Harvard Catalyst Profiles

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Carlos Simon, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Garrido-Gomez T, Castillo-Marco N, Clemente-Ciscar M, Cordero T, Muñoz-Blat I, Amadoz A, Jimenez-Almazan J, Monfort-Ortiz R, Climent R, Perales-Marin A, Simon C. Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia. Elife. 2021 10 28; 10. PMID: 34709177.
    Citations:    Fields:    
  2. Simon C. Consensus vision. Fertil Steril. 2021 07; 116(1):13-14. PMID: 34148581.
    Citations:    Fields:    Translation:Humans
  3. Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L, Simon C. In vitro fertilization and andrology laboratory in 2030: expert visions. Fertil Steril. 2021 07; 116(1):4-12. PMID: 34148588.
    Citations:    Fields:    Translation:Humans
  4. Simon C, Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L. In vitro fertilization and andrology laboratories in 2030. Fertil Steril. 2021 07; 116(1):2-3. PMID: 34148585.
    Citations:    Fields:    Translation:Humans
  5. Vilella F, Wang W, Moreno I, Quake SR, Simon C. Understanding the human endometrium in the 21st century. Am J Obstet Gynecol. 2021 07; 225(1):1-2. PMID: 34023092.
    Citations:    Fields:    Translation:Humans
  6. Ruiz-Alonso M, Valbuena D, Gomez C, Cuzzi J, Simon C. Endometrial Receptivity Analysis (ERA): data versus opinions. Hum Reprod Open. 2021; 2021(2):hoab011. PMID: 33880420.
    Citations: 1     
  7. Rubio C, Racowsky C, Barad DH, Scott RT, Simon C. Noninvasive preimplantation genetic testing for aneuploidy in spent culture medium as a substitute for trophectoderm biopsy. Fertil Steril. 2021 04; 115(4):841-849. PMID: 33741125.
    Citations: 1     Fields:    Translation:Humans
  8. Simon C. Noninvasive preimplantation genetic testing for aneuploidy in spent blastocyst media will substitute for trophectoderm biopsy. Fertil Steril. 2021 04; 115(4):840. PMID: 33726897.
    Citations:    Fields:    Translation:Humans
  9. Foulk R, Sakkas D, Kayali R, Valbuena D, Simon C, Cuzzi J. Severe acute respiratory syndrome coronavirus 2 immunity: infective and naive incidence in fertility clinics after lockdown. Am J Obstet Gynecol. 2021 07; 225(1):103-105. PMID: 33716073.
    Citations:    Fields:    Translation:HumansPHPublic Health
  10. O'Brien JE, Adashi EY, Simon C. Darwin meets Mendel in the reproductive medicine field: Homo sapiens 2.0 is inevitable. Fertil Steril. 2021 04; 115(4):850-851. PMID: 33642062.
    Citations:    Fields:    Translation:Humans
  11. Vilella F, Simon C. Reproductive medicine, as seen through single-cell glasses. Fertil Steril. 2021 02; 115(2):296-297. PMID: 33386110.
    Citations:    Fields:    Translation:Humans
  12. Capalbo A, Rubio C, Simon C. Testing the mathematical model for PGT-A inefficiency with scientific sources demonstrates the efficacy of PGT-A. Hum Reprod. 2020 09 01; 35(9):2163-2165. PMID: 32766771.
    Citations: 1     Fields:    Translation:Humans
  13. Simon C. Introduction: How evident is the evidence? Fertil Steril. 2020 Jul 02. PMID: 32624212.
    Citations:    Fields:    
  14. Simon C. Introduction: How evident is the evidence? Fertil Steril. 2020 06; 113(6):1091-1092. PMID: 32482243.
    Citations: 1     Fields:    Translation:Humans
  15. Girardi L, Serdarogullari M, Patassini C, Poli M, Fabiani M, Caroselli S, Coban O, Findikli N, Boynukalin FK, Bahceci M, Chopra R, Canipari R, Cimadomo D, Rienzi L, Ubaldi F, Hoffmann E, Rubio C, Simon C, Capalbo A. Incidence, Origin, and Predictive Model for the Detection and Clinical Management of Segmental Aneuploidies in Human Embryos. Am J Hum Genet. 2020 04 02; 106(4):525-534. PMID: 32220293.
    Citations: 10     Fields:    Translation:HumansCells
  16. Roque M, Simon C. Time to pregnancy: as important for patients as underestimated by doctors. Fertil Steril. 2020 03; 113(3):522-523. PMID: 32111473.
    Citations:    Fields:    Translation:Humans
  17. Simon C. Operative hysteroscopy should be repeated as many times as necessary for the treatment of refractory Asherman syndrome versus is there any alternative therapy worth considering? Fertil Steril. 2020 03; 113(3):510. PMID: 32089254.
    Citations:    Fields:    Translation:Humans
  18. Simon C, Sakkas D, Gardner D, Critchley H. Precision medicine in human reproduction. Special Issue. Biol Reprod. 2019 12 24; 101(6):1075. PMID: 31616936.
    Citations: 2     Fields:    Translation:Humans
  19. Garcia-Grau I, Simon C, Moreno I. Uterine microbiome-low biomass and high expectations†. Biol Reprod. 2019 12 24; 101(6):1102-1114. PMID: 30544156.
    Citations: 6     Fields:    Translation:Humans
  20. Garrido-Gomez T, Quiñonero A, Dominguez F, Rubert L, Perales A, Hajjar KA, Simon C. Preeclampsia: a defect in decidualization is associated with deficiency of Annexin A2. Am J Obstet Gynecol. 2020 04; 222(4):376.e1-376.e17. PMID: 31738896.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  21. Garcia-Grau I, Perez-Villaroya D, Bau D, Gonzalez-Monfort M, Vilella F, Moreno I, Simon C. Taxonomical and Functional Assessment of the Endometrial Microbiota in A Context of Recurrent Reproductive Failure: A Case Report. Pathogens. 2019 Oct 24; 8(4). PMID: 31653041.
    Citations: 7     
  22. Niederberger C, Pellicer A, Simon C. Happy Birthday to ASRM from Fertility and Sterility. Fertil Steril. 2019 10; 112(4 Suppl1):e1. PMID: 31623722.
    Citations:    Fields:    Translation:Humans
  23. Simon C. Introduction: Preconceptional care: do we have to care? Fertil Steril. 2019 10; 112(4):611-612. PMID: 31561862.
    Citations: 1     Fields:    Translation:Humans
  24. Niederberger C, Pellicer A, Simon C, Kathrins M, Goldstein M, Sigman M, Schlegel PN, Munné S, Gardner DK, Cobo A, Coutifaris C, Donnez J, Taylor HS, Giudice LC, Fauser BCJM, Lindheim SR, Rosenwaks Z, Casper RF, de Ziegler D, Gibbons WE, Paulson RJ, Laufer N, Klock SC, Mendola P, Sauer MV. 25 historic papers: an ASRM 75th birthday gift from Fertility and Sterility. Fertil Steril. 2019 10; 112(4 Suppl1):e2-e27. PMID: 31623734.
    Citations:    Fields:    Translation:Humans
  25. Carrasquillo RJ, Kohn TP, Cinnioglu C, Rubio C, Simon C, Ramasamy R, Al-Asmar N. Advanced paternal age does not affect embryo aneuploidy following blastocyst biopsy in egg donor cycles. J Assist Reprod Genet. 2019 Oct; 36(10):2039-2045. PMID: 31385121.
    Citations: 2     Fields:    Translation:Humans
  26. Bulletti C, Simon C. Bioengineered uterus: a path toward ectogenesis. Fertil Steril. 2019 09; 112(3):446-447. PMID: 31371052.
    Citations: 1     Fields:    Translation:Humans
  27. Simon C, Romero R. Preconceptional care, where reproductive medicine meets obstetrics: the origins of lifetime health. Fertil Steril. 2019 04; 111(4):657-658. PMID: 30929724.
    Citations:    Fields:    Translation:Humans
  28. Moreno I, Simon C. An endometrial pathology in the inflammation cloud that can be accessed with a microbial app. Fertil Steril. 2019 04; 111(4):679-680. PMID: 30871763.
    Citations:    Fields:    Translation:Humans
  29. Santamaria X, Mas A, Cervelló I, Taylor HS, Simon C. Reply: Bone marrow-derived endometrial cells: what you see is what you get. Hum Reprod Update. 2019 03 01; 25(2):274-275. PMID: 30601981.
    Citations: 1     Fields:    Translation:HumansCells
  30. Simon C. To what extent is the testing of the reproductive risk of a couple aiming to conceive meaningful in the contemporary clinical context? Fertil Steril. 2019 02; 111(2):227-228. PMID: 30642572.
    Citations:    Fields:    Translation:Humans
  31. Capalbo A, Chokoshvili D, Dugoff L, Franasiak J, Gleicher N, Pennings G, Simon C. Should the reproductive risk of a couple aiming to conceive be tested in the contemporary clinical context? Fertil Steril. 2019 02; 111(2):229-238. PMID: 30642571.
    Citations:    Fields:    Translation:Humans
  32. Moreno I, Simon C. Deciphering the effect of reproductive tract microbiota on human reproduction. Reprod Med Biol. 2019 Jan; 18(1):40-50. PMID: 30655720.
    Citations: 14     
  33. Santamaria X, Mas A, Cervelló I, Taylor H, Simon C. Uterine stem cells: from basic research to advanced cell therapies. Hum Reprod Update. 2018 11 01; 24(6):673-693. PMID: 30239705.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  34. Moreno I, Simon C. Relevance of assessing the uterine microbiota in infertility. Fertil Steril. 2018 08; 110(3):337-343. PMID: 30098680.
    Citations: 23     Fields:    Translation:HumansCells
  35. Simon C. Introduction: Do microbes in the female reproductive function matter? Fertil Steril. 2018 08; 110(3):325-326. PMID: 30037698.
    Citations: 7     Fields:    Translation:Humans
  36. Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, Paulson RJ, Goldfarb JM, Brännström M, Donnez J, Silber S, Dolmans MM, Simpson JL, Handyside AH, Munné S, Eguizabal C, Montserrat N, Izpisua Belmonte JC, Trounson A, Simon C, Tulandi T, Giudice LC, Norman RJ, Hsueh AJ, Sun Y, Laufer N, Kochman R, Eldar-Geva T, Lunenfeld B, Ezcurra D, D'Hooghe T, Fauser BCJM, Tarlatzis BC, Meldrum DR, Casper RF, Fatemi HM, Devroey P, Galliano D, Wikland M, Sigman M, Schoor RA, Goldstein M, Lipshultz LI, Schlegel PN, Hussein A, Oates RD, Brannigan RE, Ross HE, Pennings G, Klock SC, Brown S, Van Steirteghem A, Rebar RW, LaBarbera AR. Forty years of IVF. Fertil Steril. 2018 07 15; 110(2):185-324.e5. PMID: 30053940.
    Citations: 32     Fields:    Translation:Humans
  37. Simon C, Greening DW, Bolumar D, Balaguer N, Salamonsen LA, Vilella F. Extracellular Vesicles in Human Reproduction in Health and Disease. Endocr Rev. 2018 06 01; 39(3):292-332. PMID: 29390102.
    Citations: 35     Fields:    Translation:HumansCells
  38. Milan M, Mateu E, Blesa D, Clemente-Ciscar M, Simon C. Fetal sex determination in twin pregnancies using cell free fetal DNA analysis. Prenat Diagn. 2018 Apr 23. PMID: 29683524.
    Citations: 6     Fields:    
  39. Moreno I, Cicinelli E, Garcia-Grau I, Gonzalez-Monfort M, Bau D, Vilella F, De Ziegler D, Resta L, Valbuena D, Simon C. The diagnosis of chronic endometritis in infertile asymptomatic women: a comparative study of histology, microbial cultures, hysteroscopy, and molecular microbiology. Am J Obstet Gynecol. 2018 06; 218(6):602.e1-602.e16. PMID: 29477653.
    Citations: 15     Fields:    Translation:HumansCells
  40. Valdes CT, Schutt A, Simon C. Implantation failure of endometrial origin: it is not pathology, but our failure to synchronize the developing embryo with a receptive endometrium. Fertil Steril. 2017 07; 108(1):15-18. PMID: 28668151.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  41. Valbuena D, Valdes CT, Simon C. Introduction: Endometrial function: facts, urban legends, and an eye to the future. Fertil Steril. 2017 07; 108(1):4-8. PMID: 28601409.
    Citations: 4     Fields:    Translation:HumansAnimals
  42. Simon C. Introduction: To transfer or not transfer…a mosaic embryo, that is the question. Fertil Steril. 2017 05; 107(5):1083-1084. PMID: 28433365.
    Citations: 1     Fields:    Translation:Humans
  43. Simon C. Why should patients experience infertility or poor outcomes before using assisted reproductive technologies? Fertil Steril. 2017 04; 107(4):878-879. PMID: 28366414.
    Citations:    Fields:    Translation:Humans
  44. Comstock IA, Diaz-Gimeno P, Cabanillas S, Bellver J, Sebastian-Leon P, Shah M, Schutt A, Valdes CT, Ruiz-Alonso M, Valbuena D, Simon C, Lathi RB. Does an increased body mass index affect endometrial gene expression patterns in infertile patients? A functional genomics analysis. Fertil Steril. 2017 Mar; 107(3):740-748.e2. PMID: 27919438.
    Citations: 6     Fields:    Translation:HumansCells
  45. Moreno I, Codoñer FM, Vilella F, Valbuena D, Martinez-Blanch JF, Jimenez-Almazán J, Alonso R, Alamá P, Remohí J, Pellicer A, Ramon D, Simon C. Evidence that the endometrial microbiota has an effect on implantation success or failure. Am J Obstet Gynecol. 2016 Dec; 215(6):684-703. PMID: 27717732.
    Citations: 108     Fields:    Translation:HumansCells
  46. Medrano JV, Rombaut C, Simon C, Pellicer A, Goossens E. Human spermatogonial stem cells display limited proliferation in vitro under mouse spermatogonial stem cell culture conditions. Fertil Steril. 2016 Nov; 106(6):1539-1549.e8. PMID: 27490045.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  47. Sermon K, Capalbo A, Cohen J, Coonen E, De Rycke M, De Vos A, Delhanty J, Fiorentino F, Gleicher N, Griesinger G, Grifo J, Handyside A, Harper J, Kokkali G, Mastenbroek S, Meldrum D, Meseguer M, Montag M, Munné S, Rienzi L, Rubio C, Scott K, Scott R, Simon C, Swain J, Treff N, Ubaldi F, Vassena R, Vermeesch JR, Verpoest W, Wells D, Geraedts J. The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists. Mol Hum Reprod. 2016 08; 22(8):845-57. PMID: 27256483.
    Citations: 23     Fields:    Translation:Humans
  48. Meldrum DR, Casper RF, Diez-Juan A, Simon C, Domar AD, Frydman R. Aging and the environment affect gamete and embryo potential: can we intervene? Fertil Steril. 2016 Mar; 105(3):548-559. PMID: 26812244.
    Citations: 27     Fields:    Translation:AnimalsCells
  49. Simon C, Sakkas D, Gardner DK, Critchley HO. Biomarkers in reproductive medicine: the quest for new answers. Hum Reprod Update. 2015 Nov-Dec; 21(6):695-7. PMID: 26386470.
    Citations: 5     Fields:    
  50. Martin J, Yi Y, Alberola T, Rodríguez-Iglesias B, Jiménez-Almazán J, Li Q, Du H, Alama P, Ruiz A, Bosch E, Garrido N, Simon C. Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology. Fertil Steril. 2015 Nov; 104(5):1286-93. PMID: 26354092.
    Citations: 15     Fields:    Translation:Humans
  51. Vera-Rodriguez M, Chavez SL, Rubio C, Reijo Pera RA, Simon C. Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis. Nat Commun. 2015 Jul 07; 6:7601. PMID: 26151134.
    Citations: 27     Fields:    Translation:Humans
  52. Miravet-Valenciano JA, Rincon-Bertolin A, Vilella F, Simon C. Understanding and improving endometrial receptivity. Curr Opin Obstet Gynecol. 2015 Jun; 27(3):187-92. PMID: 25827647.
    Citations: 27     Fields:    Translation:Humans
  53. Aleixandre-Benavent R, Simon C, Fauser BC. Trends in clinical reproductive medicine research: 10 years of growth. Fertil Steril. 2015 Jul; 104(1):131-7.e5. PMID: 25936232.
    Citations: 5     Fields:    Translation:Humans
  54. Thouas GA, Dominguez F, Green MP, Vilella F, Simon C, Gardner DK. Soluble ligands and their receptors in human embryo development and implantation. Endocr Rev. 2015 Feb; 36(1):92-130. PMID: 25548832.
    Citations: 22     Fields:    Translation:Humans
  55. Medrano JV, Simon C, Pera RR. Human germ cell differentiation from pluripotent embryonic stem cells and induced pluripotent stem cells. Methods Mol Biol. 2014; 1154:563-78. PMID: 24782029.
    Citations:    Fields:    Translation:HumansCells
  56. Galan A, Diaz-Gimeno P, Poo ME, Valbuena D, Sanchez E, Ruiz V, Dopazo J, Montaner D, Conesa A, Simon C. Defining the genomic signature of totipotency and pluripotency during early human development. PLoS One. 2013; 8(4):e62135. PMID: 23614026.
    Citations: 11     Fields:    Translation:HumansCells
  57. Paule S, Aljofan M, Simon C, Rombauts LJ, Nie G. Cleavage of endometrial a-integrins into their functional forms is mediated by proprotein convertase 5/6. Hum Reprod. 2012 Sep; 27(9):2766-74. PMID: 22740495.
    Citations: 8     Fields:    Translation:HumansCells
  58. Garrido-Gómez T, Dominguez F, Quiñonero A, Estella C, Vilella F, Pellicer A, Simon C. Annexin A2 is critical for embryo adhesiveness to the human endometrium by RhoA activation through F-actin regulation. FASEB J. 2012 Sep; 26(9):3715-27. PMID: 22645245.
    Citations: 18     Fields:    Translation:HumansCells
  59. Ensenat-Waser R, Pellicer A, Simon C. Reprogrammed induced pluripotent stem cells: how suitable could they be in reproductive medicine? Fertil Steril. 2009 Apr; 91(4):971-4. PMID: 19200985.
    Citations: 3     Fields:    Translation:HumansCells
  60. Busso CE, Melo MA, Fernandez M, Pellicer A, Simon C. Implantation in IVF. Int Surg. 2006 Sep-Oct; 91(5 Suppl):S63-76. PMID: 17436606.
    Citations: 2     Fields:    Translation:Humans
  61. Garrido N, Meseguer M, Simon C, Pellicer A, Remohi J. Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility. Asian J Androl. 2004 Mar; 6(1):59-65. PMID: 15064836.
    Citations: 25     Fields:    Translation:HumansCells
  62. Simon C, Domínguez F, Valbuena D, Pellicer A. The role of estrogen in uterine receptivity and blastocyst implantation. Trends Endocrinol Metab. 2003 Jul; 14(5):197-9. PMID: 12826321.
    Citations: 13     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.