Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Bo Zhang, Ph.D.


Nankai University, ChinaBS07/2001Mathematics
Nankai University, ChinaMS07/2004Statistics
University of Minnesota, Minneapolis, MNPhD08/2009Statistics (Major) and Biostatistics (Minor)
Johnson & Johnson Pharmaceutical Research and Development, Raritan, NJInternship08/2008Biostatistics and Clinical Trials
National Institute of Child Health and Human Development, NIH, Bethesda, MDFellowship09/2011Biostatistics and Data Sciences

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ye S, Liang Y, Zhang B. Bayesian functional mixed-effects models with grouped smoothness for analyzing time-course gene expression data. Current Bioinformatics. 2020; forthcoming.
  2. Jiang X, Liu W, Zhang B. A note on the prediction of frailties with misspecified shared frailty models. Journal of Statistical Computation and Simulation. 2020; forthcoming.
  3. Li X, Anderson SJ, Shiffman S, Zhang B. Time-varying coefficient cumulative gap time models for intensive longitudinal ecological momentary assessment data with missingness. Journal of Applied Statistics. 2020; forthcoming.
  4. Liu W, Haran JP, Ash AS, Allison JJ, Ye S, Tjia J, Bucci V, Zhang B. High-dimensional causal mediation analysis with a large number of mediators clumping at zero to assess the contribution of the microbiome to the risk of bacterial pathogen colonization in older adults. Current Bioinformatics. 2020; 15:671-696.
  5. Wang S, Wang C, Shi F, Tao E, Zhu G, Li J, Feng J, Wang X, Guo J, Zheng Q, Zhang B. An evaluation of treatments and survival rates for pancreatic adenocarcinoma through survival analysis with inverse probability of treatment weighting. Journal of Pancreatology. 2020; forthcoming.
  6. Liu X, Zhang B, Tang L, Zhang Z, Zhang N, Allison JJ, Srivastava DK, Zhang H. Are marginalized two-part models superior to non-marginalized two-part models for count data with excess zeroes? Estimation of marginal effects, model misspecification, and model selection. Health Services and Outcomes Research Methodology. 2020; 18(3):175-214.
  7. Guo J, Zhu Y, Fang L, Zhang B, Liu D, Fu M, Wang X. The Relationship Between Being Bullied and Addictive Internet Use Among Chinese Rural Adolescents: The Mediating Effect of Adult Attachment. J Interpers Violence. 2020 Oct 21; 886260520966681. PMID: 33084482.
    Citations:    Fields:    
  8. Shi F, Wang C, Kong Y, Yang L, Li J, Zhu G, Guo J, Zheng Q, Zhang B, Wang S. Assessing the Survival Benefit of Surgery and Various Types of Radiation Therapy for Treatment of Hepatocellular Carcinoma: Evidence from the Surveillance, Epidemiology, and End Results Registries. J Hepatocell Carcinoma. 2020; 7:201-218. PMID: 33117754.
  9. Guo J, Fu M, Liu D, Zhang B, Wang X, van IJzendoorn MH. Is the psychological impact of exposure to COVID-19 stronger in adolescents with pre-pandemic maltreatment experiences? A survey of rural Chinese adolescents. Child Abuse Negl. 2020 12; 110(Pt 2):104667. PMID: 32859393.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  10. Huang L, Tang L, Zhang B, Zhang Z, Zhang H. Comparison of different computational implementations on fitting generalized linear mixed-effects models for repeated count measures. Journal of Statistical Computation and Simulation. 2020; 86(12):2392-2404.
  11. Liu X, Chen W, Chen T, Zhang H, Zhang B. Marginal effects and incremental effects in two-part models for endogenous healthcare utilization in health services research. Health Services and Outcomes Research Methodology. 2020; 20(2-3):111-139.
  12. Shi F, Yu C, Yang L, Li F, Lun J, Gao W, Xu Y, Xiao Y, Shankara SB, Zheng Q, Zhang B, Wang S. Exploring the Dynamics of Hemorrhagic Fever with Renal Syndrome Incidence in East China Through Seasonal Autoregressive Integrated Moving Average Models. Infect Drug Resist. 2020; 13:2465-2475. PMID: 32801786.
    Citations: 1     
  13. Chen Q, Chu X, Wang S, Zhang B. A Triple-Difference Approach to Re-Evaluating the Impact of China's New Cooperative Medical Scheme on Incidences of Chronic Diseases Among Older Adults in Rural Communities. Risk Manag Healthc Policy. 2020; 13:643-659. PMID: 32617028.
  14. Liu D, Xi J, Hall BJ, Fu M, Zhang B, Guo J, Feng X. Attitudes toward aging, social support and depression among older adults: Difference by urban and rural areas in China. J Affect Disord. 2020 09 01; 274:85-92. PMID: 32469837.
    Citations: 2     Fields:    
  15. Kang L, Ye S, Jing K, Fan Y, Chen Q, Zhang N, Zhang B. A Segmented Logistic Regression Approach to Evaluating Change in Caesarean Section Rate with Reform of Birth Planning Policy in Two Regions in China from 2012 to 2016. Risk Manag Healthc Policy. 2020; 13:245-253. PMID: 32256135.
    Citations: 1     
  16. Ye S, Zhang H, Shi F, Guo J, Wang S, Zhang B. Ensemble Learning to Improve the Prediction of Fetal Macrosomia and Large-for-Gestational Age. J Clin Med. 2020 Jan 31; 9(2). PMID: 32023935.
    Citations: 1     
  17. Chen T, Zhang H, Zhang B. A semiparametric marginalized zero-inflated model for analyzing healthcare utilization panel data with missingness. Journal of Applied Statistics. 2019; 46(16):2862-2883.
  18. Zhang B, Shankara SB, Ye S, Zhang H. Design and analysis of high-risk medical device clinical trials for diabetes monitoring and treatment: A review. Journal of Pancreatology. 2019; 2(4):123-130.
  19. Zhang S, Chen Q, Zhang B. Understanding Healthcare Utilization In China Through The Andersen Behavioral Model: Review Of Evidence From The China Health And Nutrition Survey. Risk Manag Healthc Policy. 2019; 12:209-224. PMID: 31807101.
    Citations: 2     
  20. Liu Y, Ye S, Xiao X, Sun C, Wang G, Wang G, Zhang B. Machine Learning For Tuning, Selection, And Ensemble Of Multiple Risk Scores For Predicting Type 2 Diabetes. Risk Manag Healthc Policy. 2019; 12:189-198. PMID: 31807099.
    Citations: 2     
  21. Liu W, Ye S, Barton BA, Fischer MA, Lawrence C, Rahn EJ, Danila MI, Saag KG, Harris PA, Lemon SC, Allison JJ, Zhang B. Simulation-based power and sample size calculation for designing interrupted time series analyses of count outcomes in evaluation of health policy interventions. Contemp Clin Trials Commun. 2020 Mar; 17:100474. PMID: 31886433.
    Citations: 2     
  22. Kang L, Gu H, Ye S, Xu B, Jing K, Zhang N, Zhang B. Rural-urban disparities in caesarean section rates in minority areas in China: evidence from electronic health records. J Int Med Res. 2020 Feb; 48(2):300060519877996. PMID: 31566034.
    Citations:    Fields:    
  23. Liu Y, Ye S, Xiao X, Zhou T, Yang S, Wang G, Sun C, Zhang B, Wang G. Association of diabetes mellitus with hepatitis B and hepatitis C virus infection: evidence from an epidemiological study. Infect Drug Resist. 2019; 12:2875-2883. PMID: 31686868.
  24. Tang L, Zhang H, Zhang B. A note on error bars as a graphical representation of the variability of data in biomedical research. Journal of Pancreatology. 2019; 2(3):69-71.
  25. Zhang B, Ye S, Shankara SB, Zhang H, Zheng Q. Neutral diagnosis: An innovative concept for medical device clinical trials. Contemp Clin Trials Commun. 2019 Dec; 16:100436. PMID: 31485547.
  26. Zhang B, Liu W, Lemon SC, Barton BA, Fischer MA, Lawrence C, Rahn EJ, Danila MI, Saag KG, Harris PA, Allison JJ. Design, analysis, power, and sample size calculation for three-phase interrupted time series analysis in evaluation of health policy interventions. J Eval Clin Pract. 2020 Jun; 26(3):826-841. PMID: 31429175.
    Citations:    Fields:    
  27. Shi W, Wu J, Tan Q, Hu CM, Zhang X, Pan HQ, Yang Z, He MY, Yu M, Zhang B, Xie WP, Wang H. Plasma indoleamine 2,3-dioxygenase activity as a potential biomarker for early diagnosis of multidrug-resistant tuberculosis in tuberculosis patients. Infect Drug Resist. 2019; 12:1265-1276. PMID: 31190914.
    Citations: 3     
  28. Wang W, Cong N, Chen T, Zhang H, Zhang B. A note on misspecification in general linear models with correlated errors for the analysis of crossover clinical trials. PLoS One. 2019; 14(3):e0213436. PMID: 30870443.
    Citations: 1     Fields:    Translation:Humans
  29. Zhang N, Lu SF, Zhou Y, Zhang B, Crawford S, Gurwitz JH. Body Mass Index and 30-Day Adverse Outcomes Among Newly Admitted Residents to Skilled Nursing Facilities. J Am Med Dir Assoc. 2019 03; 20(3):312-316. PMID: 30824219.
    Citations:    Fields:    Translation:Humans
  30. Winer KK, Kelly A, Johns A, Zhang B, Dowdy K, Kim L, Reynolds JC, Albert PS, Cutler GB. Long-Term Parathyroid Hormone 1-34 Replacement Therapy in Children with Hypoparathyroidism. J Pediatr. 2018 12; 203:391-399.e1. PMID: 30470382.
    Citations: 3     Fields:    Translation:Humans
  31. Zhang H, Tang L, Kong Y, Chen T, Liu X, Zhang Z, Zhang B. Distribution-free models for latent mixed population responses in a longitudinal setting with missing data. Stat Methods Med Res. 2019 Oct-Nov; 28(10-11):3273-3285. PMID: 30246608.
    Citations: 1     Fields:    Translation:Humans
  32. Zhang N, Lu SF, Zhou Y, Zhang B, Copeland L, Gurwitz JH. Body Mass Index, Falls, and Hip Fractures Among Nursing Home Residents. J Gerontol A Biol Sci Med Sci. 2018 09 11; 73(10):1403-1409. PMID: 29506037.
    Citations: 2     Fields:    Translation:Humans
  33. Zhang B, Liu W, Zhang N, Ash AS, Allison JJ. A collection of marginalized two-part random-effects models for analyzing medical expenditure panel data: Impact of the New Cooperative Medical Scheme on healthcare expenditures in China. Stat Methods Med Res. 2019 08; 28(8):2494-2523. PMID: 29945495.
    Citations: 1     Fields:    Translation:Humans
  34. Hu Y, Miller M, Zhang B, Nguyen TT, Nielsen MK, Aroian RV. In vivo and in vitro studies of Cry5B and nicotinic acetylcholine receptor agonist anthelmintics reveal a powerful and unique combination therapy against intestinal nematode parasites. PLoS Negl Trop Dis. 2018 05; 12(5):e0006506. PMID: 29775454.
    Citations: 4     Fields:    Translation:HumansAnimals
  35. Nwosu BU, Zhang B, Ayyoub SS, Choi S, Villalobos-Ortiz TR, Alonso LC, Barton BA. Children with type 1 diabetes who experienced a honeymoon phase had significantly lower LDL cholesterol 5 years after diagnosis. PLoS One. 2018; 13(5):e0196912. PMID: 29768449.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  36. Jiang X, Guo X, Zhang N, Wang B, Zhang B. Robust multivariate nonparametric tests for detection of two-sample location shift in clinical trials. PLoS One. 2018; 13(4):e0195894. PMID: 29672555.
    Citations: 2     Fields:    Translation:Humans
  37. Liu X, Winter B, Tang L, Zhang B, Zhang Z, Zhang H. Simulating comparisons of different computing algorithms fitting zero-inflated Poisson models for zero abundant counts. Journal of Statistical Computation and Simulation. 2017; 87(13):2609-2621.
  38. Chen Q, Xu J, Zhao J, Zhang B. Endogenous schooling, school proximity and returns to rural schooling in northwestern China. China Agricultural Economic Review. 2017; 9(2):270-286.
  39. Zhang B, Liu W, Hu Y. Estimating marginal and incremental effects in the analysis of medical expenditure panel data using marginalized two-part random-effects generalized Gamma models: Evidence from China healthcare cost data. Stat Methods Med Res. 2018 10; 27(10):3039-3061. PMID: 28139170.
    Citations:    Fields:    
  40. Liu W, Zhang Z, Schroeder RJ, Ho M, Zhang B, Long C, Zhang H, Irony TZ. Joint Estimation of Treatment and Placebo Effects in Clinical Trials with Longitudinal Blinding Assessments. J Am Stat Assoc. 2016; 111(514):538-548. PMID: 27110045.
    Citations: 2     
  41. Wang W, Zhang B. Assessing natural direct and indirect effects for a continuous exposure and a dichotomous outcome. Journal of Statistical Theory and Practice. 2016; 10(3):574-587.
  42. Zhang B, Liu W, Zhang H, Chen Q, Zhang Z. Composite likelihood and maximum likelihood methods for joint latent class modeling of disease prevalence and high-dimensional semicontinuous biomarker data. Computational Statistics. 2016; 31(2):425-449.
  43. Zhang B, Liu W, Zhang H, Chen Q, Zhang Z. A note on misspecification in joint modeling of correlated data with informative cluster sizes. Journal of Statistical Planning and Inference. 2016; 170:46-63.
  44. Liu W, Zhang B, Zhang Z, Tao J, Branscum AJ. Model selection in finite mixture of regression models: a Bayesian approach with innovative weighted g-priors and reversible jump Markov chain Monte Carlo implementation. Journal of Statistical Computation and Simulation. 2015; 85(12):2456-2478.
  45. Zhang B, Liu W, Zhang Z, Qu Y, Chen Z, Albert PS. Modeling of correlated data with informative cluster sizes: An evaluation of joint modeling and within-cluster resampling approaches. Stat Methods Med Res. 2017 Aug; 26(4):1881-1895. PMID: 26113386.
    Citations: 2     Fields:    Translation:Animals
  46. Zhang H, He H, Lu N, Zhu L, Zhang B, Zhang Z, Tang L. A non-parametric model to address overdispersed count response in a longitudinal data setting with missingness. Stat Methods Med Res. 2017 Jun; 26(3):1461-1475. PMID: 25944850.
    Citations:    Fields:    Translation:Humans
  47. Qu Y, Meeden GD, Zhang B. An objective stepwise Bayes approach to small area estimation. Journal of Statistical Computation and Simulation. 2015; 85(7):1474-1494.
  48. Liu W, Pantoja-Galicia N, Zhang B, Kotz RM, Pennello G, Zhang H, Jacob J, Zhang Z. Generalized linear mixed models for multi-reader multi-case studies of diagnostic tests. Stat Methods Med Res. 2017 Jun; 26(3):1373-1388. PMID: 25847911.
    Citations: 1     Fields:    Translation:Humans
  49. Liu W, Zhang B, Zhang Z, Chen B, Zhou X. A pseudo-likelihood approach for estimating diagnostic accuracy of multiple binary medical tests. Computational Statistics & Data Analysis. 2015; 84:85-98.
  50. Liu W, Zhang B, Zhang H, Zhang Z. Likelihood-based methods for evaluating principal surrogacy in augmented vaccine trials. Stat Methods Med Res. 2017 04; 26(2):984-996. PMID: 25549966.
    Citations:    Fields:    Translation:Humans
  51. Gaddini GW, Grant KA, Woodall A, Stull C, Maddalozzo GF, Zhang B, Turner RT, Iwaniec UT. Twelve months of voluntary heavy alcohol consumption in male rhesus macaques suppresses intracortical bone remodeling. Bone. 2015 Feb; 71:227-36. PMID: 25451322.
    Citations: 9     Fields:    Translation:HumansAnimals
  52. Zhang Z, Nie L, Soon G, Zhang B. Sensitivity analysis in non-inferiority trials with residual inconstancy after covariate adjustment. Journal of the Royal Statistical Society: Series C (Applied Statistics). 2014; 63(4):515-538.
  53. Zhang Z, Qu Y, Zhang B, Nie L, Soon G. Use of auxiliary covariates in estimating a biomarker-adjusted treatment effect model with clinical trial data. Stat Methods Med Res. 2016 10; 25(5):2103-2119. PMID: 24346166.
    Citations:    Fields:    Translation:Humans
  54. Zhang Z, Liu W, Zhang B, Tang L, Zhang J. Causal inference with missing exposure information: Methods and applications to an obstetric study. Stat Methods Med Res. 2016 10; 25(5):2053-2066. PMID: 24318273.
    Citations: 3     Fields:    Translation:Humans
  55. Liu C, Liu A, Zhang B, Zhang Z. Improved confidence intervals of a small probability from pooled testing with misclassification. Front Public Health. 2013; 1:39. PMID: 24350208.
    Citations: 1     
  56. Liu W, Zhang B, Zhang Z, Zhou XH. Joint modeling of transitional patterns of Alzheimer's disease. PLoS One. 2013; 8(9):e75487. PMID: 24073268.
    Citations: 1     Fields:    Translation:Humans
  57. Iwaniec UT, Turner RT, Smith BJ, Stoecker BJ, Rust A, Zhang B, Vasu VT, Gohil K, Cross CE, Traber MG. Evaluation of long-term vitamin E insufficiency or excess on bone mass, density, and microarchitecture in rodents. Free Radic Biol Med. 2013 Dec; 65:1209-1214. PMID: 24051180.
    Citations: 9     Fields:    Translation:Animals
  58. Zhang Z, Zhang B. A likelihood paradigm for clinical trials (with discussion). Journal of Statistical Theory and Practice. 2013; 7(2):157-177 (rejoinder: 196-203).
  59. Tang LL, Liu A, Chen Z, Schisterman EF, Zhang B, Miao Z. Nonparametric ROC summary statistics for correlated diagnostic marker data. Stat Med. 2013 Jun 15; 32(13):2209-20. PMID: 23055248.
    Citations: 2     Fields:    Translation:Humans
  60. Zhang B, Chen Z, Albert PS. Estimating diagnostic accuracy of raters without a gold standard by exploiting a group of experts. Biometrics. 2012 Dec; 68(4):1294-302. PMID: 23006010.
    Citations: 7     Fields:    Translation:Humans
  61. Schliep KC, Stanford JB, Chen Z, Zhang B, Dorais JK, Boiman Johnstone E, Hammoud AO, Varner MW, Louis GM, Peterson CM. Interrater and intrarater reliability in the diagnosis and staging of endometriosis. Obstet Gynecol. 2012 Jul; 120(1):104-12. PMID: 22914398.
    Citations: 9     Fields:    Translation:Humans
  62. Zhang B, Shen X, Mumford SL. Generalized Degrees of Freedom and Adaptive Model Selection in Linear Mixed-Effects Models. Comput Stat Data Anal. 2012 Mar 01; 56(3):574-586. PMID: 22090665.
    Citations: 1     
  63. Winer KK, Zhang B, Shrader JA, Peterson D, Smith M, Albert PS, Cutler GB. Synthetic human parathyroid hormone 1-34 replacement therapy: a randomized crossover trial comparing pump versus injections in the treatment of chronic hypoparathyroidism. J Clin Endocrinol Metab. 2012 Feb; 97(2):391-9. PMID: 22090268.
    Citations: 50     Fields:    Translation:Humans
  64. Zhang B, Chen Z, Albert PS. Latent class models for joint analysis of disease prevalence and high-dimensional semicontinuous biomarker data. Biostatistics. 2012 Jan; 13(1):74-88. PMID: 21908867.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  65. Chen Z, Zhang B, Albert PS. A joint modeling approach to data with informative cluster size: robustness to the cluster size model. Stat Med. 2011 Jul 10; 30(15):1825-36. PMID: 21495060.
    Citations: 7     Fields:    Translation:Animals
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Zhang's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (169)
Co-Authors (1)
Similar People (60)
Same Department 
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.