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Carlos Simon, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Díaz-García C, Herraiz S, Pamplona L, Subirá J, Soriano MJ, Simon C, Seli E, Pellicer A. Follicular activation in women previously diagnosed with poor ovarian response: a randomized, controlled trial. Fertil Steril. 2022 04; 117(4):747-755. PMID: 35367015.
    Citations:    Fields:    Translation:Humans
  2. Machado-Lopez A, Alonso R, Lago V, Jimenez-Almazan J, Garcia M, Monleon J, Lopez S, Barcelo F, Torroba A, Ortiz S, Domingo S, Simon C, Mas A. Integrative Genomic and Transcriptomic Profiling Reveals a Differential Molecular Signature in Uterine Leiomyoma versus Leiomyosarcoma. Int J Mol Sci. 2022 Feb 16; 23(4). PMID: 35216305; PMCID: PMC8877247.
    Citations: 1     Fields:    Translation:HumansCells
  3. Moreno I, Garcia-Grau I, Perez-Villaroya D, Gonzalez-Monfort M, Bahçeci M, Barrionuevo MJ, Taguchi S, Puente E, Dimattina M, Lim MW, Meneghini G, Aubuchon M, Leondires M, Izquierdo A, Perez-Olgiati M, Chavez A, Seethram K, Bau D, Gomez C, Valbuena D, Vilella F, Simon C. Endometrial microbiota composition is associated with reproductive outcome in infertile patients. Microbiome. 2022 01 04; 10(1):1. PMID: 34980280; PMCID: PMC8725275.
    Citations: 5     Fields:    Translation:Humans
  4. Toson B, Simon C, Moreno I. The Endometrial Microbiome and Its Impact on Human Conception. Int J Mol Sci. 2022 Jan 01; 23(1). PMID: 35008911; PMCID: PMC8745284.
    Citations: 3     Fields:    Translation:Humans
  5. Garrido-Gomez T, Castillo-Marco N, Clemente-Ciscar M, Cordero T, Muñoz-Blat I, Amadoz A, Jimenez-Almazan J, Monfort-Ortiz R, Climent R, Perales-Marin A, Simon C. Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia. Elife. 2021 10 28; 10. PMID: 34709177.
    Citations: 3     Fields:    Translation:HumansCells
  6. Simon C, Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L. In vitro fertilization and andrology laboratories in 2030. Fertil Steril. 2021 07; 116(1):2-3. PMID: 34148585.
    Citations:    Fields:    Translation:Humans
  7. Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L, Simon C. In vitro fertilization and andrology laboratory in 2030: expert visions. Fertil Steril. 2021 07; 116(1):4-12. PMID: 34148588.
    Citations:    Fields:    Translation:Humans
  8. Simon C. Consensus vision. Fertil Steril. 2021 07; 116(1):13-14. PMID: 34148581.
    Citations:    Fields:    Translation:Humans
  9. Vilella F, Wang W, Moreno I, Quake SR, Simon C. Understanding the human endometrium in the 21st century. Am J Obstet Gynecol. 2021 07; 225(1):1-2. PMID: 34023092.
    Citations:    Fields:    Translation:Humans
  10. Ruiz-Alonso M, Valbuena D, Gomez C, Cuzzi J, Simon C. Endometrial Receptivity Analysis (ERA): data versus opinions. Hum Reprod Open. 2021; 2021(2):hoab011. PMID: 33880420.
    Citations: 4     
  11. Rubio C, Racowsky C, Barad DH, Scott RT, Simon C. Noninvasive preimplantation genetic testing for aneuploidy in spent culture medium as a substitute for trophectoderm biopsy. Fertil Steril. 2021 04; 115(4):841-849. PMID: 33741125.
    Citations: 1     Fields:    Translation:Humans
  12. Simon C. Noninvasive preimplantation genetic testing for aneuploidy in spent blastocyst media will substitute for trophectoderm biopsy. Fertil Steril. 2021 04; 115(4):840. PMID: 33726897.
    Citations: 1     Fields:    Translation:Humans
  13. Foulk R, Sakkas D, Kayali R, Valbuena D, Simon C, Cuzzi J. Severe acute respiratory syndrome coronavirus 2 immunity: infective and naive incidence in fertility clinics after lockdown. Am J Obstet Gynecol. 2021 07; 225(1):103-105. PMID: 33716073; PMCID: PMC7952128.
    Citations:    Fields:    Translation:HumansPHPublic Health
  14. O'Brien JE, Adashi EY, Simon C. Darwin meets Mendel in the reproductive medicine field: Homo sapiens 2.0 is inevitable. Fertil Steril. 2021 04; 115(4):850-851. PMID: 33642062.
    Citations:    Fields:    Translation:Humans
  15. Vilella F, Simon C. Reproductive medicine, as seen through single-cell glasses. Fertil Steril. 2021 02; 115(2):296-297. PMID: 33386110.
    Citations:    Fields:    Translation:Humans
  16. Capalbo A, Rubio C, Simon C. Testing the mathematical model for PGT-A inefficiency with scientific sources demonstrates the efficacy of PGT-A. Hum Reprod. 2020 09 01; 35(9):2163-2165. PMID: 32766771.
    Citations: 1     Fields:    Translation:Humans
  17. Simon C. Introduction: How evident is the evidence? Fertil Steril. 2020 Jul 02. PMID: 32624212.
    Citations:    Fields:    
  18. Simon C. Introduction: How evident is the evidence? Fertil Steril. 2020 06; 113(6):1091-1092. PMID: 32482243.
    Citations: 1     Fields:    Translation:Humans
  19. Girardi L, Serdarogullari M, Patassini C, Poli M, Fabiani M, Caroselli S, Coban O, Findikli N, Boynukalin FK, Bahceci M, Chopra R, Canipari R, Cimadomo D, Rienzi L, Ubaldi F, Hoffmann E, Rubio C, Simon C, Capalbo A. Incidence, Origin, and Predictive Model for the Detection and Clinical Management of Segmental Aneuploidies in Human Embryos. Am J Hum Genet. 2020 04 02; 106(4):525-534. PMID: 32220293.
    Citations: 20     Fields:    Translation:HumansCells
  20. Roque M, Simon C. Time to pregnancy: as important for patients as underestimated by doctors. Fertil Steril. 2020 03; 113(3):522-523. PMID: 32111473.
    Citations: 1     Fields:    Translation:Humans
  21. Simon C. Operative hysteroscopy should be repeated as many times as necessary for the treatment of refractory Asherman syndrome versus is there any alternative therapy worth considering? Fertil Steril. 2020 03; 113(3):510. PMID: 32089254.
    Citations:    Fields:    Translation:Humans
  22. Simon C, Sakkas D, Gardner D, Critchley H. Precision medicine in human reproduction. Special Issue. Biol Reprod. 2019 12 24; 101(6):1075. PMID: 31616936.
    Citations: 3     Fields:    Translation:Humans
  23. Garcia-Grau I, Simon C, Moreno I. Uterine microbiome-low biomass and high expectations†. Biol Reprod. 2019 12 24; 101(6):1102-1114. PMID: 30544156.
    Citations: 8     Fields:    Translation:Humans
  24. Garrido-Gomez T, Quiñonero A, Dominguez F, Rubert L, Perales A, Hajjar KA, Simon C. Preeclampsia: a defect in decidualization is associated with deficiency of Annexin A2. Am J Obstet Gynecol. 2020 04; 222(4):376.e1-376.e17. PMID: 31738896.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  25. Garcia-Grau I, Perez-Villaroya D, Bau D, Gonzalez-Monfort M, Vilella F, Moreno I, Simon C. Taxonomical and Functional Assessment of the Endometrial Microbiota in A Context of Recurrent Reproductive Failure: A Case Report. Pathogens. 2019 Oct 24; 8(4). PMID: 31653041; PMCID: PMC6963572.
    Citations: 15     
  26. Niederberger C, Pellicer A, Simon C, Kathrins M, Goldstein M, Sigman M, Schlegel PN, Munné S, Gardner DK, Cobo A, Coutifaris C, Donnez J, Taylor HS, Giudice LC, Fauser BCJM, Lindheim SR, Rosenwaks Z, Casper RF, de Ziegler D, Gibbons WE, Paulson RJ, Laufer N, Klock SC, Mendola P, Sauer MV. 25 historic papers: an ASRM 75th birthday gift from Fertility and Sterility. Fertil Steril. 2019 10; 112(4 Suppl1):e2-e27. PMID: 31623734.
    Citations:    Fields:    Translation:Humans
  27. Simon C. Introduction: Preconceptional care: do we have to care? Fertil Steril. 2019 10; 112(4):611-612. PMID: 31561862.
    Citations: 1     Fields:    Translation:Humans
  28. Niederberger C, Pellicer A, Simon C. Happy Birthday to ASRM from Fertility and Sterility. Fertil Steril. 2019 10; 112(4 Suppl1):e1. PMID: 31623722.
    Citations:    Fields:    Translation:Humans
  29. Carrasquillo RJ, Kohn TP, Cinnioglu C, Rubio C, Simon C, Ramasamy R, Al-Asmar N. Advanced paternal age does not affect embryo aneuploidy following blastocyst biopsy in egg donor cycles. J Assist Reprod Genet. 2019 Oct; 36(10):2039-2045. PMID: 31385121.
    Citations: 6     Fields:    Translation:Humans
  30. Bulletti C, Simon C. Bioengineered uterus: a path toward ectogenesis. Fertil Steril. 2019 09; 112(3):446-447. PMID: 31371052.
    Citations: 1     Fields:    Translation:Humans
  31. Simon C, Romero R. Preconceptional care, where reproductive medicine meets obstetrics: the origins of lifetime health. Fertil Steril. 2019 04; 111(4):657-658. PMID: 30929724.
    Citations:    Fields:    Translation:Humans
  32. Moreno I, Simon C. An endometrial pathology in the inflammation cloud that can be accessed with a microbial app. Fertil Steril. 2019 04; 111(4):679-680. PMID: 30871763.
    Citations: 1     Fields:    Translation:Humans
  33. Santamaria X, Mas A, Cervelló I, Taylor HS, Simon C. Reply: Bone marrow-derived endometrial cells: what you see is what you get. Hum Reprod Update. 2019 03 01; 25(2):274-275. PMID: 30601981.
    Citations: 2     Fields:    Translation:HumansCells
  34. Simon C. To what extent is the testing of the reproductive risk of a couple aiming to conceive meaningful in the contemporary clinical context? Fertil Steril. 2019 02; 111(2):227-228. PMID: 30642572.
    Citations:    Fields:    Translation:Humans
  35. Capalbo A, Chokoshvili D, Dugoff L, Franasiak J, Gleicher N, Pennings G, Simon C. Should the reproductive risk of a couple aiming to conceive be tested in the contemporary clinical context? Fertil Steril. 2019 02; 111(2):229-238. PMID: 30642571.
    Citations:    Fields:    Translation:Humans
  36. Santamaria X, Mas A, Cervelló I, Taylor H, Simon C. Uterine stem cells: from basic research to advanced cell therapies. Hum Reprod Update. 2018 11 01; 24(6):673-693. PMID: 30239705.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  37. Moreno I, Simon C. Deciphering the effect of reproductive tract microbiota on human reproduction. Reprod Med Biol. 2019 Jan; 18(1):40-50. PMID: 30655720; PMCID: PMC6332752.
    Citations: 18     
  38. Moreno I, Simon C. Relevance of assessing the uterine microbiota in infertility. Fertil Steril. 2018 08; 110(3):337-343. PMID: 30098680.
    Citations: 35     Fields:    Translation:HumansCells
  39. Simon C. Introduction: Do microbes in the female reproductive function matter? Fertil Steril. 2018 08; 110(3):325-326. PMID: 30037698.
    Citations: 8     Fields:    Translation:Humans
  40. Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, Paulson RJ, Goldfarb JM, Brännström M, Donnez J, Silber S, Dolmans MM, Simpson JL, Handyside AH, Munné S, Eguizabal C, Montserrat N, Izpisua Belmonte JC, Trounson A, Simon C, Tulandi T, Giudice LC, Norman RJ, Hsueh AJ, Sun Y, Laufer N, Kochman R, Eldar-Geva T, Lunenfeld B, Ezcurra D, D'Hooghe T, Fauser BCJM, Tarlatzis BC, Meldrum DR, Casper RF, Fatemi HM, Devroey P, Galliano D, Wikland M, Sigman M, Schoor RA, Goldstein M, Lipshultz LI, Schlegel PN, Hussein A, Oates RD, Brannigan RE, Ross HE, Pennings G, Klock SC, Brown S, Van Steirteghem A, Rebar RW, LaBarbera AR. Forty years of IVF. Fertil Steril. 2018 07 15; 110(2):185-324.e5. PMID: 30053940.
    Citations: 47     Fields:    Translation:Humans
  41. Simon C, Greening DW, Bolumar D, Balaguer N, Salamonsen LA, Vilella F. Extracellular Vesicles in Human Reproduction in Health and Disease. Endocr Rev. 2018 06 01; 39(3):292-332. PMID: 29390102.
    Citations: 48     Fields:    Translation:HumansCells
  42. Milan M, Mateu E, Blesa D, Clemente-Ciscar M, Simon C. Fetal sex determination in twin pregnancies using cell free fetal DNA analysis. Prenat Diagn. 2018 Apr 23. PMID: 29683524.
    Citations: 6     Fields:    
  43. Moreno I, Cicinelli E, Garcia-Grau I, Gonzalez-Monfort M, Bau D, Vilella F, De Ziegler D, Resta L, Valbuena D, Simon C. The diagnosis of chronic endometritis in infertile asymptomatic women: a comparative study of histology, microbial cultures, hysteroscopy, and molecular microbiology. Am J Obstet Gynecol. 2018 06; 218(6):602.e1-602.e16. PMID: 29477653.
    Citations: 30     Fields:    Translation:HumansCells
  44. Valdes CT, Schutt A, Simon C. Implantation failure of endometrial origin: it is not pathology, but our failure to synchronize the developing embryo with a receptive endometrium. Fertil Steril. 2017 07; 108(1):15-18. PMID: 28668151.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  45. Valbuena D, Valdes CT, Simon C. Introduction: Endometrial function: facts, urban legends, and an eye to the future. Fertil Steril. 2017 07; 108(1):4-8. PMID: 28601409.
    Citations: 4     Fields:    Translation:HumansAnimals
  46. Simon C. Introduction: To transfer or not transfer…a mosaic embryo, that is the question. Fertil Steril. 2017 05; 107(5):1083-1084. PMID: 28433365.
    Citations: 2     Fields:    Translation:Humans
  47. Simon C. Why should patients experience infertility or poor outcomes before using assisted reproductive technologies? Fertil Steril. 2017 04; 107(4):878-879. PMID: 28366414.
    Citations:    Fields:    Translation:Humans
  48. Comstock IA, Diaz-Gimeno P, Cabanillas S, Bellver J, Sebastian-Leon P, Shah M, Schutt A, Valdes CT, Ruiz-Alonso M, Valbuena D, Simon C, Lathi RB. Does an increased body mass index affect endometrial gene expression patterns in infertile patients? A functional genomics analysis. Fertil Steril. 2017 Mar; 107(3):740-748.e2. PMID: 27919438.
    Citations: 10     Fields:    Translation:HumansCells
  49. Moreno I, Codoñer FM, Vilella F, Valbuena D, Martinez-Blanch JF, Jimenez-Almazán J, Alonso R, Alamá P, Remohí J, Pellicer A, Ramon D, Simon C. Evidence that the endometrial microbiota has an effect on implantation success or failure. Am J Obstet Gynecol. 2016 Dec; 215(6):684-703. PMID: 27717732.
    Citations: 149     Fields:    Translation:HumansCells
  50. Medrano JV, Rombaut C, Simon C, Pellicer A, Goossens E. Human spermatogonial stem cells display limited proliferation in vitro under mouse spermatogonial stem cell culture conditions. Fertil Steril. 2016 Nov; 106(6):1539-1549.e8. PMID: 27490045.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  51. Sermon K, Capalbo A, Cohen J, Coonen E, De Rycke M, De Vos A, Delhanty J, Fiorentino F, Gleicher N, Griesinger G, Grifo J, Handyside A, Harper J, Kokkali G, Mastenbroek S, Meldrum D, Meseguer M, Montag M, Munné S, Rienzi L, Rubio C, Scott K, Scott R, Simon C, Swain J, Treff N, Ubaldi F, Vassena R, Vermeesch JR, Verpoest W, Wells D, Geraedts J. The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists. Mol Hum Reprod. 2016 08; 22(8):845-57. PMID: 27256483; PMCID: PMC4986417.
    Citations: 29     Fields:    Translation:Humans
  52. Meldrum DR, Casper RF, Diez-Juan A, Simon C, Domar AD, Frydman R. Aging and the environment affect gamete and embryo potential: can we intervene? Fertil Steril. 2016 Mar; 105(3):548-559. PMID: 26812244.
    Citations: 37     Fields:    Translation:AnimalsCells
  53. Simon C, Sakkas D, Gardner DK, Critchley HO. Biomarkers in reproductive medicine: the quest for new answers. Hum Reprod Update. 2015 Nov-Dec; 21(6):695-7. PMID: 26386470.
    Citations: 5     Fields:    
  54. Martin J, Yi Y, Alberola T, Rodríguez-Iglesias B, Jiménez-Almazán J, Li Q, Du H, Alama P, Ruiz A, Bosch E, Garrido N, Simon C. Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology. Fertil Steril. 2015 Nov; 104(5):1286-93. PMID: 26354092.
    Citations: 18     Fields:    Translation:Humans
  55. Vera-Rodriguez M, Chavez SL, Rubio C, Reijo Pera RA, Simon C. Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis. Nat Commun. 2015 Jul 07; 6:7601. PMID: 26151134.
    Citations: 37     Fields:    Translation:Humans
  56. Miravet-Valenciano JA, Rincon-Bertolin A, Vilella F, Simon C. Understanding and improving endometrial receptivity. Curr Opin Obstet Gynecol. 2015 Jun; 27(3):187-92. PMID: 25827647.
    Citations: 33     Fields:    Translation:Humans
  57. Aleixandre-Benavent R, Simon C, Fauser BC. Trends in clinical reproductive medicine research: 10 years of growth. Fertil Steril. 2015 Jul; 104(1):131-7.e5. PMID: 25936232.
    Citations: 7     Fields:    Translation:Humans
  58. Thouas GA, Dominguez F, Green MP, Vilella F, Simon C, Gardner DK. Soluble ligands and their receptors in human embryo development and implantation. Endocr Rev. 2015 Feb; 36(1):92-130. PMID: 25548832.
    Citations: 25     Fields:    Translation:Humans
  59. Medrano JV, Simon C, Pera RR. Human germ cell differentiation from pluripotent embryonic stem cells and induced pluripotent stem cells. Methods Mol Biol. 2014; 1154:563-78. PMID: 24782029.
    Citations: 1     Fields:    Translation:HumansCells
  60. Galan A, Diaz-Gimeno P, Poo ME, Valbuena D, Sanchez E, Ruiz V, Dopazo J, Montaner D, Conesa A, Simon C. Defining the genomic signature of totipotency and pluripotency during early human development. PLoS One. 2013; 8(4):e62135. PMID: 23614026.
    Citations: 12     Fields:    Translation:HumansCells
  61. Paule S, Aljofan M, Simon C, Rombauts LJ, Nie G. Cleavage of endometrial a-integrins into their functional forms is mediated by proprotein convertase 5/6. Hum Reprod. 2012 Sep; 27(9):2766-74. PMID: 22740495.
    Citations: 9     Fields:    Translation:HumansCells
  62. Garrido-Gómez T, Dominguez F, Quiñonero A, Estella C, Vilella F, Pellicer A, Simon C. Annexin A2 is critical for embryo adhesiveness to the human endometrium by RhoA activation through F-actin regulation. FASEB J. 2012 Sep; 26(9):3715-27. PMID: 22645245.
    Citations: 21     Fields:    Translation:HumansCells
  63. Ensenat-Waser R, Pellicer A, Simon C. Reprogrammed induced pluripotent stem cells: how suitable could they be in reproductive medicine? Fertil Steril. 2009 Apr; 91(4):971-4. PMID: 19200985.
    Citations: 3     Fields:    Translation:HumansCells
  64. Busso CE, Melo MA, Fernandez M, Pellicer A, Simon C. Implantation in IVF. Int Surg. 2006 Sep-Oct; 91(5 Suppl):S63-76. PMID: 17436606.
    Citations: 2     Fields:    Translation:Humans
  65. Garrido N, Meseguer M, Simon C, Pellicer A, Remohi J. Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility. Asian J Androl. 2004 Mar; 6(1):59-65. PMID: 15064836.
    Citations: 27     Fields:    Translation:HumansCells
  66. Simon C, Domínguez F, Valbuena D, Pellicer A. The role of estrogen in uterine receptivity and blastocyst implantation. Trends Endocrinol Metab. 2003 Jul; 14(5):197-9. PMID: 12826321.
    Citations: 17     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.