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Jianren Mao, Ph.D., M.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01DA039925 (MAO, JIANREN) Sep 1, 2017 - Jul 31, 2020
    NIH/NIDA
    Combination Therapy with Opioid and Duloxetine for Chronic Pain Management
    Role: Principal Investigator
  2. R01DA036564 (MAO, JIANREN) Sep 15, 2013 - Dec 31, 2018
    NIH/NIDA
    Alleviating Opioid-Induced Hyperalgesia with Novel Pharmacotherapy
    Role: Principal Investigator
  3. R01DE022901 (MAO, JIANREN) Aug 1, 2012 - Jul 31, 2017
    NIH/NIDCR
    A Model and Mechanism of the Comorbid Interaction between Pain and Anxiety
    Role: Principal Investigator
  4. P20DA026002 (MAO, JIANREN) Sep 15, 2008 - Jun 30, 2013
    NIH/NIDA
    Translational Research on Prescription Drug Abuse
    Role: Principal Investigator
  5. R01DE018214 (MAO, JIANREN) Aug 4, 2008 - Jul 31, 2014
    NIH/NIDCR
    Central Mechanisms of Orofacial Pain
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. You Z, Ding W, Doheny JT, Yang J, Yang L, Lim G, Miao J, Chen L, Shen S, Mao J. Persistent Nociception Facilitates the Extinction of Morphine-Induced Conditioned Place Preference. Anesth Analg. 2018 Sep 27. PMID: 30273229.
    View in: PubMed
  2. Lin Q, Mao JH. Early prediction of acute kidney injury in children: known biomarkers but novel combination. World J Pediatr. 2018 Dec; 14(6):617-620. PMID: 30112669.
    View in: PubMed
  3. Sun EC, Mao J, Anderson TA. Treating Chronic Pain: Is Buprenorphine the (or Even an) Answer? Anesth Analg. 2018 Aug; 127(2):336-337. PMID: 30028385.
    View in: PubMed
  4. You Z, Zhang S, Shen S, Yang J, Ding W, Yang L, Lim G, Doheny JT, Tate S, Chen L, Mao J. Cognitive impairment in a rat model of neuropathic pain: role of hippocampal microtubule stability. Pain. 2018 Aug; 159(8):1518-1528. PMID: 29613911.
    View in: PubMed
  5. Albrecht DS, Ahmed SU, Kettner NW, Borra RJH, Cohen-Adad J, Deng H, Houle TT, Opalacz A, Roth SA, Melo MFV, Chen L, Mao J, Hooker JM, Loggia ML, Zhang Y. Neuroinflammation of the spinal cord and nerve roots in chronic radicular pain patients. Pain. 2018 May; 159(5):968-977. PMID: 29419657.
    View in: PubMed
  6. Jin YY, Feng BY, Mao JH. The status quo and challenges of genetic diagnosis in children with steroid-resistant nephrotic syndrome. World J Pediatr. 2018 04; 14(2):105-109. PMID: 29644498.
    View in: PubMed
  7. Shen S, Ding W, Ahmed S, Hu R, Opalacz A, Roth S, You Z, Wotjkiewicz GR, Lim G, Chen L, Mao J, Chen JW, Zhang Y. Ultrasmall Superparamagnetic Iron Oxide Imaging Identifies Tissue and Nerve Inflammation in Pain Conditions. Pain Med. 2018 Apr 01; 19(4):686-692. PMID: 29177411.
    View in: PubMed
  8. Ye Q, Mao JH, Shu Q, Shang SQ. Mycoplasma pneumoniae induces allergy by producing P1-specific immunoglobulin E. Ann Allergy Asthma Immunol. 2018 Jul; 121(1):90-97. PMID: 29555351.
    View in: PubMed
  9. Liu F, Mao JH. Calcineurin inhibitors and nephrotoxicity in children. World J Pediatr. 2018 04; 14(2):121-126. PMID: 29532435.
    View in: PubMed
  10. Ding W, You Z, Shen S, Yang J, Lim G, Doheny JT, Zhu S, Zhang Y, Chen L, Mao J. Increased HCN Channel Activity in the Gasserian Ganglion Contributes to Trigeminal Neuropathic Pain. J Pain. 2018 Jun; 19(6):626-634. PMID: 29366880.
    View in: PubMed
  11. Chen EG, Wang P, Lou H, Wang Y, Yan H, Bi L, Liu L, Li B, Snijders AM, Mao JH, Hang B. A robust gene expression-based prognostic risk score predicts overall survival of lung adenocarcinoma patients. Oncotarget. 2018 Jan 23; 9(6):6862-6871. PMID: 29467935.
    View in: PubMed
  12. Aiudi CM, Dunn RY, Burns SM, Roth SA, Opalacz A, Zhang Y, Chen L, Mao J, Ahmed SU. Loss of Efficacy to Spinal Cord Stimulator Therapy: Clinical Evidence and Possible Causes. Pain Physician. 2017 11; 20(7):E1073-E1080. PMID: 29149152.
    View in: PubMed
  13. Mi W, Wang S, You Z, Lim G, McCabe MF, Kim H, Chen L, Mao J. Nortriptyline Enhances Morphine-Conditioned Place Preference in Neuropathic Rats: Role of the Central Noradrenergic System. Anesth Analg. 2017 09; 125(3):1032-1041. PMID: 28537967.
    View in: PubMed
  14. Maher DP, Zhang Y, Ahmed S, Doshi T, Malarick C, Stabach K, Mao J, Chen L. Chronic Opioid Therapy Modifies QST Changes After Ketamine Infusion in Chronic Pain Patients. J Pain. 2017 Dec; 18(12):1468-1475. PMID: 28802882.
    View in: PubMed
  15. Maher DP, Ding W, Singh S, Opalacz A, Fishman C, Houghton M, Ahmed S, Chen L, Mao J, Zhang Y. Thermal QST Phenotypes Associated with Response to Lumbar Epidural Steroid Injections: A Pilot Study. Pain Med. 2017 Aug 01; 18(8):1455-1463. PMID: 28340251.
    View in: PubMed
  16. Shen S, Lim G, You Z, Ding W, Huang P, Ran C, Doheny J, Caravan P, Tate S, Hu K, Kim H, McCabe M, Huang B, Xie Z, Kwon D, Chen L, Mao J. Gut microbiota is critical for the induction of chemotherapy-induced pain. Nat Neurosci. 2017 Sep; 20(9):1213-1216. PMID: 28714953.
    View in: PubMed
  17. Li TX, Mao JH, Huang L, Fu HD, Chen SH, Liu AM, Liang YQ. Beneficial effects of Huaiqihuang on hyperglycemia-induced MPC5 podocyte dysfunction through the suppression of mitochondrial dysfunction and endoplasmic reticulum stress. Mol Med Rep. 2017 Aug; 16(2):1465-1471. PMID: 28627684.
    View in: PubMed
  18. Xu H, Li W, Mao JH, Pan YX. Association between red blood cell distribution width and Henoch-Schonlein purpura nephritis. Medicine (Baltimore). 2017 Jun; 96(23):e7091. PMID: 28591051.
    View in: PubMed
  19. Zhao SA, Ning BT, Mao JH. Clinical characteristics of children with hemolytic uremic syndrome in Hangzhou, China. World J Pediatr. 2017 Apr; 13(2):183-185. PMID: 28353273.
    View in: PubMed
  20. Yan H, Bi L, Wang Y, Zhang X, Hou Z, Wang Q, Snijders AM, Mao JH. Integrative analysis of multi-omics data reveals distinct impacts of DDB1-CUL4 associated factors in human lung adenocarcinomas. Sci Rep. 2017 03 23; 7(1):333. PMID: 28336923.
    View in: PubMed
  21. Ding W, You Z, Shen S, Yang J, Lim G, Doheny JT, Chen L, Zhu S, Mao J. An Improved Rodent Model of Trigeminal Neuropathic Pain by Unilateral Chronic Constriction Injury of Distal Infraorbital Nerve. J Pain. 2017 Aug; 18(8):899-907. PMID: 28238950.
    View in: PubMed
  22. Mao J. Challenges of managing chronic pain. BMJ. 2017 Feb 17; 356:j741. PMID: 28213344.
    View in: PubMed
  23. Wang Y, Zhang P, Wang Y, Zhan P, Liu C, Mao JH, Wei G. Distinct Interactions of EBP1 Isoforms with FBXW7 Elicits Different Functions in Cancer. Cancer Res. 2017 04 15; 77(8):1983-1996. PMID: 28209614.
    View in: PubMed
  24. Maher DP, Chen L, Mao J. Intravenous Ketamine Infusions for Neuropathic Pain Management: A Promising Therapy in Need of Optimization. Anesth Analg. 2017 02; 124(2):661-674. PMID: 28067704.
    View in: PubMed
  25. Mao JH, Huang QH, Liu P, Luo C, Xi XD. [Role and Mechanism of the Interaction of BCR-ABL with E3 Ligase c-CBL in Targeting Therapy of Chronic Myelogenous Leukemia]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017 Feb; 25(1):42-49. PMID: 28245373.
    View in: PubMed
  26. Schaller SJ, Alam SM, Mao J, Zhao Y, Blobner M, Greenblatt DJ, Martyn JA. Pharmacokinetics cannot explain the increased effective dose requirement for morphine and midazolam in rats during their extended administration alone or in combination. J Pharm Pharmacol. 2017 Jan; 69(1):82-88. PMID: 27891611.
    View in: PubMed
  27. Jin YY, He MZ, Wu ZY, Huang K, Shen Y, Liang L, Mao JH. Dysregulation of calcium channels decreases parasecretion in pancreatic ß-cells in rats born small for gestational age. Growth Factors. 2016 12; 34(5-6):159-165. PMID: 27681688.
    View in: PubMed
  28. Rusanescu G, Mao J. Peripheral nerve injury induces adult brain neurogenesis and remodelling. J Cell Mol Med. 2017 02; 21(2):299-314. PMID: 27665307.
    View in: PubMed
  29. Chen X, Spaeth RB, Freeman SG, Scarborough DM, Hashmi JA, Wey HY, Egorova N, Vangel M, Mao J, Wasan AD, Edwards RR, Gollub RL, Kong J. The Modulation Effect of Longitudinal Acupuncture on Resting State Functional Connectivity in Knee Osteoarthritis Patients. Mol Pain. 2015 01; 11. PMID: 27655921.
    View in: PubMed
  30. Ding W, You Z, Shen S, Chen L, Zhu S, Mao J. Inhibition of HCN channel activity in the thalamus attenuates chronic pain in rats. Neurosci Lett. 2016 Sep 19; 631:97-103. PMID: 27542339.
    View in: PubMed
  31. Ye Q, Fu JF, Mao JH, Shang SQ. Haze is a risk factor contributing to the rapid spread of respiratory syncytial virus in children. Environ Sci Pollut Res Int. 2016 Oct; 23(20):20178-20185. PMID: 27439752.
    View in: PubMed
  32. Ye Q, Fu JF, Mao JH, Shen HQ, Chen XJ, Shao WX, Shang SQ, Wu YF. Haze is an important medium for the spread of rotavirus. Environ Pollut. 2016 Sep; 216:324-331. PMID: 27289527.
    View in: PubMed
  33. Xu H, Pan YX, Zhang J, Liu Y, Mao JH, Li W. Lack of Association between Interleukin-8 Gene +781 C/T Polymorphism and Henoch-Schönlein Purpura in Childhood. Iran J Allergy Asthma Immunol. 2016 Jun; 15(3):237-43. PMID: 27424139.
    View in: PubMed
  34. Yao Y, Tan YH, Light AR, Mao J, Yu AC, Fu KY. Alendronate Attenuates Spinal Microglial Activation and Neuropathic Pain. J Pain. 2016 08; 17(8):889-903. PMID: 27063783.
    View in: PubMed
  35. Hung MS, Chen IC, You L, Jablons DM, Li YC, Mao JH, Xu Z, Lung JH, Yang CT, Liu ST. Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells. J Cell Mol Med. 2016 07; 20(7):1295-306. PMID: 26969027; PMCID: PMC4929302.
    View in: PubMed, PubMed Central
  36. Wang JJ, Mao JH. The etiology of congenital nephrotic syndrome: current status and challenges. World J Pediatr. 2016 May; 12(2):149-58. PMID: 26961288.
    View in: PubMed
  37. Zheng XY, Xu J, Li W, Li SS, Shi CP, Zhao ZY, Mao JH, Chen X. Frosted Branch Angiitis in Pediatric Dyskeratosis Congenita: A Case Report. Medicine (Baltimore). 2016 Mar; 95(12):e3106. PMID: 27015183; PMCID: PMC4998378.
    View in: PubMed, PubMed Central
  38. Ye Q, Shao WX, Shang SQ, Shen HQ, Chen XJ, Tang YM, Yu YL, Mao JH. Clinical Value of Assessing Cytokine Levels for the Differential Diagnosis of Bacterial Meningitis in a Pediatric Population. Medicine (Baltimore). 2016 Mar; 95(13):e3222. PMID: 27043692; PMCID: PMC4998553.
    View in: PubMed, PubMed Central
  39. Zhang S, You Z, Wang S, Yang J, Yang L, Sun Y, Mi W, Yang L, McCabe MF, Shen S, Chen L, Mao J. Neuropeptide S modulates the amygdaloidal HCN activities (Ih) in rats: Implication in chronic pain. Neuropharmacology. 2016 06; 105:420-433. PMID: 26855147.
    View in: PubMed
  40. Lee CT, Vo TT, Cohen AS, Ahmed S, Zhang Y, Mao J, Chen L. Profiles of Urine Drug Test in Clinical Pain Patients vs Pain Research Study Subjects. Pain Med. 2016 Apr; 17(4):636-43. PMID: 26398237; PMCID: PMC4805511 [Available on 04/01/17].
    View in: PubMed, PubMed Central
  41. Zhai X, Sun C, Rong P, Li S, McCabe MF, Wang X, Mao J, Wang S. A Correlative Relationship Between Chronic Pain and Insulin Resistance in Zucker Fatty Rats: Role of Downregulation of Insulin Receptors. J Pain. 2016 Apr; 17(4):404-13. PMID: 26705975.
    View in: PubMed
  42. Mao J. Clinical Diagnosis of Opioid-Induced Hyperalgesia. Reg Anesth Pain Med. 2015 Nov-Dec; 40(6):663-4. PMID: 26488079.
    View in: PubMed
  43. Chen X, Spaeth RB, Freeman SG, Scarborough DM, Hashmi JA, Wey HY, Egorova N, Vangel M, Mao J, Wasan AD, Edwards RR, Gollub RL, Kong J. The modulation effect of longitudinal acupuncture on resting state functional connectivity in knee osteoarthritis patients. Mol Pain. 2015 Oct 29; 11:67. PMID: 26511911; PMCID: PMC4625557.
    View in: PubMed, PubMed Central
  44. Xu B, Chen M, Yao M, Ji X, Mao Z, Tang W, Qiao S, Schick SF, Mao JH, Hang B, Xia Y. Metabolomics reveals metabolic changes in male reproductive cells exposed to thirdhand smoke. Sci Rep. 2015 Oct 22; 5:15512. PMID: 26489853; PMCID: PMC4614949.
    View in: PubMed, PubMed Central
  45. Wen M, Kwon Y, Wang Y, Mao JH, Wei G. Elevated expression of UBE2T exhibits oncogenic properties in human prostate cancer. Oncotarget. 2015 Sep 22; 6(28):25226-39. PMID: 26308072; PMCID: PMC4694827.
    View in: PubMed, PubMed Central
  46. Rusanescu G, Mao J. Immature spinal cord neurons are dynamic regulators of adult nociceptive sensitivity. J Cell Mol Med. 2015 Oct; 19(10):2352-64. PMID: 26223362; PMCID: PMC4594677.
    View in: PubMed, PubMed Central
  47. Yang YL, Ni J, Hsu PC, Mao JH, Hsieh D, Xu A, Chan G, Au A, Xu Z, Jablons DM, You L. Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma. J Cell Mol Med. 2015 Oct; 19(10):2385-96. PMID: 26218750; PMCID: PMC4594680.
    View in: PubMed, PubMed Central
  48. Bicket MC, Mao J. Chronic Pain in Older Adults. Anesthesiol Clin. 2015 Sep; 33(3):577-90. PMID: 26315639.
    View in: PubMed
  49. Ahmed SU, Zhang Y, Chen L, Cohen A, St Hillary K, Vo T, Houghton M, Mao J. Effect of 1.5% Topical Diclofenac on Clinical Neuropathic Pain. Anesthesiology. 2015 Jul; 123(1):191-8. PMID: 25955980.
    View in: PubMed
  50. Jamison RN, Mao J. Opioid Analgesics. Mayo Clin Proc. 2015 Jul; 90(7):957-68. PMID: 26141334.
    View in: PubMed
  51. Ahmed SU, Zhang Y, Chen L, St Hillary K, Cohen A, Vo T, Houghton M, Mao J. Effects of Spinal Cord Stimulation on Pain Thresholds and Sensory Perceptions in Chronic Pain Patients. Neuromodulation. 2015 Jul; 18(5):355-60. PMID: 26033205.
    View in: PubMed
  52. Tsui JI, Lira MC, Cheng DM, Winter MR, Alford DP, Liebschutz JM, Mao J, Edwards RR, Samet JH. Hepatitis C virus infection and pain sensitivity in patients on methadone or buprenorphine maintenance therapy for opioid use disorders. Drug Alcohol Depend. 2015 Aug 01; 153:286-92. PMID: 26048638; PMCID: PMC4509826.
    View in: PubMed, PubMed Central
  53. Ye Q, Shang SQ, Liu AM, Zhang T, Shen HQ, Chen XJ, Mao JH. 24h Urinary Protein Levels and Urine Protein/Creatinine Ratios Could Probably Forecast the Pathological Classification of HSPN. PLoS One. 2015; 10(5):e0127767. PMID: 25996387; PMCID: PMC4440756.
    View in: PubMed, PubMed Central
  54. Blasi F, Herisson F, Wang S, Mao J, Ayata C. Late-onset thermal hypersensitivity after focal ischemic thalamic infarcts as a model for central post-stroke pain in rats. J Cereb Blood Flow Metab. 2015 Jul; 35(7):1100-3. PMID: 25899295; PMCID: PMC4640279.
    View in: PubMed, PubMed Central
  55. You B, Yang YL, Xu Z, Dai Y, Liu S, Mao JH, Tetsu O, Li H, Jablons DM, You L. Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells. Oncotarget. 2015 Feb 28; 6(6):4357-68. PMID: 25738359; PMCID: PMC4414195.
    View in: PubMed, PubMed Central
  56. Chen JY, Mao JH. Henoch-Schönlein purpura nephritis in children: incidence, pathogenesis and management. World J Pediatr. 2015 Feb; 11(1):29-34. PMID: 25557596.
    View in: PubMed
  57. Pan YX, Ye Q, Shao WX, Shang SQ, Mao JH, Zhang T, Shen HQ, Zhao N. Relationship between immune parameters and organ involvement in children with Henoch-Schonlein purpura. PLoS One. 2014; 9(12):e115261. PMID: 25514176; PMCID: PMC4267823.
    View in: PubMed, PubMed Central
  58. Ueda M, Iwasaki H, Wang S, Murata E, Poon KY, Mao J, Martyn JA. Cannabinoid receptor type 1 antagonist, AM251, attenuates mechanical allodynia and thermal hyperalgesia after burn injury. Anesthesiology. 2014 Dec; 121(6):1311-9. PMID: 25188001; PMCID: PMC4237656.
    View in: PubMed, PubMed Central
  59. Zhang Y, Ahmed S, Vo T, St Hilaire K, Houghton M, Cohen AS, Mao J, Chen L. Increased pain sensitivity in chronic pain subjects on opioid therapy: a cross-sectional study using quantitative sensory testing. Pain Med. 2015 May; 16(5):911-22. PMID: 25376890.
    View in: PubMed
  60. Chen L, Sein M, Vo T, Amhmed S, Zhang Y, Hilaire KS, Houghton M, Mao J. Clinical interpretation of opioid tolerance versus opioid-induced hyperalgesia. J Opioid Manag. 2014 Nov-Dec; 10(6):383-93. PMID: 25531956.
    View in: PubMed
  61. Rusanescu G, Mao J. Notch3 is necessary for neuronal differentiation and maturation in the adult spinal cord. J Cell Mol Med. 2014 Oct; 18(10):2103-16. PMID: 25164209; PMCID: PMC4244024.
    View in: PubMed, PubMed Central
  62. Yang L, Xin X, Zhang J, Zhang L, Dong Y, Zhang Y, Mao J, Xie Z. Inflammatory pain may induce cognitive impairment through an interlukin-6-dependent and postsynaptic density-95-associated mechanism. Anesth Analg. 2014 Aug; 119(2):471-80. PMID: 24878682; PMCID: PMC4107025.
    View in: PubMed, PubMed Central
  63. Lim G, Kim H, McCabe MF, Chou CW, Wang S, Chen LL, Marota JJ, Blood A, Breiter HC, Mao J. A leptin-mediated central mechanism in analgesia-enhanced opioid reward in rats. J Neurosci. 2014 Jul 16; 34(29):9779-88. PMID: 25031415; PMCID: PMC4099551.
    View in: PubMed, PubMed Central
  64. Fell GL, Robinson KC, Mao J, Woolf CJ, Fisher DE. Skin ß-endorphin mediates addiction to UV light. Cell. 2014 Jun 19; 157(7):1527-34. PMID: 24949966; PMCID: PMC4117380.
    View in: PubMed, PubMed Central
  65. Zhang S, Jin X, You Z, Wang S, Lim G, Yang J, McCabe M, Li N, Marota J, Chen L, Mao J. Persistent nociception induces anxiety-like behavior in rodents: role of endogenous neuropeptide S. Pain. 2014 Aug; 155(8):1504-15. PMID: 24793908; PMCID: PMC4104217.
    View in: PubMed, PubMed Central
  66. Chen KY, Chen L, Mao J. Buprenorphine-naloxone therapy in pain management. Anesthesiology. 2014 May; 120(5):1262-74. PMID: 24509068; PMCID: PMC3999180.
    View in: PubMed, PubMed Central
  67. Song L, Wang S, Zuo Y, Chen L, Martyn JA, Mao J. Midazolam exacerbates morphine tolerance and morphine-induced hyperactive behaviors in young rats with burn injury. Brain Res. 2014 May 20; 1564:52-61. PMID: 24713351; PMCID: PMC4042400.
    View in: PubMed, PubMed Central
  68. Cohen SP, Mao J. Neuropathic pain: mechanisms and their clinical implications. BMJ. 2014 Feb 05; 348:f7656. PMID: 24500412.
    View in: PubMed
  69. Wang Y, Wen M, Kwon Y, Xu Y, Liu Y, Zhang P, He X, Wang Q, Huang Y, Jen KY, LaBarge MA, You L, Kogan SC, Gray JW, Mao JH, Wei G. CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression. Cancer Res. 2014 Jan 15; 74(2):520-31. PMID: 24305877; PMCID: PMC3934357.
    View in: PubMed, PubMed Central
  70. Zhang X, Xin X, Dong Y, Zhang Y, Yu B, Mao J, Xie Z. Surgical incision-induced nociception causes cognitive impairment and reduction in synaptic NMDA receptor 2B in mice. J Neurosci. 2013 Nov 06; 33(45):17737-48. PMID: 24198365; PMCID: PMC3818549.
    View in: PubMed, PubMed Central
  71. Ma Y, Wang S, Tian Y, Chen L, Li G, Mao J. Disruption of persistent nociceptive behavior in rats with learning impairment. PLoS One. 2013; 8(9):e74533. PMID: 24040273; PMCID: PMC3770575.
    View in: PubMed, PubMed Central
  72. Chen L, Mao J. Update on neuropathic pain treatment: ion channel blockers and gabapentinoids. Curr Pain Headache Rep. 2013 Sep; 17(9):359. PMID: 23888370.
    View in: PubMed
  73. Li N, Lim G, Chen L, McCabe MF, Kim H, Zhang S, Mao J. Spinal expression of Hippo signaling components YAP and TAZ following peripheral nerve injury in rats. Brain Res. 2013 Oct 16; 1535:137-47. PMID: 23998984; PMCID: PMC3822441.
    View in: PubMed, PubMed Central
  74. Qian GL, Huang L, Liu AM, Gu WZ, Fu HD, Mao JH. [Acute kidney injury induced by favism in children: a case report]. Zhonghua Xue Ye Xue Za Zhi. 2013 Aug; 34(8):708. PMID: 23978025.
    View in: PubMed
  75. Feng CY, Xia YH, Wang WJ, Xia J, Fu HD, Wang X, Shen HJ, Qian GL, Liu AM, Mao JH. Persistent asymptomatic isolated hematuria in children: clinical and histopathological features and prognosis. World J Pediatr. 2013 May; 9(2):163-8. PMID: 23677832.
    View in: PubMed
  76. Lu J, Wen M, Huang Y, He X, Wang Y, Wu Q, Li Z, Castellanos-Martin A, Abad M, Cruz-Hernandez JJ, Rodriguez CA, Pérez-Losada J, Mao JH, Wei G. C2ORF40 suppresses breast cancer cell proliferation and invasion through modulating expression of M phase cell cycle genes. Epigenetics. 2013 Jun; 8(6):571-83. PMID: 23770814; PMCID: PMC3857337.
    View in: PubMed, PubMed Central
  77. Chen L, Vo T, Seefeld L, Malarick C, Houghton M, Ahmed S, Zhang Y, Cohen A, Retamozo C, St Hilaire K, Zhang V, Mao J. Lack of correlation between opioid dose adjustment and pain score change in a group of chronic pain patients. J Pain. 2013 Apr; 14(4):384-92. PMID: 23452826.
    View in: PubMed
  78. Bruehl S, Apkarian AV, Ballantyne JC, Berger A, Borsook D, Chen WG, Farrar JT, Haythornthwaite JA, Horn SD, Iadarola MJ, Inturrisi CE, Lao L, Mackey S, Mao J, Sawczuk A, Uhl GR, Witter J, Woolf CJ, Zubieta JK, Lin Y. Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges. J Pain. 2013 Feb; 14(2):103-13. PMID: 23374939.
    View in: PubMed
  79. Cohen SP, Mao J, Vu TN, Strassels SA, Gupta A, Erdek MA, Christo PJ, Kurihara C, Griffith SR, Buckenmaier CC, Chen L. Does pain score in response to a standardized subcutaneous local anesthetic injection predict epidural steroid injection outcomes in patients with lumbosacral radiculopathy? A prospective correlational study. Pain Med. 2013 Mar; 14(3):327-35. PMID: 23294538.
    View in: PubMed
  80. Kang HC, Wakabayashi Y, Jen KY, Mao JH, Zoumpourlis V, Del Rosario R, Balmain A. Ptch1 overexpression drives skin carcinogenesis and developmental defects in K14Ptch(FVB) mice. J Invest Dermatol. 2013 May; 133(5):1311-20. PMID: 23223138; PMCID: PMC3610826.
    View in: PubMed, PubMed Central
  81. Shen J, Xu S, Shi LP, Mao JH, Ye JJ. [Management of fungal pyelonephritis with percutaneous pyelostomy in infants]. Zhonghua Er Ke Za Zhi. 2012 Dec; 50(12):935-8. PMID: 23324153.
    View in: PubMed
  82. Liu Y, Ren S, Castellanos-Martin A, Perez-Losada J, Kwon YW, Huang Y, Wang Z, Abad M, Cruz-Hernandez JJ, Rodriguez CA, Sun Y, Mao JH. Multiple novel alternative splicing forms of FBXW7a have a translational modulatory function and show specific alteration in human cancer. PLoS One. 2012; 7(11):e49453. PMID: 23166673; PMCID: PMC3498124.
    View in: PubMed, PubMed Central
  83. Wang S, Song L, Tan Y, Ma Y, Tian Y, Jin X, Lim G, Zhang S, Chen L, Mao J. A functional relationship between trigeminal astroglial activation and NR1 expression in a rat model of temporomandibular joint inflammation. Pain Med. 2012 Dec; 13(12):1590-600. PMID: 23110394; PMCID: PMC3527674.
    View in: PubMed, PubMed Central
  84. Snijders AM, Marchetti F, Bhatnagar S, Duru N, Han J, Hu Z, Mao JH, Gray JW, Wyrobek AJ. Genetic differences in transcript responses to low-dose ionizing radiation identify tissue functions associated with breast cancer susceptibility. PLoS One. 2012; 7(10):e45394. PMID: 23077491; PMCID: PMC3471924.
    View in: PubMed, PubMed Central
  85. Wang S, Tian Y, Song L, Lim G, Tan Y, You Z, Chen L, Mao J. Exacerbated mechanical hyperalgesia in rats with genetically predisposed depressive behavior: role of melatonin and NMDA receptors. Pain. 2012 Dec; 153(12):2448-57. PMID: 23046768; PMCID: PMC3494817.
    View in: PubMed, PubMed Central
  86. Mao J. Current challenges in translational pain research. Trends Pharmacol Sci. 2012 Nov; 33(11):568-73. PMID: 22959652; PMCID: PMC3482290.
    View in: PubMed, PubMed Central
  87. Mulvihill MS, Kwon YW, Lee S, Fang LT, Choi H, Ray R, Kang HC, Mao JH, Jablons D, Kim IJ. Gremlin is overexpressed in lung adenocarcinoma and increases cell growth and proliferation in normal lung cells. PLoS One. 2012; 7(8):e42264. PMID: 22870311; PMCID: PMC3411619.
    View in: PubMed, PubMed Central
  88. Okumura K, Sato M, Saito M, Miura I, Wakana S, Mao JH, Miyasaka Y, Kominami R, Wakabayashi Y. Independent genetic control of early and late stages of chemically induced skin tumors in a cross of a Japanese wild-derived inbred mouse strain, MSM/Ms. Carcinogenesis. 2012 Nov; 33(11):2260-8. PMID: 22843548.
    View in: PubMed
  89. Li M, Chen H, Tang J, Hao J, Chen J, Mao J. Characterization of nociceptive responses to bee venom-induced inflammation in neonatal rats. Brain Res. 2012 Sep 07; 1472:54-62. PMID: 22800806.
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  90. Kim H, Chen L, Lim G, Sung B, Wang S, McCabe MF, Rusanescu G, Yang L, Tian Y, Mao J. Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression. J Clin Invest. 2012 Aug; 122(8):2940-54. PMID: 22751107; PMCID: PMC3408737.
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  91. Zhang S, Wang Y, Mao JH, Hsieh D, Kim IJ, Hu LM, Xu Z, Long H, Jablons DM, You L. Inhibition of CK2a down-regulates Hedgehog/Gli signaling leading to a reduction of a stem-like side population in human lung cancer cells. PLoS One. 2012; 7(6):e38996. PMID: 22768056; PMCID: PMC3387212.
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  92. Kwon YW, Kim IJ, Wu D, Lu J, Stock WA, Liu Y, Huang Y, Kang HC, DelRosario R, Jen KY, Perez-Losada J, Wei G, Balmain A, Mao JH. Pten regulates Aurora-A and cooperates with Fbxw7 in modulating radiation-induced tumor development. Mol Cancer Res. 2012 Jun; 10(6):834-44. PMID: 22513362; PMCID: PMC3388112.
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  93. Ren S, Xu C, Cui Z, Yu Y, Xu W, Wang F, Lu J, Wei M, Lu X, Gao X, Liang Y, Mao JH, Sun Y. Oncogenic CUL4A determines the response to thalidomide treatment in prostate cancer. J Mol Med (Berl). 2012 Oct; 90(10):1121-32. PMID: 22422151; PMCID: PMC3650856.
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  94. Perez-Losada J, Wu D, DelRosario R, Balmain A, Mao JH. Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility. PLoS One. 2012; 7(2):e31301. PMID: 22348067; PMCID: PMC3278431.
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  95. Brenner GJ, Kueppenbender K, Mao J, Spike J. Ethical challenges and interventional pain medicine. Curr Pain Headache Rep. 2012 Feb; 16(1):1-8. PMID: 22160519.
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  96. Vorobeychik Y, Gordin V, Mao J, Chen L. Combination therapy for neuropathic pain: a review of current evidence. CNS Drugs. 2011 Dec 01; 25(12):1023-34. PMID: 22133325.
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  97. Yao SH, Mao JH, Xia YH, Wang DY, Chen YF, Fang CQ, Liu AM, Du LZ. [Clinical application of tacrolimus with low-dose prednisone in 21 children with steroid-resistant nephrotic syndrome]. Zhonghua Er Ke Za Zhi. 2011 Nov; 49(11):825-8. PMID: 22336304.
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  98. Wang YV, Leblanc M, Fox N, Mao JH, Tinkum KL, Krummel K, Engle D, Piwnica-Worms D, Piwnica-Worms H, Balmain A, Kaushansky K, Wahl GM. Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity. Genes Dev. 2011 Jul 01; 25(13):1426-38. PMID: 21724834; PMCID: PMC3134085.
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  99. Chen L, Houghton M, Seefeld L, Malarick C, Mao J. Opioid therapy for chronic pain: physicians' attitude and current practice patterns. J Opioid Manag. 2011 Jul-Aug; 7(4):267-76. PMID: 21957826.
    View in: PubMed
  100. Chen SJ, Zhou GB, Zhang XW, Mao JH, de Thé H, Chen Z. From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia. Blood. 2011 Jun 16; 117(24):6425-37. PMID: 21422471; PMCID: PMC3123014.
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  101. Tian Y, Wang S, Ma Y, Lim G, Kim H, Mao J. Leptin enhances NMDA-induced spinal excitation in rats: A functional link between adipocytokine and neuropathic pain. Pain. 2011 Jun; 152(6):1263-71. PMID: 21376468; PMCID: PMC3098907.
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  102. Hung MS, Mao JH, Xu Z, Yang CT, Yu JS, Harvard C, Lin YC, Bravo DT, Jablons DM, You L. Cul4A is an oncogene in malignant pleural mesothelioma. J Cell Mol Med. 2011 Feb; 15(2):350-8. PMID: 19929949; PMCID: PMC3355981.
    View in: PubMed, PubMed Central
  103. Chou CW, Wong GT, Lim G, McCabe MF, Wang S, Irwin MG, Mao J. Peripheral nerve injury alters the expression of NF-?B in the rat's hippocampus. Brain Res. 2011 Mar 10; 1378:66-71. PMID: 21223950; PMCID: PMC3042522.
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  104. Ci SP, Gao Y, Zhang XL, Mao JH, Zhao NZ, Ni JQ, Shen X, Ding M, Xu XX. [Twenty years follow-up: the correlation between sleep apnea syndrome and cerebrovascular disease]. Zhonghua Jie He He Hu Xi Za Zhi. 2011 Jan; 34(1):13-6. PMID: 21429412.
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  105. Wang S, Zhang L, Ma Y, Chen L, Tian Y, Mao J, Martyn JJ. Nociceptive behavior following hindpaw burn injury in young rats: response to systemic morphine. Pain Med. 2011 Jan; 12(1):87-98. PMID: 21143761; PMCID: PMC3059240.
    View in: PubMed, PubMed Central
  106. Mao JH, Sun XY, Liu JX, Zhang QY, Liu P, Huang QH, Li KK, Chen Q, Chen Z, Chen SJ. As4S4 targets RING-type E3 ligase c-CBL to induce degradation of BCR-ABL in chronic myelogenous leukemia. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21683-8. PMID: 21118980; PMCID: PMC3003020.
    View in: PubMed, PubMed Central
  107. Mao J, Gold MS, Backonja MM. Combination drug therapy for chronic pain: a call for more clinical studies. J Pain. 2011 Feb; 12(2):157-66. PMID: 20851058; PMCID: PMC3006488.
    View in: PubMed, PubMed Central
  108. Hung MS, Lin YC, Mao JH, Kim IJ, Xu Z, Yang CT, Jablons DM, You L. Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer. PLoS One. 2010 Jul 02; 5(7):e11418. PMID: 20625391; PMCID: PMC2896393.
    View in: PubMed, PubMed Central
  109. Kim H, Oh S, Sung B, Tian Y, Yang L, Wang S, Mao J. Anti-morphine antibody contributes to the development of morphine tolerance in rats. Neurosci Lett. 2010 Aug 23; 480(3):196-200. PMID: 20561567; PMCID: PMC2907472.
    View in: PubMed, PubMed Central
  110. Chou CW, Wong GT, Lim G, Wang S, Irwin MG, Mao J. Spatiotemporal pattern of concurrent spinal and supraspinal NF-?B expression after peripheral nerve injury. J Pain. 2011 Jan; 12(1):13-21. PMID: 20537956; PMCID: PMC2978259.
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  111. Li K, Fu KY, Light AR, Mao J. Systemic minocycline differentially influences changes in spinal microglial markers following formalin-induced nociception. J Neuroimmunol. 2010 Apr 15; 221(1-2):25-31. PMID: 20202692; PMCID: PMC2874948.
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  112. Chen L, Houghton M, Seefeld L, Malarick C, Mao J. A survey of selected physician views on acupuncture in pain management. Pain Med. 2010 Apr; 11(4):530-4. PMID: 20202145.
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  113. Mao J. N-type calcium channel blocker for pain treatment. Pain Med. 2010 Feb; 11(2):153. PMID: 20447299.
    View in: PubMed
  114. Carinci AJ, Mao J. Pain and opioid addiction: what is the connection? Curr Pain Headache Rep. 2010 Feb; 14(1):17-21. PMID: 20425210.
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  115. Kim H, Sung B, Mao J. Animal models of acute surgical pain. Methods Mol Biol. 2010; 617:31-9. PMID: 20336411.
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  116. Shen HJ, Dai YW, Mao JH, Liu AM. Concurrence of Bartter syndrome and minimal change nephrotic syndrome. Chin Med J (Engl). 2009 Aug 05; 122(15):1834-8. PMID: 19781336.
    View in: PubMed
  117. Mao J. Translational pain research: achievements and challenges. J Pain. 2009 Oct; 10(10):1001-11. PMID: 19628433; PMCID: PMC2757533.
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  118. Wang S, Zhang L, Lim G, Sung B, Tian Y, Chou CW, Hernstadt H, Rusanescu G, Ma Y, Mao J. A combined effect of dextromethorphan and melatonin on neuropathic pain behavior in rats. Brain Res. 2009 Sep 08; 1288:42-9. PMID: 19595681; PMCID: PMC2744035.
    View in: PubMed, PubMed Central
  119. Hernstadt H, Wang S, Lim G, Mao J. Spinal translocator protein (TSPO) modulates pain behavior in rats with CFA-induced monoarthritis. Brain Res. 2009 Aug 25; 1286:42-52. PMID: 19555675; PMCID: PMC2749299.
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  120. Chen L, Malarick C, Seefeld L, Wang S, Houghton M, Mao J. Altered quantitative sensory testing outcome in subjects with opioid therapy. Pain. 2009 May; 143(1-2):65-70. PMID: 19237249; PMCID: PMC2680088.
    View in: PubMed, PubMed Central
  121. Zhang QY, Mao JH, Liu P, Huang QH, Lu J, Xie YY, Weng L, Zhang Y, Chen Q, Chen SJ, Chen Z. A systems biology understanding of the synergistic effects of arsenic sulfide and Imatinib in BCR/ABL-associated leukemia. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):3378-83. PMID: 19208803; PMCID: PMC2651272.
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  122. Lim G, Wang S, Zhang Y, Tian Y, Mao J. Spinal leptin contributes to the pathogenesis of neuropathic pain in rodents. J Clin Invest. 2009 Feb; 119(2):295-304. PMID: 19139561; PMCID: PMC2631299.
    View in: PubMed, PubMed Central
  123. Wang S, Lim G, Mao J, Sung B, Mao J. Regulation of the trigeminal NR1 subunit expression induced by inflammation of the temporomandibular joint region in rats. Pain. 2009 Jan; 141(1-2):97-103. PMID: 19058915; PMCID: PMC3491650.
    View in: PubMed, PubMed Central
  124. Fu KY, Tan YH, Sung B, Mao J. Peripheral formalin injection induces unique spinal cord microglial phenotypic changes. Neurosci Lett. 2009 Jan 16; 449(3):234-9. PMID: 19015000; PMCID: PMC4082795.
    View in: PubMed, PubMed Central
  125. Yang L, Wang S, Lim G, Sung B, Zeng Q, Mao J. Inhibition of the ubiquitin-proteasome activity prevents glutamate transporter degradation and morphine tolerance. Pain. 2008 Dec; 140(3):472-8. PMID: 18986766; PMCID: PMC3454498.
    View in: PubMed, PubMed Central
  126. Cohen SP, Wang S, Chen L, Kurihara C, McKnight G, Marcuson M, Mao J. An intravenous ketamine test as a predictive response tool in opioid-exposed patients with persistent pain. J Pain Symptom Manage. 2009 Apr; 37(4):698-708. PMID: 18789637.
    View in: PubMed
  127. Vorobeychik Y, Chen L, Bush MC, Mao J. Improved opioid analgesic effect following opioid dose reduction. Pain Med. 2008 Sep; 9(6):724-7. PMID: 18816332.
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  128. Yang L, Wang S, Sung B, Lim G, Mao J. Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation. J Biol Chem. 2008 Aug 01; 283(31):21703-13. PMID: 18539596; PMCID: PMC2490772.
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  129. Cohen SP, Christo PJ, Wang S, Chen L, Stojanovic MP, Shields CH, Brummett C, Mao J. The effect of opioid dose and treatment duration on the perception of a painful standardized clinical stimulus. Reg Anesth Pain Med. 2008 May-Jun; 33(3):199-206. PMID: 18433669.
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  130. Wang L, Zhou GB, Liu P, Song JH, Liang Y, Yan XJ, Xu F, Wang BS, Mao JH, Shen ZX, Chen SJ, Chen Z. Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4826-31. PMID: 18344322; PMCID: PMC2290784.
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  131. Zeng Q, Wang S, Lim G, Yang L, Mao J, Sung B, Chang Y, Lim JA, Guo G, Mao J. Exacerbated mechanical allodynia in rats with depression-like behavior. Brain Res. 2008 Mar 20; 1200:27-38. PMID: 18289511; PMCID: PMC2386964.
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  132. Gu X, Yang L, Wang S, Sung B, Lim G, Mao J, Zeng Q, Yang C, Mao J. A rat model of radicular pain induced by chronic compression of lumbar dorsal root ganglion with SURGIFLO. Anesthesiology. 2008 Jan; 108(1):113-21. PMID: 18156889.
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  133. Singla A, Stojanovic MP, Chen L, Mao J. A differential diagnosis of hyperalgesia, toxicity, and withdrawal from intrathecal morphine infusion. Anesth Analg. 2007 Dec; 105(6):1816-9, table of contents. PMID: 18042887.
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  134. Gu X, Wang S, Yang L, Sung B, Lim G, Mao J, Zeng Q, Chang Y, Mao J. Time-dependent effect of epidural steroid on pain behavior induced by chronic compression of dorsal root ganglion in rats. Brain Res. 2007 Oct 12; 1174:39-46. PMID: 17869229; PMCID: PMC3468942.
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  135. Xue X, Zhu YF, Mao JP. [Effect of RNA interference for Lon gene silencing on growth and apoptosis of human breast cancer MCF7 cells]. Nan Fang Yi Ke Da Xue Xue Bao. 2007 Jun; 27(6):870-4. PMID: 17584658.
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  136. Chang G, Chen L, Mao J. Opioid tolerance and hyperalgesia. Med Clin North Am. 2007 Mar; 91(2):199-211. PMID: 17321281.
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  137. Sung B, Wang S, Zhou B, Lim G, Yang L, Zeng Q, Lim JA, Wang JD, Kang JX, Mao J. Altered spinal arachidonic acid turnover after peripheral nerve injury regulates regional glutamate concentration and neuropathic pain behaviors in rats. Pain. 2007 Sep; 131(1-2):121-31. PMID: 17267128; PMCID: PMC2478515.
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  138. Wang S, Lim G, Mao J, Sung B, Yang L, Mao J. Central glucocorticoid receptors regulate the upregulation of spinal cannabinoid-1 receptors after peripheral nerve injury in rats. Pain. 2007 Sep; 131(1-2):96-105. PMID: 17258396.
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  139. Lim J, Lim G, Sung B, Wang S, Mao J. Intrathecal midazolam regulates spinal AMPA receptor expression and function after nerve injury in rats. Brain Res. 2006 Dec 06; 1123(1):80-8. PMID: 17049496; PMCID: PMC1974870.
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  140. Cohen SP, Verdolin MH, Chang AS, Kurihara C, Morlando BJ, Mao J. The intravenous ketamine test predicts subsequent response to an oral dextromethorphan treatment regimen in fibromyalgia patients. J Pain. 2006 Jun; 7(6):391-8. PMID: 16750795.
    View in: PubMed
  141. Mao J. Opioid-induced abnormal pain sensitivity. Curr Pain Headache Rep. 2006 Feb; 10(1):67-70. PMID: 16499832.
    View in: PubMed
  142. Wang S, Lim G, Yang L, Sung B, Mao J. Downregulation of spinal glutamate transporter EAAC1 following nerve injury is regulated by central glucocorticoid receptors in rats. Pain. 2006 Jan; 120(1-2):78-85. PMID: 16360273.
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  143. Lim G, Wang S, Lim JA, Mao J. Activity of adenylyl cyclase and protein kinase A contributes to morphine-induced spinal apoptosis. Neurosci Lett. 2005 Dec 02; 389(2):104-8. PMID: 16102899.
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  144. Lim G, Wang S, Zeng Q, Sung B, Yang L, Mao J. Expression of spinal NMDA receptor and PKCgamma after chronic morphine is regulated by spinal glucocorticoid receptor. J Neurosci. 2005 Nov 30; 25(48):11145-54. PMID: 16319314.
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  145. Lim G, Wang S, Mao J. Central glucocorticoid receptors modulate the expression of spinal cannabinoid receptors induced by chronic morphine exposure. Brain Res. 2005 Oct 12; 1059(1):20-7. PMID: 16150424.
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  146. Wang S, Lim G, Yang L, Zeng Q, Sung B, Jeevendra Martyn JA, Mao J. A rat model of unilateral hindpaw burn injury: slowly developing rightwards shift of the morphine dose-response curve. Pain. 2005 Jul; 116(1-2):87-95. PMID: 15936884.
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  147. Ching TT, Maunakea AK, Jun P, Hong C, Zardo G, Pinkel D, Albertson DG, Fridlyand J, Mao JH, Shchors K, Weiss WA, Costello JF. Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3. Nat Genet. 2005 Jun; 37(6):645-51. PMID: 15895082.
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  148. Lim G, Wang S, Zeng Q, Sung B, Mao J. Spinal glucocorticoid receptors contribute to the development of morphine tolerance in rats. Anesthesiology. 2005 Apr; 102(4):832-7. PMID: 15791114.
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  149. zhang Y, Liu SP, Wei QY, Mao JP, Zhou ZG, Liao EY. [Paget disease of single bone--a case report]. Zhonghua Yi Xue Za Zhi. 2005 Mar 09; 85(9):647-8. PMID: 15949369.
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  150. Mao J. Glutamate transporter: an unexpected target for some antibiotics. Mol Pain. 2005 Feb 09; 1:5. PMID: 15813992; PMCID: PMC1074355.
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  151. Cui YF, Ding YQ, Zhang Y, Xu H, Jin W, Liu XL, Dong B, Mao JP, Mao BZ. [Apoptotic characteristics of spleen lymphocyte in mice irradiated by lethal dose and its relationship to the expression of Bax and Bcl-XL proteins]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2005 Feb; 17(2):109-12. PMID: 15698498.
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  152. Wang S, Lim G, Zeng Q, Sung B, Yang L, Mao J. Central glucocorticoid receptors modulate the expression and function of spinal NMDA receptors after peripheral nerve injury. J Neurosci. 2005 Jan 12; 25(2):488-95. PMID: 15647493.
    View in: PubMed
  153. Mao J. Central glucocorticoid receptor: a new role in the cellular mechanisms of neuropathic pain. Rev Neurosci. 2005; 16(3):233-8. PMID: 16329195.
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  154. Lim G, Wang S, Zeng Q, Sung B, Mao J. Evidence for a long-term influence on morphine tolerance after previous morphine exposure: role of neuronal glucocorticoid receptors. Pain. 2005 Mar; 114(1-2):81-92. PMID: 15733634.
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  155. Lim G, Wang S, Mao J. cAMP and protein kinase A contribute to the downregulation of spinal glutamate transporters after chronic morphine. Neurosci Lett. 2005 Mar 07; 376(1):9-13. PMID: 15694265.
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  156. Tang JZ, Mao JP, Yang ZF, Zhou ZG, Tang WL, Feng Q. [Effects of glimepiride and metformin on free fatty acid in patients with Type 2 diabetes mellitus]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2004 Dec; 29(6):631-4. PMID: 16114544.
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  157. Cohen SP, Chang AS, Larkin T, Mao J. The intravenous ketamine test: a predictive response tool for oral dextromethorphan treatment in neuropathic pain. Anesth Analg. 2004 Dec; 99(6):1753-9, table of contents. PMID: 15562066.
    View in: PubMed
  158. Cui YF, Ding YQ, Xu H, Jiang ZJ, Liu XL, Dong B, Mao JP. [Relationship between apoptosis of mouse thymic lymphocytes and expressions of bax, bcl-2 and bcl-XL after gamma-ray radiation with lethal dose]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2004 Nov; 20(6):750-3. PMID: 15555453.
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  159. Wang S, Lim G, Zeng Q, Sung B, Ai Y, Guo G, Yang L, Mao J. Expression of central glucocorticoid receptors after peripheral nerve injury contributes to neuropathic pain behaviors in rats. J Neurosci. 2004 Sep 29; 24(39):8595-605. PMID: 15456833.
    View in: PubMed
  160. Mao JH, To MD, Perez-Losada J, Wu D, Del Rosario R, Balmain A. Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression. Genes Dev. 2004 Aug 01; 18(15):1800-5. PMID: 15289454; PMCID: PMC517400.
    View in: PubMed, PubMed Central
  161. Mao JH, Chen ZM, Tang YM, Liang L, Du LZ, Zhang Y. [Regulation of CD3, CD4 and CD8 expressions on PMA-activated human peripheral T cells]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Mar; 33(2):155-9. PMID: 15067739.
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  162. Mao J. Opioid tolerance and neuroplasticity. Novartis Found Symp. 2004; 261:181-6; discussion 187-93. PMID: 15469051.
    View in: PubMed
  163. Ballantyne JC, Mao J. Opioid therapy for chronic pain. N Engl J Med. 2003 Nov 13; 349(20):1943-53. PMID: 14614170.
    View in: PubMed
  164. Cheng X, Mao JM, Bush R, Kopans DB, Moore RH, Chorlton M. Breast cancer detection by mapping hemoglobin concentration and oxygen saturation. Appl Opt. 2003 Nov 01; 42(31):6412-21. PMID: 14649285.
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  165. Lim G, Sung B, Ji RR, Mao J. Upregulation of spinal cannabinoid-1-receptors following nerve injury enhances the effects of Win 55,212-2 on neuropathic pain behaviors in rats. Pain. 2003 Sep; 105(1-2):275-83. PMID: 14499445.
    View in: PubMed
  166. Hord ED, Stojanovic MP, Vallejo R, Barna SA, Santiago-Palma J, Mao J. Multiple Bier blocks with labetalol for complex regional pain syndrome refractory to other treatments. J Pain Symptom Manage. 2003 Apr; 25(4):299-302. PMID: 12691679.
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  167. Sung B, Lim G, Mao J. Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats. J Neurosci. 2003 Apr 01; 23(7):2899-910. PMID: 12684477.
    View in: PubMed
  168. Mao J. Opioid-induced abnormal pain sensitivity: implications in clinical opioid therapy. Pain. 2002 Dec; 100(3):213-7. PMID: 12467992.
    View in: PubMed
  169. Mao J, Sung B, Ji RR, Lim G. Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity. J Neurosci. 2002 Sep 15; 22(18):8312-23. PMID: 12223586.
    View in: PubMed
  170. Mao J, Sung B, Ji RR, Lim G. Neuronal apoptosis associated with morphine tolerance: evidence for an opioid-induced neurotoxic mechanism. J Neurosci. 2002 Sep 01; 22(17):7650-61. PMID: 12196588.
    View in: PubMed
  171. Mao J. Translational pain research: bridging the gap between basic and clinical research. Pain. 2002 Jun; 97(3):183-7. PMID: 12044614.
    View in: PubMed
  172. Mao J, Chen LL. Gabapentin in pain management. Anesth Analg. 2000 Sep; 91(3):680-7. PMID: 10960399.
    View in: PubMed
  173. Mao J, Chen LL. Systemic lidocaine for neuropathic pain relief. Pain. 2000 Jul; 87(1):7-17. PMID: 10863041.
    View in: PubMed
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.