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profileElizabeth Austen Lawson, M.D.

TitleAssociate Professor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Neuroendocrine Unit, BUL 457-D
55 Fruit St
Boston MA 02114
Phone617/726-2241
Fax617/726-5072
vCardDownload vCard (login for email)

Collapse Mentoring 
Collapse completed student projects
Relationship between dysregulation of oxytocin and deficits in social cognition in anorexia nervosa
Summer, 06/09/14 - 07/29/14

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01DK109932     (LAWSON, ELIZABETH AUSTEN)May 1, 2017 - Apr 30, 2021
NIH/NIDDK
Oxytocin and Weight Loss in Humans
Role: Principal Investigator

R01MH108595     (THOMAS, JENNIFER JOANNE)Mar 15, 2016 - Feb 28, 2021
NIH/NIMH
Neurobiological and Behavioral Risk Mechanisms of Youth Avoidant/Restrictive Eating Trajectories
Role: Principal Investigator

R01MH103402     (MISRA, MADHUSMITA)Apr 1, 2014 - Mar 31, 2019
NIH/NIMH
Homeostatic and Hedonic Food Motivation Underlying Eating Disorder Trajectories
Role: Co-Principal Investigator

K23MH092560     (LAWSON, ELIZABETH AUSTEN)Jul 6, 2011 - Jun 30, 2016
NIH/NIMH
Appetite-regulating Hormones and Neurocircuitry in Anorexia Nervosa
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Dichtel LE, Lawson EA, Schorr M, Meenaghan E, Paskal ML, Eddy KT, Pinna G, Nelson M, Rasmusson AM, Klibanski A, Miller KK. Neuroactive Steroids and Affective Symptoms in Women Across the Weight Spectrum. Neuropsychopharmacology. 2017 Nov 01. PMID: 29090684.
    View in: PubMed
  2. Schmelkin C, Plessow F, Thomas JJ, Gray EK, Marengi DA, Pulumo R, Silva L, Miller KK, Hadjikhani N, Franko DL, Eddy KT, Lawson EA. Low oxytocin levels are related to alexithymia in anorexia nervosa. Int J Eat Disord. 2017 Nov; 50(11):1332-1338. PMID: 29044580.
    View in: PubMed
  3. Lawson EA. The effects of oxytocin on eating behaviour and metabolism in humans. Nat Rev Endocrinol. 2017 Sep 29. PMID: 28960210.
    View in: PubMed
  4. Plessow F, Marengi DA, Perry SK, Felicione JM, Franklin R, Holmes TM, Holsen LM, Makris N, Deckersbach T, Lawson EA. Effects of Intranasal Oxytocin on the Blood Oxygenation Level-Dependent Signal in Food Motivation and Cognitive Control Pathways in Overweight and Obese Men. Neuropsychopharmacology. 2017 Sep 20. PMID: 28930284.
    View in: PubMed
  5. Silva PPB, Amlashi FG, Yu EW, Pulaski-Liebert KJ, Gerweck AV, Fazeli PK, Lawson E, Nachtigall LB, Biller BMK, Miller KK, Klibanski A, Bouxsein M, Tritos NA. Bone microarchitecture and estimated bone strength in men with active acromegaly. Eur J Endocrinol. 2017 Nov; 177(5):409-420. PMID: 28780520.
    View in: PubMed
  6. Schorr M, Marengi DA, Pulumo RL, Yu E, Eddy KT, Klibanski A, Miller KK, Lawson EA. Oxytocin and Its Relationship to Body Composition, Bone Mineral Density, and Hip Geometry Across the Weight Spectrum. J Clin Endocrinol Metab. 2017 Aug 01; 102(8):2814-2824. PMID: 28586943.
    View in: PubMed
  7. Baskaran C, Plessow F, Silva L, Asanza E, Marengi D, Eddy KT, Sluss PM, Johnson ML, Misra M, Lawson EA. Oxytocin secretion is pulsatile in men and is related to social-emotional functioning. Psychoneuroendocrinology. 2017 Nov; 85:28-34. PMID: 28800490.
    View in: PubMed
  8. Baskaran C, Cunningham B, Plessow F, Singhal V, Woolley R, Ackerman KE, Slattery M, Lee H, Lawson EA, Eddy K, Misra M. Estrogen Replacement Improves Verbal Memory and Executive Control in Oligomenorrheic/Amenorrheic Athletes in a Randomized Controlled Trial. J Clin Psychiatry. 2017 May; 78(5):e490-e497. PMID: 28297591.
    View in: PubMed
  9. Bachmann KN, Schorr M, Bruno AG, Bredella MA, Lawson EA, Gill CM, Singhal V, Meenaghan E, Gerweck AV, Slattery M, Eddy KT, Ebrahimi S, Koman SL, Greenblatt JM, Keane RJ, Weigel T, Misra M, Bouxsein ML, Klibanski A, Miller KK. Vertebral Volumetric Bone Density and Strength Are Impaired in Women With Low-Weight and Atypical Anorexia Nervosa. J Clin Endocrinol Metab. 2017 Jan 01; 102(1):57-68. PMID: 27732336.
    View in: PubMed
  10. Micali N, Crous-Bou M, Treasure J, Lawson EA. Association Between Oxytocin Receptor Genotype, Maternal Care, and Eating Disorder Behaviours in a Community Sample of Women. Eur Eat Disord Rev. 2017 Jan; 25(1):19-25. PMID: 27862641.
    View in: PubMed
  11. Afinogenova Y, Schmelkin C, Plessow F, Thomas JJ, Pulumo R, Micali N, Miller KK, Eddy KT, Lawson EA. Low Fasting Oxytocin Levels Are Associated With Psychopathology in Anorexia Nervosa in Partial Recovery. J Clin Psychiatry. 2016 Nov; 77(11):e1483-e1490. PMID: 28076675.
    View in: PubMed
  12. Schorr M, Thomas JJ, Eddy KT, Dichtel LE, Lawson EA, Meenaghan E, Lederfine Paskal M, Fazeli PK, Faje AT, Misra M, Klibanski A, Miller KK. Bone density, body composition, and psychopathology of anorexia nervosa spectrum disorders in DSM-IV vs DSM-5. Int J Eat Disord. 2017 Apr; 50(4):343-351. PMID: 27527115.
    View in: PubMed
  13. Baskaran C, Eddy KT, Miller KK, Meenaghan E, Misra M, Lawson EA. Leptin secretory dynamics and associated disordered eating psychopathology across the weight spectrum. Eur J Endocrinol. 2016 Apr; 174(4):503-12. PMID: 26903591; PMCID: PMC4764871.
  14. Bachmann KN, Bruno AG, Bredella MA, Schorr M, Lawson EA, Gill CM, Singhal V, Meenaghan E, Gerweck AV, Eddy KT, Ebrahimi S, Koman SL, Greenblatt JM, Keane RJ, Weigel T, Dechant E, Misra M, Klibanski A, Bouxsein ML, Miller KK. Vertebral Strength and Estimated Fracture Risk Across the BMI Spectrum in Women. J Bone Miner Res. 2016 Feb; 31(2):281-8. PMID: 26332401; PMCID: PMC4833882 [Available on 02/01/17].
  15. Schorr M, Lawson EA, Dichtel LE, Klibanski A, Miller KK. Cortisol Measures Across the Weight Spectrum. J Clin Endocrinol Metab. 2015 Sep; 100(9):3313-21. PMID: 26171799; PMCID: PMC4570173.
  16. Lawson EA. Correction: Postprandial oxytocin secretion is associated with severity of anxiety and depressive symptoms in anorexia nervosa. J Clin Psychiatry. 2015 05; 76(5):666. PMID: 26035205.
    View in: PubMed
  17. Lawson EA, Marengi DA, DeSanti RL, Holmes TM, Schoenfeld DA, Tolley CJ. Oxytocin reduces caloric intake in men. Obesity (Silver Spring). 2015 May; 23(5):950-6. PMID: 25865294; PMCID: PMC4414748 [Available on 05/01/16].
  18. Backeljauw PF, Miller BS, Dutailly P, Houchard A, Lawson E, Hale DE, Reiner B, Sperling MA. Recombinant human growth hormone plus recombinant human insulin-like growth factor-1 coadministration therapy in short children with low insulin-like growth factor-1 and growth hormone sufficiency: results from a randomized, multicenter, open-label, parallel-group, active treatment-controlled trial. Horm Res Paediatr. 2015; 83(4):268-79. PMID: 25765099.
    View in: PubMed
  19. Neumeyer AM, O'Rourke JA, Massa A, Lee H, Lawson EA, McDougle CJ, Misra M. Brief report: bone fractures in children and adults with autism spectrum disorders. J Autism Dev Disord. 2015 Mar; 45(3):881-7. PMID: 25193141; PMCID: PMC4590779.
  20. Eddy KT, Lawson EA, Meade C, Meenaghan E, Horton SE, Misra M, Klibanski A, Miller KK. Appetite regulatory hormones in women with anorexia nervosa: binge-eating/purging versus restricting type. J Clin Psychiatry. 2015 Jan; 76(1):19-24. PMID: 25098834; PMCID: PMC4408926.
  21. Bachmann KN, Fazeli PK, Lawson EA, Russell BM, Riccio AD, Meenaghan E, Gerweck AV, Eddy K, Holmes T, Goldstein M, Weigel T, Ebrahimi S, Mickley D, Gleysteen S, Bredella MA, Klibanski A, Miller KK. Comparison of hip geometry, strength, and estimated fracture risk in women with anorexia nervosa and overweight/obese women. J Clin Endocrinol Metab. 2014 Dec; 99(12):4664-73. PMID: 25062461; PMCID: PMC4255123.
  22. Singhal V, Lawson EA, Ackerman KE, Fazeli PK, Clarke H, Lee H, Eddy K, Marengi DA, Derrico NP, Bouxsein ML, Misra M. Irisin levels are lower in young amenorrheic athletes compared with eumenorrheic athletes and non-athletes and are associated with bone density and strength estimates. PLoS One. 2014; 9(6):e100218. PMID: 24926783; PMCID: PMC4057451.
  23. Holsen LM, Lawson EA, Christensen K, Klibanski A, Goldstein JM. Abnormal relationships between the neural response to high- and low-calorie foods and endogenous acylated ghrelin in women with active and weight-recovered anorexia nervosa. Psychiatry Res. 2014 Aug 30; 223(2):94-103. PMID: 24862390; PMCID: PMC4090258.
  24. Hoge EA, Anderson E, Lawson EA, Bui E, Fischer LE, Khadge SD, Barrett LF, Simon NM. Gender moderates the effect of oxytocin on social judgments. Hum Psychopharmacol. 2014 May; 29(3):299-304. PMID: 24911580.
    View in: PubMed
  25. Lawson EA, Ackerman KE, Slattery M, Marengi DA, Clarke H, Misra M. Oxytocin secretion is related to measures of energy homeostasis in young amenorrheic athletes. J Clin Endocrinol Metab. 2014 May; 99(5):E881-5. PMID: 24606095; PMCID: PMC4010698.
  26. Lawson EA, Holsen LM, Desanti R, Santin M, Meenaghan E, Herzog DB, Goldstein JM, Klibanski A. Increased hypothalamic-pituitary-adrenal drive is associated with decreased appetite and hypoactivation of food-motivation neurocircuitry in anorexia nervosa. Eur J Endocrinol. 2013 Nov; 169(5):639-47. PMID: 23946275; PMCID: PMC3807591.
  27. Lawson EA, Holsen LM, Santin M, DeSanti R, Meenaghan E, Eddy KT, Herzog DB, Goldstein JM, Klibanski A. Postprandial oxytocin secretion is associated with severity of anxiety and depressive symptoms in anorexia nervosa. J Clin Psychiatry. 2013 May; 74(5):e451-7. PMID: 23759466; PMCID: PMC3731039.
  28. Lawson EA, Ackerman KE, Estella NM, Guereca G, Pierce L, Sluss PM, Bouxsein ML, Klibanski A, Misra M. Nocturnal oxytocin secretion is lower in amenorrheic athletes than nonathletes and associated with bone microarchitecture and finite element analysis parameters. Eur J Endocrinol. 2013 Mar; 168(3):457-64. PMID: 23258269; PMCID: PMC3679669.
  29. Lawson EA, Fazeli PK, Calder G, Putnam H, Misra M, Meenaghan E, Miller KK, Klibanski A. Plasma sodium level is associated with bone loss severity in women with anorexia nervosa: a cross-sectional study. J Clin Psychiatry. 2012 Nov; 73(11):e1379-83. PMID: 23218167; PMCID: PMC3729037.
  30. Holsen LM, Lawson EA, Blum J, Ko E, Makris N, Fazeli PK, Klibanski A, Goldstein JM. Food motivation circuitry hypoactivation related to hedonic and nonhedonic aspects of hunger and satiety in women with active anorexia nervosa and weight-restored women with anorexia nervosa. J Psychiatry Neurosci. 2012 Sep; 37(5):322-32. PMID: 22498079; PMCID: PMC3447131.
  31. Lawson EA, Holsen LM, Santin M, Meenaghan E, Eddy KT, Becker AE, Herzog DB, Goldstein JM, Klibanski A. Oxytocin secretion is associated with severity of disordered eating psychopathology and insular cortex hypoactivation in anorexia nervosa. J Clin Endocrinol Metab. 2012 Oct; 97(10):E1898-908. PMID: 22872688; PMCID: PMC3674290.
  32. Hoge EA, Lawson EA, Metcalf CA, Keshaviah A, Zak PJ, Pollack MH, Simon NM. Plasma oxytocin immunoreactive products and response to trust in patients with social anxiety disorder. Depress Anxiety. 2012 Nov; 29(11):924-30. PMID: 22807189; PMCID: PMC3751166.
  33. Fazeli PK, Calder GL, Miller KK, Misra M, Lawson EA, Meenaghan E, Lee H, Herzog D, Klibanski A. Psychotropic medication use in anorexia nervosa between 1997 and 2009. Int J Eat Disord. 2012 Dec; 45(8):970-6. PMID: 22733643; PMCID: PMC3726215.
  34. Lawson EA, Miller KK, Blum JI, Meenaghan E, Misra M, Eddy KT, Herzog DB, Klibanski A. Leptin levels are associated with decreased depressive symptoms in women across the weight spectrum, independent of body fat. Clin Endocrinol (Oxf). 2012 Apr; 76(4):520-5. PMID: 21781144; PMCID: PMC3296868.
  35. Lawson EA, Donoho DA, Blum JI, Meenaghan EM, Misra M, Herzog DB, Sluss PM, Miller KK, Klibanski A. Decreased nocturnal oxytocin levels in anorexia nervosa are associated with low bone mineral density and fat mass. J Clin Psychiatry. 2011 Nov; 72(11):1546-51. PMID: 21903023; PMCID: PMC3731046.
  36. Miller KK, Meenaghan E, Lawson EA, Misra M, Gleysteen S, Schoenfeld D, Herzog D, Klibanski A. Effects of risedronate and low-dose transdermal testosterone on bone mineral density in women with anorexia nervosa: a randomized, placebo-controlled study. J Clin Endocrinol Metab. 2011 Jul; 96(7):2081-8. PMID: 21525157; PMCID: PMC3135194.
  37. Lawson EA, Eddy KT, Donoho D, Misra M, Miller KK, Meenaghan E, Lydecker J, Herzog D, Klibanski A. Appetite-regulating hormones cortisol and peptide YY are associated with disordered eating psychopathology, independent of body mass index. Eur J Endocrinol. 2011 Feb; 164(2):253-61. PMID: 21098684; PMCID: PMC3677777.
  38. Misra M, Le Clair M, Mendes N, Miller KK, Lawson E, Meenaghan E, Weigel T, Ebrahimi S, Herzog DB, Klibanski A. Use of SSRIs may Impact Bone Density in Adolescent and Young Women with Anorexia Nervosa. CNS Spectr. 2010 Sep; 15(9):579-586. PMID: 24790401.
    View in: PubMed
  39. Fazeli PK, Lawson EA, Prabhakaran R, Miller KK, Donoho DA, Clemmons DR, Herzog DB, Misra M, Klibanski A. Effects of recombinant human growth hormone in anorexia nervosa: a randomized, placebo-controlled study. J Clin Endocrinol Metab. 2010 Nov; 95(11):4889-97. PMID: 20668047; PMCID: PMC2968733.
  40. Brick DJ, Gerweck AV, Meenaghan E, Lawson EA, Misra M, Fazeli P, Johnson W, Klibanski A, Miller KK. Determinants of IGF1 and GH across the weight spectrum: from anorexia nervosa to obesity. Eur J Endocrinol. 2010 Aug; 163(2):185-91. PMID: 20501597; PMCID: PMC2953770.
  41. Wojcik MH, Meenaghan E, Lawson EA, Misra M, Klibanski A, Miller KK. Reduced amylin levels are associated with low bone mineral density in women with anorexia nervosa. Bone. 2010 Mar; 46(3):796-800. PMID: 19931436; PMCID: PMC2824019.
  42. Lawson EA, Donoho D, Miller KK, Misra M, Meenaghan E, Lydecker J, Wexler T, Herzog DB, Klibanski A. Hypercortisolemia is associated with severity of bone loss and depression in hypothalamic amenorrhea and anorexia nervosa. J Clin Endocrinol Metab. 2009 Dec; 94(12):4710-6. PMID: 19837921; PMCID: PMC2795653.
  43. Lawson EA, Miller KK, Bredella MA, Phan C, Misra M, Meenaghan E, Rosenblum L, Donoho D, Gupta R, Klibanski A. Hormone predictors of abnormal bone microarchitecture in women with anorexia nervosa. Bone. 2010 Feb; 46(2):458-63. PMID: 19747572; PMCID: PMC2818221.
  44. Lawson EA, Zhang X, Crocker JT, Wang WL, Klibanski A. Hypoglycemia from IGF2 overexpression associated with activation of fetal promoters and loss of imprinting in a metastatic hemangiopericytoma. J Clin Endocrinol Metab. 2009 Jul; 94(7):2226-31. PMID: 19383775.
    View in: PubMed
  45. Nachtigall LB, Valassi E, Lo J, McCarty D, Passeri J, Biller BM, Miller KK, Utz A, Grinspoon S, Lawson EA, Klibanski A. Gender effects on cardiac valvular function in hyperprolactinaemic patients receiving cabergoline: a retrospective study. Clin Endocrinol (Oxf). 2010 Jan; 72(1):53-8. PMID: 19508591.
    View in: PubMed
  46. Lawson EA, Misra M, Meenaghan E, Rosenblum L, Donoho DA, Herzog D, Klibanski A, Miller KK. Adrenal glucocorticoid and androgen precursor dissociation in anorexia nervosa. J Clin Endocrinol Metab. 2009 Apr; 94(4):1367-71. PMID: 19158192; PMCID: PMC2682472.
  47. Lawson EA, Buchbinder BR, Daniels GH. Hypopituitarism associated with a giant aneurysm of the internal carotid artery. J Clin Endocrinol Metab. 2008 Dec; 93(12):4616. PMID: 19056841.
    View in: PubMed
  48. Lawson EA, Klibanski A. Endocrine abnormalities in anorexia nervosa. Nat Clin Pract Endocrinol Metab. 2008 Jul; 4(7):407-14. PMID: 18542109.
    View in: PubMed
  49. Utz AL, Lawson EA, Misra M, Mickley D, Gleysteen S, Herzog DB, Klibanski A, Miller KK. Peptide YY (PYY) levels and bone mineral density (BMD) in women with anorexia nervosa. Bone. 2008 Jul; 43(1):135-9. PMID: 18486583; PMCID: PMC2493518.
  50. Miller KK, Wexler TL, Zha AM, Lawson EA, Meenaghan EM, Misra M, Binstock AB, Herzog DB, Klibanski A. Androgen deficiency: association with increased anxiety and depression symptom severity in anorexia nervosa. J Clin Psychiatry. 2007 Jun; 68(6):959-65. PMID: 17592924.
    View in: PubMed
  51. Lawson EA, Miller KK, Mathur VA, Misra M, Meenaghan E, Herzog DB, Klibanski A. Hormonal and nutritional effects on cardiovascular risk markers in young women. J Clin Endocrinol Metab. 2007 Aug; 92(8):3089-94. PMID: 17519306; PMCID: PMC3211045.
  52. Miller KK, Lawson EA, Mathur V, Wexler TL, Meenaghan E, Misra M, Herzog DB, Klibanski A. Androgens in women with anorexia nervosa and normal-weight women with hypothalamic amenorrhea. J Clin Endocrinol Metab. 2007 Apr; 92(4):1334-9. PMID: 17284620; PMCID: PMC3206093.
  53. Miller KK, Lee EE, Lawson EA, Misra M, Minihan J, Grinspoon SK, Gleysteen S, Mickley D, Herzog D, Klibanski A. Determinants of skeletal loss and recovery in anorexia nervosa. J Clin Endocrinol Metab. 2006 Aug; 91(8):2931-7. PMID: 16735492; PMCID: PMC3220933.
  54. Gaillard AW, Lawson EA. Evoked potentials to consonant-vowel syllables in a memory scanning task. Ann N Y Acad Sci. 1984; 425:204-9. PMID: 6588831.
    View in: PubMed
  55. Ebong WW, Lawson EA. Pattern of osteoarthritis of the hip in Nigerians. East Afr Med J. 1978 Feb; 55(2):81-4. PMID: 668609.
    View in: PubMed
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