Harvard Catalyst Profiles

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Insoo Hyun, Ph.D.

Other Positions

Stanford University, Palo Alto, CABA06/1992Philosophy
Stanford University, Palo Alto, CAMA06/1993Philosophy
Brown University, Providence, RIPhD05/1998Philosophy

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hyun I. The responsibility for ethical procurement of human embryos and gametes. Nat Biotechnol. 2021 Dec; 39(12):1499-1500. PMID: 34853479.
    Citations:    Fields:    
  2. MacDuffie KE, Hyun I, Krogen MM, Dempsey JC, Murry CE, Copp AJ, Glass IA, Doherty D. Rescuing human fetal tissue research in the United States: A call for additional regulatory reform. Stem Cell Reports. 2021 12 14; 16(12):2839-2843. PMID: 34822773.
    Citations:    Fields:    Translation:Humans
  3. Lovell-Badge R, Anthony E, Barker RA, Bubela T, Brivanlou AH, Carpenter M, Charo RA, Clark A, Clayton E, Cong Y, Daley GQ, Fu J, Fujita M, Greenfield A, Goldman SA, Hill L, Hyun I, Isasi R, Kahn J, Kato K, Kim JS, Kimmelman J, Knoblich JA, Mathews D, Montserrat N, Mosher J, Munsie M, Nakauchi H, Naldini L, Naughton G, Niakan K, Ogbogu U, Pedersen R, Rivron N, Rooke H, Rossant J, Round J, Saitou M, Sipp D, Steffann J, Sugarman J, Surani A, Takahashi J, Tang F, Turner L, Zettler PJ, Zhai X. ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem Cell Reports. 2021 06 08; 16(6):1398-1408. PMID: 34048692.
    Citations: 10     Fields:    Translation:HumansCells
  4. Hyun I, Clayton EW, Cong Y, Fujita M, Goldman SA, Hill LR, Monserrat N, Nakauchi H, Pedersen RA, Rooke HM, Takahashi J, Knoblich JA. ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts. Stem Cell Reports. 2021 06 08; 16(6):1409-1415. PMID: 34048695.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  5. Hyun I, Bredenoord AL, Briscoe J, Klipstein S, Tan T. Human embryo research beyond the primitive streak. Science. 2021 Mar 05; 371(6533):998-1000. PMID: 33674483.
    Citations: 6     Fields:    Translation:Humans
  6. Hyun I. Moonshots and Other Metaphors: The BRAIN Initiative. AJOB Neurosci. 2020 Jul-Sep; 11(3):198-200. PMID: 32716752.
    Citations:    Fields:    
  7. Hyun I, Scharf-Deering JC, Lunshof JE. Ethical issues related to brain organoid research. Brain Res. 2020 04 01; 1732:146653. PMID: 32017900.
    Citations: 8     Fields:    Translation:HumansAnimals
  8. Hyun I, Munsie M, Pera MF, Rivron NC, Rossant J. Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells. Stem Cell Reports. 2020 02 11; 14(2):169-174. PMID: 31951813.
    Citations: 19     Fields:    Translation:HumansCells
  9. Hyun I. Ethical considerations for human-animal neurological chimera research: mouse models and beyond. EMBO J. 2019 10 04; 38(21):e103331. PMID: 31602659.
    Citations: 3     Fields:    Translation:HumansAnimals
  10. Hyun I. Informed Consent Issues for Cell Donors. Methods Mol Biol. 2019; 2005:67-74. PMID: 31175646.
    Citations:    Fields:    Translation:Humans
  11. Hyun I. Ethical Standards for Chimera Research Oversight. Methods Mol Biol. 2019; 2005:165-171. PMID: 31175652.
    Citations: 2     Fields:    Translation:HumansAnimals
  12. De Los Angeles A, Hyun I, Latham SR, Elsworth JD, Redmond DE. Human-Monkey Chimeras for Modeling Human Disease: Opportunities and Challenges. Stem Cells Dev. 2018 12 01; 27(23):1599-1604. PMID: 30319057.
    Citations: 2     Fields:    Translation:HumansAnimals
  13. Rivron N, Pera M, Rossant J, Martinez Arias A, Zernicka-Goetz M, Fu J, van den Brink S, Bredenoord A, Dondorp W, de Wert G, Hyun I, Munsie M, Isasi R. Debate ethics of embryo models from stem cells. Nature. 2018 12; 564(7735):183-185. PMID: 30542177.
    Citations: 28     Fields:    Translation:HumansAnimals
  14. Ogbogu U, Zarzeczny A, Baltz J, Bedford P, Du J, Hyun I, Jaafar Y, Jurisicova A, Kleiderman E, Koukio Y, Knoppers BM, Leader A, Master Z, Nguyen MT, Noohi F, Ravitsky V, Toews M. Research on Human Embryos and Reproductive Materials: Revisiting Canadian Law and Policy. Healthc Policy. 2018 02; 13(3):10-19. PMID: 29595433.
    Citations: 1     Fields:    Translation:Humans
  15. Hurlbut JB, Hyun I, Levine AD, Lovell-Badge R, Lunshof JE, Matthews KRW, Mills P, Murdoch A, Pera MF, Scott CT, Tizzard J, Warnock M, Zernicka-Goetz M, Zhou Q, Zoloth L. Erratum: Revisiting the Warnock rule. Nat Biotechnol. 2017 12 08; 35(12):1211. PMID: 29220028.
    Citations:    Fields:    
  16. Hurlbut JB, Hyun I, Levine AD, Lovell-Badge R, Lunshof JE, Matthews KRW, Mills P, Murdoch A, Pera MF, Scott CT, Tizzard J, Warnock M, Zernicka-Goetz M, Zhou Q, Zoloth L. Revisiting the Warnock rule. Nat Biotechnol. 2017 11 09; 35(11):1029-1042. PMID: 29121021.
    Citations: 13     Fields:    Translation:HumansCells
  17. Hyun I, Osborn C. Query the merits of embryo editing for reproductive research now. Nat Biotechnol. 2017 11 09; 35(11):1023-1025. PMID: 29121025.
    Citations: 2     Fields:    Translation:Humans
  18. Hyun I. Engineering Ethics and Self-Organizing Models of Human Development: Opportunities and Challenges. Cell Stem Cell. 2017 Dec 07; 21(6):718-720. PMID: 28943028.
    Citations: 9     Fields:    Translation:Humans
  19. Bredenoord AL, Hyun I. Ethics of stem cell-derived gametes made in a dish: fertility for everyone? EMBO Mol Med. 2017 04; 9(4):396-398. PMID: 28279974.
    Citations: 7     Fields:    Translation:HumansCells
  20. Munsie M, Hyun I, Sugarman J. Ethical issues in human organoid and gastruloid research. Development. 2017 03 15; 144(6):942-945. PMID: 28292838.
    Citations: 15     Fields:    Translation:Humans
  21. Hyun I. Illusory fears must not stifle chimaera research. Nature. 2016 09 15; 537(7620):281. PMID: 27629603.
    Citations: 5     Fields:    Translation:HumansAnimals
  22. Hyun I. What's Wrong with Human/Nonhuman Chimera Research? PLoS Biol. 2016 08; 14(8):e1002535. PMID: 27574863.
    Citations: 7     Fields:    Translation:HumansAnimals
  23. Kimmelman J, Hyun I, Benvenisty N, Caulfield T, Heslop HE, Murry CE, Sipp D, Studer L, Sugarman J, Daley GQ. Policy: Global standards for stem-cell research. Nature. 2016 05 19; 533(7603):311-3. PMID: 27193661.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  24. Kimmelman J, Heslop HE, Sugarman J, Studer L, Benvenisty N, Caulfield T, Hyun I, Murry CE, Sipp D, Daley GQ. New ISSCR guidelines: clinical translation of stem cell research. Lancet. 2016 May 14; 387(10032):1979-81. PMID: 27179752.
    Citations: 13     Fields:    Translation:HumansPHPublic Health
  25. Hyun I, Wilkerson A, Johnston J. Embryology policy: Revisit the 14-day rule. Nature. 2016 05 12; 533(7602):169-71. PMID: 27172031.
    Citations: 49     Fields:    Translation:Humans
  26. Daley GQ, Hyun I, Apperley JF, Barker RA, Benvenisty N, Bredenoord AL, Breuer CK, Caulfield T, Cedars MI, Frey-Vasconcells J, Heslop HE, Jin Y, Lee RT, McCabe C, Munsie M, Murry CE, Piantadosi S, Rao M, Rooke HM, Sipp D, Studer L, Sugarman J, Takahashi M, Zimmerman M, Kimmelman J. Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines. Stem Cell Reports. 2016 06 14; 6(6):787-797. PMID: 27185282.
    Citations: 64     Fields:    Translation:HumansCells
  27. Hyun I. From naïve pluripotency to chimeras: a new ethical challenge? Development. 2015 Jan 01; 142(1):6-8. PMID: 25516963.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  28. Hyun I. Policy: Regulate embryos made for research. Nature. 2014 May 01; 509(7498):27-8. PMID: 24784200.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  29. Munsie M, Hyun I. A question of ethics: selling autologous stem cell therapies flaunts professional standards. Stem Cell Res. 2014 Nov; 13(3 Pt B):647-53. PMID: 24857592.
    Citations: 14     Fields:    Translation:Humans
  30. Hyun I. Therapeutic hope, spiritual distress, and the problem of stem cell tourism. Cell Stem Cell. 2013 May 02; 12(5):505-7. PMID: 23642359.
    Citations: 7     Fields:    Translation:HumansCells
  31. Haimes E, Skene L, Ballantyne AJ, Caulfield T, Goldstein LS, Hyun I, Kimmelman J, Robert JS, Roxland BE, Scott CT, Solbakk JH, Sugarman J, Taylor PL, Testa G. Position statement on the provision and procurement of human eggs for stem cell research. Cell Stem Cell. 2013 Mar 07; 12(3):285-91. PMID: 23472870.
    Citations: 5     Fields:    Translation:HumansCells
  32. Hyun I. The embryo potentiality argument revisited: "Once more unto the breach, dear friends". Am J Bioeth. 2013; 13(1):28-9. PMID: 23311836.
    Citations:    Fields:    Translation:HumansAnimalsCells
  33. Hyun I. Moving human SCNT research forward ethically. Cell Stem Cell. 2011 Oct 04; 9(4):295-7. PMID: 21982229.
    Citations: 4     Fields:    Translation:Humans
  34. Hyun I. Allowing innovative stem cell-based therapies outside of clinical trials: ethical and policy challenges. J Law Med Ethics. 2010; 38(2):277-85. PMID: 20579251.
    Citations: 10     Fields:    Translation:Humans
  35. Hyun I. The bioethics of stem cell research and therapy. J Clin Invest. 2010 Jan; 120(1):71-5. PMID: 20051638.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  36. Caulfield T, Scott C, Hyun I, Lovell-Badge R, Kato K, Zarzeczny A. Stem cell research policy and iPS cells. Nat Methods. 2010 Jan; 7(1):28-33. PMID: 20038953.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  37. Zarzeczny A, Scott C, Hyun I, Bennett J, Chandler J, Chargé S, Heine H, Isasi R, Kato K, Lovell-Badge R, McNagny K, Pei D, Rossant J, Surani A, Taylor PL, Ogbogu U, Caulfield T. iPS cells: mapping the policy issues. Cell. 2009 Dec 11; 139(6):1032-7. PMID: 20005794.
    Citations: 24     Fields:    Translation:HumansCells
  38. Skene L, Testa G, Hyun I, Jung KW, McNab A, Robertson J, Scott CT, Solbakk JH, Taylor P, Zoloth L. Ethics report on interspecies somatic cell nuclear transfer research. Cell Stem Cell. 2009 Jul 02; 5(1):27-30. PMID: 19570511.
    Citations: 4     Fields:    Translation:HumansCells
  39. Caulfield T, Zarzeczny A, McCormick J, Bubela T, Critchley C, Einsiedel E, Galipeau J, Harmon S, Huynh M, Hyun I, Illes J, Isasi R, Joly Y, Laurie G, Lomax G, Longstaff H, McDonald M, Murdoch C, Ogbogu U, Owen-Smith J, Pattinson S, Premji S, von Tigerstrom B, Winickoff DE. The stem cell research environment: a patchwork of patchworks. Stem Cell Rev Rep. 2009 Jun; 5(2):82-8. PMID: 19521798.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  40. Hyun I, Lindvall O, Ahrlund-Richter L, Cattaneo E, Cavazzana-Calvo M, Cossu G, De Luca M, Fox IJ, Gerstle C, Goldstein RA, Hermerén G, High KA, Kim HO, Lee HP, Levy-Lahad E, Li L, Lo B, Marshak DR, McNab A, Munsie M, Nakauchi H, Rao M, Rooke HM, Valles CS, Srivastava A, Sugarman J, Taylor PL, Veiga A, Wong AL, Zoloth L, Daley GQ. New ISSCR guidelines underscore major principles for responsible translational stem cell research. Cell Stem Cell. 2008 Dec 04; 3(6):607-9. PMID: 19041777.
    Citations: 83     Fields:    Translation:HumansAnimals
  41. Hyun I. Big bang theory: more reason to scrap Bush's stem cell policy. Hastings Cent Rep. 2008 Nov-Dec; 38(6):5-6; author reply 6. PMID: 19192704.
    Citations:    Fields:    Translation:HumansCells
  42. Hyun I. Stem cells from skin cells: the ethical questions. Hastings Cent Rep. 2008 Jan-Feb; 38(1):20-2. PMID: 18314804.
    Citations: 4     Fields:    Translation:HumansCells
  43. Hyun I. Clinical cultural competence and the threat of ethical relativism. Camb Q Healthc Ethics. 2008; 17(2):154-63. PMID: 18312730.
    Citations: 2     Fields:    Translation:Humans
  44. Hyun I, Hochedlinger K, Jaenisch R, Yamanaka S. New advances in iPS cell research do not obviate the need for human embryonic stem cells. Cell Stem Cell. 2007 Oct 11; 1(4):367-8. PMID: 18371375.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  45. Caulfield T, Ogbogu U, Nelson E, Einsiedel E, Knoppers B, McDonald M, Brunger F, Downey R, Fernando K, Galipeau J, Geransar R, Griener G, Grenier G, Hyun I, Isasi R, Kardel M, Knowles L, Kucic T, Lotjonen S, Lyall D, Magnus D, Mathews DJ, Nisbet M, Nisker J, Pare G, Pattinson S, Pullman D, Rudnicki M, Williams-Jones B, Zimmerman S. Stem cell research ethics: consensus statement on emerging issues. J Obstet Gynaecol Can. 2007 Oct; 29(10):843-8. PMID: 17915069.
    Citations: 5     Fields:    Translation:HumansCells
  46. Hyun I, Taylor P, Testa G, Dickens B, Jung KW, McNab A, Robertson J, Skene L, Zoloth L. Ethical standards for human-to-animal chimera experiments in stem cell research. Cell Stem Cell. 2007 Aug 16; 1(2):159-63. PMID: 18383627.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  47. Daley GQ, Ahrlund Richter L, Auerbach JM, Benvenisty N, Charo RA, Chen G, Deng HK, Goldstein LS, Hudson KL, Hyun I, Junn SC, Love J, Lee EH, McLaren A, Mummery CL, Nakatsuji N, Racowsky C, Rooke H, Rossant J, Schöler HR, Solbakk JH, Taylor P, Trounson AO, Weissman IL, Wilmut I, Yu J, Zoloth L. Ethics. The ISSCR guidelines for human embryonic stem cell research. Science. 2007 Feb 02; 315(5812):603-4. PMID: 17272706.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  48. Hyun I, Jung KW. ANT vs. SCNT. Hastings Cent Rep. 2006 Nov-Dec; 36(6):6; author reply 7. PMID: 17278862.
    Citations:    Fields:    Translation:HumansCells
  49. Hyun I, Jung KW. Human research cloning, embryos, and embryo-like artifacts. Hastings Cent Rep. 2006 Sep-Oct; 36(5):34-41. PMID: 17091700.
    Citations: 1     Fields:    Translation:HumansCells
  50. Hyun I. Fair payment or undue inducement? Nature. 2006 Aug 10; 442(7103):629-30. PMID: 16900181.
    Citations: 13     Fields:    Translation:HumansCells
  51. Hyun I. Magic eggs and the frontier of stem cell science. Hastings Cent Rep. 2006 Mar-Apr; 36(2):16-9. PMID: 16604893.
    Citations: 1     Fields:    Translation:HumansCells
  52. Hyun I, Griggins C, Weiss M, Robbins D, Robichaud A, Daly B. When patients do not have a proxy: a procedure for medical decision making when there is no one to speak for the patient. J Clin Ethics. 2006; 17(4):323-30. PMID: 17330723.
    Citations: 2     Fields:    Translation:Humans
  53. Jung KW, Hyun I. Oocyte and somatic cell procurement for stem cell research: the South Korean experience. Am J Bioeth. 2006 Jan-Feb; 6(1):W19-22. PMID: 16423766.
    Citations:    Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.