Harvard Catalyst Profiles

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Varun Kumar, Ph.D.


Kent State University, Kent, Ohio, USAPhD05/2016Neuroscience
Stanford University, Stanford, CA, USAPostdoc08/2018Ophthalmology/ Neuro-Ophthalmology
Harvard University, Boston, MA, USAPostdoc03/2020Ophthalmology
Harvard University, Boston, MA, USAResearch Investigator/InstructorOphthalmology
All India Combined Biotechnology Entrance Exam, India (All India Rank 255)
Junior Research Fellowship (JRF) for Ph.D., India (All India Rank 147)
Graduate Aptitude Test in Engineering (GATE), India (All India Rank 161)
Shortlisted for Commonwealth Scholarship UK, Korean Government scholarship, Korea
Best Doctoral Poster Presentation, Kent State University, Ohio, USA
Research grant award, Kent State University, Ohio, USA
Postdoctoral Research Fellowship, American Heart Association, USA
ARVO Travel Award
2020 - 2022
K99/ R00 (NIH/NEI Pathway to Independence) (Principal Investigator)
2021 - 2022
Eversight Research Grant (Co-Investigator)
Santel, Inc./ ARVO Travel award

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. Eversight Research Grant (Ula V Jurkunas (PI)) Jan 1, 2021 - Jan 1, 2022
    Role of estrogen metabolizing enzyme in mitophagy for Fuchs endothelial corneal dystrophy
    Role: Co-Investigator
  2. K99EY031339 (KUMAR, VARUN) May 1, 2020 - Apr 30, 2022
    Understanding Endoplasmic Reticulum-Mitochondrial Cross-Talk in Corneal Endothelial Cells
    Role: Principal Investigator
  3. 18POST34030385 (Varun Kumar) Jul 1, 2018 - Jul 1, 2020
    American Heart Association Postdoctoral Fellowship
    Glia ER stress in Pathophysiology and Treatment of Diabetes and Ischemic optic Neuropathy.
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kumar V, Jurkunas UV. Mitochondrial Dysfunction and Mitophagy in Fuchs Endothelial Corneal Dystrophy. Cells. 2021 Jul 26; 10(8). PMID: 34440658.
    Citations:    Fields:    
  2. White TL, Deshpande N, Kumar V, Gauthier AG, Jurkunas UV. Cell cycle re-entry and arrest in G2/M phase induces senescence and fibrosis in Fuchs Endothelial Corneal Dystrophy. Free Radic Biol Med. 2021 02 20; 164:34-43. PMID: 33418109.
    Citations:    Fields:    Translation:HumansCells
  3. Kumar V, Ali Shariati M, Mesentier-Louro L, Jinsook Oh A, Russano K, Goldberg JL, Liao YJ. Dual Specific Phosphatase 14 Deletion Rescues Retinal Ganglion Cells and Optic Nerve Axons after Experimental Anterior Ischemic Optic Neuropathy. Curr Eye Res. 2021 05; 46(5):710-718. PMID: 33107352.
    Citations:    Fields:    
  4. Mesentier-Louro LA, Shariati MA, Dalal R, Camargo A, Kumar V, Shamskhou EA, de Jesus Perez V, Liao YJ. Systemic hypoxia led to little retinal neuronal loss and dramatic optic nerve glial response. Exp Eye Res. 2020 04; 193:107957. PMID: 32032627.
    Citations: 3     Fields:    Translation:AnimalsCells
  5. Liu C, Miyajima T, Melangath G, Miyai T, Vasanth S, Deshpande N, Kumar V, Ong Tone S, Gupta R, Zhu S, Vojnovic D, Chen Y, Rogan EG, Mondal B, Zahid M, Jurkunas UV. Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):573-583. PMID: 31852820.
    Citations: 12     Fields:    Translation:HumansAnimals
  6. Miyajima T, Melangath G, Zhu S, Deshpande N, Vasanth S, Mondal B, Kumar V, Chen Y, Price MO, Price FW, Rogan EG, Zahid M, Jurkunas UV. Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy. Free Radic Biol Med. 2020 02 01; 147:69-79. PMID: 31857234.
    Citations: 6     Fields:    Translation:HumansCells
  7. Kumar V. Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases. Neurology (ECronicon). 2019 Sep; 11(9):864-873. PMID: 31528859.
    Citations: 1     
  8. Miyai T, Vasanth S, Melangath G, Deshpande N, Kumar V, Benischke AS, Chen Y, Price MO, Price FW, Jurkunas UV. Activation of PINK1-Parkin-Mediated Mitophagy Degrades Mitochondrial Quality Control Proteins in Fuchs Endothelial Corneal Dystrophy. Am J Pathol. 2019 10; 189(10):2061-2076. PMID: 31361992.
    Citations: 12     Fields:    Translation:HumansCells
  9. Kumar V, Mesentier-Louro LA, Oh AJ, Heng K, Shariati MA, Huang H, Hu Y, Liao YJ. Increased ER Stress After Experimental Ischemic Optic Neuropathy and Improved RGC and Oligodendrocyte Survival After Treatment With Chemical Chaperon. Invest Ophthalmol Vis Sci. 2019 05 01; 60(6):1953-1966. PMID: 31060051.
    Citations: 6     Fields:    Translation:AnimalsCells
  10. Kumar V, Weng YC, Wu YC, Huang YT, Liu TH, Kristian T, Liu YL, Tsou HH, Chou WH. Genetic inhibition of PKCe attenuates neurodegeneration after global cerebral ischemia in male mice. J Neurosci Res. 2019 04; 97(4):444-455. PMID: 30488977.
    Citations: 2     Fields:    Translation:AnimalsCells
  11. Kumar V, Weng YC, Wu YC, Huang YT, Chou WH. PKCe phosphorylation regulates the mitochondrial translocation of ATF2 in ischemia-induced neurodegeneration. BMC Neurosci. 2018 Nov 29; 19(1):76. PMID: 30497386.
    Citations: 3     Fields:    Translation:AnimalsCells
  12. Ali Shariati M, Kumar V, Yang T, Chakraborty C, Barres BA, Longo FM, Liao YJ. A Small Molecule TrkB Neurotrophin Receptor Partial Agonist as Possible Treatment for Experimental Nonarteritic Anterior Ischemic Optic Neuropathy. Curr Eye Res. 2018 12; 43(12):1489-1499. PMID: 30273053.
    Citations: 3     Fields:    Translation:AnimalsCells
  13. Kumar V. Eye is the Window to the Brain Pathology. Curr Adv Ophthalmol. 2018 Aug; 1(1):3-4. PMID: 31123726.
    Citations: 1     
  14. Kumar V. Understanding Retinal Changes after Stroke. Open J Ophthalmol. 2017 Nov; 7(4):281-292. PMID: 30956896.
  15. Chou WH, Wang G, Kumar V, Weng YC. Lipocalin-2 in Stroke. Neuro. 2015 Aug; 2(1):38-41. PMID: 30542675.
    Citations: 1     
  16. Kumar V, Weng YC, Geldenhuys WJ, Wang D, Han X, Messing RO, Chou WH. Generation and characterization of ATP analog-specific protein kinase Cd. J Biol Chem. 2015 Jan 23; 290(4):1936-51. PMID: 25505183.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.