Harvard Catalyst Profiles

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Narek Darabedian, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yarravarapu N, Konada RSR, Darabedian N, Pedowitz NJ, Krishnamurthy SN, Pratt MR, Kohler JJ. Exo-Enzymatic Addition of Diazirine-Modified Sialic Acid to Cell Surfaces Enables Photocrosslinking of Glycoproteins. Bioconjug Chem. 2022 05 18; 33(5):781-787. PMID: 35437982; PMCID: PMC9426361.
    Citations:    Fields:    
  2. Pedowitz NJ, Batt AR, Darabedian N, Pratt MR. MYPT1 O-GlcNAc modification regulates sphingosine-1-phosphate mediated contraction. Nat Chem Biol. 2021 02; 17(2):169-177. PMID: 32929277.
    Citations: 6     Fields:    Translation:AnimalsCells
  3. Darabedian N, Yang B, Ding R, Cutolo G, Zaro BW, Woo CM, Pratt MR. O-Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins. Front Chem. 2020; 8:318. PMID: 32411667; PMCID: PMC7198827.
    Citations: 6     
  4. Yang X, Forster ER, Darabedian N, Kim AT, Pratt MR, Shen A, Hang HC. Translation of Microbiota Short-Chain Fatty Acid Mechanisms Affords Anti-infective Acyl-Salicylic Acid Derivatives. ACS Chem Biol. 2020 05 15; 15(5):1141-1147. PMID: 32091869.
    Citations: 3     Fields:    Translation:HumansCells
  5. Darabedian N, Pratt MR. Identifying potentially O-GlcNAcylated proteins using metabolic labeling, bioorthogonal enrichment, and Western blotting. Methods Enzymol. 2019; 622:293-307. PMID: 31155058; PMCID: PMC6860911.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  6. Wang X, Magdziarz P, Enriquez E, Zhao W, Quan C, Darabedian N, Momand J, Zhou F. Surface plasmon resonance and cytotoxicity assays of drug efficacies predicted computationally to inhibit p53/MDM2 interaction. Anal Biochem. 2019 03 15; 569:53-58. PMID: 30721669; PMCID: PMC6942878.
    Citations:    Fields:    Translation:HumansCells
  7. Darabedian N, Chen TC, Molina H, Pratt MR, Schönthal AH. Bioorthogonal Profiling of a Cancer Cell Proteome Identifies a Large Set of 3-Bromopyruvate Targets beyond Glycolysis. ACS Chem Biol. 2018 11 16; 13(11):3054-3058. PMID: 30395437.
    Citations: 4     Fields:    Translation:HumansCells
  8. Darabedian N, Thompson JW, Chuh KN, Hsieh-Wilson LC, Pratt MR. Optimization of Chemoenzymatic Mass Tagging by Strain-Promoted Cycloaddition (SPAAC) for the Determination of O-GlcNAc Stoichiometry by Western Blotting. Biochemistry. 2018 10 09; 57(40):5769-5774. PMID: 30169966.
    Citations: 16     Fields:    Translation:Cells
  9. Walter LA, Batt AR, Darabedian N, Zaro BW, Pratt MR. Azide- and Alkyne-Bearing Metabolic Chemical Reporters of Glycosylation Show Structure-Dependent Feedback Inhibition of the Hexosamine Biosynthetic Pathway. Chembiochem. 2018 09 17; 19(18):1918-1921. PMID: 29979493.
    Citations: 3     Fields:    Translation:HumansCells
  10. Darabedian N, Gao J, Chuh KN, Woo CM, Pratt MR. The Metabolic Chemical Reporter 6-Azido-6-deoxy-glucose Further Reveals the Substrate Promiscuity of O-GlcNAc Transferase and Catalyzes the Discovery of Intracellular Protein Modification by O-Glucose. J Am Chem Soc. 2018 06 13; 140(23):7092-7100. PMID: 29771506; PMCID: PMC6540071.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  11. Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR. The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8. J Am Chem Soc. 2017 06 14; 139(23):7872-7885. PMID: 28528544; PMCID: PMC6225779.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  12. Chen D, Darabedian N, Li Z, Kai T, Jiang D, Zhou F. An improved Bathocuproine assay for accurate valence identification and quantification of copper bound by biomolecules. Anal Biochem. 2016 Mar 15; 497:27-35. PMID: 26743717.
    Citations: 6     Fields:    Translation:Cells
  13. Yi X, Zhang Y, Gong M, Yu X, Darabedian N, Zheng J, Zhou F. Ca(2+) Interacts with Glu-22 of Aß(1-42) and Phospholipid Bilayers to Accelerate the Aß(1-42) Aggregation Below the Critical Micelle Concentration. Biochemistry. 2015 Oct 20; 54(41):6323-32. PMID: 26426973.
    Citations: 4     Fields:    Translation:Humans
  14. Jiang D, Darabedian N, Ghazarian S, Hao Y, Zhgamadze M, Majaryan N, Shen R, Zhou F. Dyes and Redox Couples with Matched Energy Levels: Elimination of the Dye-Regeneration Energy Loss in Dye-Sensitized Solar Cells. Chemphyschem. 2015 Nov 16; 16(16):3385-8. PMID: 26314383.
    Citations:    Fields:    
  15. Candelario M, Cuellar E, Reyes-Ruiz JM, Darabedian N, Feimeng Z, Miledi R, Russo-Neustadt A, Limon A. Direct evidence for GABAergic activity of Withania somnifera on mammalian ionotropic GABAA and GABA? receptors. J Ethnopharmacol. 2015 Aug 02; 171:264-72. PMID: 26068424.
    Citations: 15     Fields:    Translation:AnimalsCells
  16. He Y, Liu M, Darabedian N, Liang Y, Wu D, Xiang J, Zhou F. pH-dependent coordination of Pb2+ to metallothionein2: structures and insight into lead detoxification. Inorg Chem. 2014 Mar 17; 53(6):2822-30. PMID: 24559479.
    Citations: 3     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.