Harvard Catalyst Profiles

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Stephen Jun Fei Chong, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kornauth C, Herbaux C, Boidol B, Guillemette C, Caron P, Mayerhöfer ME, Poulain S, Tournilhac O, Pemovska T, Chong SJF, Van der Kouwe E, Kazianka L, Hopfinger G, Heintel D, Jäger R, Raderer M, Jäger U, Simonitsch-Klupp I, Sperr WR, Kubicek S, Davids MS, Staber PB. Rationale for the combination of venetoclax and ibrutinib in T-prolymphocytic leukemia. Haematologica. 2021 08 01; 106(8):2251-2256. PMID: 33626863.
    Citations: 4     Fields:    Translation:Humans
  2. Herbaux C, Kornauth C, Poulain S, Chong SJF, Collins MC, Valentin R, Hackett L, Tournilhac O, Lemonnier F, Dupuis J, Daniel A, Tomowiak C, Laribi K, Renaud L, Roos-Weil D, Rossi C, Van Den Neste E, Leyronnas C, Merabet F, Malfuson JV, Tiab M, Ysebaert L, Ng S, Morschhauser F, Staber PB, Davids MS. BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia. Blood. 2021 06 24; 137(25):3495-3506. PMID: 33598678.
    Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
  3. Ngoi NY, Liew AQ, Chong SJF, Davids MS, Clement MV, Pervaiz S. The redox-senescence axis and its therapeutic targeting. Redox Biol. 2021 09; 45:102032. PMID: 34147844.
    Citations: 13     Fields:    Translation:Cells
  4. Qu J, Zheng B, Ohuchida K, Feng H, Chong SJF, Zhang X, Liang R, Liu Z, Shirahane K, Mizumoto K, Gong P, Nakamura M. PIK3CB is involved in metastasis through the regulation of cell adhesion to collagen I in pancreatic cancer. J Adv Res. 2021 11; 33:127-140. PMID: 34603784; PMCID: PMC8463925.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  5. Yee YH, Chong SJF, Kong LR, Goh BC, Pervaiz S. Sustained IKKß phosphorylation and NF-?B activation by superoxide-induced peroxynitrite-mediated nitrotyrosine modification of B56?3 and PP2A inactivation. Redox Biol. 2021 05; 41:101834. PMID: 33838472.
    Citations: 4     Fields:    Translation:Cells
  6. Chong SJF, Iskandar K, Lai JXH, Qu J, Raman D, Valentin R, Herbaux C, Collins M, Low ICC, Loh T, Davids M, Pervaiz S. Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism. Nucleic Acids Res. 2020 12 16; 48(22):12727-12745. PMID: 33245769.
    Citations: 10     Fields:    Translation:HumansCells
  7. Zheng B, Qu J, Ohuchida K, Feng H, Chong SJF, Yan Z, Piao Y, Liu P, Sheng N, Eguchi D, Ohtsuka T, Mizumoto K, Liu Z, Pervaiz S, Gong P, Nakamura M. LAMA4 upregulation is associated with high liver metastasis potential and poor survival outcome of Pancreatic Cancer. Theranostics. 2020; 10(22):10274-10289. PMID: 32929348.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  8. Raman D, Chong SJF, Iskandar K, Hirpara JL, Pervaiz S. Peroxynitrite promotes serine-62 phosphorylation-dependent stabilization of the oncoprotein c-Myc. Redox Biol. 2020 07; 34:101587. PMID: 32512497; PMCID: PMC7280771.
    Citations: 2     Fields:    Translation:Cells
  9. Chong SJF, Marchi S, Petroni G, Kroemer G, Galluzzi L, Pervaiz S. Noncanonical Cell Fate Regulation by Bcl-2 Proteins. Trends Cell Biol. 2020 07; 30(7):537-555. PMID: 32307222.
    Citations: 29     Fields:    Translation:HumansAnimals
  10. Chong SJF, Davids MS. Breaking through BCL-2 inhibition in CLL. Blood. 2020 03 05; 135(10):709-711. PMID: 32135019.
    Citations: 3     Fields:    Translation:Humans
  11. Chong SJF, Lai JXH, Qu J, Hirpara J, Kang J, Swaminathan K, Loh T, Kumar A, Vali S, Abbasi T, Pervaiz S. A feedforward relationship between active Rac1 and phosphorylated Bcl-2 is critical for sustaining Bcl-2 phosphorylation and promoting cancer progression. Cancer Lett. 2019 08 10; 457:151-167. PMID: 31103719.
    Citations: 12     Fields:    Translation:HumansCells
  12. Chong SJF, Lai JXH, Eu JQ, Bellot GL, Pervaiz S. Reactive Oxygen Species and Oncoprotein Signaling-A Dangerous Liaison. Antioxid Redox Signal. 2018 12 01; 29(16):1553-1588. PMID: 29186971.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  13. Yee YH, Chong SJ, Pervaiz S. The anti-oxidant and pro-oxidant dichotomy of Bcl-2. Biol Chem. 2016 07 01; 397(7):585-93. PMID: 27060742.
    Citations:    Fields:    Translation:HumansAnimalsCells
  14. Kang J, Chong SJ, Ooi VZ, Vali S, Kumar A, Kapoor S, Abbasi T, Hirpara JL, Loh T, Goh BC, Pervaiz S. Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide. Oncotarget. 2015 Oct 27; 6(33):34191-205. PMID: 26430964.
    Citations: 17     Fields:    Translation:HumansCells
  15. Chong SJ, Low IC, Pervaiz S. Mitochondrial ROS and involvement of Bcl-2 as a mitochondrial ROS regulator. Mitochondrion. 2014 Nov; 19 Pt A:39-48. PMID: 24954615.
    Citations: 49     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.