR. Haplotype structure defines effects of common DPYD variants c.85T > C (rs1801265) and c.496A > G (rs2297595) on dihydropyrimidine dehydrogenase activity: Implication for 5-fluorouracil toxicity. Br J Clin Pharmacol. 2021 08; 87(8):3234-3243. PMID: 33491253.
    Citations: 4     Fields:    Translation:Humans
  6. Wehrli M, Schneider C, Cortinas-Elizondo F, Verschoor D, Frias Boligan K, Adams OJ, Hlushchuk R, Engelmann C, Daudel F, Villiger PM, Seibold F, Yawalkar N, Vonarburg C, Miescher S, Lötscher M, Kaufmann T, Münz C, Mueller C, Djonov V, Simon HU, von Gunten S. IgA Triggers Cell Death of Neutrophils When Primed by Inflammatory Mediators. J Immunol. 2020 11 15; 205(10):2640-2648. PMID: 33008951.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  7. Schmidts A, Wehrli M, Maus MV. Toward Better Understanding and Management of CAR-T Cell-Associated Toxicity. Annu Rev Med. 2021 01 27; 72:365-382. PMID: 32776808.
    Citations: 4     Fields:    Translation:HumansCells
  8. Lybrand DB, Naiman M, Laumann JM, Boardman M, Petshow S, Hansen K, Scott G, Wehrli M. Destruction complex dynamics: Wnt/ß-catenin signaling alters Axin-GSK3ß interactions in vivo. Development. 2019 07 02; 146(13). PMID: 31189665.
    Citations: 8     Fields:    Translation:AnimalsCells
  9. Neppl C, Kaderli RM, Trepp R, Schmitt AM, Berger MD, Wehrli M, Seiler CA, Langer R. Histology of Nivolumab-Induced Thyroiditis. Thyroid. 2018 12; 28(12):1727-1728. PMID: 30319070.
    Citations: 7     Fields:    Translation:Humans
  10. Petshow S, Wehrli M. Preparation of Precisely Oriented Cryosections of Undistorted Drosophila Wing Imaginal Discs for High Resolution Confocal Imaging. Bio Protoc. 2018 Feb 05; 8(3). PMID: 30167436; PMCID: PMC6112823.
    Citations: 1     
  11. Wehrli M, Oppliger Leibundgut E, Gattiker HH, Manz MG, Müller AM, Goede JS. Response to Tyrosine Kinase Inhibitors in Myeloproliferative Neoplasia with 8p11 Translocation and CEP110-FGFR1 Rearrangement. Oncologist. 2017 04; 22(4):480-483. PMID: 28242791.
    Citations: 2     Fields:    Translation:HumansCells
  12. Schneider C, Illi M, Lötscher M, Wehrli M, von Gunten S. Isolation of Antibodies from Human Plasma, Saliva, Breast Milk, and Gastrointestinal Fluid. Methods Mol Biol. 2017; 1643:23-31. PMID: 28667527.
    Citations: 3     Fields:    Translation:Humans
  13. Wehrli M, Cortinas-Elizondo F, Hlushchuk R, Daudel F, Villiger PM, Miescher S, Zuercher AW, Djonov V, Simon HU, von Gunten S. Human IgA Fc receptor FcaRI (CD89) triggers different forms of neutrophil death depending on the inflammatory microenvironment. J Immunol. 2014 Dec 01; 193(11):5649-59. PMID: 25339672.
    Citations: 9     Fields:    Translation:HumansCells
  14. Wehrli M, Goede JS. [Primary immune thrombocytopenia]. Praxis (Bern 1994). 2014 Apr 23; 103(9):485-94; quiz 495-6. PMID: 24755495.
    Citations:    Fields:    Translation:Humans
  15. Jandus C, Boligan KF, Chijioke O, Liu H, Dahlhaus M, Démoulins T, Schneider C, Wehrli M, Hunger RE, Baerlocher GM, Simon HU, Romero P, Münz C, von Gunten S. Interactions between Siglec-7/9 receptors and ligands influence NK cell-dependent tumor immunosurveillance. J Clin Invest. 2014 Apr; 124(4):1810-20. PMID: 24569453; PMCID: PMC3973073.
    Citations: 151     Fields:    Translation:HumansAnimalsCells
  16. von Gunten S, Wehrli M, Simon HU. Cell death in immune thrombocytopenia: novel insights and perspectives. Semin Hematol. 2013 Jan; 50 Suppl 1:S109-15. PMID: 23664507.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  17. Sopory S, Kwon S, Wehrli M, Christian JL. Regulation of Dpp activity by tissue-specific cleavage of an upstream site within the prodomain. Dev Biol. 2010 Oct 01; 346(1):102-12. PMID: 20659445.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  18. Blank F, Wehrli M, Lehmann A, Baum O, Gehr P, von Garnier C, Rothen-Rutishauser BM. Macrophages and dendritic cells express tight junction proteins and exchange particles in an in vitro model of the human airway wall. Immunobiology. 2011 Jan-Feb; 216(1-2):86-95. PMID: 20362352.
    Citations: 29     Fields:    Translation:HumansCellsPHPublic Health
  19. Kremer SA, Erdeniz N, Peterson-Nedry W, Swanson EA, Wehrli M. In vivo analysis in Drosophila reveals differential requirements of contact residues in Axin for interactions with GSK3beta or beta-catenin. Dev Biol. 2010 Jan 01; 337(1):110-23. PMID: 19850033.
    Citations: 4     Fields:    Translation:AnimalsCells
  20. Peterson-Nedry W, Erdeniz N, Kremer S, Yu J, Baig-Lewis S, Wehrli M. Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo. Dev Biol. 2008 Aug 01; 320(1):226-41. PMID: 18561909.
    Citations: 36     Fields:    Translation:AnimalsCells
  21. Baig-Lewis S, Peterson-Nedry W, Wehrli M. Wingless/Wnt signal transduction requires distinct initiation and amplification steps that both depend on Arrow/LRP. Dev Biol. 2007 Jun 01; 306(1):94-111. PMID: 17433287; PMCID: PMC1950126.
    Citations: 20     Fields:    Translation:AnimalsCells
  22. Rives AF, Rochlin KM, Wehrli M, Schwartz SL, DiNardo S. Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing. Dev Biol. 2006 May 01; 293(1):268-83. PMID: 16530179.
    Citations: 41     Fields:    Translation:AnimalsCells
  23. Tolwinski NS, Wehrli M, Rives A, Erdeniz N, DiNardo S, Wieschaus E. Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity. Dev Cell. 2003 Mar; 4(3):407-18. PMID: 12636921.
    Citations: 126     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.