Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Abhishek Niroula, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Niroula A, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD, Barnes KC, Moscati A, Fornage M, Redline S, Psaty BM, Silverman EK, Weiss ST, Palmer ND, Vasan RS, Burchard EG, Kardia SLR, He J, Kaplan RC, Smith NL, Arnett DK, Schwartz DA, Correa A, de Andrade M, Guo X, Konkle BA, Custer B, Peralta JM, Gui H, Meyers DA, McGarvey ST, Chen IY, Shoemaker MB, Peyser PA, Broome JG, Gogarten SM, Wang FF, Wong Q, Montasser ME, Daya M, Kenny EE, North KE, Launer LJ, Cade BE, Bis JC, Cho MH, Lasky-Su J, Bowden DW, Cupples LA, Mak ACY, Becker LC, Smith JA, Kelly TN, Aslibekyan S, Heckbert SR, Tiwari HK, Yang IV, Heit JA, Lubitz SA, Johnsen JM, Curran JE, Wenzel SE, Weeks DE, Rao DC, Darbar D, Moon JY, Tracy RP, Buth EJ, Rafaels N, Loos RJF, Durda P, Liu Y, Hou L, Lee J, Kachroo P, Freedman BI, Levy D, Bielak LF, Hixson JE, Floyd JS, Whitsel EA, Ellinor PT, Irvin MR, Fingerlin TE, Raffield LM, Armasu SM, Wheeler MM, Sabino EC, Blangero J, Williams LK, Levy BD, Sheu WH, Roden DM, Boerwinkle E, Manson JE, Mathias RA, Desai P, Taylor KD, Johnson AD, Auer PL, Kooperberg C, Laurie CC, Blackwell TW, Smith AV, Zhao H, Lange E, Lange L, Rich SS, Rotter JI, Wilson JG, Scheet P, Kitzman JO, Lander ES, Engreitz JM, Ebert BL, Reiner AP, Jaiswal S, Abecasis G, Sankaran VG, Kathiresan S, Natarajan P. Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 2021 Mar; 591(7851):E27. PMID: 33707633.
    Citations:    Fields:    
  2. Mattsson J, Ekdahl L, Junghus F, Ajore R, Erlandsson E, Niroula A, Pertesi M, Frendéus B, Teige I, Nilsson B. Accelerating target deconvolution for therapeutic antibody candidates using highly parallelized genome editing. Nat Commun. 2021 02 24; 12(1):1277. PMID: 33627649.
    Citations:    Fields:    Translation:HumansCells
  3. Grahn THM, Niroula A, Végvári Á, Oburoglu L, Pertesi M, Warsi S, Safi F, Miharada N, Capellera-Garcia S, Siva K, Liu Y, Rörby E, Nilsson B, Zubarev RA, Karlsson S. Correction: S100A6 is a critical regulator of hematopoietic stem cells. Leukemia. 2020 Dec; 34(12):3439. PMID: 32665696.
    Citations:    Fields:    
  4. Honigberg MC, Zekavat SM, Niroula A, Griffin GK, Bick AG, Pirruccello JP, Nakao T, Whitsel EA, Farland LV, Laurie C, Kooperberg C, Manson JE, Gabriel S, Libby P, Reiner AP, Ebert BL, Natarajan P. Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women. Circulation. 2021 Feb 02; 143(5):410-423. PMID: 33161765.
    Citations:    Fields:    
  5. Grahn THM, Niroula A, Végvári Á, Oburoglu L, Pertesi M, Warsi S, Safi F, Miharada N, Garcia SC, Siva K, Liu Y, Rörby E, Nilsson B, Zubarev RA, Karlsson S. S100A6 is a critical regulator of hematopoietic stem cells. Leukemia. 2020 12; 34(12):3323-3337. PMID: 32555370.
    Citations: 1     Fields:    
  6. Miller PG, Niroula A, Ceremsak JJ, Gibson CJ, Taylor MS, Birndt S, Perner F, Arnason J, Sperling AS, Agrawal M, Schram AM, Nikiforow S, Pihan G, Hasserjian RP, Aster JC, La Rosée P, Morgan EA, Berliner N, Ebert BL. Identification of germline variants in adults with hemophagocytic lymphohistiocytosis. Blood Adv. 2020 03 10; 4(5):925-929. PMID: 32150605.
    Citations:    Fields:    
  7. Niroula A, Ajore R, Nilsson B. MPRAscore: robust and non-parametric analysis of massively parallel reporter assays. Bioinformatics. 2019 12 15; 35(24):5351-5353. PMID: 31359027.
    Citations: 1     Fields:    
  8. Yang Y, Ding X, Zhu G, Niroula A, Lv Q, Vihinen M. ProTstab - predictor for cellular protein stability. BMC Genomics. 2019 Nov 04; 20(1):804. PMID: 31684883.
    Citations: 1     Fields:    Translation:HumansCells
  9. Niroula A, Vihinen M. How good are pathogenicity predictors in detecting benign variants? PLoS Comput Biol. 2019 02; 15(2):e1006481. PMID: 30742610.
    Citations: 11     Fields:    Translation:Humans
  10. Ali M, Ajore R, Wihlborg AK, Niroula A, Swaminathan B, Johnsson E, Stephens OW, Morgan G, Meissner T, Turesson I, Goldschmidt H, Mellqvist UH, Gullberg U, Hansson M, Hemminki K, Nahi H, Waage A, Weinhold N, Nilsson B. The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression. Nat Commun. 2018 04 25; 9(1):1649. PMID: 29695719.
    Citations: 5     Fields:    Translation:HumansCells
  11. Yang Y, Urolagin S, Niroula A, Ding X, Shen B, Vihinen M. PON-tstab: Protein Variant Stability Predictor. Importance of Training Data Quality. Int J Mol Sci. 2018 Mar 28; 19(4). PMID: 29597263.
    Citations: 10     Fields:    
  12. Daneshjou R, Wang Y, Bromberg Y, Bovo S, Martelli PL, Babbi G, Lena PD, Casadio R, Edwards M, Gifford D, Jones DT, Sundaram L, Bhat RR, Li X, Pal LR, Kundu K, Yin Y, Moult J, Jiang Y, Pejaver V, Pagel KA, Li B, Mooney SD, Radivojac P, Shah S, Carraro M, Gasparini A, Leonardi E, Giollo M, Ferrari C, Tosatto SCE, Bachar E, Azaria JR, Ofran Y, Unger R, Niroula A, Vihinen M, Chang B, Wang MH, Franke A, Petersen BS, Pirooznia M, Zandi P, McCombie R, Potash JB, Altman RB, Klein TE, Hoskins RA, Repo S, Brenner SE, Morgan AA. Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges. Hum Mutat. 2017 09; 38(9):1182-1192. PMID: 28634997.
    Citations: 9     Fields:    Translation:Humans
  13. Carraro M, Minervini G, Giollo M, Bromberg Y, Capriotti E, Casadio R, Dunbrack R, Elefanti L, Fariselli P, Ferrari C, Gough J, Katsonis P, Leonardi E, Lichtarge O, Menin C, Martelli PL, Niroula A, Pal LR, Repo S, Scaini MC, Vihinen M, Wei Q, Xu Q, Yang Y, Yin Y, Zaucha J, Zhao H, Zhou Y, Brenner SE, Moult J, Tosatto SCE. Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI. Hum Mutat. 2017 09; 38(9):1042-1050. PMID: 28440912.
    Citations: 4     Fields:    Translation:HumansCells
  14. Niroula A, Vihinen M. PON-P and PON-P2 predictor performance in CAGI challenges: Lessons learned. Hum Mutat. 2017 09; 38(9):1085-1091. PMID: 28224672.
    Citations: 2     Fields:    Translation:Humans
  15. Halvarsson BM, Wihlborg AK, Ali M, Lemonakis K, Johnsson E, Niroula A, Cibulskis C, Weinhold N, Försti A, Alici E, Langer C, Pfreundschuh M, Goldschmidt H, Mellqvist UH, Turesson I, Waage A, Hemminki K, Golub T, Nahi H, Gullberg U, Hansson M, Nilsson B. Direct evidence for a polygenic etiology in familial multiple myeloma. Blood Adv. 2017 Apr 11; 1(10):619-623. PMID: 29296704.
    Citations: 8     Fields:    
  16. Niroula A, Vihinen M. Predicting Severity of Disease-Causing Variants. Hum Mutat. 2017 04; 38(4):357-364. PMID: 28070986.
    Citations: 9     Fields:    Translation:Humans
  17. Niroula A, Vihinen M. Variation Interpretation Predictors: Principles, Types, Performance, and Choice. Hum Mutat. 2016 06; 37(6):579-97. PMID: 26987456.
    Citations: 36     Fields:    Translation:Humans
  18. Yang Y, Niroula A, Shen B, Vihinen M. PON-Sol: prediction of effects of amino acid substitutions on protein solubility. Bioinformatics. 2016 07 01; 32(13):2032-4. PMID: 27153720.
    Citations: 9     Fields:    Translation:Humans
  19. Niroula A, Vihinen M. PON-mt-tRNA: a multifactorial probability-based method for classification of mitochondrial tRNA variations. Nucleic Acids Res. 2016 Mar 18; 44(5):2020-7. PMID: 26843426.
    Citations: 11     Fields:    Translation:HumansCells
  20. Niroula A, Vihinen M. Classification of Amino Acid Substitutions in Mismatch Repair Proteins Using PON-MMR2. Hum Mutat. 2015 Dec; 36(12):1128-34. PMID: 26333163.
    Citations: 8     Fields:    Translation:HumansCells
  21. Niroula A, Vihinen M. Harmful somatic amino acid substitutions affect key pathways in cancers. BMC Med Genomics. 2015 Aug 19; 8:53. PMID: 26282678.
    Citations: 6     Fields:    Translation:Humans
  22. Niroula A, Urolagin S, Vihinen M. PON-P2: prediction method for fast and reliable identification of harmful variants. PLoS One. 2015; 10(2):e0117380. PMID: 25647319.
    Citations: 52     Fields:    Translation:Humans
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: FAS faculty should contact the Office for Scholarly Communication (oschulmail.harvard.edu) for general questions about Profiles. For data questions, please contact Raelyn Lincoln (raelyn_lincolnharvard.edu) from the FAS Division of Science; Jennifer Shephard (jmshephfas.harvard.edu) from the FAS Division of Social Science; or Alexander Parker (afparkerfas.harvard.edu) from the FAS Division of Arts and Humanities.
Niroula's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (73)
Co-Authors (35)
Similar People (60)
Same Department 
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.