Harvard Catalyst Profiles

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Qian Qin, Ph.D.

Title
Institution
Department
Address

Biography
education and training
Massachusetts General Hospital, 149 13th street Charlestown Navy yardBioinformatics
Children's Hospital of Fudan University, Shanghai07/2019Bioinformatics
Department of Bioinformatics, Tongji Univerisity, ShanghaiPhD06/2017Bioinformatics

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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wei Y, Qin Q, Yan C, Hayes MN, Garcia SP, Xi H, Do D, Jin AH, Eng TC, McCarthy KM, Adhikari A, Onozato ML, Spentzos D, Neilsen GP, Iafrate AJ, Wexler LH, Pyle AD, Suvà ML, Dela Cruz F, Pinello L, Langenau DM. Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma. Nat Cancer. 2022 08; 3(8):961-975. PMID: 35982179.
    Citations: 1     Translation:HumansCells
  2. Yan C, Yang Q, Zhang S, Millar DG, Alpert EJ, Do D, Veloso A, Brunson DC, Drapkin BJ, Stanzione M, Scarfò I, Moore JC, Iyer S, Qin Q, Wei Y, McCarthy KM, Rawls JF, Dyson NJ, Cobbold M, Maus MV, Langenau DM. Single-cell imaging of T cell immunotherapy responses in vivo. J Exp Med. 2021 10 04; 218(10). PMID: 34415995; PMCID: PMC8383813.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  3. Wang L, Zhang Q, Qin Q, Trasanidis N, Vinyard M, Chen H, Pinello L. Current progress and potential opportunities to infer single-cell developmental trajectory and cell fate. Curr Opin Syst Biol. 2021 Jun; 26:1-11. PMID: 33997529; PMCID: PMC8117397.
    Citations: 1     
  4. Yao Y, Yang J, Qin Q, Tang C, Li Z, Chen L, Li K, Ren C, Chen L, Rao S. Functional annotation of genetic associations by transcriptome-wide association analysis provides insights into neutrophil development regulation. Commun Biol. 2020 12 18; 3(1):790. PMID: 33340029.
    Citations: 1     Translation:HumansCells
  5. Wang C, Sun D, Huang X, Wan C, Li Z, Han Y, Qin Q, Fan J, Qiu X, Xie Y, Meyer CA, Brown M, Tang M, Long H, Liu T, Liu XS. Integrative analyses of single-cell transcriptome and regulome using MAESTRO. Genome Biol. 2020 08 07; 21(1):198. PMID: 32767996.
    Citations: 43     Fields:    Translation:HumansCells
  6. Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, Shen Y, He Y, Mackiewicz M, Pauli-Behn F, Williams BA, Mortazavi A, Keller CA, Zhang XO, Elhajjajy SI, Huey J, Dickel DE, Snetkova V, Wei X, Wang X, Rivera-Mulia JC, Rozowsky J, Zhang J, Chhetri SB, Zhang J, Victorsen A, White KP, Visel A, Yeo GW, Burge CB, Lécuyer E, Gilbert DM, Dekker J, Rinn J, Mendenhall EM, Ecker JR, Kellis M, Klein RJ, Noble WS, Kundaje A, Guigó R, Farnham PJ, Cherry JM, Myers RM, Ren B, Graveley BR, Gerstein MB, Pennacchio LA, Snyder MP, Bernstein BE, Wold B, Hardison RC, Gingeras TR, Stamatoyannopoulos JA, Weng Z. Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature. 2020 07; 583(7818):699-710. PMID: 32728249; PMCID: PMC7410828.
    Citations: 404     Fields:    Translation:HumansAnimalsCells
  7. Snyder MP, Gingeras TR, Moore JE, Weng Z, Gerstein MB, Ren B, Hardison RC, Stamatoyannopoulos JA, Graveley BR, Feingold EA, Pazin MJ, Pagan M, Gilchrist DA, Hitz BC, Cherry JM, Bernstein BE, Mendenhall EM, Zerbino DR, Frankish A, Flicek P, Myers RM. Perspectives on ENCODE. Nature. 2020 07; 583(7818):693-698. PMID: 32728248; PMCID: PMC7410827.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  8. Wang H, Qian Y, Lu Y, Qin Q, Lu G, Cheng G, Zhang P, Yang L, Wu B, Zhou W. Clinical utility of 24-h rapid trio-exome sequencing for critically ill infants. NPJ Genom Med. 2020; 5:20. PMID: 32411386.
    Citations: 14     
  9. Liu B, Lu Y, Wu B, Yang L, Liu R, Wang H, Dong X, Li G, Qin Q, Zhou W. Survival Motor Neuron Gene Copy Number Analysis by Exome Sequencing: Assisting Spinal Muscular Atrophy Diagnosis and Carrier Screening. J Mol Diagn. 2020 05; 22(5):619-628. PMID: 32092542.
    Citations: 4     Fields:    Translation:HumansCells
  10. Qin Q, Fan J, Zheng R, Wan C, Mei S, Wu Q, Sun H, Brown M, Zhang J, Meyer CA, Liu XS. Lisa: inferring transcriptional regulators through integrative modeling of public chromatin accessibility and ChIP-seq data. Genome Biol. 2020 02 07; 21(1):32. PMID: 32033573; PMCID: PMC7007693.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  11. Ge MM, Gao YY, Wu BB, Yan K, Qin Q, Wang H, Zhou W, Yang L. Relationship between phenotype and genotype of 102 Chinese newborns with Prader-Willi syndrome. Mol Biol Rep. 2019 Oct; 46(5):4717-4724. PMID: 31270759.
    Citations: 5     Fields:    Translation:HumansCells
  12. Chen X, Yan K, Gao Y, Wang H, Chen G, Wu B, Qin Q, Yang L, Zhou W. Feeding difficulty is the dominant feature in 12 Chinese newborns with CHD7 pathogenic variants. BMC Med Genet. 2019 05 30; 20(1):93. PMID: 31146700; PMCID: PMC6543684.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  13. Zheng R, Wan C, Mei S, Qin Q, Wu Q, Sun H, Chen CH, Brown M, Zhang X, Meyer CA, Liu XS. Cistrome Data Browser: expanded datasets and new tools for gene regulatory analysis. Nucleic Acids Res. 2019 01 08; 47(D1):D729-D735. PMID: 30462313; PMCID: PMC6324081.
    Citations: 246     Fields:    Translation:HumansAnimalsCells
  14. Qian Y, Wu B, Lu Y, Dong X, Qin Q, Zhou W, Wang H. Early-onset infant epileptic encephalopathy associated with a de novo PPP3CA gene mutation. Cold Spring Harb Mol Case Stud. 2018 12; 4(6). PMID: 30455226; PMCID: PMC6318765.
    Citations: 4     Fields:    Translation:Humans
  15. Mei S, Meyer CA, Zheng R, Qin Q, Wu Q, Jiang P, Li B, Shi X, Wang B, Fan J, Shih C, Brown M, Zang C, Liu XS. Cistrome Cancer: A Web Resource for Integrative Gene Regulation Modeling in Cancer. Cancer Res. 2017 11 01; 77(21):e19-e22. PMID: 29092931; PMCID: PMC5826647.
    Citations: 86     Fields:    Translation:HumansCells
  16. Qin Q, Feng J. Imputation for transcription factor binding predictions based on deep learning. PLoS Comput Biol. 2017 02; 13(2):e1005403. PMID: 28234893; PMCID: PMC5345877.
    Citations: 28     Fields:    Translation:HumansCells
  17. Mei S, Qin Q, Wu Q, Sun H, Zheng R, Zang C, Zhu M, Wu J, Shi X, Taing L, Liu T, Brown M, Meyer CA, Liu XS. Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse. Nucleic Acids Res. 2017 01 04; 45(D1):D658-D662. PMID: 27789702; PMCID: PMC5210658.
    Citations: 237     Fields:    Translation:HumansAnimals
  18. Qin Q, Mei S, Wu Q, Sun H, Li L, Taing L, Chen S, Li F, Liu T, Zang C, Xu H, Chen Y, Meyer CA, Zhang Y, Brown M, Long HW, Liu XS. ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline. BMC Bioinformatics. 2016 Oct 03; 17(1):404. PMID: 27716038.
    Citations: 57     Fields:    Translation:Humans
  19. Wang S, Zang C, Xiao T, Fan J, Mei S, Qin Q, Wu Q, Li X, Xu K, He HH, Brown M, Meyer CA, Liu XS. Modeling cis-regulation with a compendium of genome-wide histone H3K27ac profiles. Genome Res. 2016 10; 26(10):1417-1429. PMID: 27466232; PMCID: PMC5052056.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  20. Ma J, Köster J, Qin Q, Hu S, Li W, Chen C, Cao Q, Wang J, Mei S, Liu Q, Xu H, Liu XS. CRISPR-DO for genome-wide CRISPR design and optimization. Bioinformatics. 2016 11 01; 32(21):3336-3338. PMID: 27402906.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  21. Zang C, Wang T, Deng K, Li B, Hu S, Qin Q, Xiao T, Zhang S, Meyer CA, He HH, Brown M, Liu JS, Xie Y, Liu XS. High-dimensional genomic data bias correction and data integration using MANCIE. Nat Commun. 2016 Apr 13; 7:11305. PMID: 27072482.
    Citations: 14     Fields:    Translation:HumansCells
  22. Xu H, Xu K, He HH, Zang C, Chen CH, Chen Y, Qin Q, Wang S, Wang C, Hu S, Li F, Long H, Brown M, Liu XS. Integrative Analysis Reveals the Transcriptional Collaboration between EZH2 and E2F1 in the Regulation of Cancer-Related Gene Expression. Mol Cancer Res. 2016 Feb; 14(2):163-172. PMID: 26659825.
    Citations: 20     Fields:    Translation:HumansCells
  23. Zheng X, Zhao Q, Wu HJ, Li W, Wang H, Meyer CA, Qin QA, Xu H, Zang C, Jiang P, Li F, Hou Y, He J, Wang J, Wang J, Zhang P, Zhang Y, Liu XS. MethylPurify: tumor purity deconvolution and differential methylation detection from single tumor DNA methylomes. Genome Biol. 2014 Aug 07; 15(8):419. PMID: 25103624.
    Citations: 41     Fields:    Translation:HumansCells
  24. Wang Q, Huang J, Sun H, Liu J, Wang J, Wang Q, Qin Q, Mei S, Zhao C, Yang X, Liu XS, Zhang Y. CR Cistrome: a ChIP-Seq database for chromatin regulators and histone modification linkages in human and mouse. Nucleic Acids Res. 2014 Jan; 42(Database issue):D450-8. PMID: 24253304.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.