Harvard Catalyst Profiles

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Shuichi Mizuno, PH.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R03AR045793 (MIZUNO, SHUICHI) Sep 30, 1998 - Aug 31, 2002
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mizuno S, Kashiwa K, Kang JD. Molecular and histological characteristics of bovine caudal nucleus pulposus by combined changes in hydrostatic and osmotic pressures in vitro. J Orthop Res. 2019 Feb; 37(2):466-476. PMID: 30480329.
    Citations:    Fields:    
  2. Takada E, Mizuno S. Reproduction of Characteristics of Extracellular Matrices in Specific Longitudinal Depth Zone Cartilage within Spherical Organoids in Response to Changes in Osmotic Pressure. Int J Mol Sci. 2018 May 18; 19(5). PMID: 29783650.
    Citations:    Fields:    Translation:AnimalsCells
  3. Ogura T, Tsuchiya A, Minas T, Mizuno S. Optimization of Extracellular Matrix Synthesis and Accumulation by Human Articular Chondrocytes in 3-Dimensional Construct with Repetitive Hydrostatic Pressure. Cartilage. 2018 04; 9(2):192-201. PMID: 29262701.
    Citations:    Fields:    Translation:HumansCells
  4. Mizuno S, Takada E, Fukai N. Spheroidal Organoids Reproduce Characteristics of Longitudinal Depth Zones in Bovine Articular Cartilage. Cells Tissues Organs. 2016; 202(5-6):382-392. PMID: 27654347.
    Citations: 1     Fields:    Translation:AnimalsCells
  5. Ogura T, Tsuchiya A, Minas T, Mizuno S. Methods of high integrity RNA extraction from cell/agarose construct. BMC Res Notes. 2015 Nov 04; 8:644. PMID: 26537242; PMCID: PMC4632373.
    Citations:    Fields:    Translation:AnimalsCells
  6. Ogawa R, Orgill DP, Murphy GF, Mizuno S. Hydrostatic pressure-driven three-dimensional cartilage induction using human adipose-derived stem cells and collagen gels. Tissue Eng Part A. 2015 Jan; 21(1-2):257-66. PMID: 25060524.
    Citations: 3     Fields:    Translation:HumansCells
  7. Tatsumura M, Sakane M, Ochiai N, Mizuno S. Off-loading of cyclic hydrostatic pressure promotes production of extracellular matrix by chondrocytes. Cells Tissues Organs. 2013; 198(6):405-13. PMID: 24777062.
    Citations: 2     Fields:    Translation:AnimalsCells
  8. Glowacki J, Mizuno S, Kung J, Goff J, Epperly M, Dixon T, Wang H, Greenberger JS. Effects of mouse genotype on bone wound healing and irradiation-induced delay of healing. In Vivo. 2014 Mar-Apr; 28(2):189-96. PMID: 24632972.
    Citations: 1     Fields:    Translation:Animals
  9. Zhou S, Mizuno S, Glowacki J. Wnt pathway regulation by demineralized bone is approximated by both BMP-2 and TGF-ß1 signaling. J Orthop Res. 2013 Apr; 31(4):554-60. PMID: 23239467.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  10. Mizuno S, Ogawa R. Using changes in hydrostatic and osmotic pressure to manipulate metabolic function in chondrocytes. Am J Physiol Cell Physiol. 2011 Jun; 300(6):C1234-45. PMID: 21270297.
    Citations: 7     Fields:    Translation:AnimalsCells
  11. Mizuno S. Novel cell culture model using pure hydrostatic pressure and a semipermeable membrane pouch. Cell Transplant. 2011; 20(5):767-74. PMID: 21054931.
    Citations:    Fields:    Translation:AnimalsCells
  12. Ogawa R, Mizuno S. Cartilage regeneration using adipose-derived stem cells. Curr Stem Cell Res Ther. 2010 Jun; 5(2):129-32. PMID: 19941456.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  13. Manome Y, Mizuno S, Akiyama N, Fujioka K, Saito H, Hataba Y, Kobayashi T, Watanabe M. Three-dimensional cell culture of glioma and morphological comparison of four different human cell lines. Anticancer Res. 2010 Feb; 30(2):383-9. PMID: 20332443.
    Citations:    Fields:    Translation:HumansCells
  14. Ogawa R, Mizuno S, Murphy GF, Orgill DP. The effect of hydrostatic pressure on three-dimensional chondroinduction of human adipose-derived stem cells. Tissue Eng Part A. 2009 Oct; 15(10):2937-45. PMID: 19290804; PMCID: PMC2811056.
    Citations: 13     Fields:    Translation:HumansCells
  15. Glowacki J, Zhou S, Mizuno S. Mechanisms of osteoinduction/chondroinduction by demineralized bone. J Craniofac Surg. 2009 Mar; 20 Suppl 1:634-8. PMID: 19169155.
    Citations: 1     Fields:    Translation:HumansCells
  16. Glowacki J, Mizuno S. Collagen scaffolds for tissue engineering. Biopolymers. 2008 May; 89(5):338-44. PMID: 17941007.
    Citations: 97     Fields:    Translation:HumansAnimals
  17. Mizuno S. [Bioengineering for cartilage and intervertebral disc regeneration]. Clin Calcium. 2006 Dec; 16(12):2059-64. PMID: 17142938.
    Citations:    Fields:    Translation:Humans
  18. Watanabe S, Inagaki S, Kinouchi I, Takai H, Masuda Y, Mizuno S. Hydrostatic pressure/perfusion culture system designed and validated for engineering tissue. J Biosci Bioeng. 2005 Jul; 100(1):105-11. PMID: 16233859.
    Citations: 2     Fields:    
  19. Mizuno S. A novel method for assessing effects of hydrostatic fluid pressure on intracellular calcium: a study with bovine articular chondrocytes. Am J Physiol Cell Physiol. 2005 Feb; 288(2):C329-37. PMID: 15643052.
    Citations: 16     Fields:    Translation:AnimalsCells
  20. Mizuno S, Glowacki J. Low oxygen tension enhances chondroinduction by demineralized bone matrix in human dermal fibroblasts in vitro. Cells Tissues Organs. 2005; 180(3):151-8. PMID: 16260861.
    Citations: 6     Fields:    Translation:HumansCells
  21. Manome Y, Saeki N, Yoshinaga H, Watanabe M, Mizuno S. A culture device demonstrates that hydrostatic pressure increases mRNA of RGS5 in neuroblastoma and CHC1-L in lymphocytic cells. Cells Tissues Organs. 2003; 174(4):155-61. PMID: 14504426.
    Citations:    Fields:    Translation:HumansCells
  22. Mizuno S, Tateishi T, Ushida T, Glowacki J. Hydrostatic fluid pressure enhances matrix synthesis and accumulation by bovine chondrocytes in three-dimensional culture. J Cell Physiol. 2002 Dec; 193(3):319-27. PMID: 12384984.
    Citations: 19     Fields:    Translation:AnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.