Harvard Catalyst Profiles

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Ameya Rejeev Kirtane, Ph.D.

Other Positions

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kirtane AR, Karavasili C, Wahane A, Freitas D, Booz K, Le DTH, Hua T, Scala S, Lopes A, Hess K, Collins J, Tamang S, Ishida K, Kuosmanen JLP, Rajesh NU, Phan NV, Li J, Krogmann A, Lennerz JK, Hayward A, Langer R, Traverso G. Development of oil-based gels as versatile drug delivery systems for pediatric applications. Sci Adv. 2022 05 27; 8(21):eabm8478. PMID: 35622910; PMCID: PMC9140966.
    Citations: 1     Fields:    Translation:HumansAnimals
  2. Lee SH, Wan Q, Wentworth A, Ballinger I, Ishida K, Collins JE, Tamang S, Huang HW, Li C, Hess K, Lopes A, Kirtane AR, Lee JS, Lee S, Chen W, Wong K, Selsing G, Kim H, Buckley ST, Hayward A, Langer R, Traverso G. Implantable system for chronotherapy. Sci Adv. 2021 Nov 26; 7(48):eabj4624. PMID: 34826238; PMCID: PMC8626078.
    Citations:    Fields:    
  3. Byrne JD, Young CC, Chu JN, Pursley J, Chen MX, Wentworth AJ, Feng A, Kirtane AR, Remillard KA, Hancox CI, Bhagwat MS, Machado N, Hua T, Tamang SM, Collins JE, Ishida K, Hayward A, Becker SL, Edgington SK, Schoenfeld JD, Jeck WR, Hur C, Traverso G. Personalized Radiation Attenuating Materials for Gastrointestinal Mucosal Protection. Adv Sci (Weinh). 2021 06; 8(12):2100510. PMID: 34194950.
    Citations:    Fields:    Translation:HumansAnimalsPHPublic Health
  4. Li M, Kirtane AR, Kiyokawa J, Nagashima H, Lopes A, Tirmizi ZA, Lee CK, Traverso G, Cahill DP, Wakimoto H. Local Targeting of NAD+ Salvage Pathway Alters the Immune Tumor Microenvironment and Enhances Checkpoint Immunotherapy in Glioblastoma. Cancer Res. 2021 Apr 01; 81(7):1922. PMID: 34003791.
    Citations: 1     Fields:    
  5. Reker D, Rybakova Y, Kirtane AR, Cao R, Yang JW, Navamajiti N, Gardner A, Zhang RM, Esfandiary T, L'Heureux J, von Erlach T, Smekalova EM, Leboeuf D, Hess K, Lopes A, Rogner J, Collins J, Tamang SM, Ishida K, Chamberlain P, Yun D, Lytton-Jean A, Soule CK, Cheah JH, Hayward AM, Langer R, Traverso G. Computationally guided high-throughput design of self-assembling drug nanoparticles. Nat Nanotechnol. 2021 06; 16(6):725-733. PMID: 33767382; PMCID: PMC8197729.
    Citations: 4     Fields:    Translation:HumansAnimals
  6. Kirtane AR, Verma M, Karandikar P, Furin J, Langer R, Traverso G. Nanotechnology approaches for global infectious diseases. Nat Nanotechnol. 2021 04; 16(4):369-384. PMID: 33753915.
    Citations: 31     Fields:    Translation:Humans
  7. Li M, Kirtane AR, Kiyokawa J, Nagashima H, Lopes A, Tirmizi ZA, Lee CK, Traverso G, Cahill DP, Wakimoto H. Local Targeting of NAD+ Salvage Pathway Alters the Immune Tumor Microenvironment and Enhances Checkpoint Immunotherapy in Glioblastoma. Cancer Res. 2020 11 15; 80(22):5024-5034. PMID: 32998997.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  8. Li J, Wang T, Kirtane AR, Shi Y, Jones A, Moussa Z, Lopes A, Collins J, Tamang SM, Hess K, Shakur R, Karandikar P, Lee JS, Huang HW, Hayward A, Traverso G. Gastrointestinal synthetic epithelial linings. Sci Transl Med. 2020 08 26; 12(558). PMID: 32848090.
    Citations: 4     Fields:    Translation:Animals
  9. Reker D, Shi Y, Kirtane AR, Hess K, Zhong GJ, Crane E, Lin CH, Langer R, Traverso G. Machine Learning Uncovers Food- and Excipient-Drug Interactions. Cell Rep. 2020 03 17; 30(11):3710-3716.e4. PMID: 32187543.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  10. Kirtane AR, Hua T, Hayward A, Bajpayee A, Wahane A, Lopes A, Bensel T, Ma L, Stanczyk FZ, Brooks S, Gwynne D, Wainer J, Collins J, Tamang SM, Langer R, Traverso G. A once-a-month oral contraceptive. Sci Transl Med. 2019 12 04; 11(521). PMID: 31801885.
    Citations: 7     Fields:    Translation:AnimalsCells
  11. Khanna V, Kalscheuer S, Kirtane A, Zhang W, Panyam J. Perlecan-targeted nanoparticles for drug delivery to triple-negative breast cancer. Future Drug Discov. 2019 Jul; 1(1):FDD8. PMID: 31448368; PMCID: PMC6700713.
    Citations: 6     
  12. Liu G, Khanna V, Kirtane A, Grill A, Panyam J. Chemopreventive efficacy of oral curcumin: a prodrug hypothesis. FASEB J. 2019 08; 33(8):9453-9465. PMID: 31136203; PMCID: PMC9272759.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  13. Babaee S, Pajovic S, Kirtane AR, Shi J, Caffarel-Salvador E, Hess K, Collins JE, Tamang S, Wahane AV, Hayward AM, Mazdiyasni H, Langer R, Traverso G. Temperature-responsive biometamaterials for gastrointestinal applications. Sci Transl Med. 2019 04 17; 11(488). PMID: 30996082.
    Citations: 5     Fields:    Translation:HumansAnimals
  14. Kong YL, Zou X, McCandler CA, Kirtane AR, Ning S, Zhou J, Abid A, Jafari M, Rogner J, Minahan D, Collins JE, McDonnell S, Cleveland C, Bensel T, Tamang S, Arrick G, Gimbel A, Hua T, Ghosh U, Soares V, Wang N, Wahane A, Hayward A, Zhang S, Smith BR, Langer R, Traverso G. 3D-Printed Gastric Resident Electronics. Adv Mater Technol. 2019; 4(3):1800490. PMID: 32010758; PMCID: PMC6988123.
    Citations: 8     
  15. Altreuter DH, Kirtane AR, Grant T, Kruger C, Traverso G, Bellinger AM. Changing the pill: developments toward the promise of an ultra-long-acting gastroretentive dosage form. Expert Opin Drug Deliv. 2018 12; 15(12):1189-1198. PMID: 30392404; PMCID: PMC6396278.
    Citations: 4     Fields:    Translation:Humans
  16. Hayward A, Bensel T, Mazdiyasni H, Rogner J, Kirtane AR, Lee YL, Hua T, Bajpayee A, Collins J, McDonnell S, Cleveland C, Lopes A, Wahane A, Langer R, Traverso G. Scalable Gastric Resident Systems for Veterinary Application. Sci Rep. 2018 08 07; 8(1):11816. PMID: 30087406.
    Citations: 2     Fields:    Translation:AnimalsCells
  17. Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, Wojtkiewicz GR, Baig A, Francis JM, Rinne ML, Batten JM, Batchelor TT, Brastianos PK, Curry WT, Barker FG, Jordan JT, Iafrate AJ, Chi AS, Lennerz JK, Meyerson M, Langer R, Wakimoto H, Traverso G, Cahill DP. Genotype-targeted local therapy of glioma. Proc Natl Acad Sci U S A. 2018 09 04; 115(36):E8388-E8394. PMID: 30082399; PMCID: PMC6130372.
    Citations: 19     Fields:    Translation:HumansAnimals
  18. Traverso G, Kirtane AR, Schoellhammer CM, Langer R. Convergence for Translation: Drug-Delivery Research in Multidisciplinary Teams. Angew Chem Int Ed Engl. 2018 04 09; 57(16):4156-4163. PMID: 29520902.
    Citations: 2     Fields:    Translation:HumansAnimals
  19. Kirtane AR, Abouzid O, Minahan D, Bensel T, Hill AL, Selinger C, Bershteyn A, Craig M, Mo SS, Mazdiyasni H, Cleveland C, Rogner J, Lee YL, Booth L, Javid F, Wu SJ, Grant T, Bellinger AM, Nikolic B, Hayward A, Wood L, Eckhoff PA, Nowak MA, Langer R, Traverso G. Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy. Nat Commun. 2018 01 09; 9(1):2. PMID: 29317618; PMCID: PMC5760734.
    Citations: 38     Fields:    Translation:HumansAnimals
  20. Liu J, Pang Y, Zhang S, Cleveland C, Yin X, Booth L, Lin J, Lucy Lee YA, Mazdiyasni H, Saxton S, Kirtane AR, Erlach TV, Rogner J, Langer R, Traverso G. Triggerable tough hydrogels for gastric resident dosage forms. Nat Commun. 2017 07 25; 8(1):124. PMID: 28743858.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  21. Song JM, Molla K, Anandharaj A, Cornax I, O Sullivan MG, Kirtane AR, Panyam J, Kassie F. Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling. Oncotarget. 2017 Apr 18; 8(16):26927-26940. PMID: 28460475.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  22. Kirtane AR, Rothenberger MK, Frieberg A, Nephew K, Schultz-Darken N, Schmidt T, Reimann T, Haase AT, Panyam J. Evaluation of Vaginal Drug Levels and Safety of a Locally Administered Glycerol Monolaurate Cream in Rhesus Macaques. J Pharm Sci. 2017 07; 106(7):1821-1827. PMID: 28389267.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  23. Kirtane AR, Sadhukha T, Kim H, Khanna V, Koniar B, Panyam J. Fibrinolytic Enzyme Cotherapy Improves Tumor Perfusion and Therapeutic Efficacy of Anticancer Nanomedicine. Cancer Res. 2017 03 15; 77(6):1465-1475. PMID: 28108516; PMCID: PMC5523511.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  24. Siegel RA, Kirtane AR, Panyam J. Assessing the Benefits of Drug Delivery by Nanocarriers: A Partico/Pharmacokinetic Framework. IEEE Trans Biomed Eng. 2017 09; 64(9):2176-2185. PMID: 27913319.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  25. Kirtane AR, Langer R, Traverso G. Past, Present, and Future Drug Delivery Systems for Antiretrovirals. J Pharm Sci. 2016 12; 105(12):3471-3482. PMID: 27771050.
    Citations: 11     Fields:    Translation:HumansAnimals
  26. Song JM, Anandharaj A, Upadhyaya P, Kirtane AR, Kim JH, Hong KH, Panyam J, Kassie F. Honokiol suppresses lung tumorigenesis by targeting EGFR and its downstream effectors. Oncotarget. 2016 Sep 06; 7(36):57752-57769. PMID: 27458163.
    Citations: 11     Fields:    Translation:Animals
  27. Kirtane AR, Wong HL, Guru BR, Lis LG, Georg GI, Gurvich VJ, Panyam J. Reformulating Tylocrebrine in Epidermal Growth Factor Receptor Targeted Polymeric Nanoparticles Improves Its Therapeutic Index. Mol Pharm. 2015 Aug 03; 12(8):2912-23. PMID: 26065924; PMCID: PMC4525301.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  28. Kirtane AR, Siegel RA, Panyam J. A pharmacokinetic model for quantifying the effect of vascular permeability on the choice of drug carrier: a framework for personalized nanomedicine. J Pharm Sci. 2015 Mar; 104(3):1174-86. PMID: 25583443.
    Citations: 5     Fields:    Translation:HumansAnimals
  29. Song JM, Kirtane AR, Upadhyaya P, Qian X, Balbo S, Teferi F, Panyam J, Kassie F. Intranasal delivery of liposomal indole-3-carbinol improves its pulmonary bioavailability. Int J Pharm. 2014 Dec 30; 477(1-2):96-101. PMID: 25311179.
    Citations: 2     Fields:    Translation:Animals
  30. Usacheva M, Swaminathan SK, Kirtane AR, Panyam J. Enhanced photodynamic therapy and effective elimination of cancer stem cells using surfactant-polymer nanoparticles. Mol Pharm. 2014 Sep 02; 11(9):3186-95. PMID: 25061685.
    Citations: 16     Fields:    Translation:HumansCells
  31. Arora S, Swaminathan SK, Kirtane A, Srivastava SK, Bhardwaj A, Singh S, Panyam J, Singh AP. Synthesis, characterization, and evaluation of poly (D,L-lactide-co-glycolide)-based nanoformulation of miRNA-150: potential implications for pancreatic cancer therapy. Int J Nanomedicine. 2014; 9:2933-42. PMID: 24971005.
    Citations: 37     Fields:    Translation:HumansCells
  32. Kirtane AR, Panyam J. Polymer nanoparticles: Weighing up gene delivery. Nat Nanotechnol. 2013 Nov; 8(11):805-6. PMID: 24202534.
    Citations: 19     Fields:    Translation:HumansAnimals
  33. Kirtane AR, Kalscheuer SM, Panyam J. Exploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunities. Adv Drug Deliv Rev. 2013 Nov; 65(13-14):1731-47. PMID: 24036273.
    Citations: 49     Fields:    Translation:HumansAnimals
  34. Roger E, Kalscheuer S, Kirtane A, Guru BR, Grill AE, Whittum-Hudson J, Panyam J. Folic acid functionalized nanoparticles for enhanced oral drug delivery. Mol Pharm. 2012 Jul 02; 9(7):2103-10. PMID: 22670575.
    Citations: 36     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.