Harvard Catalyst Profiles

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Benjamin Spurgeon, Ph.D.

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2021 - 2024
ISAC Marylou Ingram Scholar

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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Spurgeon BEJ, Frelinger III AL. Platelet phenotyping by full spectrum flow cytometry. Current Protocols. 2023; 3(2):e687.
  2. Spurgeon BEJ, Frelinger III AL. Comprehensive phenotyping of human platelets by single-cell cytometry. Cytometry Part A. 2022; 101(4):290-297.
  3. Hindle MS, Spurgeon BEJ, Cheah LT, Webb BA, Naseem KM. Multidimensional flow cytometry reveals novel platelet subpopulations in response to prostacyclin. Journal of Thrombosis and Haemostasis. 2021; 19(7):1800-1812.
  4. Spurgeon BE, Linden MD, Michelson AD, Frelinger AL. Immunophenotypic analysis of platelets by flow cytometry. Current Protocols. 2021; 1(6):e178.
  5. Spurgeon BEJ, Michelson AD, Frelinger AL. Platelet immunophenotyping by high-dimensional mass cytometry. Current Protocols. 2021; 1(5):e112.
  6. Spurgeon BEJ, Michelson AD, Frelinger III AL. Platelet mass cytometry: Optimization of sample, reagent, and analysis parameters. Cytometry Part A. 2021; 99(2):170-179.
  7. Aburima A, Berger M, Spurgeon BEJ, Webb BA, Wraith KS, Febbraio M, Poole AW, Naseem KM. Thrombospondin-1 promotes hemostasis through modulation of cAMP signaling in blood platelets. Blood. 2021; 137(5):678-689.
  8. Spurgeon BEJ, Naseem KM. Phosphoflow cytometry and barcoding in blood platelets: Technical and analytical considerations. Cytometry Part B: Clinical Cytometry. 2020; 98(2):123-130.
  9. Berger M, Raslan Z, Aburima A, Magwenzi S, Wraith KS, Spurgeon BEJ, Hindle MS, Law R, Febbraio M, Naseem KM. Atherogenic lipid stress induces platelet hyperactivity through CD36-mediated hyposensitivity to prostacyclin: the role of phosphodiesterase 3A. Haematologica. 2020; 105(3):808-819.
  10. Spurgeon BEJ, Naseem KM. Platelet flow cytometry: Instrument setup, controls, and panel performance. Cytometry Part B: Clinical Cytometry. 2020; 98(1):19-27.
  11. Kearney KJ, Pechlivani N, King R, Tiede C, Phoenix F, Cheah R, Macrae F, Simmons KJ, Manfield IW, Smith KA, Spurgeon BEJ, Naseem KM, Ariens RAS, McPherson MJ, Tomlinson DC, Ajjan RA. Affimer proteins as a tool to modulate fibrinolysis, stabilize the bloot clot, and reduce bleeding complications. Blood. 2019; 133(11):1233-1244.
  12. Spurgeon BEJ, Naseem KM. High-throughput signaling profiling in blood platelets by multiplexed phosphoflow cytometry. Platelets and Megakaryocytes. Methods in Molecular Biology. Gibbins J, Mahaut-Smith M (Eds). 2018; 1812:95-111.
  13. Konya J, Spurgeon BEJ, Al Qaissi A, Sathyapalan T, Ajjan R, Madden L, Garrett AT, Kilpatrick ES, Atkin SL. The effect of a simulated commercial flight environment with hypoxia and low humidity on clotting, platelet, and endothelial function in participants with type 2 diabetes – a cross-over study. Frontiers in Endocrinology. 2018; 9(26).
  14. Kahal H, Aburima A, Spurgeon B, Wraith KS, Rigby AS, Sathyapalan T, Kilpatrick ES, Naseem KM, Atkin SL. Platelet function following induced hypoglycaemia in type 2 diabetes. Diabetes & Metabolism. 2018; 44(5):431-436.
  15. Spurgeon BE, Aburima A, Oberprieler NG, Taskén K, Naseem KM. Phosphospecific flow cytometry enables large-scale signaling profiling and drug screening in blood platelets. Journal of Thrombosis and Haemostasis. 2014; 12(10):1733-1743.
  16. Aye MM, Kilpatrick ES, Aburima A, Wraith KS, Magwenzi S, Spurgeon B, Rigby AS, Sandeman D, Naseem KM, Atkin SL. Acute hypertriglyceridemia induces platelet hyperactivity that is not attenuated by insulin in polycystic ovary syndrome. Journal of the American Heart Association. 2014; 3(1).
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© 2023 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.