Harvard Catalyst Profiles

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Yuka Okusha, D.D.S.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Feng Y, Tran MT, Lu Y, Htike K, Okusha Y, Sogawa C, Eguchi T, Kadowaki T, Sakai E, Tsukuba T, Okamoto K. Rab34 plays a critical role as a bidirectional regulator of osteoclastogenesis. Cell Biochem Funct. 2022 Mar 14. PMID: 35285960.
    Citations:    Fields:    
  2. Lang BJ, Prince TL, Okusha Y, Bunch H, Calderwood SK. Heat shock proteins in cell signaling and cancer. Biochim Biophys Acta Mol Cell Res. 2022 03; 1869(3):119187. PMID: 34906617.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Calderwood SK, Borges TJ, Eguchi T, Lang BJ, Murshid A, Okusha Y, Prince TL. Extracellular Hsp90 and protection of neuronal cells through Nrf2. Biochem Soc Trans. 2021 11 01; 49(5):2299-2306. PMID: 34415306.
    Citations:    Fields:    Translation:HumansCells
  4. Tran MT, Okusha Y, Feng Y, Sogawa C, Eguchi T, Kadowaki T, Sakai E, Tsukuba T, Okamoto K. A novel role of HSP90 in regulating osteoclastogenesis by abrogating Rab11b-driven transport. Biochim Biophys Acta Mol Cell Res. 2021 09; 1868(10):119096. PMID: 34242681.
    Citations:    Fields:    Translation:AnimalsCells
  5. Lang BJ, Guerrero ME, Prince TL, Okusha Y, Bonorino C, Calderwood SK. The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response. Arch Toxicol. 2021 06; 95(6):1943-1970. PMID: 34003342.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  6. Sogawa C, Eguchi T, Namba Y, Okusha Y, Aoyama E, Ohyama K, Okamoto K. Gel-Free 3D Tumoroids with Stem Cell Properties Modeling Drug Resistance to Cisplatin and Imatinib in Metastatic Colorectal Cancer. Cells. 2021 02 06; 10(2). PMID: 33562088.
    Citations: 2     Fields:    Translation:AnimalsCells
  7. Tran MT, Okusha Y, Feng Y, Morimatsu M, Wei P, Sogawa C, Eguchi T, Kadowaki T, Sakai E, Okamura H, Naruse K, Tsukuba T, Okamoto K. The Inhibitory Role of Rab11b in Osteoclastogenesis through Triggering Lysosome-Induced Degradation of c-Fms and RANK Surface Receptors. Int J Mol Sci. 2020 Dec 08; 21(24). PMID: 33302495.
    Citations: 2     Fields:    Translation:AnimalsCells
  8. Okusha Y, Tran MT, Itagaki M, Sogawa C, Eguchi T, Okui T, Kadowaki T, Sakai E, Tsukuba T, Okamoto K. Rab11A Functions as a Negative Regulator of Osteoclastogenesis through Dictating Lysosome-Induced Proteolysis of c-fms and RANK Surface Receptors. Cells. 2020 10 31; 9(11). PMID: 33142674.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  9. Ono K, Sogawa C, Kawai H, Tran MT, Taha EA, Lu Y, Oo MW, Okusha Y, Okamura H, Ibaragi S, Takigawa M, Kozaki KI, Nagatsuka H, Sasaki A, Okamoto K, Calderwood SK, Eguchi T. Triple knockdown of CDC37, HSP90-alpha and HSP90-beta diminishes extracellular vesicles-driven malignancy events and macrophage M2 polarization in oral cancer. J Extracell Vesicles. 2020 May 31; 9(1):1769373. PMID: 33144925.
    Citations: 11     Fields:    
  10. Taha EA, Sogawa C, Okusha Y, Kawai H, Oo MW, Elseoudi A, Lu Y, Nagatsuka H, Kubota S, Satoh A, Okamoto K, Eguchi T. Knockout of MMP3 Weakens Solid Tumor Organoids and Cancer Extracellular Vesicles. Cancers (Basel). 2020 05 16; 12(5). PMID: 32429403.
    Citations: 12     
  11. Okusha Y, Eguchi T, Tran MT, Sogawa C, Yoshida K, Itagaki M, Taha EA, Ono K, Aoyama E, Okamura H, Kozaki KI, Calderwood SK, Takigawa M, Okamoto K. Extracellular Vesicles Enriched with Moonlighting Metalloproteinase Are Highly Transmissive, Pro-Tumorigenic, and Trans-Activates Cellular Communication Network Factor (CCN2/CTGF): CRISPR against Cancer. Cancers (Basel). 2020 Apr 04; 12(4). PMID: 32260433.
    Citations: 9     
  12. Eguchi T, Sogawa C, Ono K, Matsumoto M, Tran MT, Okusha Y, Lang BJ, Okamoto K, Calderwood SK. Cell Stress Induced Stressome Release Including Damaged Membrane Vesicles and Extracellular HSP90 by Prostate Cancer Cells. Cells. 2020 03 19; 9(3). PMID: 32204513.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  13. Sogawa C, Eguchi T, Tran MT, Ishige M, Trin K, Okusha Y, Taha EA, Lu Y, Kawai H, Sogawa N, Takigawa M, Calderwood SK, Okamoto K, Kozaki KI. Antiparkinson Drug Benztropine Suppresses Tumor Growth, Circulating Tumor Cells, and Metastasis by Acting on SLC6A3/DAT and Reducing STAT3. Cancers (Basel). 2020 Feb 24; 12(2). PMID: 32102440.
    Citations: 13     
  14. Sogawa C, Eguchi T, Okusha Y, Ono K, Ohyama K, Iizuka M, Kawasaki R, Hamada Y, Takigawa M, Sogawa N, Okamoto K, Kozaki KI. A Reporter System Evaluates Tumorigenesis, Metastasis, ß-catenin/MMP Regulation, and Druggability. Tissue Eng Part A. 2019 10; 25(19-20):1413-1425. PMID: 30734664.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  15. Hasegawa K, Okui T, Shimo T, Ibaragi S, Kawai H, Ryumon S, Kishimoto K, Okusha Y, Monsur Hassan NM, Sasaki A. Lactate Transporter Monocarboxylate Transporter 4 Induces Bone Pain in Head and Neck Squamous Cell Carcinoma. Int J Mol Sci. 2018 Oct 25; 19(11). PMID: 30366393.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  16. Namba Y, Sogawa C, Okusha Y, Kawai H, Itagaki M, Ono K, Murakami J, Aoyama E, Ohyama K, Asaumi JI, Takigawa M, Okamoto K, Calderwood SK, Kozaki KI, Eguchi T. Depletion of Lipid Efflux Pump ABCG1 Triggers the Intracellular Accumulation of Extracellular Vesicles and Reduces Aggregation and Tumorigenesis of Metastatic Cancer Cells. Front Oncol. 2018; 8:376. PMID: 30364132.
    Citations: 22     
  17. Okusha Y, Eguchi T, Sogawa C, Okui T, Nakano K, Okamoto K, Kozaki KI. The intranuclear PEX domain of MMP involves proliferation, migration, and metastasis of aggressive adenocarcinoma cells. J Cell Biochem. 2018 09; 119(9):7363-7376. PMID: 29761931.
    Citations: 12     Fields:    Translation:AnimalsCells
  18. Eguchi T, Sogawa C, Okusha Y, Uchibe K, Iinuma R, Ono K, Nakano K, Murakami J, Itoh M, Arai K, Fujiwara T, Namba Y, Murata Y, Ohyama K, Shimomura M, Okamura H, Takigawa M, Nakatsura T, Kozaki KI, Okamoto K, Calderwood SK. Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment. PLoS One. 2018; 13(2):e0191109. PMID: 29415026.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  19. Morisawa A, Okui T, Shimo T, Ibaragi S, Okusha Y, Ono M, Nguyen TTH, Hassan NMM, Sasaki A. Ammonium tetrathiomolybdate enhances the antitumor effects of cetuximab via the suppression of osteoclastogenesis in head and neck squamous carcinoma. Int J Oncol. 2018 Mar; 52(3):989-999. PMID: 29328370.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  20. Okusha Y, Hirai Y, Maezawa H, Hisadome K, Inoue N, Yamazaki Y, Funahashi M. Effects of intraperitoneally administered L-histidine on food intake, taste, and visceral sensation in rats. J Physiol Sci. 2017 Jul; 67(4):467-474. PMID: 27535568.
    Citations: 2     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.