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Naama Kanarek, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Maynard AG, Kanarek N. NADH Ties One-Carbon Metabolism to Cellular Respiration. Cell Metab. 2020 Apr 07; 31(4):660-662. PMID: 32268110.
    Citations:    
  2. Kanarek N, Petrova B, Sabatini DM. Dietary modifications for enhanced cancer therapy. Nature. 2020 03; 579(7800):507-517. PMID: 32214253.
    Citations:    
  3. Kanarek N, Keys HR, Cantor JR, Lewis CA, Chan SH, Kunchok T, Abu-Remaileh M, Freinkman E, Schweitzer LD, Sabatini DM. Histidine catabolism is a major determinant of methotrexate sensitivity. Nature. 2018 07; 559(7715):632-636. PMID: 29995852.
    Citations:    
  4. Cantor JR, Abu-Remaileh M, Kanarek N, Freinkman E, Gao X, Louissaint A, Lewis CA, Sabatini DM. Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase. Cell. 2017 Apr 06; 169(2):258-272.e17. PMID: 28388410.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  5. Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, Sabatini DM. Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Cell. 2014 Aug 28; 158(5):1094-1109. PMID: 25171410.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  6. Horwitz E, Stein I, Andreozzi M, Nemeth J, Shoham A, Pappo O, Schweitzer N, Tornillo L, Kanarek N, Quagliata L, Zreik F, Porat RM, Finkelstein R, Reuter H, Koschny R, Ganten T, Mogler C, Shibolet O, Hess J, Breuhahn K, Grunewald M, Schirmacher P, Vogel A, Terracciano L, Angel P, Ben-Neriah Y, Pikarsky E. Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment. Cancer Discov. 2014 Jun; 4(6):730-43. PMID: 24687604.
    Citations:    
  7. Kanarek N, Grivennikov SI, Leshets M, Lasry A, Alkalay I, Horwitz E, Shaul YD, Stachler M, Voronov E, Apte RN, Pagano M, Pikarsky E, Karin M, Ghosh S, Ben-Neriah Y. Critical role for IL-1ß in DNA damage-induced mucositis. Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6):E702-11. PMID: 24469832.
    Citations: 8     Fields:    Translation:AnimalsCells
  8. Kanarek N, Ben-Neriah Y. Regulation of NF-?B by ubiquitination and degradation of the I?Bs. Immunol Rev. 2012 Mar; 246(1):77-94. PMID: 22435548.
    Citations:    
  9. Duan S, Skaar JR, Kuchay S, Toschi A, Kanarek N, Ben-Neriah Y, Pagano M. mTOR generates an auto-amplification loop by triggering the ßTrCP- and CK1a-dependent degradation of DEPTOR. Mol Cell. 2011 Oct 21; 44(2):317-24. PMID: 22017877.
    Citations:    
  10. Kanarek N, Horwitz E, Mayan I, Leshets M, Cojocaru G, Davis M, Tsuberi BZ, Pikarsky E, Pagano M, Ben-Neriah Y. Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCF{beta}-TrCP by single substrate depletion. Genes Dev. 2010 Mar 01; 24(5):470-7. PMID: 20194439.
    Citations:    
  11. Kanarek N, London N, Schueler-Furman O, Ben-Neriah Y. Ubiquitination and degradation of the inhibitors of NF-kappaB. Cold Spring Harb Perspect Biol. 2010 Feb; 2(2):a000166. PMID: 20182612.
    Citations:    
  12. Zach N, Kanarek N, Inbar D, Grinvald Y, Milestein T, Vaadia E. Segregation between acquisition and long-term memory in sensorimotor learning. Eur J Neurosci. 2005 Nov; 22(9):2357-62. PMID: 16262674.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.