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Peter Dornbos, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Dornbos P, Koesterer R, Ruttenburg A, Nguyen T, Cole JB, Leong A, Meigs JB, Florez JC, Rotter JI, Udler MS, Flannick J. A combined polygenic score of 21,293 rare and 22 common variants improves diabetes diagnosis based on hemoglobin A1C levels. Nat Genet. 2022 Nov; 54(11):1609-1614. PMID: 36280733.
    Citations:    Fields:    Translation:Humans
  2. Deaton AM, Dubey A, Ward LD, Dornbos P, Flannick J, Yee E, Ticau S, Noetzli L, Parker MM, Hoffing RA, Willis C, Plekan ME, Holleman AM, Hinkle G, Fitzgerald K, Vaishnaw AK, Nioi P. Rare loss of function variants in the hepatokine gene INHBE protect from abdominal obesity. Nat Commun. 2022 07 27; 13(1):4319. PMID: 35896531; PMCID: PMC9329324.
    Citations:    Fields:    Translation:Humans
  3. Dornbos P, Singh P, Jang DK, Mahajan A, Biddinger SB, Rotter JI, McCarthy MI, Flannick J. Evaluating human genetic support for hypothesized metabolic disease genes. Cell Metab. 2022 05 03; 34(5):661-666. PMID: 35421386; PMCID: PMC9166611.
    Citations:    Fields:    Translation:Humans
  4. Hindy G, Dornbos P, Chaffin MD, Liu DJ, Wang M, Selvaraj MS, Zhang D, Park J, Aguilar-Salinas CA, Antonacci-Fulton L, Ardissino D, Arnett DK, Aslibekyan S, Atzmon G, Ballantyne CM, Barajas-Olmos F, Barzilai N, Becker LC, Bielak LF, Bis JC, Blangero J, Boerwinkle E, Bonnycastle LL, Bottinger E, Bowden DW, Bown MJ, Brody JA, Broome JG, Burtt NP, Cade BE, Centeno-Cruz F, Chan E, Chang YC, Chen YI, Cheng CY, Choi WJ, Chowdhury R, Contreras-Cubas C, Córdova EJ, Correa A, Cupples LA, Curran JE, Danesh J, de Vries PS, DeFronzo RA, Doddapaneni H, Duggirala R, Dutcher SK, Ellinor PT, Emery LS, Florez JC, Fornage M, Freedman BI, Fuster V, Garay-Sevilla ME, García-Ortiz H, Germer S, Gibbs RA, Gieger C, Glaser B, Gonzalez C, Gonzalez-Villalpando ME, Graff M, Graham SE, Grarup N, Groop LC, Guo X, Gupta N, Han S, Hanis CL, Hansen T, He J, Heard-Costa NL, Hung YJ, Hwang MY, Irvin MR, Islas-Andrade S, Jarvik GP, Kang HM, Kardia SLR, Kelly T, Kenny EE, Khan AT, Kim BJ, Kim RW, Kim YJ, Koistinen HA, Kooperberg C, Kuusisto J, Kwak SH, Laakso M, Lange LA, Lee J, Lee J, Lee S, Lehman DM, Lemaitre RN, Linneberg A, Liu J, Loos RJF, Lubitz SA, Lyssenko V, Ma RCW, Martin LW, Martínez-Hernández A, Mathias RA, McGarvey ST, McPherson R, Meigs JB, Meitinger T, Melander O, Mendoza-Caamal E, Metcalf GA, Mi X, Mohlke KL, Montasser ME, Moon JY, Moreno-Macías H, Morrison AC, Muzny DM, Nelson SC, Nilsson PM, O'Connell JR, Orho-Melander M, Orozco L, Palmer CNA, Palmer ND, Park CJ, Park KS, Pedersen O, Peralta JM, Peyser PA, Post WS, Preuss M, Psaty BM, Qi Q, Rao DC, Redline S, Reiner AP, Revilla-Monsalve C, Rich SS, Samani N, Schunkert H, Schurmann C, Seo D, Seo JS, Sim X, Sladek R, Small KS, So WY, Stilp AM, Tai ES, Tam CHT, Taylor KD, Teo YY, Thameem F, Tomlinson B, Tsai MY, Tuomi T, Tuomilehto J, Tusié-Luna T, Udler MS, van Dam RM, Vasan RS, Viaud Martinez KA, Wang FF, Wang X, Watkins H, Weeks DE, Wilson JG, Witte DR, Wong TY, Yanek LR, Kathiresan S, Rader DJ, Rotter JI, Boehnke M, McCarthy MI, Willer CJ, Natarajan P, Flannick JA, Khera AV, Peloso GM. Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes. Am J Hum Genet. 2022 01 06; 109(1):81-96. PMID: 34932938; PMCID: PMC8764201.
    Citations: 1     Fields:    Translation:Humans
  5. Goodrich JK, Singer-Berk M, Son R, Sveden A, Wood J, England E, Cole JB, Weisburd B, Watts N, Caulkins L, Dornbos P, Koesterer R, Zappala Z, Zhang H, Maloney KA, Dahl A, Aguilar-Salinas CA, Atzmon G, Barajas-Olmos F, Barzilai N, Blangero J, Boerwinkle E, Bonnycastle LL, Bottinger E, Bowden DW, Centeno-Cruz F, Chambers JC, Chami N, Chan E, Chan J, Cheng CY, Cho YS, Contreras-Cubas C, Córdova E, Correa A, DeFronzo RA, Duggirala R, Dupuis J, Garay-Sevilla ME, García-Ortiz H, Gieger C, Glaser B, González-Villalpando C, Gonzalez ME, Grarup N, Groop L, Gross M, Haiman C, Han S, Hanis CL, Hansen T, Heard-Costa NL, Henderson BE, Hernandez JMM, Hwang MY, Islas-Andrade S, Jørgensen ME, Kang HM, Kim BJ, Kim YJ, Koistinen HA, Kooner JS, Kuusisto J, Kwak SH, Laakso M, Lange L, Lee JY, Lee J, Lehman DM, Linneberg A, Liu J, Loos RJF, Lyssenko V, Ma RCW, Martínez-Hernández A, Meigs JB, Meitinger T, Mendoza-Caamal E, Mohlke KL, Morris AD, Morrison AC, Ng MCY, Nilsson PM, O'Donnell CJ, Orozco L, Palmer CNA, Park KS, Post WS, Pedersen O, Preuss M, Psaty BM, Reiner AP, Revilla-Monsalve C, Rich SS, Rotter JI, Saleheen D, Schurmann C, Sim X, Sladek R, Small KS, So WY, Spector TD, Strauch K, Strom TM, Tai ES, Tam CHT, Teo YY, Thameem F, Tomlinson B, Tracy RP, Tuomi T, Tuomilehto J, Tusié-Luna T, van Dam RM, Vasan RS, Wilson JG, Witte DR, Wong TY, Burtt NP, Zaitlen N, McCarthy MI, Boehnke M, Pollin TI, Flannick J, Mercader JM, O'Donnell-Luria A, Baxter S, Florez JC, MacArthur DG, Udler MS. Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. Nat Commun. 2021 06 09; 12(1):3505. PMID: 34108472; PMCID: PMC8190084.
    Citations: 10     Fields:    Translation:Humans
  6. Jurgelewicz A, Dornbos P, Warren M, Nault R, Arkatkar A, Lin H, Threadgill DW, Zacharewski T, LaPres JJ. Genetics-Based Approach to Identify Novel Genes Regulated by the Aryl Hydrocarbon Receptor in Mouse Liver. Toxicol Sci. 2021 05 27; 181(2):285-294. PMID: 33720361.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  7. Warren MR, Radulescu A, Dornbos P, Cuomo D, Zumwalt S, Bueso-Mendoza D, Nitcher M, LaPres JJ, Threadgill DW. Peanut butter as an alternative dose delivery method to prevent strain-dependent orogastric gavage-induced stress in mouse teratogenicity studies. J Pharmacol Toxicol Methods. 2021 Jan-Feb; 107:106948. PMID: 33387613; PMCID: PMC9059485.
    Citations:    Fields:    Translation:Animals
  8. Dornbos P, Arkatkar AA, LaPres JJ. An Automated Method To Predict Mouse Gene and Protein Sequences Using Variant Data. G3 (Bethesda). 2020 03 05; 10(3):925-932. PMID: 31911484.
    Citations: 1     Fields:    Translation:AnimalsCells
  9. Dornbos P, Jurgelewicz A, Fader KA, Williams K, Zacharewski TR, LaPres JJ. Characterizing the Role of HMG-CoA Reductase in Aryl Hydrocarbon Receptor-Mediated Liver Injury in C57BL/6 Mice. Sci Rep. 2019 11 01; 9(1):15828. PMID: 31676775.
    Citations: 1     Fields:    Translation:Animals
  10. Dornbos P, Warren M, Crawford RB, Kaminski NE, Threadgill DW, LaPres JJ. Characterizing Serpinb2 as a Modulator of TCDD-Induced Suppression of the B Cell. Chem Res Toxicol. 2018 11 19; 31(11):1248-1259. PMID: 30339366; PMCID: PMC7234800.
    Citations: 3     Fields:    Translation:AnimalsCells
  11. Dornbos P, LaPres JJ. Incorporating population-level genetic variability within laboratory models in toxicology: From the individual to the population. Toxicology. 2018 02 15; 395:1-8. PMID: 29275117.
    Citations: 9     Fields:    Translation:HumansAnimals
  12. Arini A, Mittal K, Dornbos P, Head J, Rutkiewicz J, Basu N. A cell-free testing platform to screen chemicals of potential neurotoxic concern across twenty vertebrate species. Environ Toxicol Chem. 2017 11; 36(11):3081-3090. PMID: 28594109.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  13. Nault R, Fader KA, Ammendolia DA, Dornbos P, Potter D, Sharratt B, Kumagai K, Harkema JR, Lunt SY, Matthews J, Zacharewski T. Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fibrosis. Toxicol Sci. 2016 12; 154(2):253-266. PMID: 27562557; PMCID: PMC5139066.
    Citations: 28     Fields:    Translation:AnimalsCells
  14. Dornbos P, Crawford RB, Kaminski NE, Hession SL, LaPres JJ. The Influence of Human Interindividual Variability on the Low-Dose Region of Dose-Response Curve Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Primary B Cells. Toxicol Sci. 2016 10; 153(2):352-60. PMID: 27473338; PMCID: PMC5036619.
    Citations: 11     Fields:    Translation:HumansCells
  15. Hwang HJ, Dornbos P, LaPres JJ. Data on AHR-dependent changes in the mitochondrial proteome in response to ,3,7,8-tetrachlorodibenzo-p-dioxin. Data Brief. 2016 Sep; 8:191-5. PMID: 27331086; PMCID: PMC4898910.
    Citations: 2     
  16. Hwang HJ, Dornbos P, Steidemann M, Dunivin TK, Rizzo M, LaPres JJ. Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome. Toxicol Appl Pharmacol. 2016 08 01; 304:121-32. PMID: 27105554; PMCID: PMC4930739.
    Citations: 22     Fields:    Translation:AnimalsCells
  17. Saini Y, Proper SP, Dornbos P, Greenwood KK, Kopec AK, Lynn SG, Grier E, Burgoon LD, Zacharewski TR, Thomas RS, Harkema JR, LaPres JJ. Loss of Hif-2a Rescues the Hif-1a Deletion Phenotype of Neonatal Respiratory Distress In Mice. PLoS One. 2015; 10(9):e0139270. PMID: 26422241.
    Citations: 3     Fields:    Translation:AnimalsCells
  18. Dornbos P, Chernyak S, Rutkiewicz J, Cooley T, Strom S, Batterman S, Basu N. Hepatic polybrominated diphenyl ether (PBDE) levels in Wisconsin river otters (Lontra canadensis) and Michigan bald eagles (Haliaeetus leucocephalus). J Great Lakes Res. 2015 Mar; 41(1):222-227. PMID: 25745277; PMCID: PMC4347902.
    Citations: 2     
  19. Dornbos P, Strom S, Basu N. Mercury exposure and neurochemical biomarkers in multiple brain regions of Wisconsin river otters (Lontra canadensis). Ecotoxicology. 2013 Apr; 22(3):469-75. PMID: 23340980.
    Citations: 3     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.