Harvard Catalyst Profiles

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Moustafa Algamal, Ph.D.

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Roskamp Institute, USAPh.D01/2019Neuroscience
McMaster University, CanadaMasters07/2014Chemical Biology
The German University in Cairo, EgyptBachelor07/2009Pharmacy
Trainee Professional Development Award
Caring for Dependent(s) Travel Awards
Impact award
Academic Award
Internship Award
2004 - 2009


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. A2021001F (Moustafa Algamal) Jul 1, 2021 - Jun 30, 2023
    BrightFocus Foundation
    Targeting Sleep Deficits to Restore Memory Function in Alzheimer's Disease
    Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Algamal M, Russ AN, Miller MR, Hou SS, Maci M, Munting LP, Zhao Q, Gerashchenko D, Bacskai BJ, Kastanenka KV. Reduced excitatory neuron activity and interneuron-type-specific deficits in a mouse model of Alzheimer's disease. Commun Biol. 2022 12 02; 5(1):1323. PMID: 36460716; PMCID: PMC9718858.
    Citations: 1     Translation:AnimalsCells
  2. Lynch CE, Eisenbaum M, Algamal M, Balbi M, Ferguson S, Mouzon B, Saltiel N, Ojo J, Diaz-Arrastia R, Mullan M, Crawford F, Bachmeier C. Impairment of cerebrovascular reactivity in response to hypercapnic challenge in a mouse model of repetitive mild traumatic brain injury. J Cereb Blood Flow Metab. 2021 06; 41(6):1362-1378. PMID: 33050825.
    Citations: 4     Fields:    Translation:Animals
  3. Pearson A, Ajoy R, Crynen G, Reed JM, Algamal M, Mullan M, Purohit D, Crawford F, Ojo JO. Molecular abnormalities in autopsied brain tissue from the inferior horn of the lateral ventricles of nonagenarians and Alzheimer disease patients. BMC Neurol. 2020 Aug 27; 20(1):317. PMID: 32854643.
    Citations: 5     Fields:    Translation:Humans
  4. Algamal M, Pearson AJ, Hahn-Townsend C, Burca I, Mullan M, Crawford F, Ojo JO. Repeated unpredictable stress and social isolation induce chronic HPA axis dysfunction and persistent abnormal fear memory. Prog Neuropsychopharmacol Biol Psychiatry. 2021 01 10; 104:110035. PMID: 32682873.
    Citations: 2     Fields:    Translation:Animals
  5. Ojo JO, Crynen G, Algamal M, Vallabhaneni P, Leary P, Mouzon B, Reed JM, Mullan M, Crawford F. Unbiased Proteomic Approach Identifies Pathobiological Profiles in the Brains of Preclinical Models of Repetitive Mild Traumatic Brain Injury, Tauopathy, and Amyloidosis. ASN Neuro. 2020 Jan-Dec; 12:1759091420914768. PMID: 32241177.
    Citations: 4     Fields:    Translation:Animals
  6. Algamal M, Saltiel N, Pearson AJ, Ager B, Burca I, Mouzon B, Diamond DM, Mullan M, Ojo JO, Crawford F. Impact of Repetitive Mild Traumatic Brain Injury on Behavioral and Hippocampal Deficits in a Mouse Model of Chronic Stress. J Neurotrauma. 2019 09 01; 36(17):2590-2607. PMID: 30963958.
    Citations: 5     Fields:    Translation:Animals
  7. Ojo JO, Algamal M, Leary P, Abdullah L, Mouzon B, Evans JE, Mullan M, Crawford F. Converging and Differential Brain Phospholipid Dysregulation in the Pathogenesis of Repetitive Mild Traumatic Brain Injury and Alzheimer's Disease. Front Neurosci. 2019; 13:103. PMID: 30837829; PMCID: PMC6390207.
    Citations: 12     
  8. Muza P, Bachmeier C, Mouzon B, Algamal M, Rafi NG, Lungmus C, Abdullah L, Evans JE, Ferguson S, Mullan M, Crawford F, Ojo JO. APOE Genotype Specific Effects on the Early Neurodegenerative Sequelae Following Chronic Repeated Mild Traumatic Brain Injury. Neuroscience. 2019 04 15; 404:297-313. PMID: 30711612.
    Citations: 11     Fields:    Translation:Animals
  9. Ojo JO, Crynen G, Reed JM, Ajoy R, Vallabhaneni P, Algamal M, Leary P, Rafi NG, Mouzon B, Mullan M, Crawford F. Unbiased Proteomic Approach Identifies Unique and Coincidental Plasma Biomarkers in Repetitive mTBI and AD Pathogenesis. Front Aging Neurosci. 2018; 10:405. PMID: 30618712; PMCID: PMC6305374.
    Citations: 7     
  10. Ojo JO, Algamal M, Leary P, Abdullah L, Mouzon B, Evans JE, Mullan M, Crawford F. Disruption in Brain Phospholipid Content in a Humanized Tau Transgenic Model Following Repetitive Mild Traumatic Brain Injury. Front Neurosci. 2018; 12:893. PMID: 30564087; PMCID: PMC6288299.
    Citations: 6     
  11. Ojo JO, Leary P, Lungmus C, Algamal M, Mouzon B, Bachmeier C, Mullan M, Stewart W, Crawford F. Subchronic Pathobiological Response Following Chronic Repetitive Mild Traumatic Brain Injury in an Aged Preclinical Model of Amyloid Pathogenesis. J Neuropathol Exp Neurol. 2018 12 01; 77(12):1144-1162. PMID: 30395237.
    Citations: 1     Fields:    Translation:Animals
  12. Algamal M, Ojo JO, Lungmus CP, Muza P, Cammarata C, Owens MJ, Mouzon BC, Diamond DM, Mullan M, Crawford F. Chronic Hippocampal Abnormalities and Blunted HPA Axis in an Animal Model of Repeated Unpredictable Stress. Front Behav Neurosci. 2018; 12:150. PMID: 30079015; PMCID: PMC6062757.
    Citations: 9     
  13. Mouzon B, Saltiel N, Ferguson S, Ojo J, Lungmus C, Lynch C, Algamal M, Morin A, Carper B, Bieler G, Mufson EJ, Stewart W, Mullan M, Crawford F. Impact of age on acute post-TBI neuropathology in mice expressing humanized tau: a Chronic Effects of Neurotrauma Consortium Study. Brain Inj. 2018; 32(10):1285-1294. PMID: 29927671.
    Citations: 12     Fields:    Translation:HumansAnimals
  14. Algamal M, Ahmed R, Jafari N, Ahsan B, Ortega J, Melacini G. Atomic-resolution map of the interactions between an amyloid inhibitor protein and amyloid ß (Aß) peptides in the monomer and protofibril states. J Biol Chem. 2017 10 20; 292(42):17158-17168. PMID: 28798235.
    Citations: 17     Fields:    Translation:HumansCells
  15. Ojo JO, Mouzon B, Algamal M, Leary P, Lynch C, Abdullah L, Evans J, Mullan M, Bachmeier C, Stewart W, Crawford F. Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers. J Neuropathol Exp Neurol. 2016 07; 75(7):636-55. PMID: 27251042; PMCID: PMC4913432.
    Citations: 54     Fields:    Translation:HumansAnimals
  16. Algamal M, Milojevic J, Jafari N, Zhang W, Melacini G. Mapping the interactions between the Alzheimer's Aß-peptide and human serum albumin beyond domain resolution. Biophys J. 2013 Oct 01; 105(7):1700-9. PMID: 24094411.
    Citations: 16     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.