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Carlos Simon, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Simon C. Introduction: How evident is the evidence? Fertil Steril. 2020 Jun; 113(6):1091-1092. PMID: 32482243.
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  2. Girardi L, Serdarogullari M, Patassini C, Poli M, Fabiani M, Caroselli S, Coban O, Findikli N, Boynukalin FK, Bahceci M, Chopra R, Canipari R, Cimadomo D, Rienzi L, Ubaldi F, Hoffmann E, Rubio C, Simon C, Capalbo A. Incidence, Origin, and Predictive Model for the Detection and Clinical Management of Segmental Aneuploidies in Human Embryos. Am J Hum Genet. 2020 04 02; 106(4):525-534. PMID: 32220293.
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  3. Roque M, Simon C. Time to pregnancy: as important for patients as underestimated by doctors. Fertil Steril. 2020 Mar; 113(3):522-523. PMID: 32111473.
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  4. Simon C. Operative hysteroscopy should be repeated as many times as necessary for the treatment of refractory Asherman syndrome versus is there any alternative therapy worth considering? Fertil Steril. 2020 Mar; 113(3):510. PMID: 32089254.
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  5. Simon C, Sakkas D, Gardner D, Critchley H. Precision medicine in human reproduction. Special Issue. Biol Reprod. 2019 12 24; 101(6):1075. PMID: 31616936.
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  6. Garcia-Grau I, Simon C, Moreno I. Uterine microbiome-low biomass and high expectations†. Biol Reprod. 2019 12 24; 101(6):1102-1114. PMID: 30544156.
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  7. Garrido-Gomez T, Quiñonero A, Dominguez F, Rubert L, Perales A, Hajjar KA, Simon C. Preeclampsia: a defect in decidualization is associated with deficiency of Annexin A2. Am J Obstet Gynecol. 2020 04; 222(4):376.e1-376.e17. PMID: 31738896.
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  8. Garcia-Grau I, Perez-Villaroya D, Bau D, Gonzalez-Monfort M, Vilella F, Moreno I, Simon C. Taxonomical and Functional Assessment of the Endometrial Microbiota in A Context of Recurrent Reproductive Failure: A Case Report. Pathogens. 2019 Oct 24; 8(4). PMID: 31653041.
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  9. Niederberger C, Pellicer A, Simon C. Happy Birthday to ASRM from Fertility and Sterility. Fertil Steril. 2019 10; 112(4 Suppl1):e1. PMID: 31623722.
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  10. Simon C. Introduction: Preconceptional care: do we have to care? Fertil Steril. 2019 10; 112(4):611-612. PMID: 31561862.
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  11. Niederberger C, Pellicer A, Simon C, Kathrins M, Goldstein M, Sigman M, Schlegel PN, Munné S, Gardner DK, Cobo A, Coutifaris C, Donnez J, Taylor HS, Giudice LC, Fauser BCJM, Lindheim SR, Rosenwaks Z, Casper RF, de Ziegler D, Gibbons WE, Paulson RJ, Laufer N, Klock SC, Mendola P, Sauer MV. 25 historic papers: an ASRM 75th birthday gift from Fertility and Sterility. Fertil Steril. 2019 10; 112(4 Suppl1):e2-e27. PMID: 31623734.
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  12. Carrasquillo RJ, Kohn TP, Cinnioglu C, Rubio C, Simon C, Ramasamy R, Al-Asmar N. Advanced paternal age does not affect embryo aneuploidy following blastocyst biopsy in egg donor cycles. J Assist Reprod Genet. 2019 Oct; 36(10):2039-2045. PMID: 31385121.
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  13. Bulletti C, Simon C. Bioengineered uterus: a path toward ectogenesis. Fertil Steril. 2019 09; 112(3):446-447. PMID: 31371052.
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  14. Simon C, Romero R. Preconceptional care, where reproductive medicine meets obstetrics: the origins of lifetime health. Fertil Steril. 2019 04; 111(4):657-658. PMID: 30929724.
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  15. Moreno I, Simon C. An endometrial pathology in the inflammation cloud that can be accessed with a microbial app. Fertil Steril. 2019 04; 111(4):679-680. PMID: 30871763.
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  16. Santamaria X, Mas A, Cervelló I, Taylor HS, Simon C. Reply: Bone marrow-derived endometrial cells: what you see is what you get. Hum Reprod Update. 2019 03 01; 25(2):274-275. PMID: 30601981.
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  17. Simon C. To what extent is the testing of the reproductive risk of a couple aiming to conceive meaningful in the contemporary clinical context? Fertil Steril. 2019 02; 111(2):227-228. PMID: 30642572.
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  18. Capalbo A, Chokoshvili D, Dugoff L, Franasiak J, Gleicher N, Pennings G, Simon C. Should the reproductive risk of a couple aiming to conceive be tested in the contemporary clinical context? Fertil Steril. 2019 02; 111(2):229-238. PMID: 30642571.
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  19. Moreno I, Simon C. Deciphering the effect of reproductive tract microbiota on human reproduction. Reprod Med Biol. 2019 Jan; 18(1):40-50. PMID: 30655720.
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  20. Santamaria X, Mas A, Cervelló I, Taylor H, Simon C. Uterine stem cells: from basic research to advanced cell therapies. Hum Reprod Update. 2018 11 01; 24(6):673-693. PMID: 30239705.
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  21. Moreno I, Simon C. Relevance of assessing the uterine microbiota in infertility. Fertil Steril. 2018 08; 110(3):337-343. PMID: 30098680.
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  22. Simon C. Introduction: Do microbes in the female reproductive function matter? Fertil Steril. 2018 08; 110(3):325-326. PMID: 30037698.
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  23. Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, Paulson RJ, Goldfarb JM, Brännström M, Donnez J, Silber S, Dolmans MM, Simpson JL, Handyside AH, Munné S, Eguizabal C, Montserrat N, Izpisua Belmonte JC, Trounson A, Simon C, Tulandi T, Giudice LC, Norman RJ, Hsueh AJ, Sun Y, Laufer N, Kochman R, Eldar-Geva T, Lunenfeld B, Ezcurra D, D'Hooghe T, Fauser BCJM, Tarlatzis BC, Meldrum DR, Casper RF, Fatemi HM, Devroey P, Galliano D, Wikland M, Sigman M, Schoor RA, Goldstein M, Lipshultz LI, Schlegel PN, Hussein A, Oates RD, Brannigan RE, Ross HE, Pennings G, Klock SC, Brown S, Van Steirteghem A, Rebar RW, LaBarbera AR. Forty years of IVF. Fertil Steril. 2018 07 15; 110(2):185-324.e5. PMID: 30053940.
    Citations:    Fields:    Translation:Humans
  24. Simon C, Greening DW, Bolumar D, Balaguer N, Salamonsen LA, Vilella F. Extracellular Vesicles in Human Reproduction in Health and Disease. Endocr Rev. 2018 06 01; 39(3):292-332. PMID: 29390102.
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  25. Milan M, Mateu E, Blesa D, Clemente-Ciscar M, Simon C. Fetal sex determination in twin pregnancies using cell free fetal DNA analysis. Prenat Diagn. 2018 Apr 23. PMID: 29683524.
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  26. Moreno I, Cicinelli E, Garcia-Grau I, Gonzalez-Monfort M, Bau D, Vilella F, De Ziegler D, Resta L, Valbuena D, Simon C. The diagnosis of chronic endometritis in infertile asymptomatic women: a comparative study of histology, microbial cultures, hysteroscopy, and molecular microbiology. Am J Obstet Gynecol. 2018 06; 218(6):602.e1-602.e16. PMID: 29477653.
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  27. Valdes CT, Schutt A, Simon C. Implantation failure of endometrial origin: it is not pathology, but our failure to synchronize the developing embryo with a receptive endometrium. Fertil Steril. 2017 07; 108(1):15-18. PMID: 28668151.
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  28. Valbuena D, Valdes CT, Simon C. Introduction: Endometrial function: facts, urban legends, and an eye to the future. Fertil Steril. 2017 07; 108(1):4-8. PMID: 28601409.
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  29. Simon C. Introduction: To transfer or not transfer…a mosaic embryo, that is the question. Fertil Steril. 2017 05; 107(5):1083-1084. PMID: 28433365.
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  30. Simon C. Why should patients experience infertility or poor outcomes before using assisted reproductive technologies? Fertil Steril. 2017 04; 107(4):878-879. PMID: 28366414.
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  31. Comstock IA, Diaz-Gimeno P, Cabanillas S, Bellver J, Sebastian-Leon P, Shah M, Schutt A, Valdes CT, Ruiz-Alonso M, Valbuena D, Simon C, Lathi RB. Does an increased body mass index affect endometrial gene expression patterns in infertile patients? A functional genomics analysis. Fertil Steril. 2017 Mar; 107(3):740-748.e2. PMID: 27919438.
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  32. Moreno I, Codoñer FM, Vilella F, Valbuena D, Martinez-Blanch JF, Jimenez-Almazán J, Alonso R, Alamá P, Remohí J, Pellicer A, Ramon D, Simon C. Evidence that the endometrial microbiota has an effect on implantation success or failure. Am J Obstet Gynecol. 2016 Dec; 215(6):684-703. PMID: 27717732.
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  33. Medrano JV, Rombaut C, Simon C, Pellicer A, Goossens E. Human spermatogonial stem cells display limited proliferation in vitro under mouse spermatogonial stem cell culture conditions. Fertil Steril. 2016 Nov; 106(6):1539-1549.e8. PMID: 27490045.
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  34. Sermon K, Capalbo A, Cohen J, Coonen E, De Rycke M, De Vos A, Delhanty J, Fiorentino F, Gleicher N, Griesinger G, Grifo J, Handyside A, Harper J, Kokkali G, Mastenbroek S, Meldrum D, Meseguer M, Montag M, Munné S, Rienzi L, Rubio C, Scott K, Scott R, Simon C, Swain J, Treff N, Ubaldi F, Vassena R, Vermeesch JR, Verpoest W, Wells D, Geraedts J. The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists. Mol Hum Reprod. 2016 08; 22(8):845-57. PMID: 27256483.
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  35. Meldrum DR, Casper RF, Diez-Juan A, Simon C, Domar AD, Frydman R. Aging and the environment affect gamete and embryo potential: can we intervene? Fertil Steril. 2016 Mar; 105(3):548-559. PMID: 26812244.
    Citations: 8     Fields:    Translation:AnimalsCells
  36. Simon C, Sakkas D, Gardner DK, Critchley HO. Biomarkers in reproductive medicine: the quest for new answers. Hum Reprod Update. 2015 Nov-Dec; 21(6):695-7. PMID: 26386470.
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  37. Martin J, Yi Y, Alberola T, Rodríguez-Iglesias B, Jiménez-Almazán J, Li Q, Du H, Alama P, Ruiz A, Bosch E, Garrido N, Simon C. Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology. Fertil Steril. 2015 Nov; 104(5):1286-93. PMID: 26354092.
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  38. Vera-Rodriguez M, Chavez SL, Rubio C, Reijo Pera RA, Simon C. Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis. Nat Commun. 2015 Jul 07; 6:7601. PMID: 26151134.
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  39. Miravet-Valenciano JA, Rincon-Bertolin A, Vilella F, Simon C. Understanding and improving endometrial receptivity. Curr Opin Obstet Gynecol. 2015 Jun; 27(3):187-92. PMID: 25827647.
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  40. Aleixandre-Benavent R, Simon C, Fauser BC. Trends in clinical reproductive medicine research: 10 years of growth. Fertil Steril. 2015 Jul; 104(1):131-7.e5. PMID: 25936232.
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  41. Thouas GA, Dominguez F, Green MP, Vilella F, Simon C, Gardner DK. Soluble ligands and their receptors in human embryo development and implantation. Endocr Rev. 2015 Feb; 36(1):92-130. PMID: 25548832.
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  42. Medrano JV, Simon C, Pera RR. Human germ cell differentiation from pluripotent embryonic stem cells and induced pluripotent stem cells. Methods Mol Biol. 2014; 1154:563-78. PMID: 24782029.
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  43. Galan A, Diaz-Gimeno P, Poo ME, Valbuena D, Sanchez E, Ruiz V, Dopazo J, Montaner D, Conesa A, Simon C. Defining the genomic signature of totipotency and pluripotency during early human development. PLoS One. 2013; 8(4):e62135. PMID: 23614026.
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  44. Paule S, Aljofan M, Simon C, Rombauts LJ, Nie G. Cleavage of endometrial a-integrins into their functional forms is mediated by proprotein convertase 5/6. Hum Reprod. 2012 Sep; 27(9):2766-74. PMID: 22740495.
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  45. Garrido-Gómez T, Dominguez F, Quiñonero A, Estella C, Vilella F, Pellicer A, Simon C. Annexin A2 is critical for embryo adhesiveness to the human endometrium by RhoA activation through F-actin regulation. FASEB J. 2012 Sep; 26(9):3715-27. PMID: 22645245.
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  46. Ensenat-Waser R, Pellicer A, Simon C. Reprogrammed induced pluripotent stem cells: how suitable could they be in reproductive medicine? Fertil Steril. 2009 Apr; 91(4):971-4. PMID: 19200985.
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  47. Busso CE, Melo MA, Fernandez M, Pellicer A, Simon C. Implantation in IVF. Int Surg. 2006 Sep-Oct; 91(5 Suppl):S63-76. PMID: 17436606.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.