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profileGeoffrey Young, M.D.

TitleAssistant Professor of Radiology
InstitutionBrigham and Women's Hospital
DepartmentRadiology
AddressBrigham and Women's Hospital
Radiology
75 Francis St
Boston MA 02115
Phone617/732-7260
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01LM012434     (XU, XIAOYIN)Sep 6, 2016 - Aug 31, 2021
NIH
Computer aided diagnosis of cancer metastases in the brain
Role: Principle Investigator (Two PI Mechanism)

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Nawfel RD, Young GS. Measured Head CT/CTA Skin Dose and Intensive Care Unit Patient Cumulative Exposure. AJNR Am J Neuroradiol. 2017 Mar; 38(3):455-461. PMID: 28104641.
    View in: PubMed
  2. Qin L, Li X, Stroiney A, Qu J, Helgager J, Reardon DA, Young GS. Advanced MRI assessment to predict benefit of anti-programmed cell death 1 protein immunotherapy response in patients with recurrent glioblastoma. Neuroradiology. 2017 Feb; 59(2):135-145. PMID: 28070598.
    View in: PubMed
  3. Qu JR, Young GS. Handbook of Neuro-Oncology Neuroimaging, Newton HB ed. Advanced MR Imaging of Brain Tumor. 2016; 167-81.
  4. Qu J, Qin L, Cheng S, Leung K, Li X, Li H, Dai J, Jiang T, Akgoz A, Seethamraju R, Wang Q, Rahman R, Li S, Ai L, Jiang T, Young GS. Residual low ADC and high FA at the resection margin correlate with poor chemoradiation response and overall survival in high-grade glioma patients. Eur J Radiol. 2016 Mar; 85(3):657-64. PMID: 26860681.
    View in: PubMed
  5. Abd-El-Barr MM, Santos SM, Aglio LS, Young GS, Mukundan S, Golby AJ, Gormley WB, Dunn IF. "Extraoperative" MRI (eoMRI) for Brain Tumor Surgery: Initial Results at a Single Institution. World Neurosurg. 2015 Jun; 83(6):921-8. PMID: 25700968; PMCID: PMC4469472.
  6. Himes N, Young GS. Image-Guided Neurosurgery, Golby AJ ed. Background on Imaging, Structural Imaging. 2015; 23-61.
  7. Akgoz A, Rahman R, You H, Qu J, Hamdan A, Seethamraju RT, Wen PY, Young GS. Spin-echo echo-planar perfusion prior to chemoradiation is a strong independent predictor of progression-free and overall survival in newly diagnosed glioblastoma. J Neurooncol. 2014 Aug; 119(1):111-9. PMID: 24792644.
    View in: PubMed
  8. Saar BG, Freudiger CW, Xu X, Huttner A, Kesari S, Young G, Xie XS. Coherent Raman tissue imaging in the brain. Cold Spring Harb Protoc. 2014 May 01; 2014(5). PMID: 24786507.
    View in: PubMed
  9. Ji M, Orringer DA, Freudiger CW, Ramkissoon S, Liu X, Lau D, Golby AJ, Norton I, Hayashi M, Agar NY, Young GS, Spino C, Santagata S, Camelo-Piragua S, Ligon KL, Sagher O, Xie XS. Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy. Sci Transl Med. 2013 Sep 04; 5(201):201ra119. PMID: 24005159; PMCID: PMC3806096.
  10. Hochberg AR, Young GS. Cerebral perfusion imaging. Semin Neurol. 2012 Sep; 32(4):454-65. PMID: 23361488.
    View in: PubMed
  11. Freudiger CW, Pfannl R, Orringer DA, Saar BG, Ji M, Zeng Q, Ottoboni L, Wei Y, Ying W, Waeber C, Sims JR, De Jager PL, Sagher O, Philbert MA, Xu X, Kesari S, Xie XS, Young GS. Multicolored stain-free histopathology with coherent Raman imaging. Lab Invest. 2012 Oct; 92(10):1492-502. PMID: 22906986; PMCID: PMC3622202.
  12. Zhu Y, Young GS, Xue Z, Huang RY, You H, Setayesh K, Hatabu H, Cao F, Wong ST. Semi-automatic segmentation software for quantitative clinical brain glioblastoma evaluation. Acad Radiol. 2012 Aug; 19(8):977-85. PMID: 22591720; PMCID: PMC3515056.
  13. Pope WB, Qiao XJ, Kim HJ, Lai A, Nghiemphu P, Xue X, Ellingson BM, Schiff D, Aregawi D, Cha S, Puduvalli VK, Wu J, Yung WK, Young GS, Vredenburgh J, Barboriak D, Abrey LE, Mikkelsen T, Jain R, Paleologos NA, Rn PL, Prados M, Goldin J, Wen PY, Cloughesy T. Apparent diffusion coefficient histogram analysis stratifies progression-free and overall survival in patients with recurrent GBM treated with bevacizumab: a multi-center study. J Neurooncol. 2012 Jul; 108(3):491-8. PMID: 22426926; PMCID: PMC3997502.
  14. Bergmark RW, Guo DP, Lin HW, Faquin WC, Young GS, Saxon KG. Vagal schwannoma. Ear Nose Throat J. 2011 Sep; 90(9):410-1. PMID: 21938697.
    View in: PubMed
  15. Chen X, Dai J, Ai L, Ru X, Wang J, Li S, Young GS. Clival invasion on multi-detector CT in 390 pituitary macroadenomas: correlation with sex, subtype and rates of operative complication and recurrence. AJNR Am J Neuroradiol. 2011 Apr; 32(4):785-9. PMID: 21436342.
    View in: PubMed
  16. Hu X, Wong KK, Young GS, Guo L, Wong ST. Support vector machine multiparametric MRI identification of pseudoprogression from tumor recurrence in patients with resected glioblastoma. J Magn Reson Imaging. 2011 Feb; 33(2):296-305. PMID: 21274970; PMCID: PMC3273302.
  17. Wong K, Young GS, Makale M, Hu X, Yildirim N, Cui K, Wong ST, Kesari S. Characterization of a human tumorsphere glioma orthotopic model using magnetic resonance imaging. J Neurooncol. 2011 Sep; 104(2):473-81. PMID: 21240539; PMCID: PMC3161186.
  18. Young GS. NEJM Journal Watch Neurology. Evidence Catching up to Evolving Practice in Stroke Imaging. A brief review and comment on the Schellinger et al. American Heart Association 2009 scientific statement of recommendations for imaging of acute ischemic stroke. 2011; 2(13):11.
  19. Young GS, Macklin EA, Setayesh K, Lawson JD, Wen PY, Norden AD, Drappatz J, Kesari S. Longitudinal MRI evidence for decreased survival among periventricular glioblastoma. J Neurooncol. 2011 Aug; 104(1):261-9. PMID: 21132516; PMCID: PMC3151407.
  20. Peters JM, Maclean AV, Young GS. Rapid resolution of diffusion weighted MRI abnormality in a patient with a stuttering stroke. BMJ Case Rep. 2010; 2010. PMID: 22315635; PMCID: PMC3027891.
  21. Drappatz J, Norden AD, Wong ET, Doherty LM, Lafrankie DC, Ciampa A, Kesari S, Sceppa C, Gerard M, Phan P, Schiff D, Batchelor TT, Ligon KL, Young G, Muzikansky A, Weiss SE, Wen PY. Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma. Int J Radiat Oncol Biol Phys. 2010 Sep 01; 78(1):85-90. PMID: 20137866.
    View in: PubMed
  22. Young GS, Stauss J, Mukundan S. Neuro-Oncology – A volume in the Blue Books of Neurology Series. Eds. Rees J and Wen P. Advanced Physiologic Imaging of Adult Brain Tumor. 2010; 71-98.
  23. Xian J, Xu Q, Wang Z, Yang B, Wei W, Yan Z, Sun J, Shi J, Young GS. MR imaging of adenomas of the nonpigmented ciliary epithelium of the eye. AJNR Am J Neuroradiol. 2010 May; 31(5):886-90. PMID: 20044507.
    View in: PubMed
  24. Young GS, Feng F, Shen H, Chen NK. Susceptibility-enhanced 3-Tesla T1-weighted spoiled gradient echo of the midbrain nuclei for guidance of deep brain stimulation implantation. Neurosurgery. 2009 Oct; 65(4):809-15. PMID: 19834387.
    View in: PubMed
  25. Kwong KK, Kloetzer L, Wong KK, Ren JQ, Kuo B, Jiang Y, Chen YI, Chan ST, Young GS, Wong ST. Bioluminescence imaging of heme oxygenase-1 upregulation in the Gua Sha procedure. J Vis Exp. 2009 Aug 28; (30). PMID: 19718012; PMCID: PMC3149908.
  26. Nie J, Xue Z, Liu T, Young GS, Setayesh K, Guo L, Wong ST. Automated brain tumor segmentation using spatial accuracy-weighted hidden Markov Random Field. Comput Med Imaging Graph. 2009 Sep; 33(6):431-41. PMID: 19446435; PMCID: PMC2739047.
  27. Wong KK, Tam CP, Ng M, Wong ST, Young GS. Improved residue function and reduced flow dependence in MR perfusion using least-absolute-deviation regularization. Magn Reson Med. 2009 Feb; 61(2):418-28. PMID: 19161133.
    View in: PubMed
  28. Young GS, Setayesh K. Spin-echo echo-planar perfusion MR imaging in the differential diagnosis of solitary enhancing brain lesions: distinguishing solitary metastases from primary glioma. AJNR Am J Neuroradiol. 2009 Mar; 30(3):575-7. PMID: 19095787.
    View in: PubMed
  29. Rojas C, Solari L, Herrera C, Sanchez E, Young G, Bonilla C, Hurtado R, Muñoz M, Zeladita J, Espiritu B, Shin S. Challenges of diagnosis and management of tuberculosis and HIV coinfection in resource-limited settings: a case report from Lima, Peru. J Int Assoc Physicians AIDS Care (Chic). 2008 Sep-Oct; 7(5):232-7. PMID: 18812592.
    View in: PubMed
  30. Rojas C, Solary L, Sanchez E, Herrera C, Young G, Hurtado R, Muñoz M, Zeladita J, Espiritu B, Shin S . Challenges of Diagnosis and Management of TB and HIV Co-Infection in Resource-Limited Settings: A Case Report from Lima, Peru. Journal of the International Association of Physicians in AIDS Care (JIAPAC). 2008; 5(7):232-7.
  31. Wong KK, Tam CP, Ng M, Wong STC, Young GS. Improved Residue Function and Reduced Flow Dependence in MR Perfusion Using Least-Absolute-Deviation Regularization. Magnetic Resonance Medicine. 2008; 2(61):418-28.
  32. Young GS*, Setayesh K (*Senior and corresponding author). Spin-Echo EPI Perfusion MRI in Differential Diagnosis of Solitary Enhancing Brain Lesions: Distinguishing Solitary Metastasis from Primary Glioma. American Journal of Neuroradiology. 2008; 3(30):575-7.
  33. Chen NK, Young GS. Improvement of Midbrain Susceptibility Contrast in T1-Weighted SPGR for Image Guided Deep Brain Stimulation. Proceedings of ISMRM 2008 #3515. 2008.
  34. Wong K, Tam CP, Ng M, Wong STC, Young GS. Improved Deconvolution of Residue Function in MR Perfusion in the Presence of Bolus Delay and Dispersion Using Least-Absolute-Deviation Regularization. Proceedings of ISMRM 2008 #1901. 2008.
  35. Liu T, Chu WC, Young G, Li K, Yeung BH, Guo L, Man GC, Lam WW, Wong ST, Cheng JC. MR analysis of regional brain volume in adolescent idiopathic scoliosis: neurological manifestation of a systemic disease. J Magn Reson Imaging. 2008 Apr; 27(4):732-6. PMID: 18302230; PMCID: PMC2430659.
  36. Norden AD, Young GS, Setayesh K, Muzikansky A, Klufas R, Ross GL, Ciampa AS, Ebbeling LG, Levy B, Drappatz J, Kesari S, Wen PY. Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence. Neurology. 2008 Mar 04; 70(10):779-87. PMID: 18316689.
    View in: PubMed
  37. Nie J, Liu T, Li G, Young G, Tarokh A, Guo L, Wong ST. Least-square conformal brain mapping with spring energy. Comput Med Imaging Graph. 2007 Dec; 31(8):656-64. PMID: 17950575; PMCID: PMC2692312.
  38. Young GS. Advanced MRI of adult brain tumors. Neurol Clin. 2007 Nov; 25(4):947-73, viii. PMID: 17964022.
    View in: PubMed
  39. Evans CL, Xu X, Kesari S, Xie XS, Wong ST, Young GS. Chemically-selective imaging of brain structures with CARS microscopy. Opt Express. 2007 Sep 17; 15(19):12076-87. PMID: 19547572.
    View in: PubMed
  40. Liu T, Chu WCW, Young GS, Li K, Yeung BHY, Guo L, Man GCW, Lam WMW, Wong STC, Cheng JCY. Neuroanatomic asymmetries in regions of the brain functionally related to somatic motor control and coordination in AIS subjects: Regional brain volume analysis with volumetric MR imaging. Scoliosis Research Society 42nd Annual Meeting Program. 2007.
  41. Liu T, Chu WCW, Young GS, Li K, Yeung BHY, Guo L, Man GCW, Lam WWM, Wong STC, Cheng JY . MR analysis of Regional Brain Volume in Adolescent Idiopathic Scoliosis – neurological manifestation of a systemic disease. Journal of Magnetic Resonance Imaging (JMRI). 2007; 4(27):732-6.
  42. Young GS, Chen NK. RUST SWI - High Contrast SWI for Midbrain Parenchymal Contrast. Proceedings of ISMRM 2007 #937. 2007; 937.
  43. Wong K, Young GS. Longitudinal Study of Cerebral Vasculitis Using Functional Diffusion Mapping. Program of the American Society of Neuroradiology, Vancouver BC, Canada. 2007; May.
  44. Monje ML, Ramakrishna NR, Young G, Drappatz J, Doherty LM, Wen PY, Kesari S. Durable response of a radiation-induced, high-grade cerebellar glioma to temozolomide. J Neurooncol. 2007 Sep; 84(2):179-83. PMID: 17332945.
    View in: PubMed
  45. Nie JX, Liu TM, Li G, Young GS, Tarokh A, Guo L, Wong STC . Least-Square Conformal Brain Mapping with Spring Energy. Computerized Medical Imaging and Graphics. 2007; In Press.
  46. Geoffrey S. Young. Neurology Board Review: Neuroimaging. 2007.
  47. Zhang Y, Young G, Zhou X, Srinivasan R, Wong STC . Cerebral Arteries Extraction using Level Set Segmentation and Adaptive Tracing for CT Angiography. Proceedings of the 2007 International Symposium on Computational Models for Life Sciences - CMLS'07. 2007; Accepted.
  48. Geoffrey S. Young, Shuang Xia. Advanced MR Imaging of Brain Tumor. Handbook of Neuro-Oncology Neuro-Imaging, Eds. Herbert Newton and Ferenc Jolesz. 2007; 136-149.
  49. Young GS, Xia S. Handbook of Neuro-Oncology Neuro-Imaging, Eds. Herbert Newton and Ferenc Jolesz. Advanced MR Imaging of Brain Tumor. 2007; 136-49.
  50. *Lin YR,*Young GS, Chen NK, Dillon WP, Wong S (*Senior and corresponding author) . CJD involvement of Rolandic Cortex: A Quantitative ADC Evaluation. American Journal of Neuroradiology. 2006; 27(8):1755-9.
  51. Gorniak RJ, Young GS, Wiese DE, Marty FM, Schwartz RB. MR imaging of human herpesvirus-6-associated encephalitis in 4 patients with anterograde amnesia after allogeneic hematopoietic stem-cell transplantation. AJNR Am J Neuroradiol. 2006 Apr; 27(4):887-91. PMID: 16611785.
    View in: PubMed
  52. Liu T, Young G, Huang L, Chen NK, Wong ST. 76-space analysis of grey matter diffusivity: methods and applications. Neuroimage. 2006 May 15; 31(1):51-65. PMID: 16434215.
    View in: PubMed
  53. Young GS, Lin YR, Chen NK, Dillon WP, Wong S . Abnormality of Apparent Diffusion Coefficient (ADC) in Somatosensory Cortex in Jakob-Creutzfeld disease (CJD): Is Rolandic Cortex Really Spared?. Radiologic Society of North America (RSNA) Program, 91st Annual Meeting, Chicago IL. 2005; Nov.
  54. Liu TM, Young GS, Ling H, Chen NK, Dillon WP, Wong S. 76-space Analysis of Grey Matter Diffusivity of Creutzfeldt-Jakob Disease. Radiologic Society of North America (RSNA) Program, 91st Annual Meeting, Chicago IL. 2005.
  55. Liu T, Young G, Huang L, Chen NK, Wong ST. 76-space analysis of grey matter diffusivity: methods and applications. Med Image Comput Comput Assist Interv. 2005; 8(Pt 1):148-55. PMID: 16685840.
    View in: PubMed
  56. Young GS, Geschwind MD, Dillon WP, Henry RG, Martindale JL, Wong S, Liu H, Lu Y, Fischbein N, Miller BL. Diffusion Weighted Imaging (DWI) and FLAIR in Creutzfeldt-Jakob disease (CJD). American Journal of Neuroradiology. 2005; 26 (Jun-Jul (6)):1551-62.
  57. Ma QY, Chan KC, Kacher DF, Gao E, Chow MS, Wong KK, Xu H, Yang ES, Young GS, Miller JR, Jolesz FA. Superconducting RF coils for clinical MR imaging at low field. Acad Radiol. 2003 Sep; 10(9):978-87. PMID: 13678086.
    View in: PubMed
  58. Martindale J, Geschwind MD, De Armond S, Young G, Dillon WP, Henry R, Uyehara-Lock JH, Gaskin DA, Miller BL. Sporadic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease. Arch Neurol. 2003 May; 60(5):767-70. PMID: 12756143.
    View in: PubMed
  59. von Koch CS, Young G, Chin CT, Lawton MT. Magnetic resonance imaging/spectroscopy of an intraaxial epidermoid: similarity to an abscess. Case illustration. J Neurosurg. 2002 Aug; 97(2):492. PMID: 12186484.
    View in: PubMed
  60. Young GS, Lai A, Majumdar S, Maier SE, Dillon WP, Chin CT. MR Line Scan Diffusion Imaging of the Spine in Normal Adult and Pediatric Patients. . Program of the American Society of Neuroradiology, Vancouver BC, Canada. 2002; May.
  61. Soo Hoo K, Wong STC, Knowlton RC, Young GS, Walker J, Cao X, Dillon WP, Hawkins RA, Laxer KD. A Brain Imaging Registry for Neurologic Diagnosis and Research . Proceedings, Society of Photo-Optical Instrumentation Engineers (SPIE) Medical Imaging 2002, San Diego CA. 2002; February.
  62. Chin CT, Young GS, Lai A, Majumdar S, Maier SE, Dillon WP . Correlation of MR Line Scan Diffusion Imaging with Conventional MR Imaging of the Spine. Program of the American Society of Neuroradiology, Vancouver BC, Canada. 2002; May.
  63. Gao E, Chan KC, Chow MS, Wong KK, Yan B, Fang J, Jolesz FA, Kacher DK, Ma DK, Young G, Yang ES. Superconducting MR Helmholtz Coil Pair for Human Imaging with Improved Penetration. International Society of Magnetic Resonance Medicine Program. 2001; April.
  64. Kacher DF, Gao E, O’Leary HM, Kyriakos WE, Kaufhold JP, Young GS, Ma QY, Wells WM, Jolesz FA. RF Coil Sensitivity Estimation for Intensity Correction or Encoding. International Society of Magnetic Resonance Medicine Program. 2000; April.
  65. Ma QY, Gao E, Miller JR, Xu X, Chan KC, Wong KK, Yang ES, Kacher DF, Young GS, Jolesz FA, Face DW, Kountz DJ . Superconducting MR Surface Coils for Human Imaging. International Society of Magnetic Resonance Medicine Proceedings. 1999.
  66. Ma QY, Gao E, Xu H, Kacher DF, Young GS, Jolesz FA, Chan E, Wong K, Yang ES. Superconducting RF Coils for Human Magnetic Resonance Imaging. Proceedings, American Physical Society Centennial Meeting, Atlanta GA, March 1999 . 1999; March.
  67. Young GS, Silverman SG, Kettenbach J, Hata N, Golland P, Jolesz FA, Loughlin KR, Kinkinis R. Three-Dimensional CT for Planning Urologic Surgery. Urologic Clinics of North America. 1998; February(25:1).
  68. Kaufmann CA, Young GS, Malaspina D, Monto A, Speer M, Ott J, Bruder G, Chan S, Whitaker A, Strauss DH, Latov, Gorman J. Etiologic, Pathophysiologic, Symptomatic, Therapeutic, and Prognostic Correlates of Familiality in Schizophrenia. Schizophrenia Research. 1993; 9:119.
  69. Kaufmann CA, Monto A, Young GS, Malaspina D, Speer M, Mrette C, Ottman, Ott J . Does Early Onset Characterize Autosomal Dominant Schizophrenia?. Schizophrenia Research. 1993; 9:118.
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