Harvard Catalyst Profiles

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Arnold Stephen Freedman, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21CA103244 (FREEDMAN, ARNOLD S.) Apr 23, 2004 - Mar 31, 2007
    NIH/NCI
    CpG Plus Rituximab Therapy in Follicular Lymphoma
    Role: Principal Investigator
  2. R21CA099324 (FREEDMAN, ARNOLD S.) Sep 12, 2002 - Aug 31, 2005
    NIH/NCI
    Etanercept Therapy in Follicular Lymphoma
    Role: Principal Investigator
  3. R01CA081494 (FREEDMAN, ARNOLD S.) Aug 1, 1999 - Jul 31, 2002
    NIH/NCI
    INTEGRIN SIGNALING IN ACUTE LYMPHOBLASTIC LEUKEMIA
    Role: Principal Investigator
  4. P01CA066996 (EBERT, BENJAMIN LEVINE) Apr 25, 1997 - Mar 31, 2008
    NIH/NCI
    Development of Novel Therapeutic Strategies in Human Leukemias
    Role: Co-Principal Investigator
  5. R01CA055207 (FREEDMAN, ARNOLD S.) Jul 8, 1991 - May 31, 2000
    NIH/NCI
    GERMINAL CENTER INTERACTIONS OF NORMAL/MALIGNANT B CELLS
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Merryman RW, Edwin N, Redd R, Bsat J, Chase M, LaCasce A, Freedman A, Jacobson C, Fisher D, Ng S, Crombie J, Kim A, Odejide O, Davids MS, Brown JR, Jacene H, Cashen A, Bartlett NL, Mehta-Shah N, Ghobadi A, Kahl B, Joyce R, Armand P, Jacobsen E. Rituximab/bendamustine and rituximab/cytarabine induction therapy for transplant-eligible mantle cell lymphoma. Blood Adv. 2020 Mar 10; 4(5):858-867. PMID: 32126141.
    Citations:    
  2. Frigault MJ, Armand P, Redd RA, Jeter E, Merryman RW, Coleman KC, Herrera AF, Dahi P, Nieto Y, LaCasce AS, Fisher DC, Ng SY, Odejide OO, Freedman AS, Kim AI, Crombie JL, Jacobson CA, Jacobsen ED, Wong JL, Bsat J, Patel SS, Ritz J, Rodig SJ, Shipp MA, Chen YB, Joyce RM. PD-1 blockade for diffuse large B-cell lymphoma after autologous stem cell transplantation. Blood Adv. 2020 Jan 14; 4(1):122-126. PMID: 31917843.
    Citations:    
  3. Freedman A, Jacobsen E. Follicular lymphoma: 2020 update on diagnosis and management. Am J Hematol. 2020 03; 95(3):316-327. PMID: 31814159.
    Citations:    
  4. Lampson BL, Kim HT, Davids MS, Abramson JS, Freedman AS, Jacobson CA, Armand PA, Joyce RM, Arnason JE, Rassenti LZ, Kipps TJ, Fein J, Fernandes SM, Hanna JR, Fisher DC, Brown JR. Efficacy results of a phase 2 trial of first-line idelalisib plus ofatumumab in chronic lymphocytic leukemia. Blood Adv. 2019 04 09; 3(7):1167-1174. PMID: 30967392.
    Citations:    
  5. Armand P, Chen YB, Redd RA, Joyce RM, Bsat J, Jeter E, Merryman RW, Coleman KC, Dahi PB, Nieto Y, LaCasce AS, Fisher DC, Ng SY, Odejide OO, Freedman AS, Kim AI, Crombie JL, Jacobson CA, Jacobsen ED, Wong JL, Patel SS, Ritz J, Rodig SJ, Shipp MA, Herrera AF. PD-1 blockade with pembrolizumab for classical Hodgkin lymphoma after autologous stem cell transplantation. Blood. 2019 07 04; 134(1):22-29. PMID: 30952672.
    Citations:    
  6. Fung M, Jacobsen E, Freedman A, Prestes D, Farmakiotis D, Gu X, Nguyen PL, Koo S. Increased Risk of Infectious Complications in Older Patients With Indolent Non-Hodgkin Lymphoma Exposed to Bendamustine. Clin Infect Dis. 2019 01 07; 68(2):247-255. PMID: 29800121.
    Citations: 1     Fields:    
  7. Stathis A, Flinn IW, Madan S, Maddocks K, Freedman A, Weitman S, Zucca E, Munteanu MC, Lia Palomba M. Safety, tolerability, and preliminary activity of IMGN529, a CD37-targeted antibody-drug conjugate, in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: a dose-escalation, phase I study. Invest New Drugs. 2018 10; 36(5):869-876. PMID: 29453628.
    Citations: 1     Fields:    
  8. Freedman A. Follicular lymphoma: 2018 update on diagnosis and management. Am J Hematol. 2018 Feb; 93(2):296-305. PMID: 29314206.
    Citations: 1     Fields:    Translation:Humans
  9. Shields H, Li J, Pelletier S, Wang H, Freedman R, Mamon H, Ng A, Freedman A, Come S, Avigan D, Huberman M, Recht A. Persistence of dysphagia and odynophagia after mediastinal radiation and chemotherapy in patients with lung cancer or lymphoma. Dis Esophagus. 2017 02 01; 30(2):1-8. PMID: 27247116.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  10. Gibson CJ, Lindsley RC, Tchekmedyian V, Mar BG, Shi J, Jaiswal S, Bosworth A, Francisco L, He J, Bansal A, Morgan EA, Lacasce AS, Freedman AS, Fisher DC, Jacobsen E, Armand P, Alyea EP, Koreth J, Ho V, Soiffer RJ, Antin JH, Ritz J, Nikiforow S, Forman SJ, Michor F, Neuberg D, Bhatia R, Bhatia S, Ebert BL. Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma. J Clin Oncol. 2017 May 10; 35(14):1598-1605. PMID: 28068180.
    Citations: 18     Fields:    Translation:HumansCells
  11. Herrera AF, Mei M, Low L, Kim HT, Griffin GK, Song JY, Merryman RW, Bedell V, Pak C, Sun H, Paris T, Stiller T, Brown JR, Budde LE, Chan WC, Chen R, Davids MS, Freedman AS, Fisher DC, Jacobsen ED, Jacobson CA, LaCasce AS, Murata-Collins J, Nademanee AP, Palmer JM, Pihan GA, Pillai R, Popplewell L, Siddiqi T, Sohani AR, Zain J, Rosen ST, Kwak LW, Weinstock DM, Forman SJ, Weisenburger DD, Kim Y, Rodig SJ, Krishnan A, Armand P. Relapsed or Refractory Double-Expressor and Double-Hit Lymphomas Have Inferior Progression-Free Survival After Autologous Stem-Cell Transplantation. J Clin Oncol. 2017 Jan; 35(1):24-31. PMID: 28034071.
    Citations: 4     Fields:    Translation:Humans
  12. Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, Andreeff M, Armand P, Ballen KK, Barzaghi-Rinaudo P, Cahill S, Clark RA, Cooke VG, Davids MS, DeAngelo DJ, Dorfman DM, Eaton H, Ebert BL, Etchin J, Firestone B, Fisher DC, Freedman AS, Galinsky IA, Gao H, Garcia JS, Garnache-Ottou F, Graubert TA, Gutierrez A, Halilovic E, Harris MH, Herbert ZT, Horwitz SM, Inghirami G, Intlekofer AM, Ito M, Izraeli S, Jacobsen ED, Jacobson CA, Jeay S, Jeremias I, Kelliher MA, Koch R, Konopleva M, Kopp N, Kornblau SM, Kung AL, Kupper TS, LeBoeuf NR, LaCasce AS, Lees E, Li LS, Look AT, Murakami M, Muschen M, Neuberg D, Ng SY, Odejide OO, Orkin SH, Paquette RR, Place AE, Roderick JE, Ryan JA, Sallan SE, Shoji B, Silverman LB, Soiffer RJ, Steensma DP, Stegmaier K, Stone RM, Tamburini J, Thorner AR, van Hummelen P, Wadleigh M, Wiesmann M, Weng AP, Wuerthner JU, Williams DA, Wollison BM, Lane AA, Letai A, Bertagnolli MM, Ritz J, Brown M, Long H, Aster JC, Shipp MA, Griffin JD, Weinstock DM. The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell. 2016 07 11; 30(1):183. PMID: 27479034.
    Citations: 13     Fields:    
  13. Jacobson CA, Freedman AS. Is There a Best Initial Treatment for a New Patient With Low Grade Follicular Lymphoma. Curr Hematol Malig Rep. 2016 06; 11(3):218-23. PMID: 26995595.
    Citations:    Fields:    Translation:Humans
  14. Lampson BL, Kasar SN, Matos TR, Morgan EA, Rassenti L, Davids MS, Fisher DC, Freedman AS, Jacobson CA, Armand P, Abramson JS, Arnason JE, Kipps TJ, Fein J, Fernandes S, Hanna J, Ritz J, Kim HT, Brown JR. Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity. Blood. 2016 07 14; 128(2):195-203. PMID: 27247136.
    Citations: 41     Fields:    Translation:HumansCTClinical Trials
  15. Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, Andreeff M, Armand P, Ballen KK, Barzaghi-Rinaudo P, Cahill S, Clark RA, Cooke VG, Davids MS, DeAngelo DJ, Dorfman DM, Eaton H, Ebert BL, Etchin J, Firestone B, Fisher DC, Freedman AS, Galinsky IA, Gao H, Garcia JS, Garnache-Ottou F, Graubert TA, Gutierrez A, Halilovic E, Harris MH, Herbert ZT, Horwitz SM, Inghirami G, Intlekofer AM, Ito M, Izraeli S, Jacobsen ED, Jacobson CA, Jeay S, Jeremias I, Kelliher MA, Koch R, Konopleva M, Kopp N, Kornblau SM, Kung AL, Kupper TS, LeBoeuf NR, LaCasce AS, Lees E, Li LS, Look AT, Murakami M, Muschen M, Neuberg D, Ng SY, Odejide OO, Orkin SH, Paquette RR, Place AE, Roderick JE, Ryan JA, Sallan SE, Shoji B, Silverman LB, Soiffer RJ, Steensma DP, Stegmaier K, Stone RM, Tamburini J, Thorner AR, van Hummelen P, Wadleigh M, Wiesmann M, Weng AP, Wuerthner JU, Williams DA, Wollison BM, Lane AA, Letai A, Bertagnolli MM, Ritz J, Brown M, Long H, Aster JC, Shipp MA, Griffin JD, Weinstock DM. The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell. 2016 04 11; 29(4):574-586. PMID: 27070704.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  16. Armand P, Redd R, Bsat J, Mayuram S, Giardino A, Fisher DC, LaCasce AS, Jacobson C, Davids MS, Brown JR, Weng L, Wilkins J, Faham M, Freedman AS, Joyce R, Jacobsen ED. A phase 2 study of Rituximab-Bendamustine and Rituximab-Cytarabine for transplant-eligible patients with mantle cell lymphoma. Br J Haematol. 2016 Apr; 173(1):89-95. PMID: 26729345.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  17. Freedman A. Follicular lymphoma: 2015 update on diagnosis and management. Am J Hematol. 2015 Dec; 90(12):1171-8. PMID: 26769125.
    Citations: 2     Fields:    Translation:Humans
  18. Jacobson CA, Freedman AS. Rethinking Prognosis and Therapy for Follicular Lymphoma. J Clin Oncol. 2015 Aug 10; 33(23):2489-91. PMID: 26169620.
    Citations:    Fields:    Translation:Humans
  19. Brown JR, Tesar B, Yu L, Werner L, Takebe N, Mikler E, Reynolds HM, Thompson C, Fisher DC, Neuberg D, Freedman AS. Obatoclax in combination with fludarabine and rituximab is well-tolerated and shows promising clinical activity in relapsed chronic lymphocytic leukemia. Leuk Lymphoma. 2015; 56(12):3336-42. PMID: 25971907.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  20. Jacobson CA, Freedman AS. Is observation dead in follicular lymphoma? Still appropriate. J Natl Compr Canc Netw. 2015 Mar; 13(3):367-70. PMID: 25736012.
    Citations: 3     Fields:    Translation:Humans
  21. Ganapathi KA, Pittaluga S, Odejide OO, Freedman AS, Jaffe ES. Early lymphoid lesions: conceptual, diagnostic and clinical challenges. Haematologica. 2014 Sep; 99(9):1421-32. PMID: 25176983.
    Citations: 8     Fields:    Translation:HumansCells
  22. Jacobsen E, Pozdnyakova O, Redd R, Fisher DC, Dorfman DM, Dal Cin P, LaCasce A, Armand P, Hochberg E, Cote G, Shahsafaei A, Neuberg D, Brown JR, Freedman AS. Imatinib mesylate lacks efficacy in relapsed/refractory peripheral T cell lymphoma. Leuk Lymphoma. 2015 Apr; 56(4):993-8. PMID: 25012943.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  23. Rendleman J, Antipin Y, Reva B, Adaniel C, Przybylo JA, Dutra-Clarke A, Hansen N, Heguy A, Huberman K, Borsu L, Paltiel O, Ben-Yehuda D, Brown JR, Freedman AS, Sander C, Zelenetz A, Klein RJ, Shao Y, Lacher M, Vijai J, Offit K, Kirchhoff T. Genetic variation in DNA repair pathways and risk of non-Hodgkin's lymphoma. PLoS One. 2014; 9(7):e101685. PMID: 25010664.
    Citations: 2     Fields:    Translation:HumansCells
  24. Levy R, Ganjoo KN, Leonard JP, Vose JM, Flinn IW, Ambinder RF, Connors JM, Berinstein NL, Belch AR, Bartlett NL, Nichols C, Emmanouilides CE, Timmerman JM, Gregory SA, Link BK, Inwards DJ, Freedman AS, Matous JV, Robertson MJ, Kunkel LA, Ingolia DE, Gentles AJ, Liu CL, Tibshirani R, Alizadeh AA, Denney DW. Active idiotypic vaccination versus control immunotherapy for follicular lymphoma. J Clin Oncol. 2014 Jun 10; 32(17):1797-803. PMID: 24799467.
    Citations: 13     Fields:    Translation:HumansCellsCTClinical Trials
  25. Freedman A. Follicular lymphoma: 2014 update on diagnosis and management. Am J Hematol. 2014 Apr; 89(4):429-36. PMID: 24687887.
    Citations: 17     Fields:    Translation:HumansCells
  26. Fanale M, Assouline S, Kuruvilla J, Solal-Céligny P, Heo DS, Verhoef G, Corradini P, Abramson JS, Offner F, Engert A, Dyer MJ, Carreon D, Ewald B, Baeck J, Younes A, Freedman AS. Phase IA/II, multicentre, open-label study of the CD40 antagonistic monoclonal antibody lucatumumab in adult patients with advanced non-Hodgkin or Hodgkin lymphoma. Br J Haematol. 2014 Jan; 164(2):258-65. PMID: 24219359.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  27. Jacobson CA, Freedman AS. One size does not fit all in follicular lymphoma. J Clin Oncol. 2013 Sep 20; 31(27):3307-8. PMID: 23960176.
    Citations: 1     Fields:    Translation:Humans
  28. Armand P, Oki Y, Neuberg DS, Faham M, Cummings C, Klinger M, Weng L, Bhattar S, Lacasce AS, Jacobsen ED, Davids MS, Jacobson C, Fisher DC, Brown JR, Fowler NH, Alma Rodriguez M, Wallace MJ, Neelapu SS, Rodig S, Younes A, Freedman AS. Detection of circulating tumour DNA in patients with aggressive B-cell non-Hodgkin lymphoma. Br J Haematol. 2013 Oct; 163(1):123-6. PMID: 23795711.
    Citations: 19     Fields:    Translation:HumansCells
  29. Brown JR, Messmer B, Werner L, Davids MS, Mikler E, Supko JG, Fisher DC, LaCasce AS, Armand P, Jacobsen E, Dalton V, Tesar B, Fernandes SM, McDonough S, Ritz J, Rassenti L, Kipps TJ, Neuberg D, Freedman AS. A phase I study of escalated dose subcutaneous alemtuzumab given weekly with rituximab in relapsed chronic lymphocytic leukemia/small lymphocytic lymphoma. Haematologica. 2013 Jun; 98(6):964-70. PMID: 23645694.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  30. Jacobson CA, Freedman AS. First-line treatment of indolent lymphoma: axing CHOP? Lancet. 2013 Apr 06; 381(9873):1163-5. PMID: 23433738.
    Citations: 1     Fields:    Translation:Humans
  31. Russo AL, Chen YH, Martin NE, Vinjamoori A, Luthy SK, Freedman A, Michaelson EM, Silver B, Mauch PM, Ng AK. Low-dose involved-field radiation in the treatment of non-hodgkin lymphoma: predictors of response and treatment failure. Int J Radiat Oncol Biol Phys. 2013 May 01; 86(1):121-7. PMID: 23414765.
    Citations: 5     Fields:    Translation:Humans
  32. Armand P, Welch S, Kim HT, LaCasce AS, Jacobsen ED, Davids MS, Jacobson C, Fisher DC, Brown JR, Coughlin E, Freedman AS, Chen YB. Prognostic factors for patients with diffuse large B cell lymphoma and transformed indolent lymphoma undergoing autologous stem cell transplantation in the positron emission tomography era. Br J Haematol. 2013 Mar; 160(5):608-17. PMID: 23278720.
    Citations: 10     Fields:    Translation:Humans
  33. Barnes JA, Jacobsen E, Feng Y, Freedman A, Hochberg EP, LaCasce AS, Armand P, Joyce R, Sohani AR, Rodig SJ, Neuberg D, Fisher DC, Abramson JS. Everolimus in combination with rituximab induces complete responses in heavily pretreated diffuse large B-cell lymphoma. Haematologica. 2013 Apr; 98(4):615-9. PMID: 23144193.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  34. Freedman A. Follicular lymphoma: 2012 update on diagnosis and management. Am J Hematol. 2012 Oct; 87(10):988-95. PMID: 23001911.
    Citations: 11     Fields:    Translation:HumansCellsPHPublic Health
  35. Jacobson CA, Freedman AS. Early stage follicular lymphoma, current management and controversies. Curr Opin Oncol. 2012 Sep; 24(5):475-9. PMID: 22820411.
    Citations: 1     Fields:    Translation:Humans
  36. Giardino AA, Shinagare AB, Shinagare SA, Dewar R, Weckstein D, Mauch P, Ramaiya NH, Freedman AS. Primary bone lymphoma involving bilateral tibia. Am J Hematol. 2012 Sep; 87(9):924-5. PMID: 22641233.
    Citations: 2     Fields:    Translation:Humans
  37. Brown JR, Hanna M, Tesar B, Werner L, Pochet N, Asara JM, Wang YE, Dal Cin P, Fernandes SM, Thompson C, Macconaill L, Wu CJ, Van de Peer Y, Correll M, Regev A, Neuberg D, Freedman AS. Integrative genomic analysis implicates gain of PIK3CA at 3q26 and MYC at 8q24 in chronic lymphocytic leukemia. Clin Cancer Res. 2012 Jul 15; 18(14):3791-802. PMID: 22623730.
    Citations: 22     Fields:    Translation:HumansCells
  38. Brown JR, Hanna M, Tesar B, Pochet N, Vartanov A, Fernandes SM, Werner L, Ash M, Roden CA, MacConaill L, Hainz U, Longtine J, Wang YE, Correll M, Van de Peer Y, Regev A, Wu C, Neuberg D, Freedman AS. Germline copy number variation associated with Mendelian inheritance of CLL in two families. Leukemia. 2012 Jul; 26(7):1710-3. PMID: 22382893.
    Citations: 4     Fields:    Translation:Humans
  39. Lane AA, Armand P, Feng Y, Neuberg DS, Abramson JS, Brown JR, Fisher DC, LaCasce AS, Jacobsen ED, McAfee SL, Spitzer TR, Freedman AS, Chen YB. Risk factors for development of pneumonitis after high-dose chemotherapy with cyclophosphamide, BCNU and etoposide followed by autologous stem cell transplant. Leuk Lymphoma. 2012 Jun; 53(6):1130-6. PMID: 22132836.
    Citations: 3     Fields:    Translation:Humans
  40. Fox AM, Dosoretz AP, Mauch PM, Chen YH, Fisher DC, LaCasce AS, Freedman AS, Silver B, Ng AK. Predictive factors for radiation pneumonitis in Hodgkin lymphoma patients receiving combined-modality therapy. Int J Radiat Oncol Biol Phys. 2012 May 01; 83(1):277-83. PMID: 22019238.
    Citations: 8     Fields:    Translation:Humans
  41. Freedman A. Follicular lymphoma: 2011 update on diagnosis and management. Am J Hematol. 2011 Sep; 86(9):768-75. PMID: 21850659.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  42. Mabbott NA, Kenneth Baillie J, Kobayashi A, Donaldson DS, Ohmori H, Yoon SO, Freedman AS, Freeman TC, Summers KM. Expression of mesenchyme-specific gene signatures by follicular dendritic cells: insights from the meta-analysis of microarray data from multiple mouse cell populations. Immunology. 2011 Aug; 133(4):482-98. PMID: 21635249.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  43. Sweetenham JW, Freedman AS. Early initial therapy of advanced follicular lymphoma: the need for vigilance. Leuk Lymphoma. 2011 Mar; 52(3):355-7. PMID: 21323517.
    Citations:    Fields:    Translation:HumansPHPublic Health
  44. Furman RR, Grossbard ML, Johnson JL, Pecora AL, Cassileth PA, Jung SH, Peterson BA, Nadler LM, Freedman A, Bayer RL, Bartlett NL, Hurd DD, Cheson BD. A phase III study of anti-B4-blocked ricin as adjuvant therapy post-autologous bone marrow transplant: CALGB 9254. Leuk Lymphoma. 2011 Apr; 52(4):587-96. PMID: 21275630.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  45. Abou-Nassar KE, Stevenson KE, Antin JH, McDermott K, Ho VT, Cutler CS, LaCasce AS, Jacobsen ED, Fisher DC, Soiffer RJ, Alyea EP, Koreth J, Freedman AS. (90)Y-ibritumomab tiuxetan followed by reduced-intensity conditioning and allo-SCT in patients with advanced follicular lymphoma. Bone Marrow Transplant. 2011 Dec; 46(12):1503-9. PMID: 21258420.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  46. Jacobsen ED, Kim HT, Ho VT, Cutler CS, Koreth J, Fisher DC, Armand P, Alyea EP, Freedman AS, Soiffer RJ, Antin JH. A large single-center experience with allogeneic stem-cell transplantation for peripheral T-cell non-Hodgkin lymphoma and advanced mycosis fungoides/Sezary syndrome. Ann Oncol. 2011 Jul; 22(7):1608-1613. PMID: 21252059.
    Citations: 22     Fields:    Translation:HumansCTClinical Trials
  47. Brown JR, Abramson J, Hochberg E, Mikler E, Dalton V, Werner L, Reynolds H, Thompson C, McDonough SM, Kuang Y, Ritz J, Neuberg D, Freedman AS. A phase I study of lenalidomide in combination with fludarabine and rituximab in previously untreated CLL/SLL. Leukemia. 2010 Nov; 24(11):1972-5. PMID: 20844565.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  48. Setlur SR, Ihm C, Tchinda J, Shams S, Werner L, Cho EK, Thompson C, Phillips K, Rassenti LZ, Kipps TJ, Neuberg D, Freedman AS, Lee C, Brown JR. Comparison of familial and sporadic chronic lymphocytic leukaemia using high resolution array comparative genomic hybridization. Br J Haematol. 2010 Nov; 151(4):336-45. PMID: 20812997.
    Citations: 6     Fields:    Translation:HumansCells
  49. Yoon SO, Zhang X, Freedman AS, Zahrieh D, Lossos IS, Li L, Choi YS. Down-regulation of CD9 expression and its correlation to tumor progression in B lymphomas. Am J Pathol. 2010 Jul; 177(1):377-86. PMID: 20566742.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  50. Pozdnyakova O, Spieler PJ, Abraham J, Freedman AS, Kutok JL. Epstein-barr virus-associated diffuse large B-cell lymphoma in an immunocompetent woman. J Clin Oncol. 2010 Feb 10; 28(5):e75-8. PMID: 19917837.
    Citations: 3     Fields:    Translation:HumansCells
  51. Brown JR, Freedman AS. ASCT in follicular lymphoma. Nat Rev Clin Oncol. 2009 Jul; 6(7):380-2. PMID: 19561632.
    Citations:    Fields:    Translation:Humans
  52. Friedberg JW, Kelly JL, Neuberg D, Peterson DR, Kutok JL, Salloum R, Brenn T, Fisher DC, Ronan E, Dalton V, Rich L, Marquis D, Sims P, Rothberg PG, Liesveld J, Fisher RI, Coffman R, Mosmann T, Freedman AS. Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma. Br J Haematol. 2009 Aug; 146(3):282-91. PMID: 19519691.
    Citations: 27     Fields:    Translation:HumansCTClinical Trials
  53. Freedman A, Neelapu SS, Nichols C, Robertson MJ, Djulbegovic B, Winter JN, Bender JF, Gold DP, Ghalie RG, Stewart ME, Esquibel V, Hamlin P. Placebo-controlled phase III trial of patient-specific immunotherapy with mitumprotimut-T and granulocyte-macrophage colony-stimulating factor after rituximab in patients with follicular lymphoma. J Clin Oncol. 2009 Jun 20; 27(18):3036-43. PMID: 19414675.
    Citations: 37     Fields:    Translation:HumansCellsCTClinical Trials
  54. Brown JR, Friedberg JW, Feng Y, Scofield S, Phillips K, Dal Cin P, Joyce R, Takvorian RW, Fisher DC, Fisher RI, Liesveld J, Marquis D, Neuberg D, Freedman AS. A phase 2 study of concurrent fludarabine and rituximab for the treatment of marginal zone lymphomas. Br J Haematol. 2009 Jun; 145(6):741-8. PMID: 19344412.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  55. Armand P, Gannamaneni S, Kim HT, Cutler CS, Ho VT, Koreth J, Alyea EP, LaCasce AS, Jacobsen ED, Fisher DC, Brown JR, Canellos GP, Freedman AS, Soiffer RJ, Antin JH. Improved survival in lymphoma patients receiving sirolimus for graft-versus-host disease prophylaxis after allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning. J Clin Oncol. 2008 Dec 10; 26(35):5767-74. PMID: 19001324.
    Citations: 41     Fields:    Translation:Humans
  56. Brown JR, Levine RL, Thompson C, Basile G, Gilliland DG, Freedman AS. Systematic genomic screen for tyrosine kinase mutations in CLL. Leukemia. 2008 Oct; 22(10):1966-9. PMID: 18754031.
    Citations: 11     Fields:    Translation:Humans
  57. Brown JR, Neuberg D, Phillips K, Reynolds H, Silverstein J, Clark JC, Ash M, Thompson C, Fisher DC, Jacobsen E, LaCasce AS, Freedman AS. Prevalence of familial malignancy in a prospectively screened cohort of patients with lymphoproliferative disorders. Br J Haematol. 2008 Nov; 143(3):361-8. PMID: 18729853.
    Citations: 8     Fields:    Translation:Humans
  58. Luthy SK, Ng AK, Silver B, Degnan KO, Fisher DC, Freedman AS, Mauch PM. Response to low-dose involved-field radiotherapy in patients with non-Hodgkin's lymphoma. Ann Oncol. 2008 Dec; 19(12):2043-7. PMID: 18647962.
    Citations: 4     Fields:    Translation:Humans
  59. Friedberg J, Jacobsen E, Neuberg D, Kutok J, Munoz O, Boussiotis V, Reynolds H, Fisher D, Szot A, Van Den Abbeele A, Freedman A. Targeting the follicular lymphoma microenvironment through blockade of TNFalpha with etanercept. Leuk Lymphoma. 2008 May; 49(5):902-9. PMID: 18464109.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  60. Armand P, Kim HT, Ho VT, Cutler CS, Koreth J, Antin JH, LaCasce AS, Jacobsen ED, Fisher DC, Brown JR, Canellos GP, Freedman AS, Soiffer RJ, Alyea EP. Allogeneic transplantation with reduced-intensity conditioning for Hodgkin and non-Hodgkin lymphoma: importance of histology for outcome. Biol Blood Marrow Transplant. 2008 Apr; 14(4):418-25. PMID: 18342784.
    Citations: 37     Fields:    Translation:Humans
  61. LaCasce AS, Freedman AS. Antibody and immunomodulatory agents in the treatment of indolent non-Hodgkin's lymphoma. Semin Hematol. 2008 Apr; 45(2):85-9. PMID: 18381102.
    Citations: 2     Fields:    Translation:Humans
  62. Brown JR, Feng Y, Gribben JG, Neuberg D, Fisher DC, Mauch P, Nadler LM, Freedman AS. Long-term survival after autologous bone marrow transplantation for follicular lymphoma in first remission. Biol Blood Marrow Transplant. 2007 Sep; 13(9):1057-65. PMID: 17697968.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  63. Rohatiner AZ, Nadler L, Davies AJ, Apostolidis J, Neuberg D, Matthews J, Gribben JG, Mauch PM, Lister TA, Freedman AS. Myeloablative therapy with autologous bone marrow transplantation for follicular lymphoma at the time of second or subsequent remission: long-term follow-up. J Clin Oncol. 2007 Jun 20; 25(18):2554-9. PMID: 17515573.
    Citations: 33     Fields:    Translation:Humans
  64. Parrett BM, Orgill DP, Marsee DK, Freedman AS, Raut CP. Novel presentation of intraneural nodular fasciitis of the sciatic nerve. J Peripher Nerv Syst. 2007 Mar; 12(1):61-3. PMID: 17374106.
    Citations: 2     Fields:    Translation:Humans
  65. Friedberg JW, Freedman AS. Antibody and immunomodulatory agents in treatment of indolent non-Hodgkin's lymphoma. Curr Treat Options Oncol. 2006 Jul; 7(4):276-84. PMID: 16916488.
    Citations: 2     Fields:    Translation:Humans
  66. Jacobsen E, Van Den Abbeele AD, Neuberg D, Li S, Fisher DC, Friedberg J, Barnes AS, Yap JT, Kutok J, Freedman AS. Inhibiting TNFa with etanercept in relapsed/refractory follicular lymphoma. J Clin Oncol. 2006 Jun 20; 24(18_suppl):17525. PMID: 27954314.
    Citations:    
  67. Freedman AS. Non-transplant-related treatment options in follicular lymphoma. Biol Blood Marrow Transplant. 2006 Jan; 12(1 Suppl 1):53-8. PMID: 16399586.
    Citations:    Fields:    Translation:Humans
  68. Zubair AC, Kao G, Daley H, Schott D, Freedman A, Ritz J. CD34(+) CD38(-) and CD34(+) HLA-DR(-) cells in BM stem cell grafts correlate with short-term engraftment but have no influence on long-term hematopoietic reconstitution after autologous transplantation. Cytotherapy. 2006; 8(4):399-407. PMID: 16923616.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  69. Jacobsen E, Lomo L, Briccetti F, Longtine J, Freedman A. Follicular lymphoma with bilateral testicular and epididymal involvement: case report and review of the literature. Leuk Lymphoma. 2005 Nov; 46(11):1663-6. PMID: 16236619.
    Citations: 1     Fields:    Translation:Humans
  70. Gribben JG, Zahrieh D, Stephans K, Bartlett-Pandite L, Alyea EP, Fisher DC, Freedman AS, Mauch P, Schlossman R, Sequist LV, Soiffer RJ, Marshall B, Neuberg D, Ritz J, Nadler LM. Autologous and allogeneic stem cell transplantations for poor-risk chronic lymphocytic leukemia. Blood. 2005 Dec 15; 106(13):4389-96. PMID: 16131571.
    Citations: 45     Fields:    Translation:HumansCTClinical Trials
  71. Brown JR, Yeckes H, Friedberg JW, Neuberg D, Kim H, Nadler LM, Freedman AS. Increasing incidence of late second malignancies after conditioning with cyclophosphamide and total-body irradiation and autologous bone marrow transplantation for non-Hodgkin's lymphoma. J Clin Oncol. 2005 Apr 01; 23(10):2208-14. PMID: 15753460.
    Citations: 24     Fields:    Translation:Humans
  72. Freedman AS. Biology and management of histologic transformation of indolent lymphoma. Hematology Am Soc Hematol Educ Program. 2005; 314-20. PMID: 16304397.
    Citations: 7     Fields:    Translation:HumansCells
  73. Jacobsen E, Freedman A. B-cell purging in autologous stem-cell transplantation for non-Hodgkin lymphoma. Lancet Oncol. 2004 Dec; 5(12):711-7. PMID: 15581541.
    Citations: 4     Fields:    Translation:HumansCells
  74. Munoz O, Fend F, de Beaumont R, Husson H, Astier A, Freedman AS. TGFbeta-mediated activation of Smad1 in B-cell non-Hodgkin's lymphoma and effect on cell proliferation. Leukemia. 2004 Dec; 18(12):2015-25. PMID: 15470494.
    Citations: 13     Fields:    Translation:HumansCells
  75. Friedberg JW, Kim H, McCauley M, Hessel EM, Sims P, Fisher DC, Nadler LM, Coffman RL, Freedman AS. Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-alpha/beta-inducible gene expression, without significant toxicity. Blood. 2005 Jan 15; 105(2):489-95. PMID: 15358617.
    Citations: 27     Fields:    Translation:HumansCTClinical Trials
  76. Brown JR, Weng AP, Freedman AS. Hodgkin disease associated with T-cell non-Hodgkin lymphomas: case reports and review of the literature. Am J Clin Pathol. 2004 May; 121(5):701-8. PMID: 15151210.
    Citations: 4     Fields:    Translation:Humans
  77. Astier AL, Svoboda M, Hinds E, De Beaumont R, Munoz O, Freedman AS. Integrins regulate survival of pre-B-ALL cells through differential IAP and caspase-7 ubiquitination and degradation. Leukemia. 2004 Apr; 18(4):873-5. PMID: 14973500.
    Citations:    Fields:    Translation:Humans
  78. Jacobsen E, Freedman A. An update on the role of high-dose therapy with autologous or allogeneic stem cell transplantation in mantle cell lymphoma. Curr Opin Oncol. 2004 Mar; 16(2):106-13. PMID: 15075900.
    Citations: 3     Fields:    Translation:Humans
  79. Zubair AC, Zahrieh D, Daley H, Schott D, Gribben JG, Alyea EP, Schlossman R, Freedman A, Antin JH, Soiffer RJ, Neuberg D, Ritz J. Engraftment of autologous and allogeneic marrow HPCs after myeloablative therapy. Transfusion. 2004 Feb; 44(2):253-61. PMID: 14962317.
    Citations: 2     Fields:    Translation:HumansCells
  80. Brown JR, Gaudet G, Friedberg JW, Neuberg D, Mauch P, Kutok JL, Takvorian T, Fisher DC, Gribben JG, Kim H, Nadler LM, Freedman AS. Autologous bone marrow transplantation for marginal zone non-Hodgkin's lymphoma. Leuk Lymphoma. 2004 Feb; 45(2):315-20. PMID: 15101717.
    Citations: 3     Fields:    Translation:HumansCells
  81. Friedberg JW, Dong DA, Li S, Kim H, Stephans K, Noonan K, Neuberg D, Gribben JG, Fisher DC, Freedman AS, Takvorian T, Jurgens R, Battle TE, Frank DA. Oral fludarabine has significant activity in patients with previously untreated chronic lymphocytic leukemia, and leads to increased STAT1 levels in vivo. Leuk Res. 2004 Feb; 28(2):139-47. PMID: 14654078.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  82. Friedberg JW, Kim H, Li S, Neuberg D, Boyd K, Daley H, Fisher DC, Gribben JG, Spitzer T, Freedman AS. Ex vivo B cell depletion using the Eligix B Cell SC system and autologous peripheral blood stem cell transplantation in patients with follicular non-Hodgkin's lymphoma. Bone Marrow Transplant. 2003 Oct; 32(7):681-6. PMID: 13130315.
    Citations: 1     Fields:    Translation:HumansCellsCTClinical Trials
  83. Lestou VS, Gascoyne RD, Sehn L, Ludkovski O, Chhanabhai M, Klasa RJ, Husson H, Freedman AS, Connors JM, Horsman DE. Multicolour fluorescence in situ hybridization analysis of t(14;18)-positive follicular lymphoma and correlation with gene expression data and clinical outcome. Br J Haematol. 2003 Sep; 122(5):745-59. PMID: 12930384.
    Citations: 7     Fields:    Translation:HumansCells
  84. Zubair A, Zahrieh D, Daley H, Schott D, Gribben JG, Freedman A, Ritz J. Early neutrophil engraftment following autologous BMT provides a functional predictor of long-term hematopoietic reconstitution. Transfusion. 2003 May; 43(5):614-21. PMID: 12702183.
    Citations: 7     Fields:    Translation:HumansCells
  85. Husson H, Freedman AS, Cardoso AA, Schultze J, Munoz O, Strola G, Kutok J, Carideo EG, De Beaumont R, Caligaris-Cappio F, Ghia P. CXCL13 (BCA-1) is produced by follicular lymphoma cells: role in the accumulation of malignant B cells. Br J Haematol. 2002 Nov; 119(2):492-5. PMID: 12406091.
    Citations: 12     Fields:    Translation:HumansCells
  86. Astier AL, Xu R, Svoboda M, Hinds E, Munoz O, de Beaumont R, Crean CD, Gabig T, Freedman AS. Temporal gene expression profile of human precursor B leukemia cells induced by adhesion receptor: identification of pathways regulating B-cell survival. Blood. 2003 Feb 01; 101(3):1118-27. PMID: 12393420.
    Citations: 4     Fields:    Translation:HumansCells
  87. Sarkar S, Svoboda M, de Beaumont R, Freedman AS. The role of Aktand RAFTK in beta1 integrin mediated survival of precursor B-acute lymphoblastic leukemia cells. Leuk Lymphoma. 2002 Aug; 43(8):1663-71. PMID: 12400610.
    Citations: 6     Fields:    Translation:HumansCells
  88. Friedberg JW, Neuberg D, Gribben JG, Fisher DC, Canning C, Koval M, Poor CM, Green LM, Daley J, Soiffer R, Ritz J, Freedman AS. Combination immunotherapy with rituximab and interleukin 2 in patients with relapsed or refractory follicular non-Hodgkin's lymphoma. Br J Haematol. 2002 Jun; 117(4):828-34. PMID: 12060117.
    Citations: 25     Fields:    Translation:HumansCells
  89. Gaudet G, Friedberg JW, Weng A, Pinkus GS, Freedman AS. Breast lymphoma associated with breast implants: two case-reports and a review of the literature. Leuk Lymphoma. 2002 Jan; 43(1):115-9. PMID: 11908714.
    Citations: 22     Fields:    Translation:Humans
  90. Alyea EP, Weller E, Fisher DC, Freedman AS, Gribben JG, Lee S, Schlossman RL, Stone RM, Friedberg J, DeAngelo D, Liney D, Windawi S, Ng A, Mauch P, Antin JH, Soiffer RJ. Comparable outcome with T-cell-depleted unrelated-donor versus related-donor allogeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2002; 8(11):601-7. PMID: 12463479.
    Citations: 7     Fields:    Translation:HumansCells
  91. Husson H, Carideo EG, Neuberg D, Schultze J, Munoz O, Marks PW, Donovan JW, Chillemi AC, O'Connell P, Freedman AS. Gene expression profiling of follicular lymphoma and normal germinal center B cells using cDNA arrays. Blood. 2002 Jan 01; 99(1):282-9. PMID: 11756183.
    Citations: 27     Fields:    Translation:HumansCells
  92. Webb IJ, Friedberg nW, Gribben JG, Fisher DC, Spitzer T, Neuberg D, Jallow H, Kim H, Houde H, Monroy R, Schmittling R, Freedman AS. Effective purging of autologous hematopoietic stem cells using anti-B-cell monoclonal antibody-coated high-density microparticles prior to high-dose therapy for patients with non-Hodgkin's lymphoma. Biol Blood Marrow Transplant. 2002; 8(8):429-34. PMID: 12234168.
    Citations:    Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
  93. Alyea E, Neuberg D, Mauch P, Marcus K, Freedman A, Webb I, Anderson K, Schlossman R, Fisher D, Gribben J, Ritz J, Soiffer R. Effect of total body irradiation dose escalation on outcome following T-cell-depleted allogeneic bone marrow transplantation. Biol Blood Marrow Transplant. 2002; 8(3):139-44. PMID: 11939603.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  94. Klein U, Tu Y, Stolovitzky GA, Mattioli M, Cattoretti G, Husson H, Freedman A, Inghirami G, Cro L, Baldini L, Neri A, Califano A, Dalla-Favera R. Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells. J Exp Med. 2001 Dec 03; 194(11):1625-38. PMID: 11733577.
    Citations: 194     Fields:    Translation:HumansCells
  95. Husson H, Carideo EG, Cardoso AA, Lugli SM, Neuberg D, Munoz O, de Leval L, Schultze J, Freedman AS. MCP-1 modulates chemotaxis by follicular lymphoma cells. Br J Haematol. 2001 Dec; 115(3):554-62. PMID: 11736935.
    Citations: 9     Fields:    Translation:HumansCells
  96. Soiffer RJ, Weller E, Alyea EP, Mauch P, Webb IL, Fisher DC, Freedman AS, Schlossman RL, Gribben J, Lee S, Anderson KC, Marcus K, Stone RM, Antin JH, Ritz J. CD6+ donor marrow T-cell depletion as the sole form of graft-versus-host disease prophylaxis in patients undergoing allogeneic bone marrow transplant from unrelated donors. J Clin Oncol. 2001 Feb 15; 19(4):1152-9. PMID: 11181681.
    Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
  97. Friedberg JW, Neuberg D, Monson E, Jallow H, Nadler LM, Freedman AS. The impact of external beam radiation therapy prior to autologous bone marrow transplantation in patients with non-Hodgkin's lymphoma. Biol Blood Marrow Transplant. 2001; 7(8):446-53. PMID: 11569890.
    Citations:    Fields:    Translation:Humans
  98. Robinson SN, Freedman AS, Neuberg DS, Nadler LM, Mauch PM. Loss of marrow reserve from dose-intensified chemotherapy results in impaired hematopoietic reconstitution after autologous transplantation: CD34(+), CD34(+)38(-), and week-6 CAFC assays predict poor engraftment. Exp Hematol. 2000 Dec; 28(12):1325-33. PMID: 11146154.
    Citations: 5     Fields:    Translation:HumansCells
  99. Husson H, Lugli SM, Ghia P, Cardoso A, Roth A, Brohmi K, Carideo EG, Choi YS, Browning J, Freedman AS. Functional effects of TNF and lymphotoxin alpha1beta2 on FDC-like cells. Cell Immunol. 2000 Aug 01; 203(2):134-43. PMID: 11006011.
    Citations: 13     Fields:    Translation:HumansCells
  100. Freedman A, Friedberg JW, Gribben J. High-dose therapy for follicular lymphoma. Oncology (Williston Park). 2000 Mar; 14(3):321-6, 329; discussion 330-2, 338. PMID: 10742961.
    Citations: 2     Fields:    Translation:Humans
  101. Freedman AS, Neuberg D, Mauch P, Soiffer RJ, Anderson KC, Fisher DC, Schlossman R, Alyea EP, Takvorian T, Jallow H, Kuhlman C, Ritz J, Nadler LM, Gribben JG. Long-term follow-up of autologous bone marrow transplantation in patients with relapsed follicular lymphoma. Blood. 1999 Nov 15; 94(10):3325-33. PMID: 10552941.
    Citations: 31     Fields:    Translation:HumansCTClinical Trials
  102. Friedberg JW, Neuberg D, Stone RM, Alyea E, Jallow H, LaCasce A, Mauch PM, Gribben JG, Ritz J, Nadler LM, Soiffer RJ, Freedman AS. Outcome in patients with myelodysplastic syndrome after autologous bone marrow transplantation for non-Hodgkin's lymphoma. J Clin Oncol. 1999 Oct; 17(10):3128-35. PMID: 10506609.
    Citations: 22     Fields:    Translation:Humans
  103. Grossbard ML, Multani PS, Freedman AS, O'Day S, Gribben JG, Rhuda C, Neuberg D, Nadler LM. A Phase II study of adjuvant therapy with anti-B4-blocked ricin after autologous bone marrow transplantation for patients with relapsed B-cell non-Hodgkin's lymphoma. Clin Cancer Res. 1999 Sep; 5(9):2392-8. PMID: 10499609.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  104. Friedberg JW, Freedman AS. High-dose therapy and stem cell transplantation in follicular lymphoma. Ann Hematol. 1999 May; 78(5):203-11. PMID: 10391100.
    Citations: 2     Fields:    Translation:Humans
  105. Boussiotis VA, Freedman AS, Nadler LM. Bone marrow transplantation for low-grade lymphoma and chronic lymphocytic leukemia. Semin Hematol. 1999 Apr; 36(2):209-16. PMID: 10319389.
    Citations: 2     Fields:    Translation:Humans
  106. Dahia PL, Aguiar RC, Alberta J, Kum JB, Caron S, Sill H, Marsh DJ, Ritz J, Freedman A, Stiles C, Eng C. PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies. Hum Mol Genet. 1999 Feb; 8(2):185-93. PMID: 9931326.
    Citations: 60     Fields:    Translation:HumansCells
  107. Friedberg JW, Neuberg D, Gribben JG, Mauch P, Anderson KC, Soiffer RJ, Takvorian T, Fisher DC, Schlossman R, Jallow H, Kuhlman C, Ritz J, Freedman AS. Autologous bone marrow transplantation after histologic transformation of indolent B cell malignancies. Biol Blood Marrow Transplant. 1999; 5(4):262-8. PMID: 10465106.
    Citations: 6     Fields:    Translation:Humans
  108. Mach-Pascual S, Legare RD, Lu D, Kroon M, Neuberg D, Tantravahi R, Stone RM, Freedman AS, Nadler LM, Gribben JG, Gilliland DG. Predictive value of clonality assays in patients with non-Hodgkin's lymphoma undergoing autologous bone marrow transplant: a single institution study. Blood. 1998 Jun 15; 91(12):4496-503. PMID: 9616144.
    Citations: 8     Fields:    Translation:HumansCells
  109. Soiffer RJ, Freedman AS, Neuberg D, Fisher DC, Alyea EP, Gribben J, Schlossman RL, Bartlett-Pandite L, Kuhlman C, Murray C, Freeman A, Mauch P, Anderson KC, Nadler LM, Ritz J. CD6+ T cell-depleted allogeneic bone marrow transplantation for non-Hodgkin's lymphoma. Bone Marrow Transplant. 1998 Jun; 21(12):1177-81. PMID: 9674848.
    Citations: 3     Fields:    Translation:Humans
  110. Freedman AS, Neuberg D, Gribben JG, Mauch P, Soiffer RJ, Fisher DC, Anderson KC, Andersen N, Schlossman R, Kroon M, Ritz J, Aster J, Nadler LM. High-dose chemoradiotherapy and anti-B-cell monoclonal antibody-purged autologous bone marrow transplantation in mantle-cell lymphoma: no evidence for long-term remission. J Clin Oncol. 1998 Jan; 16(1):13-8. PMID: 9440717.
    Citations: 14     Fields:    Translation:HumansCells
  111. Ghia P, Boussiotis VA, Schultze JL, Cardoso AA, Dorfman DM, Gribben JG, Freedman AS, Nadler LM. Unbalanced expression of bcl-2 family proteins in follicular lymphoma: contribution of CD40 signaling in promoting survival. Blood. 1998 Jan 01; 91(1):244-51. PMID: 9414291.
    Citations: 19     Fields:    Translation:HumansCells
  112. Freedman AS, Gribben JG, Nadler LM. High dose therapy and autologous stem cell transplantation in follicular non-Hodgkin's lymphoma. Leuk Lymphoma. 1998 Jan; 28(3-4):219-30. PMID: 9517494.
    Citations: 3     Fields:    Translation:Humans
  113. Freedman A, Neuberg D, Mauch P, Gribben J, Soiffer R, Anderson K, Robertson M, Fisher DC, Schlossman R, Kroon M, Rhuda C, Kuhlman C, Ritz J, Nadler L. Cyclophosphamide, doxorubicin, vincristine, prednisone dose intensification with granulocyte colony-stimulating factor markedly depletes stem cell reserve for autologous bone marrow transplantation. Blood. 1997 Dec 15; 90(12):4996-5001. PMID: 9389719.
    Citations: 5     Fields:    Translation:HumansCells
  114. Astier A, Manié SN, Law SF, Canty T, Haghayghi N, Druker BJ, Salgia R, Golemis EA, Freedman AS. Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells. Leuk Lymphoma. 1997 Dec; 28(1-2):65-72. PMID: 9498705.
    Citations: 17     Fields:    Translation:HumansCells
  115. Andersen NS, Donovan JW, Borus JS, Poor CM, Neuberg D, Aster JC, Nadler LM, Freedman AS, Gribben JG. Failure of immunologic purging in mantle cell lymphoma assessed by polymerase chain reaction detection of minimal residual disease. Blood. 1997 Nov 15; 90(10):4212-21. PMID: 9354694.
    Citations: 12     Fields:    Translation:HumansCells
  116. Astier A, Manié SN, Avraham H, Hirai H, Law SF, Zhang Y, Golemis EA, Fu Y, Druker BJ, Haghayeghi N, Freedman AS, Avraham S. The related adhesion focal tyrosine kinase differentially phosphorylates p130Cas and the Cas-like protein, p105HEF1. J Biol Chem. 1997 Aug 08; 272(32):19719-24. PMID: 9242628.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  117. Manié SN, Astier A, Haghayeghi N, Canty T, Druker BJ, Hirai H, Freedman AS. Regulation of integrin-mediated p130(Cas) tyrosine phosphorylation in human B cells. A role for p59(Fyn) and SHP2. J Biol Chem. 1997 Jun 20; 272(25):15636-41. PMID: 9188452.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  118. Soiffer RJ, Fairclough D, Robertson M, Alyea E, Anderson K, Freedman A, Bartlett-Pandite L, Fisher D, Schlossman RL, Stone R, Murray C, Freeman A, Marcus K, Mauch P, Nadler L, Ritz J. CD6-depleted allogeneic bone marrow transplantation for acute leukemia in first complete remission. Blood. 1997 Apr 15; 89(8):3039-47. PMID: 9108425.
    Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
  119. Soiffer RJ, Mauch P, Fairclough D, Alyea E, Anderson K, Fisher D, Freedman A, Bartlett-Pandite L, Robertson M, Schlossman R, Gollob J, Marcus K, Murray C, Kuhlman C, Freeman A, Nadler L, Ritz J. CD6+ T cell depleted allogeneic bone marrow transplantation from genotypically HLA nonidentical related donors. Biol Blood Marrow Transplant. 1997 Apr; 3(1):11-7. PMID: 9209736.
    Citations: 4     Fields:    Translation:HumansCells
  120. Manié SN, Beck AR, Astier A, Law SF, Canty T, Hirai H, Druker BJ, Avraham H, Haghayeghi N, Sattler M, Salgia R, Griffin JD, Golemis EA, Freedman AS. Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells. J Biol Chem. 1997 Feb 14; 272(7):4230-6. PMID: 9020138.
    Citations: 36     Fields:    Translation:HumansCells
  121. Astier A, Avraham H, Manie SN, Groopman J, Canty T, Avraham S, Freedman AS. The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas. J Biol Chem. 1997 Jan 03; 272(1):228-32. PMID: 8995252.
    Citations: 52     Fields:    Translation:HumansCells
  122. Manié SN, Sattler M, Astier A, Phifer JS, Canty T, Morimoto C, Druker BJ, Salgia R, Griffin JD, Freedman AS. Tyrosine phosphorylation of the product of the c-cbl protooncogene is [corrected] induced after integrin stimulation. Exp Hematol. 1997 Jan; 25(1):45-50. PMID: 8989906.
    Citations: 6     Fields:    Translation:HumansCells
  123. Freedman AS, Gribben JG, Neuberg D, Mauch P, Soiffer RJ, Anderson KC, Pandite L, Robertson MJ, Kroon M, Ritz J, Nadler LM. High-dose therapy and autologous bone marrow transplantation in patients with follicular lymphoma during first remission. Blood. 1996 Oct 01; 88(7):2780-6. PMID: 8839876.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  124. Manie SN, Astier A, Wang D, Phifer JS, Chen J, Lazarovits AI, Morimoto C, Freedman AS. Stimulation of tyrosine phosphorylation after ligation of beta7 and beta1 integrins on human B cells. Blood. 1996 Mar 01; 87(5):1855-61. PMID: 8634433.
    Citations: 7     Fields:    Translation:HumansCells
  125. Freedman AS. Cell surface antigens in leukemias and lymphomas. Cancer Invest. 1996; 14(3):252-76. PMID: 8630688.
    Citations: 1     Fields:    Translation:HumansCells
  126. Huang MJ, Osborn L, Svahn J, Schiffer SB, Eliseo L, Zhou LJ, Rhynhart K, Benjamin CD, Freedman AS. Expression of vascular cell adhesion molecule-1 by follicular dendritic cells. Leuk Lymphoma. 1995 Jul; 18(3-4):259-64. PMID: 8535191.
    Citations: 2     Fields:    Translation:HumansCells
  127. Seiden MV, Schlossman R, Andersen J, Freeman A, Robertson M, Soiffer R, Freedman A, Mauch P, Ritz J, Nadler L, et al. Monoclonal antibody-purged bone marrow transplantation therapy for multiple myeloma. Leuk Lymphoma. 1995 Mar; 17(1-2):87-93. PMID: 7773166.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  128. Freedman AS, Wang D, Phifer JS, Manie SN. Role of follicular dendritic cells in the regulation of B cell proliferation. Curr Top Microbiol Immunol. 1995; 201:83-92. PMID: 7587354.
    Citations: 1     Fields:    Translation:Cells
  129. Stone RM, Neuberg D, Soiffer R, Takvorian T, Whelan M, Rabinowe SN, Aster JC, Leavitt P, Mauch P, Freedman AS, et al. Myelodysplastic syndrome as a late complication following autologous bone marrow transplantation for non-Hodgkin's lymphoma. J Clin Oncol. 1994 Dec; 12(12):2535-42. PMID: 7989927.
    Citations: 19     Fields:    Translation:Humans
  130. Gribben JG, Neuberg D, Barber M, Moore J, Pesek KW, Freedman AS, Nadler LM. Detection of residual lymphoma cells by polymerase chain reaction in peripheral blood is significantly less predictive for relapse than detection in bone marrow. Blood. 1994 Jun 15; 83(12):3800-7. PMID: 8204898.
    Citations: 18     Fields:    Translation:HumansCells
  131. O'Day SJ, Rabinowe SN, Neuberg D, Freedman AS, Soiffer RJ, Spector NA, Robertson MJ, Anderson K, Whelan M, Pesek K, et al. A phase II study of continuous infusion recombinant human granulocyte-macrophage colony-stimulating factor as an adjunct to autologous bone marrow transplantation for patients with non-Hodgkin's lymphoma in first remission. Blood. 1994 May 01; 83(9):2707-14. PMID: 8167349.
    Citations: 1     Fields:    Translation:HumansCellsCTClinical Trials
  132. Coderre J, Rubin P, Freedman A, Hansen J, Wooding TS, Joel D, Gash D. Selective ablation of rat brain tumors by boron neutron capture therapy. Int J Radiat Oncol Biol Phys. 1994 Mar 30; 28(5):1067-77. PMID: 8175391.
    Citations: 7     Fields:    Translation:Animals
  133. Freedman AS, Saporito L, Rhynhart K, Morimoto C, Nadler LM. Adhesion of follicular lymphoma cells to lymphoid germinal centers--a potential mechanism of tumor cell homing following autologous transplantation. Leuk Lymphoma. 1994 Mar; 13(1-2):47-52. PMID: 8025523.
    Citations: 1     Fields:    Translation:HumansCells
  134. Munro JM, Freedman AS, Aster JC, Gribben JG, Lee NC, Rhynhart KK, Banchereau J, Nadler LM. In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease. Blood. 1994 Feb 01; 83(3):793-8. PMID: 7507734.
    Citations: 18     Fields:    Translation:HumansCells
  135. Rohatiner AZ, Freedman A, Nadler L, Lim J, Lister TA. Myeloablative therapy with autologous bone marrow transplantation as consolidation therapy for follicular lymphoma. Ann Oncol. 1994; 5 Suppl 2:143-6. PMID: 8204513.
    Citations: 2     Fields:    Translation:HumansAnimals
  136. Anderson KC, Andersen J, Soiffer R, Freedman AS, Rabinowe SN, Robertson MJ, Spector N, Blake K, Murray C, Freeman A, et al. Monoclonal antibody-purged bone marrow transplantation therapy for multiple myeloma. Blood. 1993 Oct 15; 82(8):2568-76. PMID: 8400304.
    Citations: 7     Fields:    Translation:Humans
  137. Freedman AS, Nadler LM. Which patients with relapsed non-Hodgkin's lymphoma benefit from high-dose therapy and hematopoietic stem-cell transplantation? J Clin Oncol. 1993 Oct; 11(10):1841-3. PMID: 8105033.
    Citations: 2     Fields:    Translation:Humans
  138. Freedman AS. Expression and function of adhesion receptors on normal B cells and B cell non-Hodgkin's lymphomas. Semin Hematol. 1993 Oct; 30(4):318-28. PMID: 7505483.
    Citations:    Fields:    Translation:HumansCells
  139. Soiffer RJ, Roy DC, Gonin R, Murray C, Anderson KC, Freedman AS, Rabinowe SN, Robertson MJ, Spector N, Pesek K, et al. Monoclonal antibody-purged autologous bone marrow transplantation in adults with acute lymphoblastic leukemia at high risk of relapse. Bone Marrow Transplant. 1993 Sep; 12(3):243-51. PMID: 8241984.
    Citations: 2     Fields:    Translation:HumansCells
  140. Rabinowe SN, Soiffer RJ, Gribben JG, Daley H, Freedman AS, Daley J, Pesek K, Neuberg D, Pinkus G, Leavitt PR, et al. Autologous and allogeneic bone marrow transplantation for poor prognosis patients with B-cell chronic lymphocytic leukemia. Blood. 1993 Aug 15; 82(4):1366-76. PMID: 7688995.
    Citations: 16     Fields:    Translation:Humans
  141. Gribben JG, Neuberg D, Freedman AS, Gimmi CD, Pesek KW, Barber M, Saporito L, Woo SD, Coral F, Spector N, et al. Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma. Blood. 1993 Jun 15; 81(12):3449-57. PMID: 8507880.
    Citations: 26     Fields:    Translation:Humans
  142. Freedman AS, Nadler LM. Developments in purging in autotransplantation. Hematol Oncol Clin North Am. 1993 Jun; 7(3):687-715. PMID: 8344886.
    Citations:    Fields:    Translation:Humans
  143. Freedman AS, Takvorian T, Neuberg D, Mauch P, Rabinowe SN, Anderson KC, Soiffer RJ, Spector N, Grossbard M, Robertson MJ, et al. Autologous bone marrow transplantation in poor-prognosis intermediate-grade and high-grade B-cell non-Hodgkin's lymphoma in first remission: a pilot study. J Clin Oncol. 1993 May; 11(5):931-6. PMID: 8487057.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  144. Grossbard ML, Gribben JG, Freedman AS, Lambert JM, Kinsella J, Rabinowe SN, Eliseo L, Taylor JA, Blättler WA, Epstein CL, et al. Adjuvant immunotoxin therapy with anti-B4-blocked ricin after autologous bone marrow transplantation for patients with B-cell non-Hodgkin's lymphoma. Blood. 1993 May 01; 81(9):2263-71. PMID: 8481509.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  145. Rabinowe SN, Neuberg D, Bierman PJ, Vose JM, Nemunaitis J, Singer JW, Freedman AS, Mauch P, Demetri G, Onetto N, et al. Long-term follow-up of a phase III study of recombinant human granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for lymphoid malignancies. Blood. 1993 Apr 01; 81(7):1903-8. PMID: 8461475.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  146. Freedman AS, Rhynhart K, Nojima Y, Svahn J, Eliseo L, Benjamin CD, Morimoto C, Vivier E. Stimulation of protein tyrosine phosphorylation in human B cells after ligation of the beta 1 integrin VLA-4. J Immunol. 1993 Mar 01; 150(5):1645-52. PMID: 7679689.
    Citations: 13     Fields:    Translation:HumansCells
  147. Freedman AS, Munro JM, Rhynhart K, Schow P, Daley J, Lee N, Svahn J, Eliseo L, Nadler LM. Follicular dendritic cells inhibit human B-lymphocyte proliferation. Blood. 1992 Sep 01; 80(5):1284-8. PMID: 1515644.
    Citations: 1     Fields:    Translation:HumansCells
  148. Gribben JG, Saporito L, Barber M, Blake KW, Edwards RM, Griffin JD, Freedman AS, Nadler LM. Bone marrows of non-Hodgkin's lymphoma patients with a bcl-2 translocation can be purged of polymerase chain reaction-detectable lymphoma cells using monoclonal antibodies and immunomagnetic bead depletion. Blood. 1992 Aug 15; 80(4):1083-9. PMID: 1498325.
    Citations: 5     Fields:    Translation:Humans
  149. Soiffer RJ, Murray C, Mauch P, Anderson KC, Freedman AS, Rabinowe SN, Takvorian T, Robertson MJ, Spector N, Gonin R, et al. Prevention of graft-versus-host disease by selective depletion of CD6-positive T lymphocytes from donor bone marrow. J Clin Oncol. 1992 Jul; 10(7):1191-200. PMID: 1607923.
    Citations: 10     Fields:    Translation:HumansCells
  150. Robertson MJ, Soiffer RJ, Freedman AS, Rabinowe SL, Anderson KC, Ervin TJ, Murray C, Dear K, Griffin JD, Nadler LM, et al. Human bone marrow depleted of CD33-positive cells mediates delayed but durable reconstitution of hematopoiesis: clinical trial of MY9 monoclonal antibody-purged autografts for the treatment of acute myeloid leukemia. Blood. 1992 May 01; 79(9):2229-36. PMID: 1571539.
    Citations: 12     Fields:    Translation:HumansCellsCTClinical Trials
  151. Grossbard ML, Freedman AS, Ritz J, Coral F, Goldmacher VS, Eliseo L, Spector N, Dear K, Lambert JM, Blättler WA, et al. Serotherapy of B-cell neoplasms with anti-B4-blocked ricin: a phase I trial of daily bolus infusion. Blood. 1992 Feb 01; 79(3):576-85. PMID: 1370636.
    Citations: 15     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  152. Freeman GJ, Disteche CM, Gribben JG, Adler DA, Freedman AS, Dougery J, Nadler LM. The gene for B7, a costimulatory signal for T-cell activation, maps to chromosomal region 3q13.3-3q21. Blood. 1992 Jan 15; 79(2):489-94. PMID: 1370389.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  153. Freedman AS, Munro JM, Morimoto C, McIntyre BW, Rhynhart K, Lee N, Nadler LM. Follicular non-Hodgkin's lymphoma cell adhesion to normal germinal centers and neoplastic follicles involves very late antigen-4 and vascular cell adhesion molecule-1. Blood. 1992 Jan 01; 79(1):206-12. PMID: 1370204.
    Citations: 9     Fields:    Translation:HumansCells
  154. Gribben JG, Freedman As, Woo SD, Blake K, Shu RS, Freeman G, Longtine JA, Pinkus GS, Nadler LM. All advanced stage non-Hodgkin's lymphomas with a polymerase chain reaction amplifiable breakpoint of bcl-2 have residual cells containing the bcl-2 rearrangement at evaluation and after treatment. Blood. 1991 Dec 15; 78(12):3275-80. PMID: 1742487.
    Citations: 25     Fields:    Translation:HumansCells
  155. Soiffer RJ, Dear K, Rabinowe SN, Anderson KC, Freedman AS, Murray C, Tarbell NJ, Mauch P, Nadler LM, Ritz J. Hepatic dysfunction following T-cell-depleted allogeneic bone marrow transplantation. Transplantation. 1991 Dec; 52(6):1014-9. PMID: 1750063.
    Citations: 4     Fields:    Translation:HumansCells
  156. Gribben JG, Freedman AS, Neuberg D, Roy DC, Blake KW, Woo SD, Grossbard ML, Rabinowe SN, Coral F, Freeman GJ, et al. Immunologic purging of marrow assessed by PCR before autologous bone marrow transplantation for B-cell lymphoma. N Engl J Med. 1991 Nov 28; 325(22):1525-33. PMID: 1944436.
    Citations: 46     Fields:    Translation:HumansCells
  157. Freedman AS, Freeman GJ, Rhynhart K, Nadler LM. Selective induction of B7/BB-1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway. Cell Immunol. 1991 Oct 15; 137(2):429-37. PMID: 1716521.
    Citations: 66     Fields:    Translation:HumansCells
  158. Savage CO, Hughes CC, Pepinsky RB, Wallner BP, Freedman AS, Pober JS. Endothelial cell lymphocyte function-associated antigen-3 and an unidentified ligand act in concert to provide costimulation to human peripheral blood CD4+ T cells. Cell Immunol. 1991 Oct 01; 137(1):150-63. PMID: 1679377.
    Citations: 16     Fields:    Translation:HumansCells
  159. Freedman AS, Nadler LM. Immunologic markers in non-Hodgkin's lymphoma. Hematol Oncol Clin North Am. 1991 Oct; 5(5):871-89. PMID: 1938759.
    Citations: 5     Fields:    Translation:HumansCells
  160. Gimmi CD, Freeman GJ, Gribben JG, Sugita K, Freedman AS, Morimoto C, Nadler LM. B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2. Proc Natl Acad Sci U S A. 1991 Aug 01; 88(15):6575-9. PMID: 1650475.
    Citations: 120     Fields:    Translation:HumansAnimalsCells
  161. Nemunaitis J, Rabinowe SN, Singer JW, Bierman PJ, Vose JM, Freedman AS, Onetto N, Gillis S, Oette D, Gold M, et al. Recombinant granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplantation for lymphoid cancer. N Engl J Med. 1991 Jun 20; 324(25):1773-8. PMID: 1903847.
    Citations: 40     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  162. Freedman AS, Ritz J, Neuberg D, Anderson KC, Rabinowe SN, Mauch P, Takvorian T, Soiffer R, Blake K, Yeap B, et al. Autologous bone