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Juan Carlos Ibla, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Emani S, Emani VS, Diallo FB, Diallo MA, Torres A, Nathan M, Ibla JC, Emani SM. Thromboelastography During Rewarming for Management of Pediatric Cardiac Surgery Patients. Ann Thorac Surg. 2021 Mar 02. PMID: 33667464.
    Citations:    Fields:    
  2. Katneni UK, Alexaki A, Hunt RC, Schiller T, DiCuccio M, Buehler PW, Ibla JC, Kimchi-Sarfaty C. Coagulopathy and Thrombosis as a Result of Severe COVID-19 Infection: A Microvascular Focus. Thromb Haemost. 2020 Dec; 120(12):1668-1679. PMID: 32838472.
    Citations: 5     Fields:    Translation:HumansAnimals
  3. Katneni UK, Holcomb DD, Hernandez NE, Hamasaki-Katagiri N, Hunt RC, Bar H, Ibla JC, Kimchi-Sarfaty C. In silico features of ADAMTS13 contributing to plasmatic ADAMTS13 levels in neonates with congenital heart disease. Thromb Res. 2020 09; 193:66-76. PMID: 32531546.
    Citations:    Fields:    
  4. Kames J, Alexaki A, Holcomb DD, Santana-Quintero LV, Athey JC, Hamasaki-Katagiri N, Katneni U, Golikov A, Ibla JC, Bar H, Kimchi-Sarfaty C. TissueCoCoPUTs: Novel Human Tissue-Specific Codon and Codon-Pair Usage Tables Based on Differential Tissue Gene Expression. J Mol Biol. 2020 05 15; 432(11):3369-3378. PMID: 31982380.
    Citations: 2     Fields:    Translation:Humans
  5. Choi PS, Emani S, Ibla JC, Marturano JE, Lowery TJ, Emani S. Magnetic Resonance-Based Diagnostics for Bleeding Assessment in Neonatal Cardiac Surgery. Ann Thorac Surg. 2020 06; 109(6):1931-1936. PMID: 31887277.
    Citations:    Fields:    Translation:Humans
  6. Matte GS, Howe RJ, Ibla J, Emani S, Emani SM. Transition from Hemochron Response to Hemochron Signature Elite Activated Clotting Time Devices in a Congenital Cardiac Surgery Practice. J Extra Corpor Technol. 2019 Dec; 51(4):221-226. PMID: 31915405.
    Citations:    Fields:    Translation:Humans
  7. Hunt R, Hettiarachchi G, Katneni U, Hernandez N, Holcomb D, Kames J, Alnifaidy R, Lin B, Hamasaki-Katagiri N, Wesley A, Kafri T, Morris C, Bouché L, Panico M, Schiller T, Ibla J, Bar H, Ismail A, Morris H, Komar A, Kimchi-Sarfaty C. A Single Synonymous Variant (c.354G>A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity. Int J Mol Sci. 2019 Nov 15; 20(22). PMID: 31731663.
    Citations: 2     Fields:    Translation:HumansCells
  8. Zuppa AF, Nicolson SC, Wilder NS, Ibla JC, Gottlieb EA, Burns KM, Stylianou M, Trachtenberg F, Ni H, Skeen TH, Andropoulos DB. Results of a phase 1 multicentre investigation of dexmedetomidine bolus and infusion in corrective infant cardiac surgery. Br J Anaesth. 2019 12; 123(6):839-852. PMID: 31623840.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  9. Hettiarachchi GK, Katneni UK, Hunt RC, Kames JM, Athey JC, Bar H, Sauna ZE, McGill JR, Ibla JC, Kimchi-Sarfaty C. Translational and transcriptional responses in human primary hepatocytes under hypoxia. Am J Physiol Gastrointest Liver Physiol. 2019 06 01; 316(6):G720-G734. PMID: 30920299.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  10. Katneni UK, Ibla JC, Hunt R, Schiller T, Kimchi-Sarfaty C. von Willebrand factor/ADAMTS-13 interactions at birth: implications for thrombosis in the neonatal period. J Thromb Haemost. 2019 Mar; 17(3):429-440. PMID: 30593735.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Emani S, Sleeper LA, Faraoni D, Mulone M, Diallo F, DiNardo JA, Ibla J, Emani SM. Thromboelastography Is Associated With Surrogates for Bleeding After Pediatric Cardiac Operations. Ann Thorac Surg. 2018 09; 106(3):799-806. PMID: 29753821.
    Citations: 1     Fields:    Translation:Humans
  12. Nathan M, Tishler B, Gauvreau K, Matte GS, Howe RJ, Durham L, Boyle S, Mathieu D, Fynn-Thompson F, DiNardo JA, Ibla JC. A red cell preservation strategy reduces postoperative transfusions in pediatric heart surgery patients. Paediatr Anaesth. 2018 05; 28(5):450-457. PMID: 29575610.
    Citations:    Fields:    Translation:HumansCells
  13. Fang ZA, Bernier R, Emani S, Emani S, Matte G, DiNardo JA, Faraoni D, Ibla JC. Preoperative Thromboelastographic Profile of Patients with Congenital Heart Disease: Association of Hypercoagulability and Decreased Heparin Response. J Cardiothorac Vasc Anesth. 2018 08; 32(4):1657-1663. PMID: 29331555.
    Citations:    Fields:    Translation:Humans
  14. Hunt R, Hoffman CM, Emani S, Emani S, Trenor CC, Emani SM, Faraoni D, Kimchi-Sarfaty C, Ibla JC. Elevated preoperative von Willebrand factor is associated with perioperative thrombosis in infants and neonates with congenital heart disease. J Thromb Haemost. 2017 12; 15(12):2306-2316. PMID: 28981194.
    Citations: 1     Fields:    Translation:Humans
  15. Katneni UK, Hunt R, Hettiarachchi GK, Hamasaki-Katagiri N, Kimchi-Sarfaty C, Ibla JC. Compounding variants rescue the effect of a deleterious ADAMTS13 mutation in a child with severe congenital heart disease. Thromb Res. 2017 10; 158:98-101. PMID: 28866379.
    Citations:    Fields:    Translation:Humans
  16. Faraoni D, Emani S, Halpin E, Bernier R, Emani SM, DiNardo JA, Ibla JC. Relationship Between Transfusion of Blood Products and the Incidence of Thrombotic Complications in Neonates and Infants Undergoing Cardiac Surgery. J Cardiothorac Vasc Anesth. 2017 Dec; 31(6):1943-1948. PMID: 28533072.
    Citations: 4     Fields:    Translation:Humans
  17. Liu JR, Liu Q, Khoury J, Li YJ, Han XH, Li J, Ibla JC. Hypoxic preconditioning decreases nuclear factor ?B activity via Disrupted in Schizophrenia-1. Int J Biochem Cell Biol. 2016 Jan; 70:140-8. PMID: 26615762.
    Citations:    Fields:    Translation:HumansAnimalsCells
  18. Wang RF, Zhang LH, Shan LH, Sun WG, Chai CC, Wu HM, Ibla JC, Wang LF, Liu JR. Effects of the fibroblast activation protein on the invasion and migration of gastric cancer. Exp Mol Pathol. 2013 Dec; 95(3):350-56. PMID: 24422232.
    Citations: 18     Fields:    Translation:HumansCells
  19. Wang RF, Zhang LH, Shan LH, Sun WG, Chai CC, Wu HM, Ibla JC, Wang LF, Liu JR. Effects of the fibroblast activation protein on the invasion and migration of gastric cancer. Exp Mol Pathol. 2013 Oct 25. PMID: 24512698.
    Citations:    Fields:    
  20. Dong HW, Zhang S, Sun WG, Liu Q, Ibla JC, Soriano SG, Han XH, Liu LX, Li MS, Liu JR. ß-Ionone arrests cell cycle of gastric carcinoma cancer cells by a MAPK pathway. Arch Toxicol. 2013 Oct; 87(10):1797-808. PMID: 23536271.
    Citations: 6     Fields:    Translation:HumansCells
  21. Ibla JC, Khoury J. Methods to assess tissue permeability. Methods Mol Biol. 2013; 1066:81-8. PMID: 23955735.
    Citations: 2     Fields:    Translation:AnimalsCells
  22. Liu Q, Dong HW, Sun WG, Liu M, Ibla JC, Liu LX, Parry JW, Han XH, Li MS, Liu JR. Apoptosis initiation of ß-ionone in SGC-7901 gastric carcinoma cancer cells via a PI3K-AKT pathway. Arch Toxicol. 2013 Mar; 87(3):481-90. PMID: 23100158.
    Citations: 9     Fields:    Translation:HumansCells
  23. Soriano SG, Liu Q, Li J, Liu JR, Han XH, Kanter JL, Bajic D, Ibla JC. Ketamine activates cell cycle signaling and apoptosis in the neonatal rat brain. Anesthesiology. 2010 May; 112(5):1155-63. PMID: 20418696.
    Citations: 40     Fields:    Translation:Animals
  24. Jia-Ren Liu, Juan C. Ibla, Qian Liu, Xiaohui Han, Joseph Khoury. Disrupted in Schizophrenia-1 (DISC1)Regulates ATM-mediated NFkappaB Activation during Hypoxia and Re-oxygenation. FASEB meeting. 2010.
  25. Soriano SG, Liu JR, Liu Q, Bajic D and Ibla JC. Dexmedetomidine is less pro-apoptotic than ketamine in the neonatal rat brain. ASA. 2009.
  26. Liu Q, Li J, Khoury J, Colgan SP, Ibla JC. Adenosine signaling mediates SUMO-1 modification of IkappaBalpha during hypoxia and reoxygenation. J Biol Chem. 2009 May 15; 284(20):13686-13695. PMID: 19297320.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  27. Liu Q, Li J, Khoury J, Colgan SP and Ibla JC. Adenosine signaling mediates small ubiquitin-like protein (sumo-1) modification of IKappaBalpha during hypoxia and re-oxygenation. In press, Journal of Biological Chemistry. 2009.
  28. Ibla JC. Anesthesia for Pediatric Thoracic Surgery. Springer Science and Business Media ( Phillip Hartigan). 2009.
  29. Ibla JC, Hayashi H, Bajic D and Soriano SG. Prolonged exposure to ketamine increases brain derived neurotrophic factor levels in developing rat brains. 2009; 4(1):11-16.
  30. Ibla JC, Hayashi H, Bajic D, Soriano SG. Prolonged exposure to ketamine increases brain derived neurotrophic factor levels in developing rat brains. Curr Drug Saf. 2009 Jan; 4(1):11-6. PMID: 19149520.
    Citations: 11     Fields:    Translation:Animals
  31. Soriano SG, Li J, Liu Q, Kanter J, Ibla JC. Ketamine Activates Cell Cycle Events and Apoptosis in the Neonatal Rat Brain. ASA, 2008. 2008.
  32. Soriano Sg, Li J, Liu Q, Athimaran U, Ibla JC. Noxious Stimulation Attenuates Ketamine and Isoflurane-Induced Neuroapoptosis in the P7 Rat Brain. ASA, 2008. 2008.
  33. Juan C. Ibla, Joseph Khoury, Andrew Neish and Sean P. Colgan. Pulmonary anti-inflammatory adaptation to hypoxia through adenosine-mediated Cullin-1 Deneddylation. ASA, San Francisco CA. 2007.
  34. Juan C. Ibla. Central Venous Access in the Neonate. 2007.
  35. Eckle T, Füllbier L, Wehrmann M, Khoury J, Mittelbronn M, Ibla J, Rosenberger P, Eltzschig HK. Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury. J Immunol. 2007 Jun 15; 178(12):8127-37. PMID: 17548651.
    Citations: 118     Fields:    Translation:HumansAnimalsCells
  36. Ibla JC, Khoury J, Neish AS and Colgan SP. Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. FASEB meeting, 2007. Washington DC. 2007.
  37. Eckle T, Fullbier L, Wehrmann M, Khoury J, Ibla J, Rosenberg P and Eltzschig KH. Identification of ecto-nucleotidases CD39 and CD73 in innate protection during acute lung injury. J Immunol, In press. 2007.
  38. Khoury J, Ibla JC, Neish AS, Colgan SP. Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation. J Clin Invest. 2007 Mar; 117(3):703-11. PMID: 17318263.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  39. Juan C. Ibla and John H. Arnold. Mechanical Ventilation of the Neonate. Cambridge Press. 2007.
  40. Neukirchner G, Kim HG, Kang V, Okada N and Ibla JC. Early tracheal extubation after liver or multivisceral transplantation in infant and toddler recipients: Is it safe?. ASA. 2006.
  41. Ibla JC, Khoury J, Kong T, Robinson A and Colgan SP. Transcriptional Repression of Na-K-2Cl-cotransporter NKCC1 by Hypoxia Inducible Factor-1. AJP. Cell Physiol. 2006; 291:C282-C289.
  42. Khoury J, Ibla JC, Colgan SP. Identification of Molecular Anti-inflammatory Mechanisms of Adenosine: Cullin-1 Denedddylation during Hypoxic Preconditioning. 8th International Symposium on Adenosine and Adenine Nucleotides. 2006.
  43. Eltzschig HK, Faigle M, Knapp S, Karhausen J, Ibla J, Rosenberger P, Odegard KC, Laussen PC, Thompson LF, Colgan SP. Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26. Blood. 2006 Sep 01; 108(5):1602-10. PMID: 16670267.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  44. Eltzschig HK, Faigle M, Knapp S, Karhausen J, Ibla J, Rosenberger P, Odegard KC, Laussen PC, Thompson LF, Colgan SP. Endothelial Catabolism of Extracellular Adenosine during Hypoxia: Role of Surface Adenosine Deaminase and CD26. Blood. Epub ahead of print. 2006.
  45. Colgan SP, Khoury J, Robinson A, Kong T, Ibla JC. HIF-dependent Repression of Na-K-2Clcotransporter (NKCC1) in Hypoxia. FASEB meeting 2006. San Francisco CA. 2006.
  46. Ibla JC, Khoury J, Kong T, Robinson A, Colgan SP. Transcriptional repression of Na-K-2Cl cotransporter NKCC1 by hypoxia-inducible factor-1. . 2006 Aug; 291(2):C282-9. PMID: 16571862.
    Citations: 13     Translation:AnimalsCells
  47. Kovatsis PG, Dumont RS, Ibla JC, Kang BV, Koka BV, Kussman BD, Myers LB, Okada NA, Seefelder C. Anesthetic Management of a Patient with Hepatopulmonary Syndrome, Prolonged QTc Interval and Panhypopituitarism for Liver Transplantation. Society of Pediatric Anesthesia meeting. 2006.
  48. Ibla JC, Khoury J. Methods to assess tissue permeability. Methods Mol Biol. 2006; 341:111-7. PMID: 16799193.
    Citations: 5     Fields:    Translation:AnimalsCells
  49. Khoury J, Ibla JC, Kong T, Robinson A, Colgan Sp. Transcriptional Repression of Na-K-2Cl-cotransporter (NKCC1) by Hypoxia Inducible Factor 1. Keystone Symposia. 2005.
  50. Kang VB, Soriano SG, Madril DR and Ibla JC. Anesthesia for Emergent non-cardiac Surgery in neonates with Unpalliated Hypoplastic Left Heart Syndrome. SPA/AAP. 2005.
  51. Juan C. Ibla, M.D. and Joseph Khoury,Ph.D. Methods in Molecular Biology. Methods to Assess Tissue Permeability. Cell-Cell Interactions. 2005; 341:111-117.
  52. Thompson LF, Eltzschig HK, Ibla JC, Van De Wiele CJ, Resta R, Morote-Garcia JC, Colgan SP. Crucial role for ecto-5'-nucleotidase (CD73) in vascular leakage during hypoxia. J Exp Med. 2004 Dec 06; 200(11):1395-405. PMID: 15583013.
    Citations: 230     Fields:    Translation:Animals
  53. Ibla JC, Eltzschig HK, Resta R, Colgan SP and Thompson LF. Critical Role for ecto-5'nucleotidase in pulmonary vascular permeability during hypoxia. ASA. 2004.
  54. Eltzschig HK, Thompson LF, Karhausen J, Cotta RJ, Ibla JC, Robson SC, Colgan SP. Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism. Blood. 2004 Dec 15; 104(13):3986-92. PMID: 15319286.
    Citations: 151     Fields:    Translation:HumansCells
  55. Ibla JC, Eltzschig HK, Jacobson K, Enjoyoji K, Robson S and Colgan SP. The dynamic influences of hypoxia on extracellular nucleotide metabolism and nucleoside signalling. Purines 2004. 2004.
  56. Ibla JC, Hayashi H and Soriano SG. Prolonged Ketamine Administration increases brain derived neurotrophic factor in developing rat brains. 2003.
  57. Eltzschig HK, Ibla JC, Furuta GT, Leonard MO, Jacobson KA, Enjyoji K, Robson SC, Colgan SP. Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. J Exp Med. 2003 Sep 01; 198(5):783-96. PMID: 12939345.
    Citations: 218     Fields:    Translation:HumansCells
  58. Karhausen J, Ibla JC, Colgan SP. Implications of hypoxia on mucosal barrier function. Cell Mol Biol (Noisy-le-grand). 2003 Feb; 49(1):77-87. PMID: 12839339.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  59. Ibla JC, Shamberger RC, DiCanzio J, Zurakowski D, Koka BV, Lillehei CW. Lung growth after reduced size transplantation in a sheep model. Transplantation. 1999 Jan 27; 67(2):233-40. PMID: 10075586.
    Citations: 3     Fields:    Translation:Animals
  60. Nobuhara KK, DiFiore JW, Ibla JC, Siddiqui AM, Ferretti ML, Fauza DO, Schnitzer JJ, Wilson JM. Insulin-like growth factor-I gene expression in three models of accelerated lung growth. J Pediatr Surg. 1998 Jul; 33(7):1057-60; discussion 1061. PMID: 9694094.
    Citations: 5     Fields:    Translation:Animals
  61. Tsakayannis DE, Siddiqui AM, Kozakewich H, Nobuhara KK, Ibla JC, Perry SD, Lillehei CW. The use of expandable metallic stents for acute tracheal stenosis in the growing lamb. J Pediatr Surg. 1998 Jul; 33(7):1038-41; discussion 1041-2. PMID: 9694090.
    Citations: 1     Fields:    Translation:Animals
  62. Ibla JC, Shamberger RC, DiCanzio J, Zurakowski D, Koka VB and Lillehei CW. Lung growth following reduced-size lung transplantation in a sheep model. 1998.
  63. Doctor A, Ibla JC, Grenier BM, Zurakowski D, Ferretti ML, Thompson JE, Lillehei CW, Arnold JH. Pulmonary blood flow distribution during partial liquid ventilation. J Appl Physiol (1985). 1998 May; 84(5):1540-50. PMID: 9572797.
    Citations: 7     Fields:    Translation:Animals
  64. Nobuhara KK, DiFiore JW, Ibla JC, Siddiqui AM, Ferreti M, Schitnzer JJ and Wilson JM. Insulin like growth factor I gene expression in three models of accelerated lung growth. 1997.
  65. Tsakayannis DE, Siddiqui AM, Ibla JC, Kozakewich H, Nobuhara KK, Perry S and Lillehei CW. The use of expandable metallic stents for acute tracheal stenosis in the growing lamb. 1997.
  66. Ibla JC, Arnold JH, Thompson JE, Breuer CK, Benjamin PK, Lillehei CW. Effects of nitric oxide on hyperinflation-induced pulmonary hypertension in the isolated-perfused lung. Crit Care Med. 1996 Aug; 24(8):1388-95. PMID: 8706496.
    Citations:    Fields:    Translation:Animals
  67. Nobuhara JJ, Slavin R, Ibla JC, Fauza DO, Fackler JC, Wilson JM. Continuos intrapulmonary distention with perfluorocarbon does not result in postnatal lung growth in adult sheep. 1996.
  68. Doctor A, Ibla JC, Grenier B, Thompson J, Lillehei CW and Arnold JH. Redistribution of pulmonary blood flow during partial liquid ventilation. 1996.
  69. Forbess JM, Ibla JC, Lidov HG, Cioffi MA, Hiramatsu T, Laussen P, Miura T, Jonas RA. University of Wisconsin cerebroplegia in a piglet survival model of circulatory arrest. Ann Thorac Surg. 1995 Dec; 60(6 Suppl):S494-500. PMID: 8604918.
    Citations: 4     Fields:    Translation:Animals
  70. Ibla JC, Arnold JH, Thompson JE, Breuer CK, Benjamin PK and Lillehei CW. The effect of nitric oxide on overdistention pulmonary hypertension in the isolated sheep lung model. 1995.
  71. Ibla JC, Rodriguez G, Pacheco C. Limb fractures associated with craneoencephalic trauma. 1991.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.