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Brad Andrew Palanski, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Abadie V, Kim SM, Lejeune T, Palanski BA, Ernest JD, Tastet O, Voisine J, Discepolo V, Marietta EV, Hawash MBF, Ciszewski C, Bouziat R, Panigrahi K, Horwath I, Zurenski MA, Lawrence I, Dumaine A, Yotova V, Grenier JC, Murray JA, Khosla C, Barreiro LB, Jabri B. IL-15, gluten and HLA-DQ8 drive tissue destruction in coeliac disease. Nature. 2020 02; 578(7796):600-604. PMID: 32051586.
    Citations:    
  2. Sankaranarayanan K, Antaris XX, Palanski BA, El Gamal A, Kao CM, Fitch WL, Fischer CR, Khosla C. Tunable Enzymatic Synthesis of the Immunomodulator Lipid IVA To Enable Structure-Activity Analysis. J Am Chem Soc. 2019 06 19; 141(24):9474-9478. PMID: 31184877.
    Citations:    
  3. Melkonian AV, Weng N, Palanski BA, Khosla C. In Vivo Measurement of Redox-Regulated TG2 Activity. Methods Mol Biol. 2019; 1967:263-274. PMID: 31069776.
    Citations:    
  4. Plugis NM, Weng N, Zhao Q, Palanski BA, Maecker HT, Habtezion A, Khosla C. Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin. Proc Natl Acad Sci U S A. 2018 08 28; 115(35):8781-8786. PMID: 30104382.
    Citations:    
  5. Palanski BA, Khosla C. Cystamine and Disulfiram Inhibit Human Transglutaminase 2 via an Oxidative Mechanism. Biochemistry. 2018 06 19; 57(24):3359-3363. PMID: 29570977.
    Citations:    
  6. Shinde AV, Su Y, Palanski BA, Fujikura K, Garcia MJ, Frangogiannis NG. Pharmacologic inhibition of the enzymatic effects of tissue transglutaminase reduces cardiac fibrosis and attenuates cardiomyocyte hypertrophy following pressure overload. J Mol Cell Cardiol. 2018 04; 117:36-48. PMID: 29481819.
    Citations: 2     Fields:    
  7. Bouziat R, Hinterleitner R, Brown JJ, Stencel-Baerenwald JE, Ikizler M, Mayassi T, Meisel M, Kim SM, Discepolo V, Pruijssers AJ, Ernest JD, Iskarpatyoti JA, Costes LM, Lawrence I, Palanski BA, Varma M, Zurenski MA, Khomandiak S, McAllister N, Aravamudhan P, Boehme KW, Hu F, Samsom JN, Reinecker HC, Kupfer SS, Guandalini S, Semrad CE, Abadie V, Khosla C, Barreiro LB, Xavier RJ, Ng A, Dermody TS, Jabri B. Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease. Science. 2017 04 07; 356(6333):44-50. PMID: 28386004.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  8. Plugis NM, Palanski BA, Weng CH, Albertelli M, Khosla C. Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine: IMPLICATIONS FOR CELIAC DISEASE. J Biol Chem. 2017 02 03; 292(5):2000-2008. PMID: 28003361.
    Citations:    
  9. Guo S, Palanski BA, Kloeck C, Khosla C, Cui B. Intracellular TG2 Activity Increases Microtubule Stability but is not Sufficient to Prompt Neurite Growth. Neurosci Bull. 2017 Feb; 33(1):103-106. PMID: 27815680.
    Citations:    
  10. Yi MC, Palanski BA, Quintero SA, Plugis NM, Khosla C. An unprecedented dual antagonist and agonist of human Transglutaminase 2. Bioorg Med Chem Lett. 2015 Nov 01; 25(21):4922-4926. PMID: 26004580.
    Citations:    
  11. Alvarez-Sieiro P, Martin MC, Redruello B, Del Rio B, Ladero V, Palanski BA, Khosla C, Fernandez M, Alvarez MA. Generation of food-grade recombinant Lactobacillus casei delivering Myxococcus xanthus prolyl endopeptidase. Appl Microbiol Biotechnol. 2014 Aug; 98(15):6689-700. PMID: 24752841.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.