Harvard Catalyst Profiles

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Adam Flaczyk, M.B.,B.S.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lin YJ, Flaczyk A, Wolfheimer S, Goretzki A, Jamin A, Wangorsch A, Vieths S, Scheurer S, Schülke S. The Fusion Protein rFlaA:Betv1 Modulates DC Responses by a p38-MAPK and COX2-Dependent Secretion of PGE2 from Epithelial Cells. Cells. 2021 12 04; 10(12). PMID: 34943923.
    Citations: 3     Fields:    Translation:AnimalsCells
  2. Rhee J, Kuznetsov A, McKay T, Lyons M, Houstis N, Mekkonen J, Ethridge B, Ibala R, Hahm E, Gitlin J, Guseh JS, Kitchen R, Rosenzweig A, Shaefi S, Flaczyk A, Qu J, Akeju O. Serum Proteomics of Older Patients Undergoing Major Cardiac Surgery: Identification of Biomarkers Associated With Postoperative Delirium. Front Aging Neurosci. 2021; 13:699763. PMID: 34456709; PMCID: PMC8386117.
  3. Flaczyk A, Rosovsky RP, Reed CT, Bankhead-Kendall BK, Bittner EA, Chang MG. Comparison of published guidelines for management of coagulopathy and thrombosis in critically ill patients with COVID 19: implications for clinical practice and future investigations. Crit Care. 2020 09 16; 24(1):559. PMID: 32938471.
    Citations: 37     Fields:    Translation:HumansCellsPHPublic Health
  4. Xu J, Eastman AJ, Flaczyk A, Neal LM, Zhao G, Carolan J, Malachowski AN, Stolberg VR, Yosri M, Chensue SW, Curtis JL, Osterholzer JJ, Olszewski MA. Erratum for Xu et al., "Disruption of Early Tumor Necrosis Factor Alpha Signaling Prevents Classical Activation of Dendritic Cells in Lung-Associated Lymph Nodes and Development of Protective Immunity against Cryptococcal Infection". mBio. 2018 05 29; 9(3). PMID: 29844115.
    Citations:    Fields:    
  5. Laiño J, Wangorsch A, Blanco F, Wolfheimer S, Krause M, Flaczyk A, Möller TM, Tsai M, Galli S, Vieths S, Toda M, Scheurer S, Schülke S. Targeting of Immune Cells by Dual TLR2/7 Ligands Suppresses Features of Allergic Th2 Immune Responses in Mice. J Immunol Res. 2017; 2017:7983217. PMID: 29204451; PMCID: PMC5674512.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  6. Xu J, Flaczyk A, Neal LM, Fa Z, Cheng D, Ivey M, Moore BB, Curtis JL, Osterholzer JJ, Olszewski MA. Exploitation of Scavenger Receptor, Macrophage Receptor with Collagenous Structure, by Cryptococcus neoformans Promotes Alternative Activation of Pulmonary Lymph Node CD11b+ Conventional Dendritic Cells and Non-Protective Th2 Bias. Front Immunol. 2017; 8:1231. PMID: 29033946.
    Citations: 6     Fields:    
  7. Schülke S, Fiedler AH, Junker AC, Flaczyk A, Wolfheimer S, Wangorsch A, Heinz A, Beckert H, Nagl B, Bohle B, Vieths S, Toda M, Scheurer S. Critical role of mammalian target of rapamycin for IL-10 dendritic cell induction by a flagellin A conjugate in preventing allergic sensitization. J Allergy Clin Immunol. 2018 05; 141(5):1786-1798.e11. PMID: 28886863.
    Citations: 13     Fields:    Translation:AnimalsCells
  8. Xu J, Flaczyk A, Neal LM, Fa Z, Eastman AJ, Malachowski AN, Cheng D, Moore BB, Curtis JL, Osterholzer JJ, Olszewski MA. Scavenger Receptor MARCO Orchestrates Early Defenses and Contributes to Fungal Containment during Cryptococcal Infection. J Immunol. 2017 05 01; 198(9):3548-3557. PMID: 28298522; PMCID: PMC5423401.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  9. Xu J, Eastman AJ, Flaczyk A, Neal LM, Zhao G, Carolan J, Malachowski AN, Stolberg VR, Yosri M, Chensue SW, Curtis JL, Osterholzer JJ, Olszewski MA. Disruption of Early Tumor Necrosis Factor Alpha Signaling Prevents Classical Activation of Dendritic Cells in Lung-Associated Lymph Nodes and Development of Protective Immunity against Cryptococcal Infection. mBio. 2016 07 12; 7(4). PMID: 27406560.
    Citations: 19     Fields:    Translation:AnimalsCells
  10. Schülke S, Vogel L, Junker AC, Hanschmann KM, Flaczyk A, Vieths S, Scheurer S. A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro. J Immunol Res. 2016; 2016:4156456. PMID: 27340679.
    Citations: 10     Fields:    Translation:HumansCells
  11. Shourian M, Flaczyk A, Angers I, Mindt BC, Fritz JH, Qureshi ST. The Cnes2 locus on mouse chromosome 17 regulates host defense against cryptococcal infection through pleiotropic effects on host immunity. Infect Immun. 2015 Dec; 83(12):4541-54. PMID: 26371125; PMCID: PMC4645399.
    Citations: 5     Fields:    Translation:AnimalsCells
  12. Schülke S, Flaczyk A, Vogel L, Gaudenzio N, Angers I, Löschner B, Wolfheimer S, Spreitzer I, Qureshi S, Tsai M, Galli S, Vieths S, Scheurer S. MPLA shows attenuated pro-inflammatory properties and diminished capacity to activate mast cells in comparison with LPS. Allergy. 2015 Oct; 70(10):1259-68. PMID: 26081583.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  13. Lafferty EI, Flaczyk A, Angers I, Homer R, d'Hennezel E, Malo D, Piccirillo CA, Vidal SM, Qureshi ST. An ENU-induced splicing mutation reveals a role for Unc93b1 in early immune cell activation following influenza A H1N1 infection. Genes Immun. 2014 Jul-Aug; 15(5):320-32. PMID: 24848930.
    Citations: 7     Fields:    Translation:AnimalsCells
  14. Flaczyk A, Duerr CU, Shourian M, Lafferty EI, Fritz JH, Qureshi ST. IL-33 signaling regulates innate and adaptive immunity to Cryptococcus neoformans. J Immunol. 2013 Sep 01; 191(5):2503-13. PMID: 23894196.
    Citations: 39     Fields:    Translation:AnimalsCells
  15. Carroll SF, Lafferty EI, Flaczyk A, Fujiwara TM, Homer R, Morgan K, Loredo-Osti JC, Qureshi ST. Susceptibility to progressive Cryptococcus neoformans pulmonary infection is regulated by loci on mouse chromosomes 1 and 9. Infect Immun. 2012 Dec; 80(12):4167-76. PMID: 22988020.
    Citations: 9     Fields:    Translation:AnimalsCells
  16. Kanagaratham C, Camateros P, Flaczyk A, Radzioch D. Polymorphisms in TOLL-like receptor genes and their roles in allergic asthma and atopy. Recent Pat Inflamm Allergy Drug Discov. 2011 Jan; 5(1):45-56. PMID: 21158736.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.