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Abdool Karim, Salim
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Salim S. Abdool Karim, Ph.D., M.Med., M.B.,Ch.B.
Title
Adjunct Professor of Immunology and Infectious Diseases
Institution
Harvard T.H. Chan School of Public Health
Department
Immunology and Infectious Diseases
Address
Harvard T.H. Chan School of Public Health
SPH 1 RM 806
665 Huntington Ave
Boston MA 02115
research activities and funding
|
selected publications
|
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
U2GPS001350
(ABDOOL KARIM, SALIM S)
Sep 30, 2008 - Sep 29, 2014
NIH
CAPRISA AIDS TREATMENT PROGRAMME
Role: Principal Investigator
UM1AI069469
(ABDOOL KARIM, QUARRAISHA)
Mar 1, 2007 - Nov 30, 2027
NIH
KwaZulu-Natal Clinical Trials Unit
Role: Principal Investigator
U01AI069469
(ABDOOL KARIM, SALIM S)
Mar 1, 2007 - Jan 31, 2014
NIH
University of KwaZulu-Natal - CAPRISA HIV/AIDS Clinical Trials Unit
Role: Principal Investigator
R21TW006111
(ABDOOL KARIM, SALIM S)
Sep 22, 2002 - Sep 21, 2003
NIH
Natal-Columbia Clinical AIDS/TB Training Program
Role: Principal Investigator
U19AI051794
(ABDOOL KARIM, SALIM S)
Jul 1, 2002 - Jun 30, 2008
NIH
COLLABORATIVE AIDS PROGRAMME OF RESEARCH IN SOUTH AFRICA
Role: Principal Investigator
U01AI048008
(RAMJEE, GITA)
Jul 1, 2000 - May 31, 2008
NIH
SOUTH AFRICA MRC HIV PREVENTION TRIALS UNIT
Role: Co-Principal Investigator
U01AI048013
(GRAY, GLENDA E)
Jul 1, 2000 - Jun 30, 2005
NIH
SOUTHERN AFRICA-NEW YORK HIV VACCINE TRIALS UNIT
Role: Co-Principal Investigator
D43TW000231
(ABDOOL KARIM, QUARRAISHA)
Jun 1, 1993 - Oct 31, 2015
NIH
Columbia University-Southern African AIDS International Training/Research Program
Role: Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Jassat W,
Abdool Karim SS
, Ozougwu L, Welch R, Mudara C, Masha M, Rousseau P, Wolmarans M, Selikow A, Govender N, Walaza S, von Gottberg A, Wolter N, Terrence Pisa P, Sanne I, Govender S, Blumberg L, Cohen C, Groome MJ. Trends in Cases, Hospitalization and Mortality Related to the Omicron BA.4/BA.5 Sub-Variants in South Africa. Clin Infect Dis. 2022 Dec 01.
PMID:
36453094
.
Citations:
Fields:
Com
Communicable Diseases
Asare K, Andine T, Naicker N, Dorward J, Singh N, Spooner E, Andriesen J, Osman F, Ngcapu S, Vandormael A, Mindel A,
Abdool Karim SS
, Bekker LG, Gray G, Corey L, Tomita A, Garrett N. Impact of point-of-care testing on the management of sexually transmitted infections in South Africa: Evidence from the HVTN702 HIV vaccine trial. Clin Infect Dis. 2022 Oct 15.
PMID:
36250382
.
Citations:
Fields:
Com
Communicable Diseases
Khan K, Karim F, Ganga Y, Bernstein M, Jule Z, Reedoy K, Cele S, Lustig G, Amoako D, Wolter N, Samsunder N, Sivro A, San JE, Giandhari J, Tegally H, Pillay S, Naidoo Y, Mazibuko M, Miya Y, Ngcobo N, Manickchund N, Magula N, Karim QA, von Gottberg A,
Abdool Karim SS
, Hanekom W, Gosnell BI, Lessells RJ, de Oliveira T, Moosa MS, Sigal A. Author Correction: Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection. Nat Commun. 2022 Oct 13; 13(1):6057.
PMID:
36229444
; PMCID:
PMC9559132
.
Citations:
Fields:
Bio
Biology
Sci
Science
Liebenberg LJP, Passmore JAS, Osman F, Jewanraj J, Mtshali A, Gerardo Garcia-Lerma J, Heneine W, Holder A, Archary D, Ngcapu S, Sivro A, Mansoor LE, Abdool Karim Q,
Abdool Karim SS
, McKinnon LR. Genital Immune Cell Activation and Tenofovir Gel Efficacy: A Case-Control Study. Clin Infect Dis. 2022 09 29; 75(6):1088-1091.
PMID:
35142337
.
Citations:
Fields:
Com
Communicable Diseases
Mazibuko-Motau N, Sobia P, Xu J, Elsherbini JA, San JE, Lewis L, Mtshali A, Mzobe G, Ntuli L,
Abdool Karim SS
, Mansoor LE, Abdool Karim Q,
Kwon DS
, Archary D, Ngcapu S. Vaginal microbial shifts are unaffected by oral pre-exposure prophylaxis in South African women. Sci Rep. 2022 09 28; 12(1):16187.
PMID:
36171447
; PMCID:
PMC9519742
.
Citations:
Fields:
Sci
Science
Translation:
Humans
PH
Public Health
Scheepers C, Kgagudi P, Mzindle N, Gray ES, Moyo-Gwete T, Lambson BE, Oosthuysen B, Mabvakure B, Garrett NJ,
Abdool Karim SS
, Morris L, Moore PL. Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies. PLoS Pathog. 2022 09; 18(9):e1010450.
PMID:
36054228
; PMCID:
PMC9477419
.
Citations:
Fields:
Mic
Microbiology
Translation:
Humans
Cells
Mahomed S, Garrett N, Capparelli EV, Osman F, Harkoo I, Yende-Zuma N, Gengiah TN, Archary D, Samsunder N, Baxter C, Mkhize NN, Modise T, Carlton K, McDermott A, Moore PL, Karim QA,
Barouch DH
, Fast PE, Mascola JR, Ledgerwood JE, Morris L,
Abdool Karim SS
. Safety and Pharmacokinetics of Monoclonal Antibodies VRC07-523LS and PGT121 Administered Subcutaneously for Human Immunodeficiency Virus Prevention. J Infect Dis. 2022 08 26; 226(3):510-520.
PMID:
35134995
; PMCID:
PMC9417124
.
Citations:
Fields:
Com
Communicable Diseases
Khan K, Lustig G, Bernstein M, Archary D, Cele S, Karim F, Smith M, Ganga Y, Jule Z, Reedoy K, Miya Y, Mthabela N, Magula NP, Lessells R, de Oliveira T, Gosnell BI,
Abdool Karim S
, Garrett N, Hanekom W, Bekker LG, Gray G, Blackburn JM, Moosa MS, Sigal A. Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Ad26.CoV2.S Vaccination in People Living With Human Immunodeficiency Virus (HIV). Clin Infect Dis. 2022 08 24; 75(1):e857-e864.
PMID:
34893824
; PMCID:
PMC8689810
.
Citations:
12
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
PH
Public Health
Abdool Karim SS
, Devnarain N. Time to Stop Using Ineffective Covid-19 Drugs. N Engl J Med. 2022 08 18; 387(7):654-655.
PMID:
36070715
.
Citations:
3
Fields:
Med
Medicine (General)
Translation:
Humans
Asare K, Osman F, Ngcapu S, Vandormael A, Naicker N, Khanyile M, Mindel A,
Abdool Karim SS
, Tomita A, Garrett N. Burden of sexually transmitted infections from acute HIV infection among women in South Africa: Evidence from a prospective cohort study. Ann Epidemiol. 2022 Oct; 74:132-139.
PMID:
35977656
.
Citations:
Fields:
Epi
Epidemiology
Translation:
Humans
Khan K, Karim F, Ganga Y, Bernstein M, Jule Z, Reedoy K, Cele S, Lustig G, Amoako D, Wolter N, Samsunder N, Sivro A, San JE, Giandhari J, Tegally H, Pillay S, Naidoo Y, Mazibuko M, Miya Y, Ngcobo N, Manickchund N, Magula N, Karim QA, von Gottberg A,
Abdool Karim SS
, Hanekom W, Gosnell BI, Lessells RJ, de Oliveira T, Moosa MS, Sigal A. Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection. Nat Commun. 2022 08 10; 13(1):4686.
PMID:
35948557
; PMCID:
PMC9364294
.
Citations:
44
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Naicker N, Yende-Zuma N, Kharsany ABM, Shozi H, Nkosi D, Naidoo A, Garrett N,
Abdool Karim SS
. Pregnancy rates and outcomes in a longitudinal HIV cohort in the context of evolving antiretroviral treatment provision in South Africa. BMC Pregnancy Childbirth. 2022 Jul 26; 22(1):596.
PMID:
35883114
; PMCID:
PMC9317085
.
Citations:
Fields:
Obs
Obstetrics
Translation:
Humans
PH
Public Health
Mansoor LE, Lewis L, Naicker CL, Harkoo I, Dawood H, Naidoo K, Gengiah TN, Samsunder N, Beesham I,
Abdool Karim SS
, Abdool Karim Q. Prospective study of oral pre-exposure prophylaxis initiation and adherence among young women in KwaZulu-Natal, South Africa. J Int AIDS Soc. 2022 07; 25(7):e25957.
PMID:
35785472
; PMCID:
PMC9251857
.
Citations:
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
PH
Public Health
Sheward DJ, Hermanus T, Murrell B, Garrett N,
Abdool Karim SS
, Morris L, Moore PL, Williamson C. HIV Coinfection Provides Insights for the Design of Vaccine Cocktails to Elicit Broadly Neutralizing Antibodies. J Virol. 2022 07 27; 96(14):e0032422.
PMID:
35758668
; PMCID:
PMC9327685
.
Citations:
Fields:
Vir
Virology
Translation:
Humans
Cells
Khan K, Karim F, Cele S, Reedoy K, San JE, Lustig G, Tegally H, Rosenberg Y, Bernstein M, Jule Z, Ganga Y, Ngcobo N, Mazibuko M, Mthabela N, Mhlane Z, Mbatha N, Miya Y, Giandhari J, Ramphal Y, Naidoo T, Sivro A, Samsunder N, Kharsany ABM, Amoako D, Bhiman JN, Manickchund N, Abdool Karim Q, Magula N,
Abdool Karim SS
, Gray G, Hanekom W, von Gottberg A, Milo R, Gosnell BI, Lessells RJ, Moore PL, de Oliveira T, Moosa MS, Sigal A. Omicron infection enhances Delta antibody immunity in vaccinated persons. Nature. 2022 07; 607(7918):356-359.
PMID:
35523247
; PMCID:
PMC9279144
.
Citations:
7
Fields:
Sci
Science
Translation:
Humans
Cells
PH
Public Health
Abdool Karim SS
, Baxter C, Abdool Karim Q. Advancing HIV prevention using tenofovir-based pre-exposure prophylaxis. Antivir Ther. 2022 04; 27(2):13596535211067589.
PMID:
35499171
.
Citations:
Fields:
Ant
Anti-Infective Agents
Vir
Virology
Translation:
Humans
PH
Public Health
Lazarus JV,
Abdool Karim SS
, van Selm L, Doran J, Batista C, Ben Amor Y, Hellard M, Kim B, Kopka CJ, Yadav P. COVID-19 vaccine wastage in the midst of vaccine inequity: causes, types and practical steps. BMJ Glob Health. 2022 04; 7(4).
PMID:
35474267
; PMCID:
PMC9044511
.
Citations:
Fields:
Epi
Epidemiology
Pub
Public Health
Translation:
Humans
PH
Public Health
Abdool Karim SS
. Public understanding of science: Communicating in the midst of a pandemic. Public Underst Sci. 2022 04; 31(3):282-287.
PMID:
35491915
.
Citations:
Fields:
His
History of Medicine
Sci
Science
Translation:
Humans
PH
Public Health
Hunter DJ
,
Abdool Karim SS
,
Baden LR
, Farrar JJ, Hamel MB,
Longo DL
,
Morrissey S
,
Rubin EJ
. Addressing Vaccine Inequity - Covid-19 Vaccines as a Global Public Good. N Engl J Med. 2022 03 24; 386(12):1176-1179.
PMID:
35196425
.
Citations:
3
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Ngcobo S, Molatlhegi RP, Osman F, Ngcapu S, Samsunder N, Garrett NJ,
Abdool Karim SS
, Abdool Karim Q, McKinnon LR, Sivro A. Pre-infection plasma cytokines and chemokines as predictors of HIV disease progression. Sci Rep. 2022 02 14; 12(1):2437.
PMID:
35165387
; PMCID:
PMC8844050
.
Citations:
2
Fields:
Sci
Science
Translation:
Humans
Cells
CT
Clinical Trials
Khan K, Karim F, Cele S, San JE, Lustig G, Tegally H, Rosenberg Y, Bernstein M, Ganga Y, Jule Z, Reedoy K, Ngcobo N, Miya Y, Mazibuko M, Mthabela N, Mhlane Z, Mbatha N, Giandhari J, Ramphal Y, Naidoo T, Manickchund N, Magula N, Karim SA, Gray G, Hanekom W, von Gottberg A, Milo R, Gosnell B, Lessells R, de Oliveira T, Moore P, Moosa YS, Sigal A. Omicron infection of vaccinated individuals enhances neutralizing immunity against the Delta variant. medRxiv. 2022 Jan 28.
PMID:
34981076
; PMCID:
PMC8722619
.
Citations:
Gengiah TN, Abdool Karim Q, Harkoo I, Mansoor L, Zuma NY, Radebe P, Samsunder N, Baxter C, Maharaj B, Baum MM, Moss JA, Pozzetto B, Hankins C,
Abdool Karim S
. CAPRISA 018: a phase I/II clinical trial study protocol to assess the safety, acceptability, tolerability and pharmacokinetics of a sustained-release tenofovir alafenamide subdermal implant for HIV prevention in women. BMJ Open. 2022 Jan 06; 12(1):e052880.
PMID:
34992111
; PMCID:
PMC8739430
.
Citations:
2
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Cele S, Jackson L, Khoury DS, Khan K, Moyo-Gwete T, Tegally H, San JE, Cromer D, Scheepers C, Amoako DG, Karim F, Bernstein M, Lustig G, Archary D, Smith M, Ganga Y, Jule Z, Reedoy K, Hwa SH, Giandhari J, Blackburn JM, Gosnell BI,
Abdool Karim SS
, Hanekom W, von Gottberg A, Bhiman JN, Lessells RJ, Moosa MS, Davenport MP, de Oliveira T, Moore PL, Sigal A. Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization. Nature. 2022 02; 602(7898):654-656.
PMID:
35016196
; PMCID:
PMC8866126
.
Citations:
197
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Cele S, Jackson L, Khoury DS, Khan K, Moyo-Gwete T, Tegally H, San JE, Cromer D, Scheepers C, Amoako D, Karim F, Bernstein M, Lustig G, Archary D, Smith M, Ganga Y, Jule Z, Reedoy K, Hwa SH, Giandhari J, Blackburn JM, Gosnell BI,
Abdool Karim SS
, Hanekom W, von Gottberg A, Bhiman J, Lessells RJ, Moosa MS, Davenport MP, de Oliveira T, Moore PL, Sigal A. SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection. medRxiv. 2021 Dec 17.
PMID:
34909788
; PMCID:
PMC8669855
.
Citations:
1
Sobia P, Pillay T, Liebenberg LJP, Sivro A, Mansoor LE, Osman F, Passmore JS, Abdool Karim Q,
Abdool Karim SS
, Baxter C, McKinnon LR, Archary D. Higher mucosal antibody concentrations in women with genital tract inflammation. Sci Rep. 2021 12 06; 11(1):23514.
PMID:
34873252
; PMCID:
PMC8648917
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Rubin EJ
,
Baden LR
,
Abdool Karim SS
, Morrissey S. Audio Interview: The Omicron Variant of SARS-CoV-2. N Engl J Med. 2021 Dec 02; 385(23):e96.
PMID:
34874638
.
Citations:
2
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
PH
Public Health
Abdool Karim SS
, Kelemu S, Baxter C. COVID-19 in Africa: Catalyzing change for sustainable development. PLoS Med. 2021 11; 18(11):e1003869.
PMID:
34843497
; PMCID:
PMC8668091
.
Citations:
Fields:
Med
Medicine (General)
Translation:
Humans
Mielke D, Bandawe G, Zheng J, Jones J, Abrahams MR, Bekker V, Ochsenbauer C, Garrett N,
Abdool Karim S
, Moore PL, Morris L, Montefiori D, Anthony C, Ferrari G, Williamson C. ADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection. PLoS Pathog. 2021 11; 17(11):e1010046.
PMID:
34788337
.
Citations:
3
Fields:
Mic
Microbiology
Translation:
Humans
Cells
Ismail SD, Riou C, Joseph SB, Archin NM, Margolis DM, Perelson AS, Cassidy T, Abrahams MR, Moeser M, Council OD, McKinnon LR, Osman F, Karim QA,
Abdool Karim SS
, Swanstrom R, Williamson C, Garrett NJ, Burgers WA. Immunological Correlates of the HIV-1 Replication-Competent Reservoir Size. Clin Infect Dis. 2021 10 20; 73(8):1528-1531.
PMID:
34181706
; PMCID:
PMC8528395
.
Citations:
2
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Mtshali A, San JE, Osman F, Garrett N, Balle C, Giandhari J, Onywera H, Mngomezulu K, Mzobe G, de Oliveira T, Rompalo A, Mindel A,
Abdool Karim SS
, Ravel J, Passmore JS, Abdool Karim Q, Jaspan HB, Liebenberg LJP, Ngcapu S. Temporal Changes in Vaginal Microbiota and Genital Tract Cytokines Among South African Women Treated for Bacterial Vaginosis. Front Immunol. 2021; 12:730986.
PMID:
34594336
.
Citations:
2
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Jewanraj J, Ngcapu S, Osman F, Ramsuran V, Fish M, Mtshali A, Singh R, Mansoor LE,
Abdool Karim SS
, Abdool Karim Q, Passmore JS, Liebenberg LJP. Transient association between semen exposure and biomarkers of genital inflammation in South African women at risk of HIV infection. J Int AIDS Soc. 2021 06; 24(6):e25766.
PMID:
34164927
; PMCID:
PMC8223121
.
Citations:
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
CT
Clinical Trials
Singh R, Ramsuran V,
Naranbhai V
, Yende-Zuma N, Garrett N, Mlisana K, Dong KL,
Walker BD
,
Abdool Karim SS
, Carrington M, Ndung'u T. Epigenetic Regulation of BST-2 Expression Levels and the Effect on HIV-1 Pathogenesis. Front Immunol. 2021; 12:669241.
PMID:
34025670
; PMCID:
PMC8131512
.
Citations:
2
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Pillay K, Lewis L, Rambaran S, Yende-Zuma N, Archary D, Gengiah S, Govender D, Hassan-Moosa R, Samsunder N,
Abdool Karim SS
, McKinnon LR, Padayatchi N, Naidoo K, Sivro A. Plasma Biomarkers of Risk of Tuberculosis Recurrence in HIV Co-Infected Patients From South Africa. Front Immunol. 2021; 12:631094.
PMID:
33841412
.
Citations:
Fields:
All
Allergy and Immunology
Translation:
Humans
Abdool Karim SS
, de Oliveira T. New SARS-CoV-2 Variants - Clinical, Public Health, and Vaccine Implications. N Engl J Med. 2021 05 13; 384(19):1866-1868.
PMID:
33761203
; PMCID:
PMC8008749
.
Citations:
253
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Abdool Karim SS
, de Oliveira T, Loots G. Appropriate names for COVID-19 variants. Science. 2021 03 19; 371(6535):1215.
PMID:
33737481
.
Citations:
7
Fields:
Sci
Science
Translation:
Humans
Cells
Garrett N, Mtshali A, Osman F, Masson L, McKinnon LR, Singh R, Mitchev N, Ngobese H, Kharsany ABM,
Abdool Karim S
, Mlisana K, Passmore JA, Rompalo A, Mindel A, Liebenberg L. Impact of point-of-care testing and treatment of sexually transmitted infections and bacterial vaginosis on genital tract inflammatory cytokines in a cohort of young South African women. Sex Transm Infect. 2021 12; 97(8):555-565.
PMID:
33608480
.
Citations:
1
Fields:
Sex
Sexually Transmitted Diseases
Translation:
Humans
Mahomed S, Garrett N, Baxter C, Abdool Karim Q,
Abdool Karim SS
. Clinical Trials of Broadly Neutralizing Monoclonal Antibodies for Human Immunodeficiency Virus Prevention: A Review. J Infect Dis. 2021 02 13; 223(3):370-380.
PMID:
32604408
; PMCID:
PMC8508778
.
Citations:
10
Fields:
Com
Communicable Diseases
Translation:
Humans
Cells
Rubin EJ
,
Baden LR
,
Abdool Karim SS
, Morrissey S. Audio Interview: Covid-19 in South Africa and a New SARS-CoV-2 Variant. N Engl J Med. 2021 Jan 14; 384(2):e14.
PMID:
33497556
.
Citations:
2
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
PH
Public Health
Mahomed S, Garrett N, Karim QA, Zuma NY, Capparelli E, Baxter C, Gengiah T, Archary D, Samsunder N, Rose ND, Moore P, Williamson C,
Barouch DH
, Fast PE, Pozzetto B, Hankins C, Carlton K, Ledgerwood J, Morris L, Mascola J,
Abdool Karim S
. Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial. BMJ Open. 2020 11 26; 10(11):e042247.
PMID:
33243815
.
Citations:
8
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
CT
Clinical Trials
Scheepers C, Bekker V, Anthony C, Richardson SI, Oosthuysen B, Moyo T, Kgagudi P, Kitchin D, Nonyane M, York T, Mielke D, Mabvakure BM, Sheng Z, Lambson BE, Ismail A, Garrett NJ,
Abdool Karim SS
, Shapiro L, Williamson C, Morris L, Moore PL. Antibody Isotype Switching as a Mechanism to Counter HIV Neutralization Escape. Cell Rep. 2020 11 24; 33(8):108430.
PMID:
33238131
.
Citations:
4
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Jewanraj J, Ngcapu S, Osman F, Mtshali A, Singh R, Mansoor LE,
Abdool Karim SS
, Abdool Karim Q, Passmore JS, Liebenberg LJP. The Impact of Semen Exposure on the Immune and Microbial Environments of the Female Genital Tract. Front Reprod Health. 2020; 2:566559.
PMID:
36304709
; PMCID:
PMC9580648
.
Citations:
1
Baxter C, Abdool Karim Q,
Abdool Karim SS
. Identifying SARS-CoV-2 infections in South Africa: Balancing public health imperatives with saving lives. Biochem Biophys Res Commun. 2021 01 29; 538:221-225.
PMID:
33143875
.
Citations:
3
Fields:
Bio
Biochemistry
Bio
Biophysics
Translation:
Humans
Cells
PH
Public Health
Cromarty R, Sigal A, Liebenberg LJ, Mckinnon LR,
Abdool Karim SS
, Passmore JS, Archary D. Betamethasone induces potent immunosuppression and reduces HIV infection in a PBMC in vitro model. J Investig Med. 2021 01; 69(1):28-40.
PMID:
33004468
; PMCID:
PMC7803916
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
PH
Public Health
Brault MA,
Spiegelman D
,
Abdool Karim SS
, Vermund SH. Correction to: Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials. Curr HIV/AIDS Rep. 2020 Oct; 17(5):577.
PMID:
32601917
.
Citations:
1
Fields:
Acq
Acquired Immunodeficiency Synd
Abdool Karim Q,
Abdool Karim SS
. COVID-19 affects HIV and tuberculosis care. Science. 2020 07 24; 369(6502):366-368.
PMID:
32703860
.
Citations:
19
Fields:
Sci
Science
Translation:
Humans
PH
Public Health
Fisher KL, Mabuka JM, Sivro A, Ngcapu S, Passmore JS, Osman F, Ndlovu B, Abdool Karim Q,
Abdool Karim SS
, Chung AW, Baxter C, Archary D. Topical Tenofovir Pre-exposure Prophylaxis and Mucosal HIV-Specific Fc-Mediated Antibody Activities in Women. Front Immunol. 2020; 11:1274.
PMID:
32733445
.
Citations:
1
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
PH
Public Health
Brault MA,
Spiegelman D
,
Abdool Karim SS
, Vermund SH. Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials. Curr HIV/AIDS Rep. 2020 06; 17(3):249-258.
PMID:
32297219
.
Citations:
3
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
PH
Public Health
Abdool Karim SS
. The South African Response to the Pandemic. N Engl J Med. 2020 06 11; 382(24):e95.
PMID:
32469479
; PMCID:
PMC7281717
.
Citations:
36
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
PH
Public Health
Abdool Karim S
. Criminalisation of transmission of SARS-CoV-2: A potential challenge to controlling the outbreak in South Africa. S Afr Med J. 2020 04 22; 110(6):458-460.
PMID:
32880551
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
PH
Public Health
Drain PK, Dorward J, Violette LR, Quame-Amaglo J, Thomas KK, Samsunder N, Ngobese H, Mlisana K, Moodley P, Donnell D,
Barnabas RV
, Naidoo K,
Abdool Karim SS
, Celum C, Garrett N. Point-of-care HIV viral load testing combined with task shifting to improve treatment outcomes (STREAM): findings from an open-label, non-inferiority, randomised controlled trial. Lancet HIV. 2020 04; 7(4):e229-e237.
PMID:
32105625
; PMCID:
PMC7183312
.
Citations:
25
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Cells
Molatlhegi RP, Liebenberg LJ, Leslie A, Noel-Romas L, Mabhula A, Mchunu N, Perner M, Birse K, Ngcapu S, Adamson JH, Govender K, Garrett NJ, Samsunder N, Burgener AD,
Abdool Karim SS
, Abdool Karim Q, Passmore JS, McKinnon LR. Plasma concentration of injectable contraceptive correlates with reduced cervicovaginal growth factor expression in South African women. Mucosal Immunol. 2020 05; 13(3):449-459.
PMID:
31896762
.
Citations:
7
Fields:
All
Allergy and Immunology
Translation:
Humans
Richardson SI, Lambson BE, Crowley AR, Bashirova A, Scheepers C, Garrett N,
Abdool Karim S
, Mkhize NN, Carrington M, Ackerman ME, Moore PL, Morris L. IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody. PLoS Pathog. 2019 12; 15(12):e1008064.
PMID:
31841557
.
Citations:
24
Fields:
Mic
Microbiology
Translation:
Humans
Mielke D, Bandawe G, Pollara J, Abrahams MR, Nyanhete T, Moore PL, Thebus R, Yates NL, Kappes JC, Ochsenbauer C, Garrett N,
Abdool Karim S
, Tomaras GD, Montefiori D, Morris L, Ferrari G, Williamson C. Antibody-Dependent Cellular Cytotoxicity (ADCC)-Mediating Antibodies Constrain Neutralizing Antibody Escape Pathway. Front Immunol. 2019; 10:2875.
PMID:
31921139
.
Citations:
12
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Liebenberg LJP, McKinnon LR, Yende-Zuma N, Garrett N, Baxter C, Kharsany ABM, Archary D, Rositch A, Samsunder N, Mansoor LE, Passmore JS,
Abdool Karim SS
, Abdool Karim Q. HPV infection and the genital cytokine milieu in women at high risk of HIV acquisition. Nat Commun. 2019 11 19; 10(1):5227.
PMID:
31745084
.
Citations:
9
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Kharsany ABM, Cawood C, Lewis L, Yende-Zuma N, Khanyile D, Puren A, Madurai S, Baxter C, George G, Govender K, Beckett S, Samsunder N, Toledo C, Ayalew KA, Diallo K, Glenshaw M, Herman-Roloff A, Wilkinson E, de Oliveira T,
Abdool Karim SS
, Abdool Karim Q. Trends in HIV Prevention, Treatment, and Incidence in a Hyperendemic Area of KwaZulu-Natal, South Africa. JAMA Netw Open. 2019 11 01; 2(11):e1914378.
PMID:
31675082
.
Citations:
15
Fields:
Med
Medicine (General)
Translation:
Humans
PH
Public Health
Mwatelah R, McKinnon LR, Baxter C, Abdool Karim Q,
Abdool Karim SS
. Mechanisms of sexually transmitted infection-induced inflammation in women: implications for HIV risk. J Int AIDS Soc. 2019 08; 22 Suppl 6:e25346.
PMID:
31468677
; PMCID:
PMC6715949
.
Citations:
19
Fields:
Acq
Acquired Immunodeficiency Synd
Translation:
Humans
Cromarty R, Sigal A, Liebenberg LJP, McKinnon LR,
Abdool Karim SS
, Passmore JS, Archary D. Diminished HIV Infection of Target CD4+ T Cells in a Toll-Like Receptor 4 Stimulated in vitro Model. Front Immunol. 2019; 10:1705.
PMID:
31396221
.
Citations:
6
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Abdool Karim SS
. HIV-1 Epidemic Control - Insights from Test-and-Treat Trials. N Engl J Med. 2019 07 18; 381(3):286-288.
PMID:
31314975
.
Citations:
30
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
PH
Public Health
Mahomed S, Garrett N, Capparelli E, Baxter C, Zuma NY, Gengiah T, Archary D, Moore P, Samsunder N,
Barouch DH
, Mascola J, Ledgerwood J, Morris L,
Abdool Karim S
. Assessing the safety and pharmacokinetics of the monoclonal antibodies, VRC07-523LS and PGT121 in HIV negative women in South Africa: study protocol for the CAPRISA 012A randomised controlled phase I trial. BMJ Open. 2019 07 03; 9(7):e030283.
PMID:
31272988
.
Citations:
7
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials