Harvard Catalyst Profiles

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Tim Moors, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Moors TE, Mona D, Luehe S, Duran-Pacheco G, Spycher L, Mundigl O, Kaluza K, Huber S, Hug MN, Kremer T, Ritter M, Dziadek S, Dernick G, van de Berg WDJ, Britschgi M. Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies. Acta Neuropathol Commun. 2022 06 03; 10(1):82. PMID: 35659116; PMCID: PMC9164351.
    Citations:    Fields:    Translation:Humans
  2. Glajch KE, Moors TE, Chen Y, Bechade PA, Nam AY, Rajsombath MM, McCaffery TD, Dettmer U, Weihofen A, Hirst WD, Selkoe DJ, Nuber S. Wild-type GBA1 increases the a-synuclein tetramer-monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in mice. Proc Natl Acad Sci U S A. 2021 08 03; 118(31). PMID: 34326260; PMCID: PMC8346893.
    Citations: 2     Fields:    Translation:Animals
  3. Moors TE, Maat CA, Niedieker D, Mona D, Petersen D, Timmermans-Huisman E, Kole J, El-Mashtoly SF, Spycher L, Zago W, Barbour R, Mundigl O, Kaluza K, Huber S, Hug MN, Kremer T, Ritter M, Dziadek S, Geurts JJG, Gerwert K, Britschgi M, van de Berg WDJ. The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy. Acta Neuropathol. 2021 09; 142(3):423-448. PMID: 34115198; PMCID: PMC8357756.
    Citations: 11     Fields:    Translation:HumansCells
  4. Tran HT, Tsai EHR, Lewis AJ, Moors T, Bol JGJM, Rostami I, Diaz A, Jonker AJ, Guizar-Sicairos M, Raabe J, Stahlberg H, van de Berg WDJ, Holler M, Shahmoradian SH. Alterations in Sub-Axonal Architecture Between Normal Aging and Parkinson's Diseased Human Brains Using Label-Free Cryogenic X-ray Nanotomography. Front Neurosci. 2020; 14:570019. PMID: 33324142.
  5. Shahmoradian SH, Lewis AJ, Genoud C, Hench J, Moors TE, Navarro PP, Castaño-Díez D, Schweighauser G, Graff-Meyer A, Goldie KN, Sütterlin R, Huisman E, Ingrassia A, Gier Y, Rozemuller AJM, Wang J, Paepe A, Erny J, Staempfli A, Hoernschemeyer J, Großerüschkamp F, Niedieker D, El-Mashtoly SF, Quadri M, Van IJcken WFJ, Bonifati V, Gerwert K, Bohrmann B, Frank S, Britschgi M, Stahlberg H, Van de Berg WDJ, Lauer ME. Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes. Nat Neurosci. 2019 07; 22(7):1099-1109. PMID: 31235907.
    Citations: 233     Fields:    Translation:HumansCells
  6. Gündner AL, Duran-Pacheco G, Zimmermann S, Ruf I, Moors T, Baumann K, Jagasia R, van de Berg WDJ, Kremer T. Path mediation analysis reveals GBA impacts Lewy body disease status by increasing a-synuclein levels. Neurobiol Dis. 2019 01; 121:205-213. PMID: 30236861.
    Citations: 17     Fields:    Translation:Humans
  7. Moors TE, Paciotti S, Ingrassia A, Quadri M, Breedveld G, Tasegian A, Chiasserini D, Eusebi P, Duran-Pacheco G, Kremer T, Calabresi P, Bonifati V, Parnetti L, Beccari T, van de Berg WDJ. Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson's Disease and Dementia with Lewy Bodies. Mol Neurobiol. 2019 Feb; 56(2):1344-1355. PMID: 29948939.
    Citations: 47     Fields:    Translation:HumansCells
  8. Tasegian A, Paciotti S, Ceccarini MR, Codini M, Moors T, Chiasserini D, Albi E, Winchester B, van de Berg WDJ, Parnetti L, Beccari T. Origin of a-mannosidase activity in CSF. Int J Biochem Cell Biol. 2017 06; 87:34-37. PMID: 28359775.
    Citations: 2     Fields:    Translation:Humans
  9. Moors TE, Hoozemans JJ, Ingrassia A, Beccari T, Parnetti L, Chartier-Harlin MC, van de Berg WD. Therapeutic potential of autophagy-enhancing agents in Parkinson's disease. Mol Neurodegener. 2017 01 25; 12(1):11. PMID: 28122627.
    Citations: 86     Fields:    Translation:HumansAnimals
  10. Moors T, Paciotti S, Chiasserini D, Calabresi P, Parnetti L, Beccari T, van de Berg WD. Lysosomal Dysfunction and a-Synuclein Aggregation in Parkinson's Disease: Diagnostic Links. Mov Disord. 2016 06; 31(6):791-801. PMID: 26923732.
    Citations: 55     Fields:    Translation:Humans
  11. Doorn KJ, Moors T, Drukarch B, van de Berg WDj, Lucassen PJ, van Dam AM. Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson's disease patients. Acta Neuropathol Commun. 2014 Aug 07; 2:90. PMID: 25099483.
    Citations: 112     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.