Harvard Catalyst Profiles

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Joshua Samuel Waitzman, M.D., Ph.D.


Brown University, Providence, RISc.B.06/2007Biophysics
Northwestern University, Evanston, ILPh.D.09/2013Life Sciences
Feinberg School of Medicine, Northwestern University, Chicago, ILM.D.05/2015
McGaw Medical Center, Northwestern University, Chicago, IL06/2017Resident, Internal Medicine
McGaw Medical Center, Northwestern University, Chicago, IL06/2019Fellow, Nephrology
Beth Israel Deaconess Medical Center, Boston, MA06/2021Research Fellow, Nephrology
Phi Beta Kappa
Morris Povar Prize in Biotechnology and Physiology
2010 - 2013
Fannie and John Hertz Foundation Fellowship
Alpha Omega Alpha
Excellence in Teaching Award

I am a Nephrologist at Beth Israel Deaconess Medical Center. I see patients at Beth Israel Deaconess-Lexington and study the molecular mechanisms that cause focal segmental glomerulosclerosis.

I completed my MD/PhD training in biochemistry and biophysics at Northwestern. During my graduate work in the laboratory of Dr. Sarah Rice, I determined the mechanism of a kinesin motor involved in mitosis and identified a novel phosphoregulatory mechanism that governs its activity.

I completed my residency in Internal Medicine at Northwestern Memorial Hosptial in 2017. I completed two years of clinical Nephrology training at Northwestern, and then continued my research training at BIDMC.

My research focuses on the biochemistry and biophysics of proteins that cause kidney disease, particularly ApoL1 and INF2.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ko BS, Pivert KA, Rope R, Burgner AM, Waitzman JS, Halbach SM, Boyle SM, Chan L, Sozio SM. Nephrology Trainee Education Needs Assessment: Five Years and a Pandemic Later. Kidney Med. 2022 Nov; 4(11):100548. PMID: 36275043; PMCID: PMC9575331.
  2. Waitzman J, Canney M, Hiremath S. Finerenone: Fiddling With Hyperkalemia? Am J Kidney Dis. 2021 11; 78(5):760. PMID: 34400243.
    Citations:    Fields:    Translation:Humans
  3. Pivert KA, Boyle SM, Halbach SM, Chan L, Shah HH, Waitzman JS, Mehdi A, Norouzi S, Sozio SM. Impact of the COVID-19 Pandemic on Nephrology Fellow Training and Well-Being in the United States: A National Survey. J Am Soc Nephrol. 2021 05 03; 32(5):1236-1248. PMID: 33658283; PMCID: PMC8259681.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  4. Waitzman JS, Lin J. Ten years in: APOL1 reaches beyond the kidney. Curr Opin Nephrol Hypertens. 2019 07; 28(4):375-382. PMID: 31082862; PMCID: PMC7340511.
    Citations: 1     Fields:    Translation:Humans
  5. Chae YK, Chiec L, Adney SK, Waitzman J, Costa R, Carneiro B, Matsangou M, Agulnik M, Kopp P, Giles F. Posterior reversible encephalopathy syndrome and takotsubo cardiomyopathy associated with lenvatinib therapy for thyroid cancer: a case report and review. Oncotarget. 2018 Jun 15; 9(46):28281-28289. PMID: 29963277.
    Citations: 5     Fields:    
  6. Waitzman JS, Wilkins JT, Lin J. APOL1 Sends Its REGARDS to Cardiovascular Disease. Circ Genom Precis Med. 2018 06; 11(6):e002212. PMID: 29899046; PMCID: PMC6003424.
    Citations:    Fields:    Translation:Humans
  7. Bickel KG, Mann BJ, Waitzman JS, Poor TA, Rice SE, Wadsworth P. Src family kinase phosphorylation of the motor domain of the human kinesin-5, Eg5. Cytoskeleton (Hoboken). 2017 Sep; 74(9):317-330. PMID: 28646493; PMCID: PMC5735839.
    Citations: 8     Fields:    Translation:HumansCells
  8. Smith KP, Gifford KM, Waitzman JS, Rice SE. Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects. Proteins. 2015 Jan; 83(1):25-36. PMID: 24833420.
    Citations: 8     Fields:    Translation:HumansCells
  9. Waitzman JS, Rice SE. Mechanism and regulation of kinesin-5, an essential motor for the mitotic spindle. Biol Cell. 2014 Jan; 106(1):1-12. PMID: 24125467; PMCID: PMC4034379.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  10. Vinogradova MV, Malanina GG, Waitzman JS, Rice SE, Fletterick RJ. Plant Kinesin-Like Calmodulin Binding Protein Employs Its Regulatory Domain for Dimerization. PLoS One. 2013; 8(6):e66669. PMID: 23805258; PMCID: PMC3689661.
    Citations: 3     Fields:    Translation:AnimalsCells
  11. Waitzman JS, Larson AG, Cochran JC, Naber N, Cooke R, Jon Kull F, Pate E, Rice SE. The loop 5 element structurally and kinetically coordinates dimers of the human kinesin-5, Eg5. Biophys J. 2011 Dec 07; 101(11):2760-9. PMID: 22261065; PMCID: PMC3297777.
    Citations: 18     Fields:    Translation:HumansCells
  12. Duch J, Waitzman JS, Amaral LA. Quantifying the performance of individual players in a team activity. PLoS One. 2010 Jun 16; 5(6):e10937. PMID: 20585387.
    Citations: 46     Fields:    Translation:Humans
  13. Bauer JH, Chang C, Morris SN, Hozier S, Andersen S, Waitzman JS, Helfand SL. Expression of dominant-negative Dmp53 in the adult fly brain inhibits insulin signaling. Proc Natl Acad Sci U S A. 2007 Aug 14; 104(33):13355-60. PMID: 17686972; PMCID: PMC1948898.
    Citations: 41     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.