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Salim S. Abdool Karim, Ph.D., M.Med., M.B.,Ch.B.
Title
Adjunct Professor of Immunology and Infectious Diseases
Institution
Harvard T.H. Chan School of Public Health
Department
Immunology and Infectious Diseases
Address
Harvard T.H. Chan School of Public Health
SPH 1 RM 806
665 Huntington Ave
Boston MA 02115
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research activities and funding
|
selected publications
|
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
U2GPS001350
(ABDOOL KARIM, SALIM S)
Sep 30, 2008 - Sep 29, 2014
NIH
CAPRISA AIDS TREATMENT PROGRAMME
Role: Principal Investigator
U01AI069469
(ABDOOL KARIM, SALIM S)
Mar 1, 2007 - Jan 31, 2014
NIH
University of KwaZulu-Natal - CAPRISA HIV/AIDS Clinical Trials Unit
Role: Principal Investigator
UM1AI069469
(ABDOOL KARIM, QUARRAISHA)
Mar 1, 2007 - Dec 9, 2013
NIH
KwaZulu-Natal Clinical Trials Unit
Role: Principal Investigator
R21TW006111
(ABDOOL KARIM, SALIM S)
Sep 22, 2002 - Sep 21, 2003
NIH
Natal-Columbia Clinical AIDS/TB Training Program
Role: Principal Investigator
U19AI051794
(ABDOOL KARIM, SALIM S)
Jul 1, 2002 - Jun 30, 2008
NIH
COLLABORATIVE AIDS PROGRAMME OF RESEARCH IN SOUTH AFRICA
Role: Principal Investigator
U01AI048008
(RAMJEE, GITA)
Jul 1, 2000 - Jun 30, 2005
NIH
SOUTH AFRICA MRC HIV PREVENTION TRIALS UNIT
Role: Co-Principal Investigator
U01AI048013
(GRAY, GLENDA E)
Jul 1, 2000 - Nov 30, 2004
NIH
SOUTHERN AFRICA-NEW YORK HIV VACCINE TRIALS UNIT
Role: Co-Principal Investigator
D43TW000231
(ABDOOL KARIM, QUARRAISHA)
Jun 1, 1993 - Oct 31, 2015
NIH
Columbia University-Southern African AIDS International Training/Research Program
Role: Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Garrett N, Mtshali A, Osman F, Masson L, McKinnon LR, Singh R, Mitchev N, Ngobese H, Kharsany ABM, Abdool Karim S, Mlisana K, Passmore JA, Rompalo A, Mindel A, Liebenberg L. Impact of point-of-care testing and treatment of sexually transmitted infections and bacterial vaginosis on genital tract inflammatory cytokines in a cohort of young South African women. Sex Transm Infect. 2021 Feb 19.
PMID:
33608480
.
Citations:
Fields:
Sex
Sexually Transmitted Diseases
Mahomed S, Garrett N, Baxter C, Abdool Karim Q, Abdool Karim SS. Clinical Trials of Broadly Neutralizing Monoclonal Antibodies for Human Immunodeficiency Virus Prevention: A Review. J Infect Dis. 2021 Feb 13; 223(3):370-380.
PMID:
32604408
.
Citations:
1
Fields:
Com
Communicable Diseases
Mahomed S, Garrett N, Karim QA, Zuma NY, Capparelli E, Baxter C, Gengiah T, Archary D, Samsunder N, Rose ND, Moore P, Williamson C, Barouch DH, Fast PE, Pozzetto B, Hankins C, Carlton K, Ledgerwood J, Morris L, Mascola J, Abdool Karim S. Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial. BMJ Open. 2020 11 26; 10(11):e042247.
PMID:
33243815
.
Citations:
Fields:
Med
Medicine (General)
Scheepers C, Bekker V, Anthony C, Richardson SI, Oosthuysen B, Moyo T, Kgagudi P, Kitchin D, Nonyane M, York T, Mielke D, Mabvakure BM, Sheng Z, Lambson BE, Ismail A, Garrett NJ, Abdool Karim SS, Shapiro L, Williamson C, Morris L, Moore PL. Antibody Isotype Switching as a Mechanism to Counter HIV Neutralization Escape. Cell Rep. 2020 Nov 24; 33(8):108430.
PMID:
33238131
.
Citations:
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Baxter C, Abdool Karim Q, Abdool Karim SS. Identifying SARS-CoV-2 infections in South Africa: Balancing public health imperatives with saving lives. Biochem Biophys Res Commun. 2021 01 29; 538:221-225.
PMID:
33143875
.
Citations:
Fields:
Bio
Biochemistry
Bio
Biophysics
Cromarty R, Sigal A, Liebenberg LJ, Mckinnon LR, Abdool Karim SS, Passmore JS, Archary D. Betamethasone induces potent immunosuppression and reduces HIV infection in a PBMC in vitro model. J Investig Med. 2021 Jan; 69(1):28-40.
PMID:
33004468
.
Citations:
1
Fields:
Med
Medicine (General)
Brault MA, Spiegelman D, Abdool Karim SS, Vermund SH. Correction to: Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials. Curr HIV/AIDS Rep. 2020 Oct; 17(5):577.
PMID:
32601917
.
Citations:
Fields:
Acq
Acquired Immunodeficiency Synd
Abdool Karim Q, Abdool Karim SS. COVID-19 affects HIV and tuberculosis care. Science. 2020 07 24; 369(6502):366-368.
PMID:
32703860
.
Citations:
5
Fields:
Sci
Science
Translation:
Humans
PH
Public Health
Fisher KL, Mabuka JM, Sivro A, Ngcapu S, Passmore JS, Osman F, Ndlovu B, Abdool Karim Q, Abdool Karim SS, Chung AW, Baxter C, Archary D. Topical Tenofovir Pre-exposure Prophylaxis and Mucosal HIV-Specific Fc-Mediated Antibody Activities in Women. Front Immunol. 2020; 11:1274.
PMID:
32733445
.
Citations:
Fields:
All
Allergy and Immunology
Brault MA, Spiegelman D, Abdool Karim SS, Vermund SH. Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials. Curr HIV/AIDS Rep. 2020 06; 17(3):249-258.
PMID:
32297219
.
Citations:
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
PH
Public Health
Abdool Karim SS. The South African Response to the Pandemic. N Engl J Med. 2020 06 11; 382(24):e95.
PMID:
32469479
.
Citations:
14
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
PH
Public Health
Abdool Karim S. Criminalisation of transmission of SARS-CoV-2: A potential challenge to controlling the outbreak in South Africa. S Afr Med J. 2020 04 22; 110(6):458-460.
PMID:
32880551
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
PH
Public Health
Drain PK, Dorward J, Violette LR, Quame-Amaglo J, Thomas KK, Samsunder N, Ngobese H, Mlisana K, Moodley P, Donnell D, Barnabas RV, Naidoo K, Abdool Karim SS, Celum C, Garrett N. Point-of-care HIV viral load testing combined with task shifting to improve treatment outcomes (STREAM): findings from an open-label, non-inferiority, randomised controlled trial. Lancet HIV. 2020 04; 7(4):e229-e237.
PMID:
32105625
.
Citations:
11
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Cells
Molatlhegi RP, Liebenberg LJ, Leslie A, Noel-Romas L, Mabhula A, Mchunu N, Perner M, Birse K, Ngcapu S, Adamson JH, Govender K, Garrett NJ, Samsunder N, Burgener AD, Abdool Karim SS, Abdool Karim Q, Passmore JS, McKinnon LR. Plasma concentration of injectable contraceptive correlates with reduced cervicovaginal growth factor expression in South African women. Mucosal Immunol. 2020 05; 13(3):449-459.
PMID:
31896762
.
Citations:
1
Fields:
All
Allergy and Immunology
Richardson SI, Lambson BE, Crowley AR, Bashirova A, Scheepers C, Garrett N, Abdool Karim S, Mkhize NN, Carrington M, Ackerman ME, Moore PL, Morris L. IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody. PLoS Pathog. 2019 12; 15(12):e1008064.
PMID:
31841557
.
Citations:
7
Fields:
Mic
Microbiology
Translation:
Humans
Mielke D, Bandawe G, Pollara J, Abrahams MR, Nyanhete T, Moore PL, Thebus R, Yates NL, Kappes JC, Ochsenbauer C, Garrett N, Abdool Karim S, Tomaras GD, Montefiori D, Morris L, Ferrari G, Williamson C. Antibody-Dependent Cellular Cytotoxicity (ADCC)-Mediating Antibodies Constrain Neutralizing Antibody Escape Pathway. Front Immunol. 2019; 10:2875.
PMID:
31921139
.
Citations:
4
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Liebenberg LJP, McKinnon LR, Yende-Zuma N, Garrett N, Baxter C, Kharsany ABM, Archary D, Rositch A, Samsunder N, Mansoor LE, Passmore JS, Abdool Karim SS, Abdool Karim Q. HPV infection and the genital cytokine milieu in women at high risk of HIV acquisition. Nat Commun. 2019 11 19; 10(1):5227.
PMID:
31745084
.
Citations:
3
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Kharsany ABM, Cawood C, Lewis L, Yende-Zuma N, Khanyile D, Puren A, Madurai S, Baxter C, George G, Govender K, Beckett S, Samsunder N, Toledo C, Ayalew KA, Diallo K, Glenshaw M, Herman-Roloff A, Wilkinson E, de Oliveira T, Abdool Karim SS, Abdool Karim Q. Trends in HIV Prevention, Treatment, and Incidence in a Hyperendemic Area of KwaZulu-Natal, South Africa. JAMA Netw Open. 2019 11 01; 2(11):e1914378.
PMID:
31675082
.
Citations:
3
Fields:
Med
Medicine (General)
Translation:
Humans
PH
Public Health
Mwatelah R, McKinnon LR, Baxter C, Abdool Karim Q, Abdool Karim SS. Mechanisms of sexually transmitted infection-induced inflammation in women: implications for HIV risk. J Int AIDS Soc. 2019 08; 22 Suppl 6:e25346.
PMID:
31468677
.
Citations:
4
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Cromarty R, Sigal A, Liebenberg LJP, McKinnon LR, Abdool Karim SS, Passmore JS, Archary D. Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated in vitro Model. Front Immunol. 2019; 10:1705.
PMID:
31396221
.
Citations:
4
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Abdool Karim SS. HIV-1 Epidemic Control - Insights from Test-and-Treat Trials. N Engl J Med. 2019 07 18; 381(3):286-288.
PMID:
31314975
.
Citations:
18
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
PH
Public Health
Mahomed S, Garrett N, Capparelli E, Baxter C, Zuma NY, Gengiah T, Archary D, Moore P, Samsunder N, Barouch DH, Mascola J, Ledgerwood J, Morris L, Abdool Karim S. Assessing the safety and pharmacokinetics of the monoclonal antibodies, VRC07-523LS and PGT121 in HIV negative women in South Africa: study protocol for the CAPRISA 012A randomised controlled phase I trial. BMJ Open. 2019 07 03; 9(7):e030283.
PMID:
31272988
.
Citations:
3
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Baxter C, Ngcapu S, Blackard JT, Powell EA, Penton PK, Abdool Karim SS. Frequency of Hepatitis B Virus Resistance Mutations in Women Using Tenofovir Gel as Pre-Exposure Prophylaxis. Viruses. 2019 06 19; 11(6).
PMID:
31248149
.
Citations:
Fields:
Vir
Virology
Translation:
Humans
Cells
PH
Public Health
Naidoo K, Gengiah S, Yende-Zuma N, Padayatchi N, Barker P, Nunn A, Subrayen P, Abdool Karim SS. Correction to: Addressing challenges in scaling up TB and HIV treatment integration in rural primary healthcare clinics in South Africa (SUTHI): a cluster randomized controlled trial protocol. Implement Sci. 2019 06 13; 14(1):59.
PMID:
31196142
.
Citations:
Fields:
Hea
Health Services Research
van den Berg FT, Makoah NA, Ali SA, Scott TA, Mapengo RE, Mutsvunguma LZ, Mkhize NN, Lambson BE, Kgagudi PD, Crowther C, Abdool Karim SS, Balazs AB, Weinberg MS, Ely A, Arbuthnot PB, Morris L. AAV-Mediated Expression of Broadly Neutralizing and Vaccine-like Antibodies Targeting the HIV-1 Envelope V2 Region. Mol Ther Methods Clin Dev. 2019 Sep 13; 14:100-112.
PMID:
31334303
.
Citations:
9
Mabvakure BM, Lambson BE, Ramdayal K, Masson L, Kitchin D, Allam M, Abdool Karim S, Williamson C, Passmore JA, Martin DP, Scheepers C, Moore PL, Harkins GW, Morris L. Evidence for both Intermittent and Persistent Compartmentalization of HIV-1 in the Female Genital Tract. J Virol. 2019 05 15; 93(10).
PMID:
30842323
.
Citations:
Fields:
Vir
Virology
Translation:
Humans
Cells
Abdool Karim SS, Baxter C, Passmore JS, McKinnon LR, Williams BL. The genital tract and rectal microbiomes: their role in HIV susceptibility and prevention in women. J Int AIDS Soc. 2019 05; 22(5):e25300.
PMID:
31144462
.
Citations:
7
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Cells
Chimukangara B, Lessells RJ, Rhee SY, Giandhari J, Kharsany ABM, Naidoo K, Lewis L, Cawood C, Khanyile D, Ayalew KA, Diallo K, Samuel R, Hunt G, Vandormael A, Stray-Pedersen B, Gordon M, Makadzange T, Kiepiela P, Ramjee G, Ledwaba J, Kalimashe M, Morris L, Parikh UM, Mellors JW, Shafer RW, Katzenstein D, Moodley P, Gupta RK, Pillay D, Abdool Karim SS, de Oliveira T. Trends in Pretreatment HIV-1 Drug Resistance in Antiretroviral Therapy-naive Adults in South Africa, 2000-2016: A Pooled Sequence Analysis. EClinicalMedicine. 2019 Mar; 9:26-34.
PMID:
31143879
.
Citations:
14
Mabvakure BM, Scheepers C, Garrett N, Abdool Karim S, Williamson C, Morris L, Moore PL. Positive Selection at Key Residues in the HIV Envelope Distinguishes Broad and Strain-Specific Plasma Neutralizing Antibodies. J Virol. 2019 03 15; 93(6).
PMID:
30567996
.
Citations:
2
Fields:
Vir
Virology
Translation:
Humans
Cells
PH
Public Health
Johnson EL, Doria-Rose NA, Gorman J, Bhiman JN, Schramm CA, Vu AQ, Law WH, Zhang B, Bekker V, Abdool Karim SS, Ippolito GC, Morris L, Moore PL, Kwong PD, Mascola JR, Georgiou G. Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation. Nat Commun. 2018 10 08; 9(1):4136.
PMID:
30297708
.
Citations:
4
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Sheward DJ, Marais J, Bekker V, Murrell B, Eren K, Bhiman JN, Nonyane M, Garrett N, Woodman ZL, Abdool Karim Q, Abdool Karim SS, Morris L, Moore PL, Williamson C. HIV Superinfection Drives De Novo Antibody Responses and Not Neutralization Breadth. . 2018 10 10; 24(4):593-599.e3.
PMID:
30269971
.
Citations:
6
Translation:
Humans
Cells
Joag V, Sivro A, Yende-Zuma N, Imam H, Samsunder N, Abdool Karim Q, Abdool Karim S, McKinnon L, Kaul R. Ex vivo HIV entry into blood CD4+ T cells does not predict heterosexual HIV acquisition in women. PLoS One. 2018; 13(7):e0200359.
PMID:
29985942
.
Citations:
3
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Barré-Sinoussi F, Abdool Karim SS, Albert J, Bekker LG, Beyrer C, Cahn P, Calmy A, Grinsztejn B, Grulich A, Kamarulzaman A, Kumarasamy N, Loutfy MR, El Filali KM, Mboup S, Montaner JS, Munderi P, Pokrovsky V, Vandamme AM, Young B, Godfrey-Faussett P. Expert consensus statement on the science of HIV in the context of criminal law. J Int AIDS Soc. 2018 07; 21(7):e25161.
PMID:
30044059
.
Citations:
9
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Abdool Karim Q, Abdool Karim SS. HIV-No time for complacency. Science. 2018 06 15; 360(6394):1153.
PMID:
29903942
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Cells
PH
Public Health
Tanko RF, Soares AP, Masson L, Garrett NJ, Samsunder N, Abdool Karim Q, Abdool Karim SS, Riou C, Burgers WA. Residual T cell activation and skewed CD8+ T cell memory differentiation despite antiretroviral therapy-induced HIV suppression. Clin Immunol. 2018 10; 195:127-138.
PMID:
29883708
.
Citations:
11
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Dorward J, Lessells R, Drain PK, Naidoo K, de Oliveira T, Pillay Y, Abdool Karim SS, Garrett N. Dolutegravir for first-line antiretroviral therapy in low-income and middle-income countries: uncertainties and opportunities for implementation and research. Lancet HIV. 2018 07; 5(7):e400-e404.
PMID:
29884404
.
Citations:
15
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Cells
Garrett NJ, Osman F, Maharaj B, Naicker N, Gibbs A, Norman E, Samsunder N, Ngobese H, Mitchev N, Singh R, Abdool Karim SS, Kharsany ABM, Mlisana K, Rompalo A, Mindel A. Beyond syndromic management: Opportunities for diagnosis-based treatment of sexually transmitted infections in low- and middle-income countries. PLoS One. 2018; 13(4):e0196209.
PMID:
29689080
.
Citations:
11
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Anthony C, York T, Bekker V, Matten D, Selhorst P, Ferreria RC, Garrett NJ, Abdool Karim SS, Morris L, Wood NT, Moore PL, Williamson C. Correction for Anthony et al., "Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope". J Virol. 2018 05 01; 92(9).
PMID:
29654221
.
Citations:
Fields:
Vir
Virology
Richardson SI, Chung AW, Natarajan H, Mabvakure B, Mkhize NN, Garrett N, Abdool Karim S, Moore PL, Ackerman ME, Alter G, Morris L. HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies. PLoS Pathog. 2018 04; 14(4):e1006987.
PMID:
29630668
.
Citations:
19
Fields:
Mic
Microbiology
Translation:
Humans
Cells
Moosa Y, Tanko RF, Ramsuran V, Singh R, Madzivhandila M, Yende-Zuma N, Abrahams MR, Selhorst P, Gounder K, Moore PL, Williamson C, Abdool Karim SS, Garrett NJ, Burgers WA. Case report: mechanisms of HIV elite control in two African women. BMC Infect Dis. 2018 01 25; 18(1):54.
PMID:
29370775
.
Citations:
4
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Sivro A, Schuetz A, Sheward D, Joag V, Yegorov S, Liebenberg LJ, Yende-Zuma N, Stalker A, Mwatelah RS, Selhorst P, Garrett N, Samsunder N, Balgobin A, Nawaz F, Cicala C, Arthos J, Fauci AS, Anzala AO, Kimani J, Bagaya BS, Kiwanuka N, Williamson C, Kaul R, Passmore JS, Phanuphak N, Ananworanich J, Ansari A, Abdool Karim Q, Abdool Karim SS, McKinnon LR. Integrin a4ß7 expression on peripheral blood CD4+ T cells predicts HIV acquisition and disease progression outcomes. Sci Transl Med. 2018 01 24; 10(425).
PMID:
29367348
.
Citations:
25
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Abdool Karim SS, Passmore JS, Baxter C. The microbiome and HIV prevention strategies in women. Curr Opin HIV AIDS. 2018 Jan; 13(1):81-87.
PMID:
29059077
.
Citations:
2
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Cells
PH
Public Health
Naidoo K, Gengiah S, Yende-Zuma N, Padayatchi N, Barker P, Nunn A, Subrayen P, Abdool Karim SS. Addressing challenges in scaling up TB and HIV treatment integration in rural primary healthcare clinics in South Africa (SUTHI): a cluster randomized controlled trial protocol. Implement Sci. 2017 Nov 13; 12(1):129.
PMID:
29132380
.
Citations:
7
Fields:
Hea
Health Services Research
Translation:
Humans
Scheepers C, Chowdhury S, Wright WS, Campbell CT, Garrett NJ, Abdool Karim Q, Abdool Karim SS, Moore PL, Gildersleeve JC, Morris L. Serum glycan-binding IgG antibodies in HIV-1 infection and during the development of broadly neutralizing responses. AIDS. 2017 10 23; 31(16):2199-2209.
PMID:
28926408
.
Citations:
3
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Cells
Dorward J, Garrett N, Quame-Amaglo J, Samsunder N, Ngobese H, Ngomane N, Moodley P, Mlisana K, Schaafsma T, Donnell D, Barnabas R, Naidoo K, Abdool Karim S, Celum C, Drain PK. Protocol for a randomised controlled implementation trial of point-of-care viral load testing and task shifting: the Simplifying HIV TREAtment and Monitoring (STREAM) study. BMJ Open. 2017 Sep 27; 7(9):e017507.
PMID:
28963304
.
Citations:
11
Fields:
Med
Medicine (General)
Translation:
Humans
Julg B, Tartaglia LJ, Keele BF, Wagh K, Pegu A, Sok D, Abbink P, Schmidt SD, Wang K, Chen X, Joyce MG, Georgiev IS, Choe M, Kwong PD, Doria-Rose NA, Le K, Louder MK, Bailer RT, Moore PL, Korber B, Seaman MS, Abdool Karim SS, Morris L, Koup RA, Mascola JR, Burton DR, Barouch DH. Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge. Sci Transl Med. 2017 09 06; 9(406).
PMID:
28878010
.
Citations:
37
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Animals
Cells
Ngandu NK, Carlson JM, Chopera DR, Ndabambi N, Abdool Karim Q, Abdool Karim S, Williamson C. Brief Report: Selection of HIV-1 Variants With Higher Transmission Potential by 1% Tenofovir Gel Microbicide. . 2017 09 01; 76(1):43-47.
PMID:
28797020
.
Citations:
1
Translation:
Humans
Cells
PH
Public Health
Sivro A, McKinnon LR, Yende-Zuma N, Gengiah S, Samsunder N, Abdool Karim SS, Naidoo K. Plasma Cytokine Predictors of Tuberculosis Recurrence in Antiretroviral-Treated Human Immunodeficiency Virus-infected Individuals from Durban, South Africa. Clin Infect Dis. 2017 Sep 01; 65(5):819-826.
PMID:
29017282
.
Citations:
3
Fields:
Com
Communicable Diseases
Translation:
Humans
Klatt NR, Cheu R, Birse K, Zevin AS, Perner M, Noël-Romas L, Grobler A, Westmacott G, Xie IY, Butler J, Mansoor L, McKinnon LR, Passmore JS, Abdool Karim Q, Abdool Karim SS, Burgener AD. Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women. Science. 2017 06 02; 356(6341):938-945.
PMID:
28572388
.
Citations:
113
Fields:
Sci
Science
Translation:
Humans
Cells
Selhorst P, Combrinck C, Ndabambi N, Ismail SD, Abrahams MR, Lacerda M, Samsunder N, Garrett N, Abdool Karim Q, Abdool Karim SS, Williamson C. Replication Capacity of Viruses from Acute Infection Drives HIV-1 Disease Progression. J Virol. 2017 04 15; 91(8).
PMID:
28148791
.
Citations:
4
Fields:
Vir
Virology
Translation:
Humans
Cells
Mabvakure B, Scheepers C, Nonyane M, Lambson B, Madzorera S, Kitchin D, Bhiman J, Wibmer K, Abdool Karim S, Williamson C, Morris L, Moore PL. A38 Diversity analyses of HIV-1 envelope glycoproteins in HIV-infected individuals with and without broadly neutralizing antibodies. Virus Evol. 2017 Mar; 3(Suppl 1).
PMID:
28845277
.
Citations:
Liebenberg LJ, Masson L, Arnold KB, Mckinnon LR, Werner L, Proctor E, Archary D, Mansoor LE, Lauffenburger DA, Abdool Karim Q, Abdool Karim SS, Passmore JS. Genital-Systemic Chemokine Gradients and the Risk of HIV Acquisition in Women. . 2017 Mar 01; 74(3):318-325.
PMID:
28187085
.
Citations:
14
Translation:
Humans
Chopera DR, Ntale R, Ndabambi N, Garrett N, Gray CM, Matten D, Abdool Karim Q, Abdool Karim S, Williamson C. Early evolution of human leucocyte antigen-associated escape mutations in variable Gag proteins predicts CD4+ decline in HIV-1 subtype C-infected women. AIDS. 2017 01 14; 31(2):191-197.
PMID:
27755110
.
Citations:
1
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Cells
Wibmer CK, Gorman J, Ozorowski G, Bhiman JN, Sheward DJ, Elliott DH, Rouelle J, Smira A, Joyce MG, Ndabambi N, Druz A, Asokan M, Burton DR, Connors M, Abdool Karim SS, Mascola JR, Robinson JE, Ward AB, Williamson C, Kwong PD, Morris L, Moore PL. Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape. PLoS Pathog. 2017 01; 13(1):e1006074.
PMID:
28076415
.
Citations:
15
Fields:
Mic
Microbiology
Translation:
Humans
Cells
Doria-Rose NA, Altae-Tran HR, Roark RS, Schmidt SD, Sutton MS, Louder MK, Chuang GY, Bailer RT, Cortez V, Kong R, McKee K, O'Dell S, Wang F, Abdool Karim SS, Binley JM, Connors M, Haynes BF, Martin MA, Montefiori DC, Morris L, Overbaugh J, Kwong PD, Mascola JR, Georgiev IS. Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting. PLoS Pathog. 2017 01; 13(1):e1006148.
PMID:
28052137
.
Citations:
21
Fields:
Mic
Microbiology
Translation:
Humans
Cells
Tanko RF, Soares AP, Müller TL, Garrett NJ, Samsunder N, Abdool Karim Q, Abdool Karim SS, Riou C, Burgers WA. Effect of Antiretroviral Therapy on the Memory and Activation Profiles of B Cells in HIV-Infected African Women. J Immunol. 2017 02 01; 198(3):1220-1228.
PMID:
28039305
.
Citations:
6
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Sobieszczyk ME, Werner L, Mlisana K, Naicker N, Feinstein A, Gray CM, Masson L, Passmore JS, Williamson C, Abdool Karim Q, Abdool Karim SS, Garrett NJ. Metabolic Syndrome After HIV Acquisition in South African Women. . 2016 Dec 01; 73(4):438-445.
PMID:
27391387
.
Citations:
10
Translation:
Humans
Wibmer CK, Gorman J, Anthony CS, Mkhize NN, Druz A, York T, Schmidt SD, Labuschagne P, Louder MK, Bailer RT, Abdool Karim SS, Mascola JR, Williamson C, Moore PL, Kwong PD, Morris L. Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site. J Virol. 2016 Nov 15; 90(22):10220-10235.
PMID:
27581986
.
Citations:
14
Fields:
Vir
Virology
Translation:
Humans
Cells
Selhorst P, Masson L, Ismail SD, Samsunder N, Garrett N, Mansoor LE, Abdool Karim Q, Abdool Karim SS, Passmore JS, Williamson C. Cervicovaginal Inflammation Facilitates Acquisition of Less Infectious HIV Variants. Clin Infect Dis. 2017 Jan 01; 64(1):79-82.
PMID:
27694480
.
Citations:
20
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Madlala P, Singh R, An P, Werner L, Mlisana K, Abdool Karim SS, Winkler CA, Ndung'u T. Association of Polymorphisms in the Regulatory Region of the Cyclophilin a Gene (PPIA) with Gene Expression and HIV/AIDS Disease Progression. . 2016 08 15; 72(5):465-73.
PMID:
27088296
.
Citations:
1
Translation:
Humans
Cells
Rademeyer C, Korber B, Seaman MS, Giorgi EE, Thebus R, Robles A, Sheward DJ, Wagh K, Garrity J, Carey BR, Gao H, Greene KM, Tang H, Bandawe GP, Marais JC, Diphoko TE, Hraber P, Tumba N, Moore PL, Gray GE, Kublin J, McElrath MJ, Vermeulen M, Middelkoop K, Bekker LG, Hoelscher M, Maboko L, Makhema J, Robb ML, Abdool Karim S, Abdool Karim Q, Kim JH, Hahn BH, Gao F, Swanstrom R, Morris L, Montefiori DC, Williamson C. Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization. PLoS Pathog. 2016 07; 12(7):e1005742.
PMID:
27434311
.
Citations:
29
Fields:
Mic
Microbiology
Translation:
Humans
Cells
PH
Public Health
Baxter C, Abdool Karim S. Combination HIV prevention options for young women in Africa. Afr J AIDS Res. 2016 Jul; 15(2):109-21.
PMID:
27399041
.
Citations:
9
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
PH
Public Health
Garrett NJ, Drain PK, Werner L, Samsunder N, Abdool Karim SS. Diagnostic Accuracy of the Point-of-Care Xpert HIV-1 Viral Load Assay in a South African HIV Clinic. . 2016 06 01; 72(2):e45-8.
PMID:
26959192
.
Citations:
19
Translation:
Humans
Cells
Shey MS, Maharaj N, Archary D, Ngcapu S, Garrett N, Abdool Karim S, Passmore JA. Modulation of Female Genital Tract-Derived Dendritic Cell Migration and Activation in Response to Inflammatory Cytokines and Toll-Like Receptor Agonists. PLoS One. 2016; 11(5):e0155668.
PMID:
27171482
.
Citations:
2
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Archary D, Seaton KE, Passmore JS, Werner L, Deal A, Dunphy LJ, Arnold KB, Yates NL, Lauffenburger DA, Bergin P, Liebenberg LJ, Samsunder N, Mureithi MW, Altfeld M, Garrett N, Abdool Karim Q, Abdool Karim SS, Morris L, Tomaras GD. Distinct genital tract HIV-specific antibody profiles associated with tenofovir gel. Mucosal Immunol. 2016 05; 9(3):834.
PMID:
27116933
.
Citations:
Fields:
All
Allergy and Immunology
Balkus JE, Brown ER, Hillier SL, Coletti A, Ramjee G, Mgodi N, Makanani B, Reid C, Martinson F, Soto-Torres L, Abdool Karim SS, Chirenje ZM. Corrigendum to "oral and injectable contraceptive use and HIV acquisition risk among women in four African countries: a secondary analysis of data from a microbicide trial" [Contraception 2016; 93 (1): 25-31]. Contraception. 2016 Jul; 94(1):95.
PMID:
27085419
.
Citations:
1
Fields:
Rep
Reproductive Medicine
Gray GE, Laher F, Doherty T, Abdool Karim S, Hammer S, Mascola J, Beyrer C, Corey L. Which New Health Technologies Do We Need to Achieve an End to HIV/AIDS? PLoS Biol. 2016 Mar; 14(3):e1002372.
PMID:
26933962
.
Citations:
7
Fields:
Bio
Biology
Translation:
Humans
Kløverpris HN, Kazer SW, Mjösberg J, Mabuka JM, Wellmann A, Ndhlovu Z, Yadon MC, Nhamoyebonde S, Muenchhoff M, Simoni Y, Andersson F, Kuhn W, Garrett N, Burgers WA, Kamya P, Pretorius K, Dong K, Moodley A, Newell EW, Kasprowicz V, Abdool Karim SS, Goulder P, Shalek AK, Walker BD, Ndung'u T, Leslie A. Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression. Immunity. 2016 Feb 16; 44(2):391-405.
PMID:
26850658
.
Citations:
55
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Naranbhai V, de Assis Rosa D, Werner L, Moodley R, Hong H, Kharsany A, Mlisana K, Sibeko S, Garrett N, Chopera D, Carr WH, Abdool Karim Q, Hill AV, Abdool Karim SS, Altfeld M, Gray CM, Ndung'u T. Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women. BMC Infect Dis. 2016 Jan 25; 16:27.
PMID:
26809736
.
Citations:
1
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Abdool Karim SS, Abdool Karim Q, Gengiah TN. Tenofovir Gel to Prevent HSV-2 Infection. N Engl J Med. 2015 11 12; 373(20):1980-1.
PMID:
26559584
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Kharsany AB, Frohlich JA, Yende-Zuma N, Mahlase G, Samsunder N, Dellar RC, Zuma-Mkhonza M, Abdool Karim SS, Abdool Karim Q. Trends in HIV Prevalence in Pregnant Women in Rural South Africa. . 2015 Nov 01; 70(3):289-95.
PMID:
26186507
.
Citations:
16
Translation:
Humans
Masson L, Arnold KB, Little F, Mlisana K, Lewis DA, Mkhize N, Gamieldien H, Ngcapu S, Johnson L, Lauffenburger DA, Abdool Karim Q, Abdool Karim SS, Passmore JA. Inflammatory cytokine biomarkers to identify women with asymptomatic sexually transmitted infections and bacterial vaginosis who are at high risk of HIV infection. Sex Transm Infect. 2016 May; 92(3):186-93.
PMID:
26511781
.
Citations:
14
Fields:
Sex
Sexually Transmitted Diseases
Translation:
Humans
Balkus JE, Brown ER, Hillier SL, Coletti A, Ramjee G, Mgodi N, Makanani B, Reid C, Martinson F, Soto-Torres L, Abdool Karim SS, Chirenje ZM. Oral and injectable contraceptive use and HIV acquisition risk among women in four African countries: a secondary analysis of data from a microbicide trial. Contraception. 2016 Jan; 93(1):25-31.
PMID:
26519646
.
Citations:
8
Fields:
Rep
Reproductive Medicine
Translation:
Humans
Masson L, Salkinder AL, Olivier AJ, McKinnon LR, Gamieldien H, Mlisana K, Scriba TJ, Lewis DA, Little F, Jaspan HB, Ronacher K, Denny L, Abdool Karim SS, Passmore JA. Relationship between female genital tract infections, mucosal interleukin-17 production and local T helper type 17 cells. Immunology. 2015 Dec; 146(4):557-67.
PMID:
26302175
.
Citations:
17
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Gengiah TN, Botha JH, Yende-Zuma N, Naidoo K, Abdool Karim SS. Efavirenz dosing: influence of drug metabolizing enzyme polymorphisms and concurrent tuberculosis treatment. Antivir Ther. 2015; 20(3):297-306.
PMID:
25318122
.
Citations:
4
Fields:
Ant
Anti-Infective Agents
Vir
Virology
Translation:
Humans
Bhiman JN, Anthony C, Doria-Rose NA, Karimanzira O, Schramm CA, Khoza T, Kitchin D, Botha G, Gorman J, Garrett NJ, Abdool Karim SS, Shapiro L, Williamson C, Kwong PD, Mascola JR, Morris L, Moore PL. Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies. Nat Med. 2015 Nov; 21(11):1332-6.
PMID:
26457756
.
Citations:
102
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Cells
Naidoo K, Grobler AC, Deghaye N, Reddy T, Gengiah S, Gray A, Abdool Karim S. Cost-Effectiveness of Initiating Antiretroviral Therapy at Different Points in TB Treatment in HIV-TB Coinfected Ambulatory Patients in South Africa. . 2015 Aug 15; 69(5):576-84.
PMID:
26167618
.
Citations:
4
Translation:
Humans
Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK. Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor. Proc Natl Acad Sci U S A. 2015 Aug 25; 112(34):E4762-71.
PMID:
26307764
.
Citations:
16
Fields:
Sci
Science
Translation:
Humans
Cells
Abdool Karim SS, Abdool Karim Q, Kharsany AB, Baxter C, Grobler AC, Werner L, Kashuba A, Mansoor LE, Samsunder N, Mindel A, Gengiah TN. Tenofovir Gel for the Prevention of Herpes Simplex Virus Type 2 Infection. N Engl J Med. 2015 Aug 06; 373(6):530-9.
PMID:
26244306
.
Citations:
27
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Abdool Karim SS. Overcoming Impediments to Global Implementation of Early Antiretroviral Therapy. N Engl J Med. 2015 Aug 27; 373(9):875-6.
PMID:
26193047
.
Citations:
14
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Pellett Madan R, Masson L, Tugetman J, Werner L, Grobler A, Mlisana K, Lo Y, Che D, Arnold KB, Abdool Karim SS, Passmore JA, Herold BC. Innate Antibacterial Activity in Female Genital Tract Secretions Is Associated with Increased Risk of HIV Acquisition. AIDS Res Hum Retroviruses. 2015 Nov; 31(11):1153-9.
PMID:
26061218
.
Citations:
8
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Cells
Archary D, Liebenberg LJ, Werner L, Tulsi S, Majola N, Naicker N, Dlamini S, Hope TJ, Samsunder N, Abdool Karim SS, Morris L, Passmore JA, Garrett NJ. Randomized Cross-Sectional Study to Compare HIV-1 Specific Antibody and Cytokine Concentrations in Female Genital Secretions Obtained by Menstrual Cup and Cervicovaginal Lavage. PLoS One. 2015; 10(7):e0131906.
PMID:
26147923
.
Citations:
10
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Naicker N, Kharsany AB, Werner L, van Loggerenberg F, Mlisana K, Garrett N, Abdool Karim SS. Risk Factors for HIV Acquisition in High Risk Women in a Generalised Epidemic Setting. AIDS Behav. 2015 Jul; 19(7):1305-16.
PMID:
25662962
.
Citations:
16
Fields:
Acq
Acquired Immunodeficiency Synd
Beh
Behavioral Sciences
Translation:
Humans
Kashuba AD, Gengiah TN, Werner L, Yang KH, White NR, Karim QA, Abdool Karim SS. Genital Tenofovir Concentrations Correlate With Protection Against HIV Infection in the CAPRISA 004 Trial: Importance of Adherence for Microbicide Effectiveness. . 2015 Jul 01; 69(3):264-9.
PMID:
26181703
.
Citations:
30
Translation:
Humans
Arnold KB, Burgener A, Birse K, Romas L, Dunphy LJ, Shahabi K, Abou M, Westmacott GR, McCorrister S, Kwatampora J, Nyanga B, Kimani J, Masson L, Liebenberg LJ, Abdool Karim SS, Passmore JA, Lauffenburger DA, Kaul R, McKinnon LR. Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and an influx of HIV-susceptible target cells. Mucosal Immunol. 2016 Jan; 9(1):194-205.
PMID:
26104913
.
Citations:
72
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Piot P, Abdool Karim SS, Hecht R, Legido-Quigley H, Buse K, Stover J, Resch S, Ryckman T, Møgedal S, Dybul M, Goosby E, Watts C, Kilonzo N, McManus J, Sidibé M. Defeating AIDS--advancing global health. Lancet. 2015 Jul 11; 386(9989):171-218.
PMID:
26117719
.
Citations:
94
Fields:
Med
Medicine (General)
Translation:
Humans
PH
Public Health
Abdool Karim SS, Abdool Karim Q, Baxter C. Antibodies for HIV prevention in young women. Curr Opin HIV AIDS. 2015 May; 10(3):183-9.
PMID:
25700207
.
Citations:
5
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Animals
Cells
Masson L, Passmore JA, Liebenberg LJ, Werner L, Baxter C, Arnold KB, Williamson C, Little F, Mansoor LE, Naranbhai V, Lauffenburger DA, Ronacher K, Walzl G, Garrett NJ, Williams BL, Couto-Rodriguez M, Hornig M, Lipkin WI, Grobler A, Abdool Karim Q, Abdool Karim SS. Genital inflammation and the risk of HIV acquisition in women. Clin Infect Dis. 2015 Jul 15; 61(2):260-9.
PMID:
25900168
.
Citations:
119
Fields:
Com
Communicable Diseases
Translation:
Humans
Scheepers C, Shrestha RK, Lambson BE, Jackson KJ, Wright IA, Naicker D, Goosen M, Berrie L, Ismail A, Garrett N, Abdool Karim Q, Abdool Karim SS, Moore PL, Travers SA, Morris L. Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire. J Immunol. 2015 May 01; 194(9):4371-8.
PMID:
25825450
.
Citations:
24
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Sheward DJ, Ntale R, Garrett NJ, Woodman ZL, Abdool Karim SS, Williamson C. HIV-1 Superinfection Resembles Primary Infection. J Infect Dis. 2015 Sep 15; 212(6):904-8.
PMID:
25754982
.
Citations:
10
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Laeyendecker O, Redd AD, Nason M, Longosz AF, Karim QA, Naranbhai V, Garrett N, Eshleman SH, Abdool Karim SS, Quinn TC. Antibody Maturation in Women Who Acquire HIV Infection While Using Antiretroviral Preexposure Prophylaxis. J Infect Dis. 2015 Sep 01; 212(5):754-9.
PMID:
25712973
.
Citations:
15
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
PH
Public Health
Abdool Karim Q, Dellar RC, Bearnot B, Werner L, Frohlich JA, Kharsany AB, Abdool Karim SS. HIV-positive status disclosure in patients in care in rural South Africa: implications for scaling up treatment and prevention interventions. AIDS Behav. 2015 Feb; 19(2):322-9.
PMID:
25677128
.
Citations:
6
Fields:
Acq
Acquired Immunodeficiency Synd
Beh
Behavioral Sciences
Translation:
Humans
van Loggerenberg F, Grant AD, Naidoo K, Murrman M, Gengiah S, Gengiah TN, Fielding K, Abdool Karim SS. Individualised motivational counselling to enhance adherence to antiretroviral therapy is not superior to didactic counselling in South African patients: findings of the CAPRISA 058 randomised controlled trial. AIDS Behav. 2015 Jan; 19(1):145-56.
PMID:
24696226
.
Citations:
11
Fields:
Acq
Acquired Immunodeficiency Synd
Beh
Behavioral Sciences
Translation:
Humans
Mansoor LE, Abdool Karim Q, Mngadi KT, Dlamini S, Montague C, Nkomonde N, Mvandaba N, Baxter C, Gengiah TN, Samsunder N, Dawood H, Grobler A, Frohlich JA, Abdool Karim SS. Assessing the implementation effectiveness and safety of 1% tenofovir gel provision through family planning services in KwaZulu-Natal, South Africa: study protocol for an open-label randomized controlled trial. Trials. 2014 Dec 19; 15:496.
PMID:
25527071
.
Citations:
4
Fields:
Med
Medicine (General)
The
Therapeutics
Translation:
Humans
Bandawe GP, Moore PL, Werner L, Gray ES, Sheward DJ, Madiga M, Nofemela A, Thebus R, Marais JC, Maboko L, Abdool Karim SS, Hoelscher M, Morris L, Williamson C. Differences in HIV type 1 neutralization breadth in 2 geographically distinct cohorts in Africa. J Infect Dis. 2015 May 01; 211(9):1461-6.
PMID:
25398460
.
Citations:
2
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Penrose KJ, Richardson BA, Besson G, Dezzutti CS, Herold BC, Abdool Karim SS, Mellors JW, Parikh UM. Y chromosome and HIV DNA detection in vaginal swabs as biomarkers of semen and HIV exposure in women. Sex Transm Dis. 2014 Nov; 41(11):674-9.
PMID:
25299415
.
Citations:
8
Fields:
Sex
Sexually Transmitted Diseases
Translation:
Humans
Cells
CT
Clinical Trials
Abdool Karim SS. Mervyn W. Susser - his contributions to the acquired immune deficiency syndrome response in South Africa. Paediatr Perinat Epidemiol. 2014 Nov; 28(6):473-5.
PMID:
25361056
.
Citations:
Fields:
Epi
Epidemiology
Ped
Pediatrics
Per
Perinatology
Translation:
Humans
PH
Public Health
Ritchie AJ, Cai F, Smith NM, Chen S, Song H, Brackenridge S, Abdool Karim SS, Korber BT, McMichael AJ, Gao F, Goonetilleke N. Recombination-mediated escape from primary CD8+ T cells in acute HIV-1 infection. Retrovirology. 2014 Sep 12; 11:69.
PMID:
25212771
.
Citations:
14
Fields:
Vir
Virology
Translation:
Humans
Cells
Mann JK, Chopera D, Omarjee S, Kuang XT, Le AQ, Anmole G, Danroth R, Mwimanzi P, Reddy T, Carlson J, Radebe M, Goulder PJR, Walker BD, Abdool Karim S, Novitsky V, Williamson C, Brockman MA, Brumme ZL, Ndung'u T. Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure. Virology. 2014 Nov; 468-470:214-225.
PMID:
25193656
.
Citations:
10
Fields:
Vir
Virology
Translation:
Humans
Cells
Dellar RC, Abdool Karim Q, Mansoor LE, Grobler A, Humphries H, Werner L, Ntombela F, Luthuli L, Abdool Karim SS. The preventive misconception: experiences from CAPRISA 004. AIDS Behav. 2014 Sep; 18(9):1746-52.
PMID:
24715227
.
Citations:
4
Fields:
Acq
Acquired Immunodeficiency Synd
Beh
Behavioral Sciences
Translation:
Humans
Tomita A, Garrett N, Werner L, Burns JK, Ngcobo N, Zuma N, Mlisana K, van Loggerenberg F, Abdool Karim SS. Impact of antiretroviral therapy on health-related quality of life among South African women in the CAPRISA 002 acute infection study. AIDS Behav. 2014 Sep; 18(9):1801-7.
PMID:
24849623
.
Citations:
5
Fields:
Acq
Acquired Immunodeficiency Synd
Beh
Behavioral Sciences
Translation:
Humans
Gengiah TN, Botha JH, Soowamber D, Naidoo K, Abdool Karim SS. Low rifampicin concentrations in tuberculosis patients with HIV infection. J Infect Dev Ctries. 2014 Aug 13; 8(8):987-93.
PMID:
25116663
.
Citations:
15
Fields:
Com
Communicable Diseases
Translation:
Humans
Masson L, Mlisana K, Little F, Werner L, Mkhize NN, Ronacher K, Gamieldien H, Williamson C, Mckinnon LR, Walzl G, Abdool Karim Q, Abdool Karim SS, Passmore JA. Defining genital tract cytokine signatures of sexually transmitted infections and bacterial vaginosis in women at high risk of HIV infection: a cross-sectional study. Sex Transm Infect. 2014 Dec; 90(8):580-7.
PMID:
25107710
.
Citations:
56
Fields:
Sex
Sexually Transmitted Diseases
Translation:
Humans
Animals
Cells
Mlisana K, Werner L, Garrett NJ, McKinnon LR, van Loggerenberg F, Passmore JA, Gray CM, Morris L, Williamson C, Abdool Karim SS. Rapid disease progression in HIV-1 subtype C-infected South African women. Clin Infect Dis. 2014 Nov 01; 59(9):1322-31.
PMID:
25038116
.
Citations:
18
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Tomita A, Garrett N, Werner L, Burns JK, Mpanza L, Mlisana K, van Loggerenberg F, Abdool Karim SS. Health-related quality of life dynamics of HIV-positive South African women up to ART initiation: evidence from the CAPRISA 002 acute infection cohort study. AIDS Behav. 2014 Jun; 18(6):1114-23.
PMID:
24368630
.
Citations:
11
Fields:
Acq
Acquired Immunodeficiency Synd
Beh
Behavioral Sciences
Translation:
Humans
Abdool Karim Q, Kharsany AB, Leask K, Ntombela F, Humphries H, Frohlich JA, Samsunder N, Grobler A, Dellar R, Abdool Karim SS. Prevalence of HIV, HSV-2 and pregnancy among high school students in rural KwaZulu-Natal, South Africa: a bio-behavioural cross-sectional survey. Sex Transm Infect. 2014 Dec; 90(8):620-6.
PMID:
24873967
.
Citations:
23
Fields:
Sex
Sexually Transmitted Diseases
Translation:
Humans
Mansoor LE, Abdool Karim Q, Yende-Zuma N, MacQueen KM, Baxter C, Madlala BT, Grobler A, Abdool Karim SS. Adherence in the CAPRISA 004 tenofovir gel microbicide trial. AIDS Behav. 2014 May; 18(5):811-9.
PMID:
24643315
.
Citations:
10
Fields:
Acq
Acquired Immunodeficiency Synd
Beh
Behavioral Sciences
Translation:
Humans
Cells
CT
Clinical Trials
Mngadi KT, Maarschalk S, Grobler AC, Mansoor LE, Frohlich JA, Madlala B, Ngcobo N, Abdool Karim SS, Abdool Karim Q. Disclosure of microbicide gel use to sexual partners: influence on adherence in the CAPRISA 004 trial. AIDS Behav. 2014 May; 18(5):849-54.
PMID:
24633715
.
Citations:
17
Fields:
Acq
Acquired Immunodeficiency Synd
Beh
Behavioral Sciences
Translation:
Humans
Gengiah TN, Upfold M, Naidoo A, Mansoor LE, Feldblum PJ, Abdool Karim Q, Abdool Karim SS. Monitoring microbicide gel use with real-time notification of the container's opening events: results of the CAPRISA Wisebag study. AIDS Behav. 2014 May; 18(5):833-40.
PMID:
24643314
.
Citations:
4
Fields:
Acq
Acquired Immunodeficiency Synd
Beh
Behavioral Sciences
Translation:
Humans
Naidoo K, Karim QA, Bhushan A, Naidoo K, Yende-Zuma N, McHunu PK, Frohlich J, Karim F, Upfold M, Kocheleff P, Abdool Karim SS. High rates of tuberculosis in patients accessing HAART in rural South Africa. . 2014 Apr 01; 65(4):438-46.
PMID:
24256629
.
Citations:
8
Translation:
Humans
Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, DeKosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, Druz A, Garrett NJ, Hoi KH, Kong R, Louder MK, Longo NS, McKee K, Nonyane M, O'Dell S, Roark RS, Rudicell RS, Schmidt SD, Sheward DJ, Soto C, Wibmer CK, Yang Y, Zhang Z, Mullikin JC, Binley JM, Sanders RW, Wilson IA, Moore JP, Ward AB, Georgiou G, Williamson C, Abdool Karim SS, Morris L, Kwong PD, Shapiro L, Mascola JR. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature. 2014 May 01; 509(7498):55-62.
PMID:
24590074
.
Citations:
359
Fields:
Sci
Science
Translation:
Humans
Cells
Padayatchi N, Abdool Karim SS, Naidoo K, Grobler A, Friedland G. Improved survival in multidrug-resistant tuberculosis patients receiving integrated tuberculosis and antiretroviral treatment in the SAPiT Trial. Int J Tuberc Lung Dis. 2014 Feb; 18(2):147-54.
PMID:
24429305
.
Citations:
16
Fields:
Pul
Pulmonary Medicine
Translation:
Humans
Balkus JE, Richardson BA, Rabe LK, Taha TE, Mgodi N, Kasaro MP, Ramjee G, Hoffman IF, Abdool Karim SS. Bacterial vaginosis and the risk of trichomonas vaginalis acquisition among HIV-1-negative women. Sex Transm Dis. 2014 Feb; 41(2):123-8.
PMID:
24413493
.
Citations:
26
Fields:
Sex
Sexually Transmitted Diseases
Translation:
Humans
Animals
Singh R, Patel V, Mureithi MW, Naranbhai V, Ramsuran D, Tulsi S, Hiramen K, Werner L, Mlisana K, Altfeld M, Luban J, Kasprowicz V, Dheda K, Abdool Karim SS, Ndung'u T. TRIM5a and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment. J Virol. 2014 Apr; 88(8):4291-303.
PMID:
24478420
.
Citations:
7
Fields:
Vir
Virology
Translation:
Humans
Cells
Wei X, Hunt G, Abdool Karim SS, Naranbhai V, Sibeko S, Abdool Karim Q, Li JF, Kashuba AD, Werner L, Passmore JA, Morris L, Heneine W, Johnson JA. Sensitive tenofovir resistance screening of HIV-1 from the genital and blood compartments of women with breakthrough infections in the CAPRISA 004 tenofovir gel trial. J Infect Dis. 2014 Jun 15; 209(12):1916-20.
PMID:
24436453
.
Citations:
5
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Abdool Karim SS. Retrospective. Nelson R. Mandela (1918-2013). Science. 2014 Jan 10; 343(6167):150.
PMID:
24408428
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Abdool Karim SS, Baxter C. Microbicides for prevention of HIV infection: clinical efficacy trials. Curr Top Microbiol Immunol. 2014; 383:97-115.
PMID:
23695725
.
Citations:
4
Fields:
All
Allergy and Immunology
Mic
Microbiology
Translation:
Humans
Animals
Cells
Redd AD, Mullis CE, Wendel SK, Sheward D, Martens C, Bruno D, Werner L, Garrett NJ, Abdool Karim Q, Williamson C, Porcella SF, Quinn TC, Abdool Karim SS. Limited HIV-1 superinfection in seroconverters from the CAPRISA 004 Microbicide Trial. J Clin Microbiol. 2014 Mar; 52(3):844-8.
PMID:
24371237
.
Citations:
11
Fields:
Mic
Microbiology
Translation:
Humans
Cells
CT
Clinical Trials
Riou C, Burgers WA, Mlisana K, Koup RA, Roederer M, Abdool Karim SS, Williamson C, Gray CM. Differential impact of magnitude, polyfunctional capacity, and specificity of HIV-specific CD8+ T cell responses on HIV set point. J Virol. 2014 Feb; 88(3):1819-24.
PMID:
24227857
.
Citations:
19
Fields:
Vir
Virology
Translation:
Humans
Cells
Wibmer CK, Bhiman JN, Gray ES, Tumba N, Abdool Karim SS, Williamson C, Morris L, Moore PL. Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes. PLoS Pathog. 2013 Oct; 9(10):e1003738.
PMID:
24204277
.
Citations:
104
Fields:
Mic
Microbiology
Translation:
Humans
Cells
CT
Clinical Trials
Naranbhai V, Hill AV, Abdool Karim SS, Naidoo K, Abdool Karim Q, Warimwe GM, McShane H, Fletcher H. Ratio of monocytes to lymphocytes in peripheral blood identifies adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy. J Infect Dis. 2014 Feb 15; 209(4):500-9.
PMID:
24041796
.
Citations:
34
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Baxter C, Yende-Zuma N, Tshabalala P, Abdool Karim Q, Abdool Karim SS. Safety of coitally administered tenofovir 1% gel, a vaginal microbicide, in chronic hepatitis B virus carriers: results from the CAPRISA 004 trial. Antiviral Res. 2013 Sep; 99(3):405-8.
PMID:
23832086
.
Citations:
1
Fields:
Ant
Anti-Infective Agents
Vir
Virology
Translation:
Humans
Cells
Naranbhai V, Samsunder N, Sandler NG, Roque A, Abdool Karim Q, Ndung'u T, Carr WH, Altfeld M, Douek DC, Abdool Karim SS. Neither microbial translocation nor TLR responsiveness are likely explanations for preexisting immune activation in women who subsequently acquired HIV in CAPRISA 004. . 2013 Jul 01; 63(3):294-8.
PMID:
23481666
.
Citations:
3
Translation:
Humans
Cells
CT
Clinical Trials
Moore PL, Sheward D, Nonyane M, Ranchobe N, Hermanus T, Gray ES, Abdool Karim SS, Williamson C, Morris L. Multiple pathways of escape from HIV broadly cross-neutralizing V2-dependent antibodies. J Virol. 2013 May; 87(9):4882-94.
PMID:
23408621
.
Citations:
39
Fields:
Vir
Virology
Translation:
Humans
Cells
Naidoo K, Baxter C, Abdool Karim SS. When to start antiretroviral therapy during tuberculosis treatment? Curr Opin Infect Dis. 2013 Feb; 26(1):35-42.
PMID:
23188213
.
Citations:
16
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Mayosi BM, Lawn JE, van Niekerk A, Bradshaw D, Abdool Karim SS, Coovadia HM. Health in South Africa: changes and challenges since 2009. Lancet. 2012 Dec 08; 380(9858):2029-43.
PMID:
23201214
.
Citations:
143
Fields:
Med
Medicine (General)
Translation:
Humans
Grobler A, Abdool Karim S. Declining adherence is a more likely explanation than frailty of the apparent decline in efficacy in the CAPRISA 004 trial. AIDS. 2012 Nov 13; 26(17):2261; author reply 2262-3.
PMID:
23123519
.
Citations:
3
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Moore PL, Gray ES, Wibmer CK, Bhiman JN, Nonyane M, Sheward DJ, Hermanus T, Bajimaya S, Tumba NL, Abrahams MR, Lambson BE, Ranchobe N, Ping L, Ngandu N, Abdool Karim Q, Abdool Karim SS, Swanstrom RI, Seaman MS, Williamson C, Morris L. Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape. Nat Med. 2012 Nov; 18(11):1688-92.
PMID:
23086475
.