Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Jianren Mao, Ph.D., M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01NS126187 (Lei Xu; Jianren Mao) Dec 1, 2022 - Nov 30, 2027
    Co-Targeting IL-6 and EGFRsignaling for the Treatment of Schwannomatosis and Associated Pain
    Role Description: To provide novel mechanistic insights into the role of the tumor-neuron-macrophage cross-talk in pain response and the therapeutic intervention potential in Schwannomatosis models.
    Role: Co-Principal Investigator
  2. U24NS115689 (MAO, JIANREN) Sep 30, 2019 - Mar 31, 2024
    Specialized Clinical Center at MGH for the Early Phase Pain Investigation Clinical Network
    Role: Principal Investigator
  3. R01DA039925 (MAO, JIANREN) Sep 1, 2017 - Jul 31, 2021
    Combination Therapy with Opioid and Duloxetine for Chronic Pain Management
    Role: Principal Investigator
  4. R01DA036564 (MAO, JIANREN) Sep 15, 2013 - Dec 31, 2019
    Alleviating Opioid-Induced Hyperalgesia with Novel Pharmacotherapy
    Role: Principal Investigator
  5. R01DE022901 (MAO, JIANREN) Aug 1, 2012 - Jan 31, 2019
    A Model and Mechanism of the Comorbid Interaction between Pain and Anxiety
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ding W, Fischer L, Chen Q, Li Z, Yang L, You Z, Hu K, Wu X, Zhou X, Chao W, Hu P, Dagnew TM, Dubreuil DM, Wang S, Xia S, Bao C, Zhu S, Chen L, Wang C, Wainger B, Jin P, Mao J, Feng G, Harnett MT, Shen S. Highly synchronized cortical circuit dynamics mediate spontaneous pain in mice. J Clin Invest. 2023 Mar 01; 133(5). PMID: 36602876; PMCID: PMC9974100.
    Citations: 1     Fields:    
  2. Yin Z, Wu L, Zhang Y, Sun Y, Chen JW, Subudhi S, Ho W, Lee GY, Wang A, Gao X, Ren J, Zhu C, Zhang N, Ferraro GB, Muzikansky A, Zhang L, Stemmer-Rachamimov A, Mao J, Plotkin SR, Xu L. Co-Targeting IL-6 and EGFR signaling for the treatment of schwannomatosis and associated pain. bioRxiv. 2023 Feb 06. PMID: 36798353; PMCID: PMC9934519.
  3. Song C, Du XT, Hong YX, Mao JH, Zhang W. Association between social supports and negative emotions among pediatric residents in China: The chain-mediating role of psychological resilience and burnout. Front Public Health. 2022; 10:962259. PMID: 36755738; PMCID: PMC9899841.
    Citations:    Fields:    Translation:Humans
  4. Dai J, Kim H, You Z, McCabe MF, Zhang S, Wang S, Lim G, Chen L, Mao J. Role of 5-HT1A-mediated upregulation of brain indoleamine 2,3 dioxygenase 1 in the reduced antidepressant and antihyperalgesic effects of fluoxetine during maintenance treatment. Front Pharmacol. 2022; 13:1084108. PMID: 36588734; PMCID: PMC9800882.
  5. Hermann AL, Fell GL, Kemény LV, Fung CY, Held KD, Biggs PJ, Rivera PD, Bilbo SD, Igras V, Willers H, Kung J, Gheorghiu L, Hideghéty K, Mao J, Woolf CJ, Fisher DE. ß-Endorphin mediates radiation therapy fatigue. Sci Adv. 2022 Dec 16; 8(50):eabn6025. PMID: 36525492; PMCID: PMC9757747.
    Citations:    Fields:    
  6. Mao JH, Shen Y, Ruan Z, Xi XD. [Promoting Effect of Rat FVIII Light Chain Delivered by Adeno-Associated Virus Vector Serotype 8 on the Activity of Human FVIII Heavy Chain with Different Length]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2022 Dec; 30(6):1817-1823. PMID: 36476909.
    Citations:    Fields:    Translation:HumansAnimalsCells
  7. Ye Q, Wang DJ, Lan B, Mao JH. T-cell and B-cell repertoire diversity are selectively skewed in children with idiopathic nephrotic syndrome revealed by high-throughput sequencing. World J Pediatr. 2023 Mar; 19(3):273-282. PMID: 36449136.
    Citations:    Fields:    
  8. Ren Y, Zhou Y, You Z, Deng H, Kem WR, Mao J, Zhang W, Martyn JAJ. The nonopioid cholinergic agonist GTS-21 mitigates morphine-induced aggravation of burn injury pain together with inhibition of spinal microglia activation in young rats. Br J Anaesth. 2022 12; 129(6):959-969. PMID: 36243579.
    Citations:    Fields:    Translation:AnimalsCells
  9. Zhao JL, Qiao XH, Mao JH, Liu F, Fu HD. The interaction between cellular senescence and chronic kidney disease as a therapeutic opportunity. Front Pharmacol. 2022; 13:974361. PMID: 36091755; PMCID: PMC9459105.
  10. Yang L, Ding W, Dong Y, Chen C, Zeng Y, Jiang Z, Gan S, You Z, Zhao Y, Zhang Y, Ren X, Wang S, Dai J, Chen Z, Zhu S, Chen L, Shen S, Mao J, Xie Z. Electroacupuncture attenuates surgical pain-induced delirium-like behavior in mice via remodeling gut microbiota and dendritic spine. Front Immunol. 2022; 13:955581. PMID: 36003380; PMCID: PMC9393710.
    Citations: 1     Fields:    Translation:AnimalsCells
  11. Yuan B, Jiang C, Chen L, Wen L, Cui J, Chen M, Zhang S, Zhou L, Cai Y, Mao JH, Zou X, Hang B, Wang P. A Novel DNA Repair Gene Signature for Immune Checkpoint Inhibitor-Based Therapy in Gastric Cancer. Front Cell Dev Biol. 2022; 10:893546. PMID: 35676932; PMCID: PMC9168368.
  12. Yang Y, Tang LF, Hua CZ, Mao JH, Hong YX. Evaluation of a Novel Simulation Curriculum With the Segmented Model in Pediatric Cardiovascular Education. Front Public Health. 2022; 10:887405. PMID: 35669747; PMCID: PMC9163956.
    Citations:    Fields:    Translation:Humans
  13. Li L, Qiao X, Liu F, Wang J, Shen H, Fu H, Mao JH. Description of the Molecular and Phenotypic Spectrum of Lesch-Nyhan Disease in Eight Chinese Patients. Front Genet. 2022; 13:868942. PMID: 35559039; PMCID: PMC9086273.
  14. Li W, Li L, He L, Du Y, Fu HD, Peng ZY, Xiang WQ, Mao JH. Cytokine Gene Polymorphisms in Chinese Children with Idiopathic Nephrotic Syndrome. Iran J Immunol. 2022 Mar; 19(1):9. PMID: 35293350.
    Citations:    Fields:    Translation:Humans
  15. Wang JJ, Wang DJ, Fu HD, Wang DX, Yang Q, Peng XJ, Fu R, Yang HD, Zhang RF, Wang XW, Luan JW, Zhao F, Chen QX, Liang FF, Cao L, Zhang JJ, Li YJ, Dong Y, Huang HM, Bao Y, Shen XY, Zhou W, Cao GH, Liu CH, Jin YY, Ma ML, Jiang L, Shen Q, Xu H, Mao JH. Evaluation of a new frequency-volume chart for children with primary monosymptomatic nocturnal enuresis: a prospective, comparative study. World J Pediatr. 2021 Dec; 17(6):643-652. PMID: 34716893.
    Citations:    Fields:    Translation:Humans
  16. Wang Q, Zhang L, Zhang GW, Mao JH, Xi XD, Jiang L, Lv G, Lu J, Shen Y, Chen Z, Zhu J, Chen SJ. Inherent hepatocytic heterogeneity determines expression and retention of edited F9 alleles post-AAV/CRISPR infusion. Proc Natl Acad Sci U S A. 2021 10 19; 118(42). PMID: 34649996; PMCID: PMC8594492.
    Citations:    Fields:    Translation:Cells
  17. Liu F, Fu HD, Mao JH. Coronavirus disease 2019 vaccine for children in China: when to start? Mandatory or voluntary? Chin Med J (Engl). 2021 09 21; 134(24):3015-3016. PMID: 34561329; PMCID: PMC8710344.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  18. Chen L, Deng H, Houle T, Zhang Y, Ahmed S, Zhang W, Sullivan S, Opalacz A, Roth S, Filatava EJ, Stabach K, Vo T, Malarick C, Kim H, You Z, Shen S, Mao J. Comparison between acupuncture therapy and gabapentin for chronic pain: a pilot study. Acupunct Med. 2021 Dec; 39(6):619-628. PMID: 34325532.
    Citations:    Fields:    Translation:Humans
  19. Li W, Xiang WQ, Chen LY, Shang SQ, Mao JH. Correlation between infections with different glycoprotein H genotypes of human cytomegalovirus in children and hepatitis. Pediatr Neonatol. 2021 11; 62(6):658-660. PMID: 34348886.
    Citations:    Fields:    Translation:HumansCells
  20. Lin J, Huang LM, Wang JJ, Mao JH. Efficacy and safety of Huaiqihuang granule as adjuvant treatment for primary nephrotic syndrome in children: a meta-analysis and systematic review. World J Pediatr. 2021 Jun; 17(3):242-252. PMID: 34075551.
    Citations: 1     Fields:    Translation:Humans
  21. Robinson KC, Kemény LV, Fell GL, Hermann AL, Allouche J, Ding W, Yekkirala A, Hsiao JJ, Su MY, Theodosakis N, Kozak G, Takeuchi Y, Shen S, Berenyi A, Mao J, Woolf CJ, Fisher DE. Reduced MC4R signaling alters nociceptive thresholds associated with red hair. Sci Adv. 2021 04; 7(14). PMID: 33811065.
    Citations: 2     Fields:    Translation:Animals
  22. Ding W, You Z, Chen Q, Yang L, Doheny J, Zhou X, Li N, Wang S, Hu K, Chen L, Xia S, Wu X, Wang C, Zhang C, Chen L, Ritchie C, Huang P, Mao J, Shen S. Gut Microbiota Influences Neuropathic Pain Through Modulating Proinflammatory and Anti-inflammatory T Cells. Anesth Analg. 2021 04 01; 132(4):1146-1155. PMID: 32889847.
    Citations: 10     Fields:    Translation:AnimalsCells
  23. Zhang Y, Chen T, Zhang Y, Hu Q, Wang X, Chang H, Mao JH, Snijders AM, Xia Y. Contribution of trace element exposure to gestational diabetes mellitus through disturbing the gut microbiome. Environ Int. 2021 08; 153:106520. PMID: 33774496; PMCID: PMC8638703.
    Citations: 3     Fields:    Translation:Humans
  24. Feng M, Wang Y, Bi L, Zhang P, Wang H, Zhao Z, Mao JH, Wei G. CRL4ADTL degrades DNA-PKcs to modulate NHEJ repair and induce genomic instability and subsequent malignant transformation. Oncogene. 2021 03; 40(11):2096-2111. PMID: 33627782; PMCID: PMC7979543.
    Citations: 1     Fields:    Translation:HumansCells
  25. Huang LM, Mao JH. Glomerular podocyte dysfunction in inherited renal tubular disease. World J Pediatr. 2021 Jun; 17(3):227-233. PMID: 33625696.
    Citations:    Fields:    Translation:HumansCells
  26. Zhong C, He L, Lee SY, Chang H, Zhang Y, Threadgill DW, Yuan Y, Zhou F, Celniker SE, Xia Y, Snijders AM, Mao JH. Host genetics and gut microbiota cooperatively contribute to azoxymethane-induced acute toxicity in Collaborative Cross mice. Arch Toxicol. 2021 03; 95(3):949-958. PMID: 33458792.
    Citations:    Fields:    Translation:Animals
  27. Zhou Y, Leung-Pitt Y, Deng H, Ren Y, You Z, Kem WR, Shen S, Zhang W, Mao J, Martyn JAJ. Nonopioid GTS-21 Mitigates Burn Injury Pain in Rats by Decreasing Spinal Cord Inflammatory Responses. Anesth Analg. 2021 01; 132(1):240-252. PMID: 33264122; PMCID: PMC7736563.
    Citations: 2     Fields:    Translation:Animals
  28. Zhu L, Wang H, Jiang C, Li W, Zhai S, Cai X, Wang X, Liao L, Tao F, Jin D, Chen G, Xia Y, Mao JH, Li B, Wang P, Hang B. Clinically applicable 53-Gene prognostic assay predicts chemotherapy benefit in gastric cancer: A multicenter study. EBioMedicine. 2020 Nov; 61:103023. PMID: 33069062.
    Citations: 4     Fields:    Translation:HumansCells
  29. Quaye A, Potter K, Roth S, Acampora G, Mao J, Zhang Y. Perioperative Continuation of Buprenorphine at Low-Moderate Doses Was Associated with Lower Postoperative Pain Scores and Decreased Outpatient Opioid Dispensing Compared with Buprenorphine Discontinuation. Pain Med. 2020 09 01; 21(9):1955-1960. PMID: 32167541.
    Citations: 4     Fields:    Translation:Humans
  30. Garibyan L, Moradi Tuchayi S, Wang Y, Khodorova A, Stemmer-Rachamimov A, Purschke M, Osseiran S, Evans CL, Mao J, Strichartz G, Anderson RR. Neural Selective Cryoneurolysis with Ice Slurry Injection in a Rat Model. Anesthesiology. 2020 07; 133(1):185-194. PMID: 31977524; PMCID: PMC7299828.
    Citations: 1     Fields:    Translation:AnimalsCells
  31. Lu C, Zhang Y, Qin Y, Xu Q, Zhou R, Cui Y, Zhu Y, Zhang X, Zhang J, Wei X, Wang M, Hang B, Mao JH, Snijders AM, Liu M, Hu Z, Shen H, Zhou Z, Guo X, Wu X, Wang X, Xia Y. Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis. J Med Genet. 2021 01; 58(1):56-65. PMID: 32376790.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  32. Mao JH, Kim YM, Zhou YX, Hu D, Zhong C, Chang H, Brislawn CJ, Fansler S, Langley S, Wang Y, Peisl BYL, Celniker SE, Threadgill DW, Wilmes P, Orr G, Metz TO, Jansson JK, Snijders AM. Genetic and metabolic links between the murine microbiome and memory. Microbiome. 2020 04 17; 8(1):53. PMID: 32299497.
    Citations: 19     Fields:    Translation:AnimalsCells
  33. Jin YY, Huang LM, Quan XF, Mao JH. Dent disease: classification, heterogeneity and diagnosis. World J Pediatr. 2021 Feb; 17(1):52-57. PMID: 32248351.
    Citations: 1     Fields:    Translation:Humans
  34. You Z, Ding W, Doheny JT, Shen S, Yang J, Yang L, Chen L, Zhu S, Mao J. Methylphenidate and Morphine Combination Therapy in a Rat Model of Chronic Pain. Anesth Analg. 2020 02; 130(2):518-524. PMID: 31206430; PMCID: PMC7646954.
    Citations: 1     Fields:    Translation:Animals
  35. Yin C, Lin X, Wang Y, Liu X, Xiao Y, Liu J, Snijders AM, Wei G, Mao JH, Zhang P. FAM83D promotes epithelial-mesenchymal transition, invasion and cisplatin resistance through regulating the AKT/mTOR pathway in non-small-cell lung cancer. Cell Oncol (Dordr). 2020 Jun; 43(3):395-407. PMID: 32006253.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  36. Tang W, Su Y, Yuan C, Zhang Y, Zhou L, Peng L, Wang P, Chen G, Li Y, Li H, Zhi Z, Chang H, Hang B, Mao JH, Snijders AM, Xia Y. Prospective study reveals a microbiome signature that predicts the occurrence of post-operative enterocolitis in Hirschsprung disease (HSCR) patients. Gut Microbes. 2020 07 03; 11(4):842-854. PMID: 31944159.
    Citations: 9     Fields:    Translation:HumansCells
  37. Miao J, Zhou X, Ding W, You Z, Doheny J, Mei W, Chen Q, Mao J, Shen S. Proliferator-Activated Receptor-Gamma Coactivator-1a Haploinsufficiency Promotes Pain Chronification After Burn Injury. Anesth Analg. 2020 01; 130(1):240-247. PMID: 30829673; PMCID: PMC6752970.
    Citations: 1     Fields:    Translation:AnimalsCells
  38. Ye Q, Zhang T, Mao JH. Haze facilitates sensitization to house dust mites in children. Environ Geochem Health. 2020 Jul; 42(7):2195-2203. PMID: 31858358.
    Citations: 2     Fields:    Translation:HumansAnimals
  39. Zhao Y, Yang SM, Jin YL, Xiong GW, Wang P, Snijders AM, Mao JH, Zhang XW, Hang B. A Robust Gene Expression Prognostic Signature for Overall Survival in High-Grade Serous Ovarian Cancer. J Oncol. 2019; 2019:3614207. PMID: 31885574; PMCID: PMC6925684.
    Citations: 3     
  40. Chen L, Deng H, Houle T, Zhang Y, Ahmed S, Zhang V, Sullivan S, Opalaze A, Roth S, Filatava EJ, St Clair K, Vo T, Malarick C, Kim H, You Z, Shen S, Mao J. A randomized trial to assess the immediate impact of acupuncture on quantitative sensory testing, pain, and functional status. Pain. 2019 11; 160(11):2456-2463. PMID: 31283555.
    Citations:    Fields:    Translation:Humans
  41. DiBenedetto DJ, Wawrzyniak KM, Finkelman M, Kulich RJ, Chen L, Schatman ME, Stone MT, Mao J. Relationships Between Opioid Dosing, Pain Severity, and Disability in a Community-Based Chronic Pain Population: An Exploratory Retrospective Analysis. Pain Med. 2019 11 01; 20(11):2155-2165. PMID: 30657983.
    Citations: 5     Fields:    Translation:Humans
  42. You Z, Ding W, Doheny JT, Yang J, Yang L, Lim G, Miao J, Chen L, Shen S, Mao J. Persistent Nociception Facilitates the Extinction of Morphine-Induced Conditioned Place Preference. Anesth Analg. 2019 09; 129(3):890-895. PMID: 31425234.
    Citations:    Fields:    Translation:Animals
  43. Zhu XJ, Wang JJ, Mao JH, Shu Q, Du LZ. Relationships of Cadmium, Lead, and Mercury Levels With Albuminuria in US Adults: Results From the National Health and Nutrition Examination Survey Database, 2009-2012. Am J Epidemiol. 2019 07 01; 188(7):1281-1287. PMID: 30874715.
    Citations: 3     Fields:    Translation:Humans
  44. Karhade AV, Ogink PT, Thio QCBS, Cha TD, Gormley WB, Hershman SH, Smith TR, Mao J, Schoenfeld AJ, Bono CM, Schwab JH. Development of machine learning algorithms for prediction of prolonged opioid prescription after surgery for lumbar disc herniation. Spine J. 2019 11; 19(11):1764-1771. PMID: 31185292.
    Citations: 17     Fields:    Translation:Humans
  45. Hung MS, Chen YC, Lin P, Li YC, Hsu CC, Lung JH, You L, Xu Z, Mao JH, Jablons DM, Yang CT. Cul4A Modulates Invasion and Metastasis of Lung Cancer Through Regulation of ANXA10. Cancers (Basel). 2019 May 02; 11(5). PMID: 31052599; PMCID: PMC6562482.
    Citations: 8     
  46. Ye Q, Shao WX, Wang QQ, Mao JH. An imbalance of T cell subgroups exists in children with sepsis. Microbes Infect. 2019 Oct - Nov; 21(8-9):386-392. PMID: 31009807.
    Citations: 1     Fields:    Translation:HumansCells
  47. Martyn JAJ, Mao J, Bittner EA. Opioid Tolerance in Critical Illness. N Engl J Med. 2019; 380. PMID: 31815254.
  48. Martyn JAJ, Mao J, Bittner EA. Opioid Tolerance in Critical Illness. Reply. N Engl J Med. 2019 04 18; 380(16):e26. PMID: 30995390.
    Citations:    Fields:    Translation:HumansCells
  49. Yang L, Ding W, You Z, Yang J, Shen S, Doheny JT, Chen L, Li R, Mao J. Alleviation of trigeminal neuropathic pain by electroacupuncture: the role of hyperpolarization-activated cyclic nucleotide-gated channel protein expression in the Gasserian ganglion. Acupunct Med. 2019 06; 37(3):192-198. PMID: 30977667.
    Citations:    Fields:    Translation:HumansAnimals
  50. Chen K, Luan X, Liu Q, Wang J, Chang X, Snijders AM, Mao JH, Secombe J, Dan Z, Chen JH, Wang Z, Dong X, Qiu C, Chang X, Zhang D, Celniker SE, Liu X. Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance. Cell Host Microbe. 2019 04 10; 25(4):537-552.e8. PMID: 30902578; PMCID: PMC6749836.
    Citations: 38     Fields:    Translation:HumansAnimals
  51. Karhade AV, Ogink PT, Thio QCBS, Broekman MLD, Cha TD, Hershman SH, Mao J, Peul WC, Schoenfeld AJ, Bono CM, Schwab JH. Machine learning for prediction of sustained opioid prescription after anterior cervical discectomy and fusion. Spine J. 2019 06; 19(6):976-983. PMID: 30710731.
    Citations: 18     Fields:    Translation:Humans
  52. Martyn JAJ, Mao J, Bittner EA. Opioid Tolerance in Critical Illness. N Engl J Med. 2019 01 24; 380(4):365-378. PMID: 30673555; PMCID: PMC6897318.
    Citations: 35     Fields:    Translation:HumansCells
  53. You Z, Ding W, Doheny JT, Yang J, Yang L, Lim G, Miao J, Chen L, Shen S, Mao J. Persistent Nociception Facilitates the Extinction of Morphine-Induced Conditioned Place Preference. Anesth Analg. 2018 Sep 27. PMID: 30273229.
    Citations:    Fields:    
  54. Lin Q, Mao JH. Early prediction of acute kidney injury in children: known biomarkers but novel combination. World J Pediatr. 2018 Dec; 14(6):617-620. PMID: 30112669.
    Citations:    Fields:    Translation:Humans
  55. Sun EC, Mao J, Anderson TA. Treating Chronic Pain: Is Buprenorphine the (or Even an) Answer? Anesth Analg. 2018 08; 127(2):336-337. PMID: 30028385; PMCID: PMC6579535.
    Citations: 1     Fields:    Translation:Humans
  56. You Z, Zhang S, Shen S, Yang J, Ding W, Yang L, Lim G, Doheny JT, Tate S, Chen L, Mao J. Cognitive impairment in a rat model of neuropathic pain: role of hippocampal microtubule stability. Pain. 2018 Aug; 159(8):1518-1528. PMID: 29613911; PMCID: PMC6053326.
    Citations: 12     Fields:    Translation:AnimalsCells
  57. Albrecht DS, Ahmed SU, Kettner NW, Borra RJH, Cohen-Adad J, Deng H, Houle TT, Opalacz A, Roth SA, Melo MFV, Chen L, Mao J, Hooker JM, Loggia ML, Zhang Y. Neuroinflammation of the spinal cord and nerve roots in chronic radicular pain patients. Pain. 2018 May; 159(5):968-977. PMID: 29419657.
    Citations: 39     Fields:    Translation:Humans
  58. Jin YY, Feng BY, Mao JH. The status quo and challenges of genetic diagnosis in children with steroid-resistant nephrotic syndrome. World J Pediatr. 2018 04; 14(2):105-109. PMID: 29644498.
    Citations: 1     Fields:    Translation:Humans
  59. Shen S, Ding W, Ahmed S, Hu R, Opalacz A, Roth S, You Z, Wotjkiewicz GR, Lim G, Chen L, Mao J, Chen JW, Zhang Y. Ultrasmall Superparamagnetic Iron Oxide Imaging Identifies Tissue and Nerve Inflammation in Pain Conditions. Pain Med. 2018 04 01; 19(4):686-692. PMID: 29177411; PMCID: PMC6659016.
    Citations: 1     Fields:    Translation:HumansAnimals
  60. Ye Q, Mao JH, Shu Q, Shang SQ. Mycoplasma pneumoniae induces allergy by producing P1-specific immunoglobulin E. Ann Allergy Asthma Immunol. 2018 07; 121(1):90-97. PMID: 29555351.
    Citations: 4     Fields:    Translation:HumansCells
  61. Liu F, Mao JH. Calcineurin inhibitors and nephrotoxicity in children. World J Pediatr. 2018 04; 14(2):121-126. PMID: 29532435.
    Citations: 4     Fields:    Translation:Humans
  62. Ding W, You Z, Shen S, Yang J, Lim G, Doheny JT, Zhu S, Zhang Y, Chen L, Mao J. Increased HCN Channel Activity in the Gasserian Ganglion Contributes to Trigeminal Neuropathic Pain. J Pain. 2018 06; 19(6):626-634. PMID: 29366880; PMCID: PMC5972061.
    Citations: 5     Fields:    Translation:Animals
  63. Chen EG, Wang P, Lou H, Wang Y, Yan H, Bi L, Liu L, Li B, Snijders AM, Mao JH, Hang B. A robust gene expression-based prognostic risk score predicts overall survival of lung adenocarcinoma patients. Oncotarget. 2018 Jan 23; 9(6):6862-6871. PMID: 29467935.
    Citations: 6     Fields:    
  64. Aiudi CM, Dunn RY, Burns SM, Roth SA, Opalacz A, Zhang Y, Chen L, Mao J, Ahmed SU. Loss of Efficacy to Spinal Cord Stimulator Therapy: Clinical Evidence and Possible Causes. Pain Physician. 2017 11; 20(7):E1073-E1080. PMID: 29149152.
    Citations: 7     Fields:    Translation:Humans
  65. Mi W, Wang S, You Z, Lim G, McCabe MF, Kim H, Chen L, Mao J. Nortriptyline Enhances Morphine-Conditioned Place Preference in Neuropathic Rats: Role of the Central Noradrenergic System. Anesth Analg. 2017 09; 125(3):1032-1041. PMID: 28537967; PMCID: PMC5561460.
    Citations: 2     Fields:    Translation:AnimalsCells
  66. Maher DP, Zhang Y, Ahmed S, Doshi T, Malarick C, Stabach K, Mao J, Chen L. Chronic Opioid Therapy Modifies QST Changes After Ketamine Infusion in Chronic Pain Patients. J Pain. 2017 12; 18(12):1468-1475. PMID: 28802882; PMCID: PMC5729746.
    Citations: 1     Fields:    Translation:Humans
  67. Maher DP, Ding W, Singh S, Opalacz A, Fishman C, Houghton M, Ahmed S, Chen L, Mao J, Zhang Y. Thermal QST Phenotypes Associated with Response to Lumbar Epidural Steroid Injections: A Pilot Study. Pain Med. 2017 Aug 01; 18(8):1455-1463. PMID: 28340251; PMCID: PMC6407608.
    Citations: 3     Fields:    Translation:Humans
  68. Shen S, Lim G, You Z, Ding W, Huang P, Ran C, Doheny J, Caravan P, Tate S, Hu K, Kim H, McCabe M, Huang B, Xie Z, Kwon D, Chen L, Mao J. Gut microbiota is critical for the induction of chemotherapy-induced pain. Nat Neurosci. 2017 Sep; 20(9):1213-1216. PMID: 28714953; PMCID: PMC5575957.
    Citations: 68     Fields:    Translation:AnimalsCells
  69. Li TX, Mao JH, Huang L, Fu HD, Chen SH, Liu AM, Liang YQ. Beneficial effects of Huaiqihuang on hyperglycemia-induced MPC5 podocyte dysfunction through the suppression of mitochondrial dysfunction and endoplasmic reticulum stress. Mol Med Rep. 2017 Aug; 16(2):1465-1471. PMID: 28627684.
    Citations: 6     Fields:    Translation:AnimalsCells
  70. Xu H, Li W, Mao JH, Pan YX. Association between red blood cell distribution width and Henoch-Schonlein purpura nephritis. Medicine (Baltimore). 2017 Jun; 96(23):e7091. PMID: 28591051; PMCID: PMC5466229.
    Citations: 4     Fields:    Translation:HumansCells
  71. Zhao SA, Ning BT, Mao JH. Clinical characteristics of children with hemolytic uremic syndrome in Hangzhou, China. World J Pediatr. 2017 Apr; 13(2):183-185. PMID: 28353273.
    Citations:    Fields:    Translation:Humans
  72. Yan H, Bi L, Wang Y, Zhang X, Hou Z, Wang Q, Snijders AM, Mao JH. Integrative analysis of multi-omics data reveals distinct impacts of DDB1-CUL4 associated factors in human lung adenocarcinomas. Sci Rep. 2017 03 23; 7(1):333. PMID: 28336923.
    Citations: 7     Fields:    Translation:Humans
  73. Ding W, You Z, Shen S, Yang J, Lim G, Doheny JT, Chen L, Zhu S, Mao J. An Improved Rodent Model of Trigeminal Neuropathic Pain by Unilateral Chronic Constriction Injury of Distal Infraorbital Nerve. J Pain. 2017 08; 18(8):899-907. PMID: 28238950; PMCID: PMC5537008.
    Citations: 18     Fields:    Translation:Animals
  74. Mao J. Challenges of managing chronic pain. BMJ. 2017 Feb 17; 356:j741. PMID: 28213344.
    Citations: 7     Fields:    Translation:Humans
  75. Wang Y, Zhang P, Wang Y, Zhan P, Liu C, Mao JH, Wei G. Distinct Interactions of EBP1 Isoforms with FBXW7 Elicits Different Functions in Cancer. Cancer Res. 2017 04 15; 77(8):1983-1996. PMID: 28209614; PMCID: PMC5392370.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  76. Mao JH, Huang QH, Liu P, Luo C, Xi XD. [Role and Mechanism of the Interaction of BCR-ABL with E3 Ligase c-CBL in Targeting Therapy of Chronic Myelogenous Leukemia]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017 Feb; 25(1):42-49. PMID: 28245373.
    Citations:    Fields:    Translation:HumansCells
  77. Maher DP, Chen L, Mao J. Intravenous Ketamine Infusions for Neuropathic Pain Management: A Promising Therapy in Need of Optimization. Anesth Analg. 2017 02; 124(2):661-674. PMID: 28067704.
    Citations: 16     Fields:    Translation:Humans
  78. Schaller SJ, Alam SM, Mao J, Zhao Y, Blobner M, Greenblatt DJ, Martyn JA. Pharmacokinetics cannot explain the increased effective dose requirement for morphine and midazolam in rats during their extended administration alone or in combination. J Pharm Pharmacol. 2017 Jan; 69(1):82-88. PMID: 27891611.
    Citations: 3     Fields:    Translation:Animals
  79. Jin YY, He MZ, Wu ZY, Huang K, Shen Y, Liang L, Mao JH. Dysregulation of calcium channels decreases parasecretion in pancreatic ß-cells in rats born small for gestational age. Growth Factors. 2016 12; 34(5-6):159-165. PMID: 27681688.
    Citations:    Fields:    Translation:HumansAnimalsCells
  80. Rusanescu G, Mao J. Peripheral nerve injury induces adult brain neurogenesis and remodelling. J Cell Mol Med. 2017 02; 21(2):299-314. PMID: 27665307; PMCID: PMC5264155.
    Citations: 12     Fields:    Translation:AnimalsCells
  81. Chen X, Spaeth RB, Freeman SG, Scarborough DM, Hashmi JA, Wey HY, Egorova N, Vangel M, Mao J, Wasan AD, Edwards RR, Gollub RL, Kong J. The Modulation Effect of Longitudinal Acupuncture on Resting State Functional Connectivity in Knee Osteoarthritis Patients. Mol Pain. 2015 01; 11. PMID: 27655921.
  82. Yue Y, Leung SG, Liu Y, Huang Y, Grundt K, Østvold AC, Jen KY, Schild D, Mao JH, Wiese C. Nucks1 synergizes with Trp53 to promote radiation lymphomagenesis in mice. Oncotarget. 2016 Sep 20; 7(38):61874-61889. PMID: 27542204.
    Citations: 5     Fields:    Translation:AnimalsCells
  83. Ding W, You Z, Shen S, Chen L, Zhu S, Mao J. Inhibition of HCN channel activity in the thalamus attenuates chronic pain in rats. Neurosci Lett. 2016 Sep 19; 631:97-103. PMID: 27542339.
    Citations: 5     Fields:    Translation:Animals
  84. Ye Q, Fu JF, Mao JH, Shang SQ. Haze is a risk factor contributing to the rapid spread of respiratory syncytial virus in children. Environ Sci Pollut Res Int. 2016 Oct; 23(20):20178-20185. PMID: 27439752.
    Citations: 36     Fields:    Translation:HumansCellsPHPublic Health
  85. Ye Q, Fu JF, Mao JH, Shen HQ, Chen XJ, Shao WX, Shang SQ, Wu YF. Haze is an important medium for the spread of rotavirus. Environ Pollut. 2016 Sep; 216:324-331. PMID: 27289527.
    Citations: 6     Fields:    Translation:HumansCells
  86. Xu H, Pan YX, Zhang J, Liu Y, Mao JH, Li W. Lack of Association between Interleukin-8 Gene +781 C/T Polymorphism and Henoch-Schönlein Purpura in Childhood. Iran J Allergy Asthma Immunol. 2016 Jun; 15(3):237-43. PMID: 27424139.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  87. Yao Y, Tan YH, Light AR, Mao J, Yu AC, Fu KY. Alendronate Attenuates Spinal Microglial Activation and Neuropathic Pain. J Pain. 2016 08; 17(8):889-903. PMID: 27063783.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  88. Hung MS, Chen IC, You L, Jablons DM, Li YC, Mao JH, Xu Z, Lung JH, Yang CT, Liu ST. Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells. J Cell Mol Med. 2016 07; 20(7):1295-306. PMID: 26969027; PMCID: PMC4929302.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  89. Wang JJ, Mao JH. The etiology of congenital nephrotic syndrome: current status and challenges. World J Pediatr. 2016 May; 12(2):149-58. PMID: 26961288.
    Citations: 12     Fields:    Translation:Humans
  90. Zheng XY, Xu J, Li W, Li SS, Shi CP, Zhao ZY, Mao JH, Chen X. Frosted Branch Angiitis in Pediatric Dyskeratosis Congenita: A Case Report. Medicine (Baltimore). 2016 Mar; 95(12):e3106. PMID: 27015183; PMCID: PMC4998378.
    Citations:    Fields:    Translation:Humans
  91. Ye Q, Shao WX, Shang SQ, Shen HQ, Chen XJ, Tang YM, Yu YL, Mao JH. Clinical Value of Assessing Cytokine Levels for the Differential Diagnosis of Bacterial Meningitis in a Pediatric Population. Medicine (Baltimore). 2016 Mar; 95(13):e3222. PMID: 27043692; PMCID: PMC4998553.
    Citations: 12     Fields:    Translation:Humans
  92. Zhang S, You Z, Wang S, Yang J, Yang L, Sun Y, Mi W, Yang L, McCabe MF, Shen S, Chen L, Mao J. Neuropeptide S modulates the amygdaloidal HCN activities (Ih) in rats: Implication in chronic pain. Neuropharmacology. 2016 06; 105:420-433. PMID: 26855147.
    Citations: 9     Fields:    Translation:AnimalsCells
  93. Lee CT, Vo TT, Cohen AS, Ahmed S, Zhang Y, Mao J, Chen L. Profiles of Urine Drug Test in Clinical Pain Patients vs Pain Research Study Subjects. Pain Med. 2016 Apr; 17(4):636-43. PMID: 26398237.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  94. Zhai X, Sun C, Rong P, Li S, McCabe MF, Wang X, Mao J, Wang S. A Correlative Relationship Between Chronic Pain and Insulin Resistance in Zucker Fatty Rats: Role of Downregulation of Insulin Receptors. J Pain. 2016 Apr; 17(4):404-13. PMID: 26705975.
    Citations: 8     Fields:    Translation:AnimalsCells
  95. Mao J. Clinical Diagnosis of Opioid-Induced Hyperalgesia. Reg Anesth Pain Med. 2015 Nov-Dec; 40(6):663-4. PMID: 26488079.
    Citations: 5     Fields:    Translation:Humans
  96. Chen X, Spaeth RB, Freeman SG, Scarborough DM, Hashmi JA, Wey HY, Egorova N, Vangel M, Mao J, Wasan AD, Edwards RR, Gollub RL, Kong J. The modulation effect of longitudinal acupuncture on resting state functional connectivity in knee osteoarthritis patients. Mol Pain. 2015 Oct 29; 11:67. PMID: 26511911.
    Citations: 35     Fields:    Translation:HumansCTClinical Trials
  97. Xu B, Chen M, Yao M, Ji X, Mao Z, Tang W, Qiao S, Schick SF, Mao JH, Hang B, Xia Y. Metabolomics reveals metabolic changes in male reproductive cells exposed to thirdhand smoke. Sci Rep. 2015 Oct 22; 5:15512. PMID: 26489853.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  98. Wen M, Kwon Y, Wang Y, Mao JH, Wei G. Elevated expression of UBE2T exhibits oncogenic properties in human prostate cancer. Oncotarget. 2015 Sep 22; 6(28):25226-39. PMID: 26308072.
    Citations: 39     Fields:    Translation:HumansCells
  99. Rusanescu G, Mao J. Immature spinal cord neurons are dynamic regulators of adult nociceptive sensitivity. J Cell Mol Med. 2015 Oct; 19(10):2352-64. PMID: 26223362; PMCID: PMC4594677.
    Citations: 4     Fields:    Translation:AnimalsCells
  100. Yang YL, Ni J, Hsu PC, Mao JH, Hsieh D, Xu A, Chan G, Au A, Xu Z, Jablons DM, You L. Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma. J Cell Mol Med. 2015 Oct; 19(10):2385-96. PMID: 26218750.
    Citations: 7     Fields:    Translation:HumansCells
  101. Bicket MC, Mao J. Chronic Pain in Older Adults. Anesthesiol Clin. 2015 Sep; 33(3):577-90. PMID: 26315639.
    Citations: 20     Fields:    Translation:Humans
  102. Jamison RN, Mao J. Opioid Analgesics. Mayo Clin Proc. 2015 Jul; 90(7):957-68. PMID: 26141334.
    Citations: 33     Fields:    Translation:HumansPHPublic Health
  103. Ahmed SU, Zhang Y, Chen L, Cohen A, St Hillary K, Vo T, Houghton M, Mao J. Effect of 1.5% Topical Diclofenac on Clinical Neuropathic Pain. Anesthesiology. 2015 Jul; 123(1):191-8. PMID: 25955980.
    Citations: 9     Fields:    Translation:Humans
  104. Ahmed SU, Zhang Y, Chen L, St Hillary K, Cohen A, Vo T, Houghton M, Mao J. Effects of Spinal Cord Stimulation on Pain Thresholds and Sensory Perceptions in Chronic Pain Patients. Neuromodulation. 2015 Jul; 18(5):355-60. PMID: 26033205.
    Citations: 5     Fields:    Translation:Humans
  105. Tsui JI, Lira MC, Cheng DM, Winter MR, Alford DP, Liebschutz JM, Mao J, Edwards RR, Samet JH. Hepatitis C virus infection and pain sensitivity in patients on methadone or buprenorphine maintenance therapy for opioid use disorders. Drug Alcohol Depend. 2015 Aug 01; 153:286-92. PMID: 26048638.
    Citations: 2     Fields:    Translation:Humans
  106. Ye Q, Shang SQ, Liu AM, Zhang T, Shen HQ, Chen XJ, Mao JH. 24h Urinary Protein Levels and Urine Protein/Creatinine Ratios Could Probably Forecast the Pathological Classification of HSPN. PLoS One. 2015; 10(5):e0127767. PMID: 25996387; PMCID: PMC4440756.
    Citations: 8     Fields:    Translation:HumansCells
  107. Blasi F, Herisson F, Wang S, Mao J, Ayata C. Late-onset thermal hypersensitivity after focal ischemic thalamic infarcts as a model for central post-stroke pain in rats. J Cereb Blood Flow Metab. 2015 Jul; 35(7):1100-3. PMID: 25899295; PMCID: PMC4640279.
    Citations: 6     Fields:    Translation:Animals
  108. You B, Yang YL, Xu Z, Dai Y, Liu S, Mao JH, Tetsu O, Li H, Jablons DM, You L. Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells. Oncotarget. 2015 Feb 28; 6(6):4357-68. PMID: 25738359; PMCID: PMC4414195.
    Citations: 48     Fields:    Translation:HumansCells
  109. Chen JY, Mao JH. Henoch-Schönlein purpura nephritis in children: incidence, pathogenesis and management. World J Pediatr. 2015 Feb; 11(1):29-34. PMID: 25557596.
    Citations: 34     Fields:    Translation:Humans
  110. Pan YX, Ye Q, Shao WX, Shang SQ, Mao JH, Zhang T, Shen HQ, Zhao N. Relationship between immune parameters and organ involvement in children with Henoch-Schonlein purpura. PLoS One. 2014; 9(12):e115261. PMID: 25514176; PMCID: PMC4267823.
    Citations: 17     Fields:    Translation:HumansCells
  111. Ueda M, Iwasaki H, Wang S, Murata E, Poon KY, Mao J, Martyn JA. Cannabinoid receptor type 1 antagonist, AM251, attenuates mechanical allodynia and thermal hyperalgesia after burn injury. Anesthesiology. 2014 Dec; 121(6):1311-9. PMID: 25188001; PMCID: PMC4237656.
    Citations: 7     Fields:    Translation:AnimalsCells
  112. Zhang Y, Ahmed S, Vo T, St Hilaire K, Houghton M, Cohen AS, Mao J, Chen L. Increased pain sensitivity in chronic pain subjects on opioid therapy: a cross-sectional study using quantitative sensory testing. Pain Med. 2015 May; 16(5):911-22. PMID: 25376890.
    Citations: 12     Fields:    Translation:Humans
  113. Chen L, Sein M, Vo T, Amhmed S, Zhang Y, Hilaire KS, Houghton M, Mao J. Clinical interpretation of opioid tolerance versus opioid-induced hyperalgesia. J Opioid Manag. 2014 Nov-Dec; 10(6):383-93. PMID: 25531956.
    Citations: 11     Fields:    Translation:Humans
  114. Rusanescu G, Mao J. Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord. J Cell Mol Med. 2014 Oct; 18(10):2103-16. PMID: 25164209.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  115. Yang L, Xin X, Zhang J, Zhang L, Dong Y, Zhang Y, Mao J, Xie Z. Inflammatory pain may induce cognitive impairment through an interlukin-6-dependent and postsynaptic density-95-associated mechanism. Anesth Analg. 2014 Aug; 119(2):471-480. PMID: 24878682; PMCID: PMC4107025.
    Citations: 8     Fields:    Translation:AnimalsCells
  116. Lim G, Kim H, McCabe MF, Chou CW, Wang S, Chen LL, Marota JJ, Blood A, Breiter HC, Mao J. A leptin-mediated central mechanism in analgesia-enhanced opioid reward in rats. J Neurosci. 2014 Jul 16; 34(29):9779-88. PMID: 25031415.
    Citations: 13     Fields:    Translation:AnimalsCells
  117. Fell GL, Robinson KC, Mao J, Woolf CJ, Fisher DE. Skin ß-endorphin mediates addiction to UV light. Cell. 2014 Jun 19; 157(7):1527-34. PMID: 24949966.
    Citations: 75     Fields:    Translation:HumansAnimals
  118. Zhang S, Jin X, You Z, Wang S, Lim G, Yang J, McCabe M, Li N, Marota J, Chen L, Mao J. Persistent nociception induces anxiety-like behavior in rodents: role of endogenous neuropeptide S. Pain. 2014 Aug; 155(8):1504-1515. PMID: 24793908.
    Citations: 14     Fields:    Translation:AnimalsCells
  119. Chen KY, Chen L, Mao J. Buprenorphine-naloxone therapy in pain management. Anesthesiology. 2014 May; 120(5):1262-74. PMID: 24509068; PMCID: PMC3999180.