Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Michael Tri Hoang Do, Ph.D.

Title
Institution
Department
Address
Phone

Biography
Harvard Medical School, Boston, MAPhD2004Neurobiology
Johns Hopkins University School of Medicine, Baltimore, MDPostdoc2011Neuroscience

Overview
Our lab asks how light drives functions that are as diverse as visual perception and setting of the internal body clock. We pose this question for different species to learn how visual mechanisms are tailored to distinct needs. Our research spans organizational levels and time scales, from molecules to circuits and from milliseconds to hours. We focus on the retina and brain, relying primarily on electrophysiological and optical techniques applied in vitro and in vivo.

Visual performance is remarkable. Perception can be elicited by a small number of photons, yet continues when light has intensified by many orders of magnitude. How is this dynamic range established? In cases of severe blindness where visual awareness is lost, light can still synchronize the body clock with the solar day. What are the origins of this robustness?

Such questions of system function apply throughout biology. Posing them in the visual system is advantageous because the input, light, is precisely controllable and the outputs, such as the patterns of impulses sent from the eye to the brain, are often given to quantification. Thus, the intervening operations and their suitability to the organism can be made especially clear.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01EY036430 (DO, MICHAEL TRI HOANG) Sep 30, 2024 - Aug 31, 2029
    NIH
    Neurophysiology of Melanopsin Photoreceptors
    Role: Principal Investigator
  2. R01EY036071 (DO, MICHAEL TRI HOANG) May 1, 2024 - Apr 30, 2029
    NIH
    Signal Generation and Processing in the Retinohypothalamic Pathway
    Role: Principal Investigator
  3. R01EY034089 (DO, MICHAEL TRI HOANG) Sep 1, 2022 - Jun 30, 2027
    NIH
    Downstream Actions of Biophysical Mechanisms in the Visual System
    Role: Principal Investigator
  4. R21EY032731 (DO, MICHAEL TRI HOANG) May 1, 2021 - Mar 31, 2023
    NIH
    Origins and Transformations of Signals for Circadian Regulation
    Role: Principal Investigator
  5. R01EY030628 (DO, MICHAEL TRI HOANG) Sep 1, 2019 - Aug 31, 2023
    NIH
    Neurophysiology of the Fovea
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Updating...
This operation might take several minutes to complete. Please do not close your browser.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Do's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (113)
Explore
_
Co-Authors (4)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.