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Nathaniel B. Langer, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Osho AA, Moonsamy P, Ethridge BR, Leya GA, D'Alessandro DA, Jassar AS, Villavicencio MA, Melnitchouk SI, Tolis G, Langer NB, Funamoto M, Li SS, Colon KM, Mohan N, Locascio JJ, Lubitz SA, Akeju O, Sundt TM. Rationale and Design of the Randomized Controlled Trial of New Oral Anticoagulants vs. Warfarin for post Cardiac Surgery Atrial Fibrillation: The NEW-AF Trial. Ann Surg. 2020 Sep 01. PMID: 32889881.
    Citations:    
  2. Tanguturi VK, Lindman BR, Pibarot P, Passeri JJ, Kapadia S, Mack MJ, Inglessis I, Langer NB, Sundt TM, Hung J, Elmariah S. Managing Severe Aortic Stenosis in the COVID-19 Era. JACC Cardiovasc Interv. 2020 08 24; 13(16):1937-1944. PMID: 32484159.
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  3. Langer NB, Vlahakes GJ. Commentary: A step toward solving a stubborn problem…maybe. J Thorac Cardiovasc Surg. 2020 Feb 19. PMID: 32173101.
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  4. Langer NB, Vlahakes GJ. Commentary: Myocardial protection is a process, not an event. J Thorac Cardiovasc Surg. 2019 Sep 30. PMID: 31653421.
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  5. Langer NB, Takayama H. Commentary: Thinking outside the (cardiac) box. J Thorac Cardiovasc Surg. 2019 06; 157(6):e363-e364. PMID: 30630602.
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  6. Langer NB, Ando M, Simpson M, van Boxtel BS, Sorabella RA, Patel V, George I, Smith CR, Takayama H. Influence of left ventricular ejection fraction on morbidity and mortality after aortic root replacement. J Thorac Cardiovasc Surg. 2019 10; 158(4):984-991.e1. PMID: 30578054.
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  7. Boulate D, Fabre D, Langer NB, Fadel E. Ascending aorta, aortic arch and supra-aortic vessels rupture in blunt thoracic trauma. Interact Cardiovasc Thorac Surg. 2018 08 01; 27(2):304-306. PMID: 29514278.
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  8. Hambley BC, Rahman RA, Reback M, O'Riordan MA, Langer N, Gilkeson RC, Ginwalla M, Little JA, Schilz R. Intracardiac or intrapulmonary shunts were present in at least 35% of adults with homozygous sickle cell disease followed in an outpatient clinic. Haematologica. 2019 01; 104(1):e1-e3. PMID: 30006446.
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  9. Langer NB, Solowiejczyk D, Fahey JT, Torres A, Bacha E, Kalfa D. Modified technique for Melody valve implantation in the mitral position. J Thorac Cardiovasc Surg. 2018 09; 156(3):1190-1191. PMID: 29709362.
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  10. Provost B, Missenard G, Pricopi C, Mercier O, Mussot S, Fabre D, Langer N, Mir O, Le Pechoux C, Dartevelle P, Fadel E. Ewing Sarcoma of the Chest Wall: Prognostic Factors of Multimodal Therapy Including En Bloc Resection. Ann Thorac Surg. 2018 07; 106(1):207-213. PMID: 29551629.
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  11. Langer NB, Takayama H. Albumin (but not Alvin) and the chipmunks help protect our brain! J Thorac Cardiovasc Surg. 2018 08; 156(2):539-540. PMID: 29602420.
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  12. Noly PE, Haddad F, Arthur-Ataam J, Langer N, Dorfmüller P, Loisel F, Guihaire J, Decante B, Lamrani L, Fadel E, Mercier O. The importance of capillary density-stroke work mismatch for right ventricular adaptation to chronic pressure overload. J Thorac Cardiovasc Surg. 2017 12; 154(6):2070-2079. PMID: 28712579.
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  13. Langer NB, Hamid NB, Nazif TM, Khalique OK, Vahl TP, White J, Terre J, Hastings R, Leung D, Hahn RT, Leon M, Kodali S, George I. Injuries to the Aorta, Aortic Annulus, and Left Ventricle During Transcatheter Aortic Valve Replacement: Management and Outcomes. Circ Cardiovasc Interv. 2017 01; 10(1). PMID: 28039322.
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  14. Mercier O, Arthur Ataam J, Langer NB, Dorfmüller P, Lamrani L, Lecerf F, Decante B, Dartevelle P, Eddahibi S, Fadel E. Abnormal pulmonary endothelial cells may underlie the enigmatic pathogenesis of chronic thromboembolic pulmonary hypertension. J Heart Lung Transplant. 2017 Mar; 36(3):305-314. PMID: 27793518.
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  15. Rotz SJ, Ann O'riordan M, Kim C, Langer N, Cruz C, Schilz R, Lance C, Little JA. Nocturnal hemoglobin desaturation is associated with reticulocytosis in adults with sickle cell disease and is independent of obstructive sleep apnea. Am J Hematol. 2016 Sep; 91(9):E355-6. PMID: 27220489.
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  16. Langer NB, Mercier O, Fabre D, Lawton J, Mussot S, Dartevelle P, Fadel E. Outcomes After Resection of T4 Non-Small Cell Lung Cancer Using Cardiopulmonary Bypass. Ann Thorac Surg. 2016 Sep; 102(3):902-910. PMID: 27209605.
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  17. Langer NB, Nazif TM, Powers ME, Fukuhara S, Borger MA, George I. Cardiogenic Shock From Coronary Compression: A Difficult Diagnosis But Easy Fix. Ann Thorac Surg. 2016 Apr; 101(4):e111-3. PMID: 27000612.
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  18. Langer NB, Argenziano M. Minimally Invasive Cardiovascular Surgery: Incisions and Approaches. Methodist Debakey Cardiovasc J. 2016 Jan-Mar; 12(1):4-9. PMID: 27127555.
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  19. Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, Wittig JG, Chen W, Lu W, Galy B, Schlaeger TM, Hentze MW, Ward DM, Kaplan J, Eisenstein RS, Peters LL, Paw BH. Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria. J Biol Chem. 2014 Mar 14; 289(11):7835-43. PMID: 24509859.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  20. Bayeva M, Khechaduri A, Wu R, Burke MA, Wasserstrom JA, Singh N, Liesa M, Shirihai OS, Langer NB, Paw BH, Ardehali H. ATP-binding cassette B10 regulates early steps of heme synthesis. Circ Res. 2013 Jul 19; 113(3):279-87. PMID: 23720443.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  21. Shah DI, Takahashi-Makise N, Cooney JD, Li L, Schultz IJ, Pierce EL, Narla A, Seguin A, Hattangadi SM, Medlock AE, Langer NB, Dailey TA, Hurst SN, Faccenda D, Wiwczar JM, Heggers SK, Vogin G, Chen W, Chen C, Campagna DR, Brugnara C, Zhou Y, Ebert BL, Danial NN, Fleming MD, Ward DM, Campanella M, Dailey HA, Kaplan J, Paw BH. Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts. Nature. 2012 Nov 22; 491(7425):608-12. PMID: 23135403.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  22. Wang Y, Langer NB, Shaw GC, Yang G, Li L, Kaplan J, Paw BH, Bloomer JR. Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria. Exp Hematol. 2011 Jul; 39(7):784-94. PMID: 21627978.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  23. Leaf DE, Langer NB, Markowski M, Garratty G, Diuguid DL. A severe case of cefoxitin-induced immune hemolytic anemia. Acta Haematol. 2010; 124(4):197-9. PMID: 21042010.
    Citations:    Fields:    Translation:Humans
  24. Chen W, Paradkar PN, Li L, Pierce EL, Langer NB, Takahashi-Makise N, Hyde BB, Shirihai OS, Ward DM, Kaplan J, Paw BH. Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38):16263-8. PMID: 19805291.
    Citations: 67     Fields:    Translation:AnimalsCells
  25. Amigo JD, Ackermann GE, Cope JJ, Yu M, Cooney JD, Ma D, Langer NB, Shafizadeh E, Shaw GC, Horsely W, Trede NS, Davidson AJ, Barut BA, Zhou Y, Wojiski SA, Traver D, Moran TB, Kourkoulis G, Hsu K, Kanki JP, Shah DI, Lin HF, Handin RI, Cantor AB, Paw BH. The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish. Blood. 2009 Nov 19; 114(21):4654-63. PMID: 19729519.
    Citations: 24     Fields:    Translation:Animals
  26. Johnson HJ, Gandhi MJ, Shafizadeh E, Langer NB, Pierce EL, Paw BH, Gilligan DM, Drachman JG. In vivo inactivation of MASTL kinase results in thrombocytopenia. Exp Hematol. 2009 Aug; 37(8):901-8. PMID: 19460416.
    Citations: 7     Fields:    Translation:AnimalsCells
  27. Dooley KA, Fraenkel PG, Langer NB, Schmid B, Davidson AJ, Weber G, Chiang K, Foott H, Dwyer C, Wingert RA, Zhou Y, Paw BH, Zon LI. montalcino, A zebrafish model for variegate porphyria. Exp Hematol. 2008 Sep; 36(9):1132-42. PMID: 18550261.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  28. Woo AJ, Moran TB, Schindler YL, Choe SK, Langer NB, Sullivan MR, Fujiwara Y, Paw BH, Cantor AB. Identification of ZBP-89 as a novel GATA-1-associated transcription factor involved in megakaryocytic and erythroid development. Mol Cell Biol. 2008 Apr; 28(8):2675-89. PMID: 18250154.
    Citations: 37     Fields:    Translation:AnimalsCells
  29. Langer N, Beach D, Lindenbaum ES. Novel hyperactive mitogen to endothelial cells: human decidual NKG5. Am J Reprod Immunol. 1999 Nov; 42(5):263-72. PMID: 10584980.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.