Harvard Catalyst Profiles

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Naoki Kaneko, Ph.D., D.D.S.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Kaneko N, Chen H, Perugino CA, Maehara T, Munemura R, Yokomizo S, Sameshima J, Diefenbach TJ, Premo KR, Chinju A, Miyahara Y, Sakamoto M, Moriyama M, Stone JH, Nakamura S, Pillai S. Cytotoxic CD8+ T cells may be drivers of tissue destruction in Sjögren's syndrome. Sci Rep. 2022 Sep 14; 12(1):15427. PMID: 36104369; PMCID: PMC9475031.
    Citations:    Fields:    Translation:HumansCells
  2. Munemura R, Maehara T, Murakami Y, Koga R, Aoyagi R, Kaneko N, Doi A, Perugino CA, Della-Torre E, Saeki T, Sato Y, Yamamoto H, Kiyoshima T, Stone JH, Pillai S, Nakamura S. Distinct disease-specific Tfh cell populations in 2 different fibrotic diseases: IgG4-related disease and Kimura disease. J Allergy Clin Immunol. 2022 08; 150(2):440-455.e17. PMID: 35568079.
    Citations: 2     Fields:    Translation:HumansCells
  3. Kaneko N, Boucau J, Kuo HH, Perugino C, Mahajan VS, Farmer JR, Liu H, Diefenbach TJ, Piechocka-Trocha A, Lefteri K, Waring MT, Premo KR, Walker BD, Li JZ, Gaiha G, Yu XG, Lichterfeld M, Padera RF, Pillai S. Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19. Clin Immunol. 2022 04; 237:108991. PMID: 35364330; PMCID: PMC8961941.
    Citations: 15     Fields:    Translation:HumansCells
  4. Rovati L, Kaneko N, Pedica F, Monno A, Maehara T, Perugino C, Lanzillotta M, Pecetta S, Stone JH, Doglioni C, Manfredi AA, Pillai S, Della-Torre E. Mer tyrosine kinase as a possible link between resolution of inflammation and tissue fibrosis in IgG4-related disease. Rheumatology (Oxford). 2021 10 02; 60(10):4929-4941. PMID: 33512463; PMCID: PMC8487308.
    Citations: 3     Fields:    Translation:HumansCells
  5. Kaneko N, Boucau J, Kuo HH, Perugino C, Mahajan VS, Farmer JR, Liu H, Diefenbach TJ, Piechocka-Trocha A, Lefteri K, Waring MT, Premo KR, Walker BD, Li JZ, Gaiha G, Yu XG, Lichterfeld M, Padera RF, Pillai S. Expansion of Cytotoxic CD4+ T cells in the lungs in severe COVID-19. medRxiv. 2021 Mar 26. PMID: 33791730; PMCID: PMC8010762.
    Citations:    
  6. Lanzillotta M, Sant'Angelo M, Kaneko N, Pillai S, Ponzoni M, Della-Torre E. Treating life-threatening TAFRO syndrome with interleukin-1 inhibition. Eur J Intern Med. 2021 05; 87:121-123. PMID: 33608160.
    Citations:    Fields:    Translation:Humans
  7. Allard-Chamard H, Alsufyani F, Kaneko N, Xing K, Perugino C, Mahajan VS, Wheat JL, Deepe GS, Loyd J, Pillai S. CD4+CTLs in Fibrosing Mediastinitis Linked to Histoplasma capsulatum. J Immunol. 2021 02 01; 206(3):524-530. PMID: 33328214; PMCID: PMC7978153.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  8. Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Alter G, Li JZ, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu XG, Padera RF, Pillai S. Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19. Cell. 2020 10 01; 183(1):143-157.e13. PMID: 32877699; PMCID: PMC7437499.
    Citations: 331     Fields:    Translation:HumansCellsPHPublic Health
  9. Minici C, Rigamonti E, Lanzillotta M, Monno A, Rovati L, Maehara T, Kaneko N, Deshpande V, Protti MP, De Monte L, Scielzo C, Crippa S, Arcidiacono PG, Dugnani E, Piemonti L, Falconi M, Pillai S, Manfredi AA, Della-Torre E. B lymphocytes contribute to stromal reaction in pancreatic ductal adenocarcinoma. Oncoimmunology. 2020 07 16; 9(1):1794359. PMID: 32923157.
    Citations: 11     Fields:    Translation:HumansCells
  10. Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Li J, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu X, Padera RF, Pillai S. The Loss of Bcl-6 Expressing T Follicular Helper Cells and the Absence of Germinal Centers in COVID-19. SSRN. 2020 Jul 16; 3652322. PMID: 32742244.
    Citations:    
  11. Perugino CA, Kaneko N, Maehara T, Mattoo H, Kers J, Allard-Chamard H, Mahajan VS, Liu H, Della-Torre E, Murphy SJH, Ghebremichael M, Wallace ZS, Bolster MB, Harvey LM, Mylvaganam G, Tuncay Y, Liang L, Montesi SB, Zhang X, Tinju A, Mochizuki K, Munemura R, Sakamoto M, Moriyama M, Nakamura S, Yosef N, Stone JH, Pillai S. CD4+ and CD8+ cytotoxic T lymphocytes may induce mesenchymal cell apoptosis in IgG4-related disease. J Allergy Clin Immunol. 2021 01; 147(1):368-382. PMID: 32485263; PMCID: PMC7704943.
    Citations: 23     Fields:    Translation:HumansCells
  12. Maehara T, Kaneko N, Perugino CA, Mattoo H, Kers J, Allard-Chamard H, Mahajan VS, Liu H, Murphy SJ, Ghebremichael M, Fox D, Payne AS, Lafyatis R, Stone JH, Khanna D, Pillai S. Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis. J Clin Invest. 2020 05 01; 130(5):2451-2464. PMID: 31990684; PMCID: PMC7190971.
    Citations: 49     Fields:    Translation:HumansCells
  13. Pillai S, Perugino C, Kaneko N. Immune mechanisms of fibrosis and inflammation in IgG4-related disease. Curr Opin Rheumatol. 2020 03; 32(2):146-151. PMID: 31842033.
    Citations: 9     Fields:    Translation:HumansCells
  14. Tanaka H, Kaneko N, Sakagami H, Matsuya T, Hiramoto M, Yamanaka Y, Mori M, Koshio H, Hirano M, Takeuchi M. Naquotinib exerts antitumor activity in activated B-cell-like diffuse large B-cell lymphoma. Leuk Res. 2020 01; 88:106286. PMID: 31865062.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  15. Maehara T, Munemura R, Shimizu M, Kakizoe N, Kaneko N, Murakami Y, Masafumi M, Kiyoshima T, Kawano S, Nakamura S. Tissue-infiltrating immune cells contribute to understanding the pathogenesis of Kimura disease: A case report. Medicine (Baltimore). 2019 Dec; 98(50):e18300. PMID: 31852109; PMCID: PMC6922356.
    Citations: 3     Fields:    Translation:HumansCells
  16. Haque ASMR, Moriyama M, Kubota K, Ishiguro N, Sakamoto M, Chinju A, Mochizuki K, Sakamoto T, Kaneko N, Munemura R, Maehara T, Tanaka A, Hayashida JN, Kawano S, Kiyoshima T, Nakamura S. CD206+ tumor-associated macrophages promote proliferation and invasion in oral squamous cell carcinoma via EGF production. Sci Rep. 2019 10 10; 9(1):14611. PMID: 31601953; PMCID: PMC6787225.
    Citations: 53     Fields:    Translation:HumansCells
  17. Ullman H, Jones J, Kaneko N, Tateshima S. Flow-directed micro-catheterisation technique over a detachable coil. BMJ Case Rep. 2019 Sep 04; 12(9). PMID: 31488452.
    Citations:    Fields:    Translation:Humans
  18. Sehara Y, Otsuka H, Kaneko N, Ando Y, Sawada M. Significance of N-isopropyl-[123I] p-iodoamphetamine single-photon emission computed tomography in detection of responsible hypoperfusion in hemichorea. J Clin Neurosci. 2019 Dec; 70:260-263. PMID: 31447357.
    Citations:    Fields:    Translation:Humans
  19. Della-Torre E, Rigamonti E, Perugino C, Baghai-Sain S, Sun N, Kaneko N, Maehara T, Rovati L, Ponzoni M, Milani R, Lanzillotta M, Mahajan V, Mattoo H, Molineris I, Deshpande V, Stone JH, Falconi M, Manfredi AA, Pillai S. B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease. J Allergy Clin Immunol. 2020 03; 145(3):968-981.e14. PMID: 31319101; PMCID: PMC6960365.
    Citations: 27     Fields:    Translation:HumansCells
  20. Tanaka H, Sakagami H, Kaneko N, Konagai S, Yamamoto H, Matsuya T, Yuri M, Yamanaka Y, Mori M, Takeuchi M, Koshio H, Hirano M, Kuromitsu S. Mutant-Selective Irreversible EGFR Inhibitor, Naquotinib, Inhibits Tumor Growth in NSCLC Models with EGFR-Activating Mutations, T790M Mutation, and AXL Overexpression. Mol Cancer Ther. 2019 08; 18(8):1366-1373. PMID: 31092564.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  21. Sakai N, Imamura H, Arimura K, Funatsu T, Beppu M, Suzuki K, Adachi H, Okuda T, Matsui Y, Kawabata S, Akiyama R, Horiuchi K, Tani S, Adachi H, Sakai C, Kaneko N, Tateshima S. PulseRider-Assisted Coil Embolization for Treatment of Intracranial Bifurcation Aneurysms: A Single-Center Case Series with 24-Month Follow-up. World Neurosurg. 2019 Aug; 128:e461-e467. PMID: 31042599.
    Citations: 8     Fields:    Translation:Humans
  22. Ueno Y, Mori M, Kamiyama Y, Saito R, Kaneko N, Isshiki E, Kuromitsu S, Takeuchi M. Evaluation of gilteritinib in combination with chemotherapy in preclinical models of FLT3-ITD+ acute myeloid leukemia. Oncotarget. 2019 Apr 02; 10(26):2530-2545. PMID: 31069015; PMCID: PMC6493465.
    Citations: 11     Fields:    
  23. Kaneko N, Minhas A, Tateshima S, Colby GP, Szeder V, Hinman JD, Nour M, Jahan R, Duckwiler G. Pre-procedural simulation for precision stent-assisted coiling of cerebral aneurysm. Interv Neuroradiol. 2019 Aug; 25(4):419-422. PMID: 30922200.
    Citations: 1     Fields:    Translation:Humans
  24. Namba K, Higaki A, Kaneko N, Nemoto S, Kawai K. Precision microcatheter shaping in vertebrobasilar aneurysm coiling. Interv Neuroradiol. 2019 Aug; 25(4):423-429. PMID: 30803335.
    Citations: 1     Fields:    Translation:Humans
  25. Sehara Y, Inaba T, Urabe T, Kurosaki F, Urabe M, Kaneko N, Shimazaki K, Kawai K, Mizukami H. Survivin overexpression via adeno-associated virus vector Rh10 ameliorates ischemic damage after middle cerebral artery occlusion in rats. Eur J Neurosci. 2018 12; 48(12):3466-3476. PMID: 30251448.
    Citations: 4     Fields:    Translation:AnimalsCells
  26. Sakai N, Imamura H, Adachi H, Tani S, Tokunaga S, Funatsu T, Suzuki K, Adachi H, Sasaki N, Kawabata S, Akiyama R, Horiuchi K, Ohara N, Kono T, Fujiwara S, Kaneko N, Tateshima S. First-in-man experience of the Versi Retriever in acute ischemic stroke. J Neurointerv Surg. 2019 Mar; 11(3):296-299. PMID: 30262657.
    Citations: 2     Fields:    Translation:Humans
  27. Kaneko N, Komuro Y, Yokota H, Tateshima S. Stent retrievers with segmented design improve the efficacy of thrombectomy in tortuous vessels. J Neurointerv Surg. 2019 Feb; 11(2):119-122. PMID: 30045949.
    Citations: 13     Fields:    Translation:HumansAnimals
  28. Nakayama M, Yamamoto S, Kaneko N, Mato N, Suzuki T, Hagiwara K. Use of low-cost three-dimensional printer to simulate grasping of bronchial foreign body. Respirol Case Rep. 2018 Oct; 6(7):e00351. PMID: 30009031; PMCID: PMC6041124.
    Citations:    
  29. Mitsuoka K, Kita A, Murakami Y, Shirasuna K, Noda A, Yamanaka K, Kaneko N, Miyoshi S. Predicting response to sepantronium bromide (YM155), a survivin suppressant, by PET imaging with [11C]YM155. Nucl Med Biol. 2018 Sep - Oct; 64-65:41-46. PMID: 30041149.
    Citations:    Fields:    Translation:HumansAnimalsCells
  30. Sehara Y, Shimazaki K, Kurosaki F, Kaneko N, Uchibori R, Urabe M, Kawai K, Mizukami H. Efficient transduction of adeno-associated virus vectors into gerbil hippocampus with an appropriate combination of viral capsids and promoters. Neurosci Lett. 2018 08 24; 682:27-31. PMID: 29885449.
    Citations: 1     Fields:    Translation:AnimalsCells
  31. Hashiguchi Y, Kawano S, Goto Y, Yasuda K, Kaneko N, Sakamoto T, Matsubara R, Jinno T, Maruse Y, Tanaka H, Morioka M, Hattori T, Tanaka S, Kiyoshima T, Nakamura S. Tumor-suppressive roles of ?Np63ß-miR-205 axis in epithelial-mesenchymal transition of oral squamous cell carcinoma via targeting ZEB1 and ZEB2. J Cell Physiol. 2018 10; 233(10):6565-6577. PMID: 29150940.
    Citations: 14     Fields:    Translation:HumansCells
  32. Nakamura A, Kaneko N, Villemagne VL, Kato T, Doecke J, Doré V, Fowler C, Li QX, Martins R, Rowe C, Tomita T, Matsuzaki K, Ishii K, Ishii K, Arahata Y, Iwamoto S, Ito K, Tanaka K, Masters CL, Yanagisawa K. High performance plasma amyloid-ß biomarkers for Alzheimer's disease. Nature. 2018 02 08; 554(7691):249-254. PMID: 29420472.
    Citations: 486     Fields:    Translation:Humans
  33. Tateshima S, Kaneko N, Yamada M, Duckwiler G, Vinuela F, Ogawa T. Increased affinity of endothelial cells to NiTi using ultraviolet irradiation: An in vitro study. J Biomed Mater Res A. 2018 04; 106(4):1034-1038. PMID: 29218785.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  34. Kaneko N, Kawano S, Yasuda K, Hashiguchi Y, Sakamoto T, Matsubara R, Goto Y, Jinno T, Maruse Y, Morioka M, Hattori T, Tanaka S, Tanaka H, Kiyoshima T, Nakamura S. Differential roles of kallikrein-related peptidase 6 in malignant transformation and ?Np63ß-mediated epithelial-mesenchymal transition of oral squamous cell carcinoma. Oral Oncol. 2017 12; 75:148-157. PMID: 29224812.
    Citations: 6     Fields:    Translation:HumansCells
  35. Nagai M, Kaneko N, Arai F, Kusaka G, Ishikawa M. Design of a Locator for Designing the Shortest Incision for a Polygonal Dural Window. Neurol Med Chir (Tokyo). 2017 Dec 15; 57(12):621-626. PMID: 28954944; PMCID: PMC5735224.
    Citations:    Fields:    Translation:Humans
  36. Sehara Y, Hayashi Y, Ohya K, Kaneko N, Sawada M. A Successfully Treated Case of Gastrointestinal Stromal Tumor Causing Severe Anemia and Localized Peritonitis Showing Angina Pectoris Resulting in Watershed Cerebral Infarction. Case Rep Med. 2017; 2017:6030561. PMID: 28912818; PMCID: PMC5585549.
    Citations: 1     
  37. Kaneko N, Mashiko T, Namba K, Tateshima S, Watanabe E, Kawai K. A patient-specific intracranial aneurysm model with endothelial lining: a novel in vitro approach to bridge the gap between biology and flow dynamics. J Neurointerv Surg. 2018 Mar; 10(3):306-309. PMID: 28652298.
    Citations: 27     Fields:    Translation:HumansAnimals
  38. Mori M, Kaneko N, Ueno Y, Yamada M, Tanaka R, Saito R, Shimada I, Mori K, Kuromitsu S. Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia. Invest New Drugs. 2017 10; 35(5):556-565. PMID: 28516360.
    Citations: 77     Fields:    Translation:HumansAnimalsCells
  39. Kaneko N, Tsunoda M, Mitsuhashi M, Okubo K, Takeshima T, Sehara Y, Nagai M, Kawai K. Ultrasound-Guided Fine-Needle Aspiration in the Neck Region Using an Optical See-Through Head-Mounted Display: A Randomized Controlled Trial. J Ultrasound Med. 2017 Oct; 36(10):2071-2077. PMID: 28504313.
    Citations: 4     Fields:    Translation:Humans
  40. Sakamoto T, Kawano S, Matsubara R, Goto Y, Jinno T, Maruse Y, Kaneko N, Hashiguchi Y, Hattori T, Tanaka S, Kitamura R, Kiyoshima T, Nakamura S. Critical roles of Wnt5a-Ror2 signaling in aggressiveness of tongue squamous cell carcinoma and production of matrix metalloproteinase-2 via ?Np63ß-mediated epithelial-mesenchymal transition. Oral Oncol. 2017 06; 69:15-25. PMID: 28559016.
    Citations: 8     Fields:    Translation:HumansCells
  41. Mashiko T, Kaneko N, Konno T, Otani K, Nagayama R, Watanabe E. Training in Cerebral Aneurysm Clipping Using Self-Made 3-Dimensional Models. J Surg Educ. 2017 Jul - Aug; 74(4):681-689. PMID: 28110854.
    Citations: 17     Fields:    Translation:Humans
  42. Kaneko N, Mashiko T, Ohnishi T, Ohta M, Namba K, Watanabe E, Kawai K. Manufacture of patient-specific vascular replicas for endovascular simulation using fast, low-cost method. Sci Rep. 2016 12 15; 6:39168. PMID: 27976687.
    Citations: 17     Fields:    Translation:Humans
  43. Konno T, Mashiko T, Oguma H, Kaneko N, Otani K, Watanabe E. [Rapid 3-Dimensional Models of Cerebral Aneurysm for Emergency Surgical Clipping]. No Shinkei Geka. 2016 Aug; 44(8):651-60. PMID: 27506842.
    Citations: 2     Fields:    Translation:Humans
  44. Kaneko N, Kawano S, Matsubara R, Goto Y, Jinno T, Maruse Y, Sakamoto T, Hashiguchi Y, Iida M, Nakamura S. Erratum to: Tongue squamous cell carcinoma producing both parathyroid hormone-related protein and granulocyte colony-stimulating factor: a case report and literature review. World J Surg Oncol. 2016 Jul 19; 14(1):187. PMID: 27435214.
    Citations:    Fields:    
  45. Kaneko N, Kawano S, Matsubara R, Goto Y, Jinno T, Maruse Y, Sakamoto T, Hashiguchi Y, Iida M, Nakamura S. Tongue squamous cell carcinoma producing both parathyroid hormone-related protein and granulocyte colony-stimulating factor: a case report and literature review. World J Surg Oncol. 2016 Jun 17; 14(1):161. PMID: 27316348.
    Citations: 6     Fields:    Translation:Humans
  46. Kaneko N, Sato M, Takeshima T, Sehara Y, Watanabe E. Ultrasound-guided central venous catheterization using an optical see-through head-mounted display: A pilot study. J Clin Ultrasound. 2016 Oct; 44(8):487-91. PMID: 27297681.
    Citations: 2     Fields:    Translation:Humans
  47. Mashiko T, Konno T, Kaneko N, Watanabe E. Training in Brain Retraction Using a Self-Made Three-Dimensional Model. World Neurosurg. 2015 Aug; 84(2):585-90. PMID: 25862113.
    Citations: 12     Fields:    Translation:Humans
  48. Namba K, Higaki A, Kaneko N, Mashiko T, Nemoto S, Watanabe E. Microcatheter Shaping for Intracranial Aneurysm Coiling Using the 3-Dimensional Printing Rapid Prototyping Technology: Preliminary Result in the First 10 Consecutive Cases. World Neurosurg. 2015 Jul; 84(1):178-86. PMID: 25779852.
    Citations: 30     Fields:    Translation:Humans
  49. Jinno T, Kawano S, Maruse Y, Matsubara R, Goto Y, Sakamoto T, Hashiguchi Y, Kaneko N, Tanaka H, Kitamura R, Toyoshima T, Jinno A, Moriyama M, Oobu K, Kiyoshima T, Nakamura S. Increased expression of interleukin-6 predicts poor response to chemoradiotherapy and unfavorable prognosis in oral squamous cell carcinoma. Oncol Rep. 2015 May; 33(5):2161-8. PMID: 25761055; PMCID: PMC4391588.
    Citations: 44     Fields:    Translation:Humans
  50. Mashiko T, Yang Q, Kaneko N, Konno T, Yamaguchi T, Watanabe E. [Pre-surgical simulation of microvascular decompression for hemifacial spasm using 3D-models]. No Shinkei Geka. 2015 Jan; 43(1):41-9. PMID: 25557098.
    Citations:    Fields:    Translation:Humans
  51. Hwang JY, Kaneko N, Noh KM, Pontarelli F, Zukin RS. The gene silencing transcription factor REST represses miR-132 expression in hippocampal neurons destined to die. J Mol Biol. 2014 Oct 09; 426(20):3454-66. PMID: 25108103.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  52. Kaneko N, Hwang JY, Gertner M, Pontarelli F, Zukin RS. Casein kinase 1 suppresses activation of REST in insulted hippocampal neurons and halts ischemia-induced neuronal death. J Neurosci. 2014 Apr 23; 34(17):6030-9. PMID: 24760862.
    Citations: 33     Fields:    Translation:AnimalsCells
  53. Kaneko N, Mitsuoka K, Amino N, Yamanaka K, Kita A, Mori M, Miyoshi S, Kuromitsu S. Combination of YM155, a survivin suppressant, with bendamustine and rituximab: a new combination therapy to treat relapsed/refractory diffuse large B-cell lymphoma. Clin Cancer Res. 2014 Apr 01; 20(7):1814-22. PMID: 24486595.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  54. Murphy JA, Stein IS, Lau CG, Peixoto RT, Aman TK, Kaneko N, Aromolaran K, Saulnier JL, Popescu GK, Sabatini BL, Hell JW, Zukin RS. Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines. J Neurosci. 2014 Jan 15; 34(3):869-79. PMID: 24431445.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  55. Kaneko N, Nakamura A, Washimi Y, Kato T, Sakurai T, Arahata Y, Bundo M, Takeda A, Niida S, Ito K, Toba K, Tanaka K, Yanagisawa K. Novel plasma biomarker surrogating cerebral amyloid deposition. Proc Jpn Acad Ser B Phys Biol Sci. 2014; 90(9):353-64. PMID: 25391320; PMCID: PMC4324927.
    Citations: 49     Fields:    Translation:Humans
  56. Kaneko N, Yamamoto R, Sato TA, Tanaka K. Identification and quantification of amyloid beta-related peptides in human plasma using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Proc Jpn Acad Ser B Phys Biol Sci. 2014; 90(3):104-17. PMID: 24621957.
    Citations: 24     Fields:    Translation:HumansCells
  57. Mashiko T, Otani K, Kawano R, Konno T, Kaneko N, Ito Y, Watanabe E. Development of three-dimensional hollow elastic model for cerebral aneurysm clipping simulation enabling rapid and low cost prototyping. World Neurosurg. 2015 Mar; 83(3):351-61. PMID: 24141000.
    Citations: 56     Fields:    Translation:Humans
  58. Kaneko N, Kita A, Yamanaka K, Mori M. Combination of YM155, a survivin suppressant with a STAT3 inhibitor: a new strategy to treat diffuse large B-cell lymphoma. Leuk Res. 2013 Sep; 37(9):1156-61. PMID: 23746965.
    Citations: 7     Fields:    Translation:HumansCells
  59. Kaneko N, Yoshimori T, Yamamoto R, Capon DJ, Shimada T, Sato TA, Tanaka K. Multi epitope-targeting immunoprecipitation using F(ab') fragments with high affinity and specificity for the enhanced detection of a peptide with matrix-assisted laser desorption ionization-time-of-flight mass spectrometry. Anal Chem. 2013 Mar 19; 85(6):3152-9. PMID: 23394179.
    Citations: 4     Fields:    Translation:Humans
  60. Hayashi A, Kaneko N, Tomihira C, Baba H. Sulfatide decrease in myelin influences formation of the paranodal axo-glial junction and conduction velocity in the sciatic nerve. Glia. 2013 Apr; 61(4):466-74. PMID: 23322453.
    Citations: 13     Fields:    Translation:AnimalsCells
  61. Kaneko N, Yamanaka K, Kita A, Tabata K, Akabane T, Mori M. Synergistic antitumor activities of sepantronium bromide (YM155), a survivin suppressant, in combination with microtubule-targeting agents in triple-negative breast cancer cells. Biol Pharm Bull. 2013; 36(12):1921-7. PMID: 24432379.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  62. Kaneko N, Gotoh A, Okamura N, Matsuo E, Terao S, Watanabe M, Yamada Y, Hamami G, Nakamura T, Ikekita M, Okumura K, Nishimura O. Potential tumor markers of renal cell carcinoma: a-enolase for postoperative follow up, and galectin-1 and galectin-3 for primary detection. Int J Urol. 2013 May; 20(5):530-5. PMID: 23113677.
    Citations: 12     Fields:    Translation:Humans
  63. Yamauchi T, Nakamura N, Hiramoto M, Yuri M, Yokota H, Naitou M, Takeuchi M, Yamanaka K, Kita A, Nakahara T, Kinoyama I, Matsuhisa A, Kaneko N, Koutoku H, Sasamata M, Kobori M, Katou M, Tawara S, Kawabata S, Furuichi K. Sepantronium bromide (YM155) induces disruption of the ILF3/p54(nrb) complex, which is required for survivin expression. Biochem Biophys Res Commun. 2012 Sep 07; 425(4):711-6. PMID: 22842455.
    Citations: 38     Fields:    Translation:HumansCells
  64. Kita A, Mitsuoka K, Kaneko N, Nakata M, Yamanaka K, Jitsuoka M, Miyoshi S, Noda A, Mori M, Nakahara T, Sasamata M. Sepantronium bromide (YM155) enhances response of human B-cell non-Hodgkin lymphoma to rituximab. J Pharmacol Exp Ther. 2012 Oct; 343(1):178-83. PMID: 22787117.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  65. Inagaki T, Kaneko N, Zukin RS, Castillo PE, Etgen AM. Estradiol attenuates ischemia-induced death of hippocampal neurons and enhances synaptic transmission in aged, long-term hormone-deprived female rats. PLoS One. 2012; 7(6):e38018. PMID: 22675505.
    Citations: 11     Fields:    Translation:AnimalsCells
  66. Nakamura N, Yamauchi T, Hiramoto M, Yuri M, Naito M, Takeuchi M, Yamanaka K, Kita A, Nakahara T, Kinoyama I, Matsuhisa A, Kaneko N, Koutoku H, Sasamata M, Yokota H, Kawabata S, Furuichi K. Interleukin enhancer-binding factor 3/NF110 is a target of YM155, a suppressant of survivin. Mol Cell Proteomics. 2012 Jul; 11(7):M111.013243. PMID: 22442257; PMCID: PMC3394938.
    Citations: 35     Fields:    Translation:HumansCells
  67. Yamanaka K, Nakahara T, Yamauchi T, Kita A, Takeuchi M, Kiyonaga F, Kaneko N, Sasamata M. Antitumor activity of YM155, a selective small-molecule survivin suppressant, alone and in combination with docetaxel in human malignant melanoma models. Clin Cancer Res. 2011 Aug 15; 17(16):5423-31. PMID: 21737502.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  68. Yamanaka K, Nakata M, Kaneko N, Fushiki H, Kita A, Nakahara T, Koutoku H, Sasamata M. YM155, a selective survivin suppressant, inhibits tumor spread and prolongs survival in a spontaneous metastatic model of human triple negative breast cancer. Int J Oncol. 2011 Sep; 39(3):569-75. PMID: 21674125.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  69. Watanabe M, Takemasa I, Kaneko N, Yokoyama Y, Matsuo E, Iwasa S, Mori M, Matsuura N, Monden M, Nishimura O. Clinical significance of circulating galectins as colorectal cancer markers. Oncol Rep. 2011 May; 25(5):1217-26. PMID: 21369702.
    Citations: 27     Fields:    Translation:Humans
  70. Kaneko N, Itoh K, Sugiyama A, Izumi Y. Microminipig, a non-rodent experimental animal optimized for life science research: preface. J Pharmacol Sci. 2011; 115(2):112-4. PMID: 21258171.
    Citations: 21     Fields:    Translation:Animals
  71. Sugiyama A, Nakamura Y, Akie Y, Saito H, Izumi Y, Yamazaki H, Kaneko N, Itoh K. Microminipig, a non-rodent experimental animal optimized for life science research: in vivo proarrhythmia models of drug-induced long QT syndrome: development of chronic atrioventricular block model of microminipig. J Pharmacol Sci. 2011; 115(2):122-6. PMID: 21258169.
    Citations: 7     Fields:    Translation:Animals
  72. Kita A, Nakahara T, Yamanaka K, Nakano K, Nakata M, Mori M, Kaneko N, Koutoku H, Izumisawa N, Sasamata M. Antitumor effects of YM155, a novel survivin suppressant, against human aggressive non-Hodgkin lymphoma. Leuk Res. 2011 Jun; 35(6):787-92. PMID: 21237508.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  73. Capon DJ, Kaneko N, Yoshimori T, Shimada T, Wurm FM, Hwang PK, Tong X, Adams SA, Simmons G, Sato TA, Tanaka K. Flexible antibodies with nonprotein hinges. Proc Jpn Acad Ser B Phys Biol Sci. 2011; 87(9):603-16. PMID: 22075761.
    Citations: 1     Fields:    Translation:HumansCells
  74. Hirai H, Iwasawa Y, Okada M, Arai T, Nishibata T, Kobayashi M, Kimura T, Kaneko N, Ohtani J, Yamanaka K, Itadani H, Takahashi-Suzuki I, Fukasawa K, Oki H, Nambu T, Jiang J, Sakai T, Arakawa H, Sakamoto T, Sagara T, Yoshizumi T, Mizuarai S, Kotani H. Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents. Mol Cancer Ther. 2009 Nov; 8(11):2992-3000. PMID: 19887545.
    Citations: 235     Fields:    Translation:HumansAnimalsCells
  75. Hiraoka H, Minami K, Kaneko N, Shimokawa Miyama T, Okamura Y, Mizuno T, Okuda M. Aberrations of the FHIT gene and Fhit protein in canine lymphoma cell lines. J Vet Med Sci. 2009 Jun; 71(6):769-77. PMID: 19578286.
    Citations: 6     Fields:    Translation:AnimalsCells
  76. Hiraoka H, Minami K, Kaneko N, Shimokawa Miyama T, Mizuno T, Okuda M. Molecular cloning of the canine fragile histidine triad (FHIT) gene and Fhit protein expression in canine peripheral blood mononuclear cells. J Vet Med Sci. 2009 May; 71(5):645-9. PMID: 19498293.
    Citations: 2     Fields:    Translation:AnimalsCells
  77. Kaneko N, Yamamoto Y, Wada Y, Shimokawa Miyama T, Hiraoka H, Itamoto K, Mizuno T, Nakaichi M, Takahashi T, Watari T, Okuda M. Application of polymerase chain reaction to analysis of antigen receptor rearrangements to support endoscopic diagnosis of canine alimentary lymphoma. J Vet Med Sci. 2009 May; 71(5):555-9. PMID: 19498279.
    Citations: 3     Fields:    Translation:Animals
  78. Kaneko N, Tanimoto T, Morimoto M, Hayashi T, Shimokawa Miyama T, Hiraoka H, Itamoto K, Une S, Mizuno T, Okuda M. Use of formalin-fixed paraffin-embedded tissue and single-strand conformation polymorphism analysis for polymerase chain reaction of antigen receptor rearrangements in dogs. J Vet Med Sci. 2009 Apr; 71(4):535-8. PMID: 19420864.
    Citations: 1     Fields:    Translation:Animals
  79. Murayama N, Kaneko N, Horiuchi K, Ohyama K, Shimizu M, Ito K, Yamazaki H. Cytochrome P450-dependent drug oxidation activity of liver microsomes from Microminipigs, a possible new animal model for humans in non-clinical studies. Drug Metab Pharmacokinet. 2009; 24(4):404-8. PMID: 19745566.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  80. Okamura N, Masuda T, Gotoh A, Shirakawa T, Terao S, Kaneko N, Suganuma K, Watanabe M, Matsubara T, Seto R, Matsumoto J, Kawakami M, Yamamori M, Nakamura T, Yagami T, Sakaeda T, Fujisawa M, Nishimura O, Okumura K. Quantitative proteomic analysis to discover potential diagnostic markers and therapeutic targets in human renal cell carcinoma. Proteomics. 2008 Aug; 8(15):3194-203. PMID: 18615424.
    Citations: 15     Fields:    Translation:Humans
  81. Suzuki G, Kimura T, Satow A, Kaneko N, Fukuda J, Hikichi H, Sakai N, Maehara S, Kawagoe-Takaki H, Hata M, Azuma T, Ito S, Kawamoto H, Ohta H. Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC). J Pharmacol Exp Ther. 2007 Jun; 321(3):1144-53. PMID: 17360958.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  82. Oikawa T, Okuda M, Kaneko N, Watanabe M, Hiraoka H, Itamoto K, Nakaichi M, Mizuno T, Inokuma H. Cloning of the feline GADD45 cDNA and analysis of its mutation in feline lymphoma cell lines. J Vet Med Sci. 2006 Mar; 68(3):297-301. PMID: 16598179.
    Citations: 1     Fields:    Translation:AnimalsCells
  83. Nakamura C, Inuyama Y, Goto H, Obataya I, Kaneko N, Nakamura N, Santo N, Miyake J. Dioxin-binding pentapeptide for use in a high-sensitivity on-bead detection assay. Anal Chem. 2005 Dec 01; 77(23):7750-7. PMID: 16316185.
    Citations: 4     Fields:    Translation:Cells
  84. Watanabe M, Oikawa T, Hiraoka H, Kaneko N, Itamoto K, Mizuno T, Okuda M, Inokuma H. Experimental inoculation of beagle dogs with Ehrlichia species detected from Ixodes ovatus. Vet Parasitol. 2006 Mar 15; 136(2):147-54. PMID: 16309840.
    Citations: 1     Fields:    Translation:AnimalsCellsPHPublic Health
  85. Nagahara Y, Shinomiya T, Kuroda S, Kaneko N, Nishio R, Ikekita M. Phytosphingosine induced mitochondria-involved apoptosis. Cancer Sci. 2005 Feb; 96(2):83-92. PMID: 15723652.
    Citations: 9     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.