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Akos Jozsef Nyerges, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Nyerges A, Vinke S, Flynn R, Owen SV, Rand EA, Budnik B, Keen E, Narasimhan K, Marchand JA, Baas-Thomas M, Liu M, Chen K, Chiappino-Pepe A, Hu F, Baym M, Church GM. A swapped genetic code prevents viral infections and gene transfer. Nature. 2023 Mar 15. PMID: 36922599.
    Citations:    
  2. Apjok G, Számel M, Christodoulou C, Seregi V, Vásárhelyi BM, Stirling T, Eszenyi B, Sári T, Vidovics F, Nagrand E, Kovács D, Szili P, Lantos II, Méhi O, Jangir PK, Herczeg R, Gálik B, Urbán P, Gyenesei A, Draskovits G, Nyerges Á, Fekete G, Bodai L, Zsindely N, Dénes B, Yosef I, Qimron U, Papp B, Pál C, Kintses B. Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains. Nat Microbiol. 2023 Mar; 8(3):410-423. PMID: 36759752.
    Citations:    
  3. Shukla RD, Zvara Á, Avramucz Á, Biketova AY, Nyerges A, Puskás LG, Fehér T. inPOSE: A Flexible Toolbox for Chromosomal Cloning and Amplification of Bacterial Transgenes. Microorganisms. 2022 Jan 21; 10(2). PMID: 35208691.
    Citations:    
  4. Al-Ramahi Y, Nyerges A, Margolles Y, Cerdán L, Ferenc G, Pál C, Fernández LÁ, de Lorenzo V. ssDNA recombineering boosts in vivo evolution of nanobodies displayed on bacterial surfaces. Commun Biol. 2021 Oct 07; 4(1):1169. PMID: 34621006.
    Citations:    
  5. Apjok G, Boross G, Nyerges Á, Fekete G, Lázár V, Papp B, Pál C, Csörgo B. Corrigendum to: Limited evolutionary conservation of multidrug resistance and collateral sensitivity. Mol Biol Evol. 2021 Jun 25; 38(7):3029. PMID: 34010424.
    Citations:    
  6. Durcik M, Nyerges Á, Skok Ž, Skledar DG, Trontelj J, Zidar N, Ilaš J, Zega A, Cruz CD, Tammela P, Welin M, Kimbung YR, Focht D, Benek O, Révész T, Draskovits G, Szili PÉ, Daruka L, Pál C, Kikelj D, Mašic LP, Tomašic T. New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens. Eur J Med Chem. 2021 Mar 05; 213:113200. PMID: 33524686.
    Citations:    
  7. Wannier TM, Ciaccia PN, Ellington AD, Filsinger GT, Isaacs FJ, Javanmardi K, Jones MA, Kunjapur AM, Nyerges A, Pal C, Schubert MG, Church GM. Recombineering and MAGE. Nat Rev Methods Primers. 2021; 1. PMID: 35540496; PMCID: PMC9083505.
    Citations: 3     
  8. Durcik M, Skok Ž, Ilaš J, Zidar N, Zega A, Szili PÉ, Draskovits G, Révész T, Kikelj D, Nyerges A, Pál C, Mašic LP, Tomašic T. Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation. Pharmaceutics. 2020 Dec 22; 13(1). PMID: 33374964.
    Citations:    
  9. Nyerges A, Tomašic T, Durcik M, Revesz T, Szili P, Draskovits G, Bogar F, Skok Ž, Zidar N, Ilaš J, Zega A, Kikelj D, Daruka L, Kintses B, Vasarhelyi B, Foldesi I, Kata D, Welin M, Kimbung R, Focht D, Mašic LP, Pal C. Rational design of balanced dual-targeting antibiotics with limited resistance. PLoS Biol. 2020 Oct; 18(10):e3000819. PMID: 33017402.
    Citations:    
  10. Csörgo B, Nyerges A, Pál C. Targeted mutagenesis of multiple chromosomal regions in microbes. Curr Opin Microbiol. 2020 Oct; 57:22-30. PMID: 32599531.
    Citations:    
  11. Wannier TM, Nyerges A, Kuchwara HM, Czikkely M, Balogh D, Filsinger GT, Borders NC, Gregg CJ, Lajoie MJ, Rios X, Pál C, Church GM. Improved bacterial recombineering by parallelized protein discovery. Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13689-13698. PMID: 32467157.
    Citations: 13     Fields:    Translation:Cells
  12. Aparicio T, Nyerges A, Martínez-García E, de Lorenzo V. High-Efficiency Multi-site Genomic Editing of Pseudomonas putida through Thermoinducible ssDNA Recombineering. iScience. 2020 Mar 27; 23(3):100946. PMID: 32179472.
    Citations:    
  13. Lamut A, Skok Ž, Barancoková M, Gutierrez LJ, Cruz CD, Tammela P, Draskovits G, Szili PÉ, Nyerges Á, Pál C, Molek P, Bratkovic T, Ilaš J, Zidar N, Zega A, Enriz RD, Kikelj D, Tomašic T. Second-generation 4,5,6,7-tetrahydrobenzo[d]thiazoles as novel DNA gyrase inhibitors. Future Med Chem. 2020 Feb; 12(4):277-297. PMID: 32043377.
    Citations:    
  14. Hueso-Gil A, Nyerges Á, Pál C, Calles B, de Lorenzo V. Multiple-Site Diversification of Regulatory Sequences Enables Interspecies Operability of Genetic Devices. ACS Synth Biol. 2020 Jan 17; 9(1):104-114. PMID: 31794196.
    Citations:    
  15. Fois B, Skok Ž, Tomašic T, Ilaš J, Zidar N, Zega A, Peterlin Mašic L, Szili P, Draskovits G, Nyerges Á, Pál C, Kikelj D. Dual Escherichia coli DNA Gyrase A and B Inhibitors with Antibacterial Activity. ChemMedChem. 2020 Feb 05; 15(3):265-269. PMID: 31721445.
    Citations:    
  16. Aparicio T, Nyerges A, Nagy I, Pal C, Martínez-García E, de Lorenzo V. Mismatch repair hierarchy of Pseudomonas putida revealed by mutagenic ssDNA recombineering of the pyrF gene. Environ Microbiol. 2020 Jan; 22(1):45-58. PMID: 31599106.
    Citations:    
  17. Szili P, Draskovits G, Révész T, Bogár F, Balogh D, Martinek T, Daruka L, Spohn R, Vásárhelyi BM, Czikkely M, Kintses B, Grézal G, Ferenc G, Pál C, Nyerges Á. Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations. Antimicrob Agents Chemother. 2019 Sep; 63(9). PMID: 31235632.
    Citations:    
  18. Apjok G, Boross G, Nyerges Á, Fekete G, Lázár V, Papp B, Pál C, Csörgo B. Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations. Mol Biol Evol. 2019 Aug 01; 36(8):1601-1611. PMID: 31058961.
    Citations:    
  19. Guzmán GI, Sandberg TE, LaCroix RA, Nyerges Á, Papp H, de Raad M, King ZA, Hefner Y, Northen TR, Notebaart RA, Pál C, Palsson BO, Papp B, Feist AM. Enzyme promiscuity shapes adaptation to novel growth substrates. Mol Syst Biol. 2019 Apr 08; 15(4):e8462. PMID: 30962359.
    Citations:    
  20. Nyerges Á, Bálint B, Cseklye J, Nagy I, Pál C, Fehér T. CRISPR-interference-based modulation of mobile genetic elements in bacteria. Synth Biol (Oxf). 2019; 4(1):ysz008. PMID: 31008359.
    Citations:    
  21. Tiz DB, Skok Ž, Durcik M, Tomašic T, Mašic LP, Ilaš J, Zega A, Draskovits G, Révész T, Nyerges Á, Pál C, Cruz CD, Tammela P, Žigon D, Kikelj D, Zidar N. An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors. Eur J Med Chem. 2019 Apr 01; 167:269-290. PMID: 30776691.
    Citations:    
  22. Kintses B, Méhi O, Ari E, Számel M, Györkei Á, Jangir PK, Nagy I, Pál F, Fekete G, Tengölics R, Nyerges Á, Likó I, Bálint A, Molnár T, Bálint B, Vásárhelyi BM, Bustamante M, Papp B, Pál C. Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota. Nat Microbiol. 2019 Mar; 4(3):447-458. PMID: 30559406.
    Citations:    
  23. Nyerges Á, Csörgo B, Draskovits G, Kintses B, Szili P, Ferenc G, Révész T, Ari E, Nagy I, Bálint B, Vásárhelyi BM, Bihari P, Számel M, Balogh D, Papp H, Kalapis D, Papp B, Pál C. Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance. Proc Natl Acad Sci U S A. 2018 Jun 19; 115(25):E5726-E5735. PMID: 29871954.
    Citations:    
  24. Lázár V, Martins A, Spohn R, Daruka L, Grézal G, Fekete G, Számel M, Jangir PK, Kintses B, Csörgo B, Nyerges Á, Györkei Á, Kincses A, Dér A, Walter FR, Deli MA, Urbán E, Hegedus Z, Olajos G, Méhi O, Bálint B, Nagy I, Martinek TA, Papp B, Pál C. Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides. Nat Microbiol. 2018 Jun; 3(6):718-731. PMID: 29795541.
    Citations:    
  25. Durcik M, Lovison D, Skok Ž, Durante Cruz C, Tammela P, Tomašic T, Benedetto Tiz D, Draskovits G, Nyerges Á, Pál C, Ilaš J, Peterlin Mašic L, Kikelj D, Zidar N. New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity. Eur J Med Chem. 2018 Jun 25; 154:117-132. PMID: 29778894.
    Citations:    
  26. Ricaurte DE, Martínez-García E, Nyerges Á, Pál C, de Lorenzo V, Aparicio T. A standardized workflow for surveying recombinases expands bacterial genome-editing capabilities. Microb Biotechnol. 2018 Jan; 11(1):176-188. PMID: 29094478.
    Citations:    
  27. Bódi Z, Farkas Z, Nevozhay D, Kalapis D, Lázár V, Csörgo B, Nyerges Á, Szamecz B, Fekete G, Papp B, Araújo H, Oliveira JL, Moura G, Santos MAS, Székely T, Balázsi G, Pál C. Correction: Phenotypic heterogeneity promotes adaptive evolution. PLoS Biol. 2017 Jun; 15(6):e1002607. PMID: 28632738.
    Citations:    
  28. Bódi Z, Farkas Z, Nevozhay D, Kalapis D, Lázár V, Csörgo B, Nyerges Á, Szamecz B, Fekete G, Papp B, Araújo H, Oliveira JL, Moura G, Santos MAS, Székely T, Balázsi G, Pál C. Phenotypic heterogeneity promotes adaptive evolution. PLoS Biol. 2017 May; 15(5):e2000644. PMID: 28486496.
    Citations:    
  29. Umenhoffer K, Draskovits G, Nyerges Á, Karcagi I, Bogos B, Tímár E, Csörgo B, Herczeg R, Nagy I, Fehér T, Pál C, Pósfai G. Genome-Wide Abolishment of Mobile Genetic Elements Using Genome Shuffling and CRISPR/Cas-Assisted MAGE Allows the Efficient Stabilization of a Bacterial Chassis. ACS Synth Biol. 2017 Aug 18; 6(8):1471-1483. PMID: 28426191.
    Citations:    
  30. Csörgo B, Nyerges Á, Pósfai G, Fehér T. System-level genome editing in microbes. Curr Opin Microbiol. 2016 Oct; 33:113-122. PMID: 27472027.
    Citations:    
  31. Nyerges Á, Csörgo B, Nagy I, Bálint B, Bihari P, Lázár V, Apjok G, Umenhoffer K, Bogos B, Pósfai G, Pál C. A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species. Proc Natl Acad Sci U S A. 2016 Mar 01; 113(9):2502-7. PMID: 26884157.
    Citations:    
  32. Méhi O, Bogos B, Csörgo B, Pál F, Nyerges A, Papp B, Pál C. Perturbation of iron homeostasis promotes the evolution of antibiotic resistance. Mol Biol Evol. 2014 Oct; 31(10):2793-804. PMID: 25063442.
    Citations:    
  33. Lázár V, Nagy I, Spohn R, Csörgo B, Györkei Á, Nyerges Á, Horváth B, Vörös A, Busa-Fekete R, Hrtyan M, Bogos B, Méhi O, Fekete G, Szappanos B, Kégl B, Papp B, Pál C. Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network. Nat Commun. 2014 Jul 08; 5:4352. PMID: 25000950.
    Citations:    
  34. Nyerges Á, Csorgo B, Nagy I, Latinovics D, Szamecz B, Pósfai G, Pál C. Conditional DNA repair mutants enable highly precise genome engineering. Nucleic Acids Res. 2014 Apr; 42(8):e62. PMID: 24500200.
    Citations:    
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