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Thomas Edouard W. Vanhove, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Pieters TT, Falke LL, Nguyen TQ, Verhaar MC, Florquin S, Bemelman FJ, Kers J, Vanhove T, Kuypers D, Goldschmeding R, Rookmaaker MB. Histological characteristics of Acute Tubular Injury during Delayed Graft Function predict renal function after renal transplantation. Physiol Rep. 2019 03; 7(5):e14000. PMID: 30821122.
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  2. Vanhove T, de Jonge H, de Loor H, Oorts M, de Hoon J, Pohanka A, Annaert P, Kuypers DRJ. Relationship between In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Systemic Tacrolimus Metabolite/Parent Drug Ratio in Renal Transplant Recipients and Healthy Volunteers. Drug Metab Dispos. 2018 11; 46(11):1507-1513. PMID: 30166405.
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  3. Vanhove T, Annaert P, Knops N, de Loor H, de Hoon J, Kuypers DRJ. In vivo CYP3A4 activity does not predict the magnitude of interaction between itraconazole and tacrolimus from an extended release formulation. Basic Clin Pharmacol Toxicol. 2019 Jan; 124(1):50-55. PMID: 29989304.
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  4. Kuypers DRJ, Vanhove T. Kuypers and Vanhove reply to 'Was 4ß-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker. Br J Clin Pharmacol. 2018 07; 84(7):1622-1623. PMID: 29691891.
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  5. Bellon H, Vandermeulen E, Verleden SE, Heigl T, Vriens H, Lammertyn E, Verlinden L, Vanhove T, Verstuyf M, Hoet P, Vos R, Verleden GM, Vanaudenaerde BM. The Effect of Immunosuppression on Airway Integrity. Transplantation. 2017 12; 101(12):2855-2861. PMID: 28471870.
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  6. Vanhove T, Hasan M, Annaert P, Oswald S, Kuypers DRJ. Pretransplant 4ß-hydroxycholesterol does not predict tacrolimus exposure or dose requirements during the first days after kidney transplantation. Br J Clin Pharmacol. 2017 Nov; 83(11):2406-2415. PMID: 28603840.
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  7. Vanhove T, Bouillon T, de Loor H, Annaert P, Kuypers D. Fexofenadine, a Putative In Vivo P-glycoprotein Probe, Fails to Predict Clearance of the Substrate Tacrolimus in Renal Recipients. Clin Pharmacol Ther. 2017 Dec; 102(6):989-996. PMID: 28437851.
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  8. Vanhove T, Kinashi H, Nguyen TQ, Metalidis C, Poesen K, Naesens M, Lerut E, Goldschmeding R, Kuypers DRJ. Tubulointerstitial expression and urinary excretion of connective tissue growth factor 3 months after renal transplantation predict interstitial fibrosis and tubular atrophy at 5 years in a retrospective cohort analysis. Transpl Int. 2017 Jul; 30(7):695-705. PMID: 28390067.
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  9. Vanhove T, Bouwsma H, Hilbrands L, Swen JJ, Spriet I, Annaert P, Vanaudenaerde B, Verleden G, Vos R, Kuypers DRJ. Determinants of the Magnitude of Interaction Between Tacrolimus and Voriconazole/Posaconazole in Solid Organ Recipients. Am J Transplant. 2017 Sep; 17(9):2372-2380. PMID: 28224698.
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  10. Meijers B, Metalidis C, Vanhove T, Poesen R, Kuypers D, Evenepoel P. A noninferiority trial comparing a heparin-grafted membrane plus citrate-containing dialysate versus regional citrate anticoagulation: results of the CiTED study. Nephrol Dial Transplant. 2017 04 01; 32(4):707-714. PMID: 28407129.
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  11. Vanhove T, Goldschmeding R, Kuypers D. Kidney Fibrosis: Origins and Interventions. Transplantation. 2017 Apr; 101(4):713-726. PMID: 27941433.
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  12. Vanhove T, Annaert P, Kuypers DRJ. Response to: 'Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'. Br J Clin Pharmacol. 2017 06; 83(6):1353-1356. PMID: 28168728.
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  13. Vanhove T, Spriet I, Annaert P, Maertens J, Van Cleemput J, Vos R, Kuypers D. Effect of the Direct Oral Anticoagulants Rivaroxaban and Apixaban on the Disposition of Calcineurin Inhibitors in Transplant Recipients. Ther Drug Monit. 2017 02; 39(1):77-82. PMID: 27861314.
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  14. Kuypers DR, Vanhove T. Predictive Modeling of Tacrolimus Dose Requirements: "All That Is Gold Does Not Glitter". Am J Transplant. 2017 04; 17(4):1144-1145. PMID: 27860253.
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  15. Vanhove T, de Jonge H, de Loor H, Annaert P, Diczfalusy U, Kuypers DR. Comparative performance of oral midazolam clearance and plasma 4ß-hydroxycholesterol to explain interindividual variability in tacrolimus clearance. Br J Clin Pharmacol. 2016 12; 82(6):1539-1549. PMID: 27501475.
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  16. Vanhove T, Remijsen Q, Kuypers D, Gillard P. Drug-drug interactions between immunosuppressants and antidiabetic drugs in the treatment of post-transplant diabetes mellitus. Transplant Rev (Orlando). 2017 04; 31(2):69-77. PMID: 27665059.
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  17. Vanhove T, Annaert P, Lambrechts D, Kuypers DRJ. Effect of ABCB1 diplotype on tacrolimus disposition in renal recipients depends on CYP3A5 and CYP3A4 genotype. Pharmacogenomics J. 2017 12; 17(6):556-562. PMID: 27378609.
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  18. Vanhove T, Vermeulen T, Annaert P, Lerut E, Kuypers DRJ. High Intrapatient Variability of Tacrolimus Concentrations Predicts Accelerated Progression of Chronic Histologic Lesions in Renal Recipients. Am J Transplant. 2016 10; 16(10):2954-2963. PMID: 27013142.
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  19. Vanhove T, Annaert P, Kuypers DR. Clinical determinants of calcineurin inhibitor disposition: a mechanistic review. Drug Metab Rev. 2016; 48(1):88-112. PMID: 26912097.
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  20. Ongenae F, Vanhove T, De Backere F, De Turck F. Intelligent task management platform for health care workers. Inform Health Soc Care. 2017 Mar; 42(2):122-134. PMID: 26890874.
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  21. Vanhove T, de Jonge H, de Loor H, Verbeke K, Kuypers DR. Response to 'Tacrolimus pharmacokinetics after kidney transplantation--Influence of changes in haematocrit and steroid dose'. Br J Clin Pharmacol. 2015 Dec; 80(6):1473-4. PMID: 26235051.
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  22. de Jonge H, Vanhove T, de Loor H, Verbeke K, Kuypers DR. Progressive decline in tacrolimus clearance after renal transplantation is partially explained by decreasing CYP3A4 activity and increasing haematocrit. Br J Clin Pharmacol. 2015 Sep; 80(3):548-59. PMID: 26114223.
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  23. De Backere F, Vanhove T, Dejonghe E, Feys M, Herinckx T, Vankelecom J, Decruyenaere J, De Turck F. Platform for efficient switching between multiple devices in the intensive care unit. Methods Inf Med. 2015; 54(1):5-15. PMID: 24903649.
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  24. Vanhove T, Kuypers D, Claes KJ, Evenepoel P, Meijers B, Naesens M, Vanrenterghem Y, Cornelis T, Bammens B. Reasons for dose reduction of mycophenolate mofetil during the first year after renal transplantation and its impact on graft outcome. Transpl Int. 2013 Aug; 26(8):813-21. PMID: 23746202.
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  25. Vandenput I, Vanhove T, Calster BV, Gorp TV, Moerman P, Verbist G, Vergote I, Amant F. The use of lymph vessel markers to predict endometrial cancer outcome. Int J Gynecol Cancer. 2010 Apr; 20(3):363-7. PMID: 20375798.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.