Harvard Catalyst Profiles

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John Vincent Frangioni, M.D., Ph.D.

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Department
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Other Positions
Title
Institution
Department

Mentoring
Novel Anti-polymerization "Agents for the Treatment of Sickle Cell Anemia"
Summer, 07/01/01 - 08/30/01
Development of a Cell-Permeable Anti-Polymerization Peptide for Sickle Cell Disease
Part Time/Continuation, 09/01/01 - 03/10/02

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA207500 (FRANGIONI, JOHN V) Dec 9, 2016 - Nov 30, 2021
    NIH/NCI
    Mediastinal Lymph Node Identification in Lung Cancer using NIR Fluorescent VATS
    Role: Principal Investigator
  2. R44CA210820 (FRANGIONI, JOHN V) Dec 8, 2016 - Nov 30, 2018
    NIH/NCI
    ZW800-1: The 1st Zwitterionic NIR Fluorophore for Cancer Imaging & Ureter Mapping
    Role: Principal Investigator
  3. R01CA185457 (FRANGIONI, JOHN V) Sep 25, 2014 - Aug 31, 2019
    NIH/NCI
    (PQC-5) Zwitterionic NIR/Zr-89 Agents for Prostate Cancer Staging and Treatment
    Role: Principal Investigator
  4. R01DE022820 (FRANGIONI, JOHN V) Feb 1, 2013 - Jan 31, 2018
    NIH/NIDCR
    Real-Time Flap Viability Monitoring during Facial Transplantation using SFDI
    Role: Principal Investigator
  5. R01EB010022 (FRANGIONI, JOHN V) Aug 1, 2010 - Jul 31, 2015
    NIH/NIBIB
    Ultra-Low Background NIR Fluorophores for In Vivo Imaging and Image-Guided Surger
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Holzapfel M, Mutas M, Chandralingam S, von Salisch C, Peric N, Segelke T, Fischer M, Chakraborty I, Parak WJ, Frangioni JV, Maison W. Nonradioactive Cell Assay for the Evaluation of Modular Prostate-Specific Membrane Antigen Targeting Ligands via Inductively Coupled Plasma Mass Spectrometry. J Med Chem. 2019 Dec 12; 62(23):10912-10918. PMID: 31714783.
    Citations:    
  2. de Valk KS, Handgraaf HJ, Deken MM, Sibinga Mulder BG, Valentijn AR, Terwisscha van Scheltinga AG, Kuil J, van Esdonk MJ, Vuijk J, Bevers RF, Peeters KC, Holman FA, Frangioni JV, Burggraaf J, Vahrmeijer AL. A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery. Nat Commun. 2019 07 16; 10(1):3118. PMID: 31311922.
    Citations:    
  3. Sibinga Mulder BG, Handgraaf HJ, Vugts DJ, Sewing C, Windhorst AD, Stammes M, de Geus-Oei LF, Bordo MW, Mieog JSD, van de Velde CJ, Frangioni JV, Vahrmeijer AL. A dual-labeled cRGD-based PET/optical tracer for pre-operative staging and intraoperative treatment of colorectal cancer. Am J Nucl Med Mol Imaging. 2018; 8(5):282-291. PMID: 30510846.
    Citations:    
  4. Handgraaf HJM, Boogerd LSF, Höppener DJ, Peloso A, Sibinga Mulder BG, Hoogstins CES, Hartgrink HH, van de Velde CJH, Mieog JSD, Swijnenburg RJ, Putter H, Maestri M, Braat AE, Frangioni JV, Vahrmeijer AL. Long-term follow-up after near-infrared fluorescence-guided resection of colorectal liver metastases: A retrospective multicenter analysis. Eur J Surg Oncol. 2017 Aug; 43(8):1463-1471. PMID: 28528189.
    Citations: 5     Fields:    Translation:Humans
  5. Tummers WS, Warram JM, Tipirneni KE, Fengler J, Jacobs P, Shankar L, Henderson L, Ballard B, Pfefer TJ, Pogue BW, Weichert JP, Bouvet M, Sorger J, Contag CH, Frangioni JV, Tweedle MF, Basilion JP, Gambhir SS, Rosenthal EL. Regulatory Aspects of Optical Methods and Exogenous Targets for Cancer Detection. Cancer Res. 2017 05 01; 77(9):2197-2206. PMID: 28428283.
    Citations: 4     Fields:    Translation:Humans
  6. Handgraaf HJM, Boonstra MC, Prevoo HAJM, Kuil J, Bordo MW, Boogerd LSF, Sibinga Mulder BG, Sier CFM, Vinkenburg-van Slooten ML, Valentijn ARPM, Burggraaf J, van de Velde CJH, Frangioni JV, Vahrmeijer AL. Real-time near-infrared fluorescence imaging using cRGD-ZW800-1 for intraoperative visualization of multiple cancer types. Oncotarget. 2017 Mar 28; 8(13):21054-21066. PMID: 28416744.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  7. Wada H, Vargas CR, Angelo J, Faulkner-Jones B, Paul MA, Ho OA, Lee BT, Frangioni JV. Accurate Prediction of Tissue Viability at Postoperative Day 7 Using Only Two Intraoperative Subsecond Near-Infrared Fluorescence Images. Plast Reconstr Surg. 2017 Feb; 139(2):354-363. PMID: 28121867.
    Citations: 1     Fields:    Translation:Animals
  8. Wada H, Hyun H, Kang H, Gravier J, Henary M, Bordo MW, Choi HS, Frangioni JV. Intraoperative Near-Infrared Fluorescence Imaging of Thymus in Preclinical Models. Ann Thorac Surg. 2017 Apr; 103(4):1132-1141. PMID: 27964920.
    Citations:    Fields:    Translation:Animals
  9. Ashitate Y, Levitz A, Park MH, Hyun H, Venugopal V, Park G, El Fakhri G, Henary M, Gioux S, Frangioni JV, Choi HS. Endocrine-specific NIR fluorophores for adrenal gland targeting. Chem Commun (Camb). 2016 Aug 11; 52(67):10305-8. PMID: 27476533.
    Citations: 4     Fields:    Translation:Humans
  10. Boogerd LS, Handgraaf HJ, Lam HD, Huurman VA, Farina-Sarasqueta A, Frangioni JV, van de Velde CJ, Braat AE, Vahrmeijer AL. Laparoscopic detection and resection of occult liver tumors of multiple cancer types using real-time near-infrared fluorescence guidance. Surg Endosc. 2017 02; 31(2):952-961. PMID: 27357928.
    Citations: 11     Fields:    Translation:Humans
  11. Tummers QR, Boogerd LS, de Steur WO, Verbeek FP, Boonstra MC, Handgraaf HJ, Frangioni JV, van de Velde CJ, Hartgrink HH, Vahrmeijer AL. Near-infrared fluorescence sentinel lymph node detection in gastric cancer: A pilot study. World J Gastroenterol. 2016 Apr 07; 22(13):3644-51. PMID: 27053856.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  12. Vargas CR, Nguyen JT, Ashitate Y, Angelo J, Venugopal V, Kettenring F, Neacsu F, Frangioni JV, Gioux S, Lee BT. Intraoperative Hemifacial Composite Flap Perfusion Assessment Using Spatial Frequency Domain Imaging: A Pilot Study in Preparation for Facial Transplantation. Ann Plast Surg. 2016 Feb; 76(2):249-55. PMID: 26418791.
    Citations:    Fields:    Translation:Animals
  13. Hyun H, Henary M, Gao T, Narayana L, Owens EA, Lee JH, Park G, Wada H, Ashitate Y, Frangioni JV, Choi HS. 700-nm Zwitterionic Near-Infrared Fluorophores for Dual-Channel Image-Guided Surgery. Mol Imaging Biol. 2016 Feb; 18(1):52-61. PMID: 26084246.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  14. Boogerd LS, Handgraaf HJ, Lam HD, Braat AE, Baranski AG, Swijnenburg RJ, Frangioni JV, Vahrmeijer AL, Ringers J. Application of near-infrared fluorescence imaging during modified associating liver partition and portal vein ligation for staged hepatectomy. Surgery. 2016 May; 159(5):1481-2. PMID: 26817963.
    Citations: 2     Fields:    Translation:Humans
  15. Verbeek FP, Tummers QR, Rietbergen DD, Peters AA, Schaafsma BE, van de Velde CJ, Frangioni JV, van Leeuwen FW, Gaarenstroom KN, Vahrmeijer AL. Sentinel Lymph Node Biopsy in Vulvar Cancer Using Combined Radioactive and Fluorescence Guidance. Int J Gynecol Cancer. 2015 Jul; 25(6):1086-93. PMID: 25768079.
    Citations: 8     Fields:    Translation:Humans
  16. Tummers QR, Hoogstins CE, Peters AA, de Kroon CD, Trimbos JB, van de Velde CJ, Frangioni JV, Vahrmeijer AL, Gaarenstroom KN. The Value of Intraoperative Near-Infrared Fluorescence Imaging Based on Enhanced Permeability and Retention of Indocyanine Green: Feasibility and False-Positives in Ovarian Cancer. PLoS One. 2015; 10(6):e0129766. PMID: 26110901.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  17. Boonstra MC, Tolner B, Schaafsma BE, Boogerd LS, Prevoo HA, Bhavsar G, Kuppen PJ, Sier CF, Bonsing BA, Frangioni JV, van de Velde CJ, Chester KA, Vahrmeijer AL. Preclinical evaluation of a novel CEA-targeting near-infrared fluorescent tracer delineating colorectal and pancreatic tumors. Int J Cancer. 2015 Oct 15; 137(8):1910-20. PMID: 25895046.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  18. Boonstra MC, van Driel PB, van Willigen DM, Stammes MA, Prevoo HA, Tummers QR, Mazar AP, Beekman FJ, Kuppen PJ, van de Velde CJ, Löwik CW, Frangioni JV, van Leeuwen FW, Sier CF, Vahrmeijer AL. uPAR-targeted multimodal tracer for pre- and intraoperative imaging in cancer surgery. Oncotarget. 2015 Jun 10; 6(16):14260-73. PMID: 25895028.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  19. Hyun H, Owens EA, Wada H, Levitz A, Park G, Park MH, Frangioni JV, Henary M, Choi HS. Cartilage-Specific Near-Infrared Fluorophores for Biomedical Imaging. Angew Chem Int Ed Engl. 2015 Jul 20; 54(30):8648-52. PMID: 26095685.
    Citations: 14     Fields:    Translation:Animals
  20. Wada H, Hyun H, Vargas C, Genega EM, Gravier J, Gioux S, Frangioni JV, Choi HS. Sentinel Lymph Node Mapping of Liver. Ann Surg Oncol. 2015 Dec; 22 Suppl 3:S1147-55. PMID: 25968620.
    Citations: 4     Fields:    Translation:Animals
  21. Handgraaf HJ, Boogerd LS, Verbeek FP, Tummers QR, Hardwick JC, Baeten CI, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Intraoperative fluorescence imaging to localize tumors and sentinel lymph nodes in rectal cancer. Minim Invasive Ther Allied Technol. 2016; 25(1):48-53. PMID: 25950124.
    Citations: 4     Fields:    Translation:Humans
  22. Tummers QR, Schepers A, Hamming JF, Kievit J, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Intraoperative guidance in parathyroid surgery using near-infrared fluorescence imaging and low-dose Methylene Blue. Surgery. 2015 Nov; 158(5):1323-30. PMID: 25958068.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  23. Gibbs SL, Genega E, Salemi J, Kianzad V, Goodwill HL, Xie Y, Oketokoun R, Khurd P, Kamen A, Frangioni JV. Near-Infrared Fluorescent Digital Pathology for the Automation of Disease Diagnosis and Biomarker Assessment. Mol Imaging. 2015 May 01; 14(5):7290201500005. PMID: 28654346.
    Citations:    
  24. Bordo MW, Oketokoun R, Cross CJ, Bao K, Lee JH, Feygin I, Chang AB, Frangioni JV, Choi HS. High-Throughput Sorting and Placement of One-Bead-One-Compound (OBOC) Libraries from Bulk to Single Wells in Organic Solvent. ACS Comb Sci. 2015 May 11; 17(5):303-9. PMID: 25879633.
    Citations:    Fields:    
  25. Vargas CR, Nguyen JT, Ashitate Y, Silvestre J, Venugopal V, Neacsu F, Kettenring F, Frangioni JV, Gioux S, Lee BT. Near-infrared imaging for the assessment of anastomotic patency, thrombosis, and reperfusion in microsurgery: a pilot study in a porcine model. Microsurgery. 2015 May; 35(4):309-14. PMID: 25571855.
    Citations: 2     Fields:    Translation:Animals
  26. Hyun H, Park MH, Owens EA, Wada H, Henary M, Handgraaf HJ, Vahrmeijer AL, Frangioni JV, Choi HS. Structure-inherent targeting of near-infrared fluorophores for parathyroid and thyroid gland imaging. Nat Med. 2015 Feb; 21(2):192-7. PMID: 25559343.
    Citations: 32     Fields:    Translation:Animals
  27. Wada H, Hyun H, Vargas C, Gravier J, Park G, Gioux S, Frangioni JV, Henary M, Choi HS. Pancreas-targeted NIR fluorophores for dual-channel image-guided abdominal surgery. Theranostics. 2015; 5(1):1-11. PMID: 25553094.
    Citations: 14     Fields:    Translation:Animals
  28. Gibbs SL, Genega E, Salemi J, Kianzad V, Goodwill HL, Xie Y, Oketokoun R, Khurd P, Kamen A, Frangioni JV. Near-infrared fluorescent digital pathology for the automation of disease diagnosis and biomarker assessment. Mol Imaging. 2015; 14. PMID: 25812603.
    Citations: 1     Fields:    Translation:Humans
  29. Lee JH, Bao K, Frangioni JV, Choi HS. Screening of Small Molecule Microarrays for Ligands Targeted to the Extracellular Epitopes of Living Cells. Microarrays (Basel). 2015; 4(1):53-63. PMID: 26435848.
    Citations: 1     
  30. Tummers QR, Boonstra MC, Frangioni JV, van de Velde CJ, Vahrmeijer AL, Bonsing BA. Intraoperative near-infrared fluorescence imaging of a paraganglioma using methylene blue: A case report. Int J Surg Case Rep. 2015; 6C:150-3. PMID: 25541370.
    Citations: 5     
  31. Inoue K, Gibbs SL, Liu F, Lee JH, Xie Y, Ashitate Y, Fujii H, Frangioni JV, Choi HS. Microscopic validation of macroscopic in vivo images enabled by same-slide optical and nuclear fusion. J Nucl Med. 2014 Nov; 55(11):1899-904. PMID: 25324521.
    Citations:    Fields:    Translation:HumansAnimals
  32. Hyun H, Wada H, Bao K, Gravier J, Yadav Y, Laramie M, Henary M, Frangioni JV, Choi HS. Phosphonated near-infrared fluorophores for biomedical imaging of bone. Angew Chem Int Ed Engl. 2014 Sep 26; 53(40):10668-72. PMID: 25139079.
    Citations: 15     Fields:    Translation:Animals
  33. Schaafsma BE, Verbeek FP, Elzevier HW, Tummers QR, van der Vorst JR, Frangioni JV, van de Velde CJ, Pelger RC, Vahrmeijer AL. Optimization of sentinel lymph node mapping in bladder cancer using near-infrared fluorescence imaging. J Surg Oncol. 2014 Dec; 110(7):845-50. PMID: 25111761.
    Citations: 9     Fields:    Translation:Humans
  34. Park MH, Hyun H, Ashitate Y, Wada H, Park G, Lee JH, Njiojob C, Henary M, Frangioni JV, Choi HS. Prototype nerve-specific near-infrared fluorophores. Theranostics. 2014; 4(8):823-33. PMID: 24955143.
    Citations: 19     Fields:    Translation:Animals
  35. Tummers QR, Verbeek FP, Prevoo HA, Braat AE, Baeten CI, Frangioni JV, van de Velde CJ, Vahrmeijer AL. First experience on laparoscopic near-infrared fluorescence imaging of hepatic uveal melanoma metastases using indocyanine green. Surg Innov. 2015 Feb; 22(1):20-5. PMID: 24902685.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  36. Ashitate Y, Hyun H, Kim SH, Lee JH, Henary M, Frangioni JV, Choi HS. Simultaneous mapping of pan and sentinel lymph nodes for real-time image-guided surgery. Theranostics. 2014; 4(7):693-700. PMID: 24883119.
    Citations: 14     Fields:    Translation:Animals
  37. Verbeek FP, Schaafsma BE, Tummers QR, van der Vorst JR, van der Made WJ, Baeten CI, Bonsing BA, Frangioni JV, van de Velde CJ, Vahrmeijer AL, Swijnenburg RJ. Optimization of near-infrared fluorescence cholangiography for open and laparoscopic surgery. Surg Endosc. 2014 Apr; 28(4):1076-82. PMID: 24232054.
    Citations: 26     Fields:    Translation:Humans
  38. Tummers QR, Verbeek FP, Schaafsma BE, Boonstra MC, van der Vorst JR, Liefers GJ, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Real-time intraoperative detection of breast cancer using near-infrared fluorescence imaging and Methylene Blue. Eur J Surg Oncol. 2014 Jul; 40(7):850-8. PMID: 24862545.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  39. Verbeek FP, van der Vorst JR, Tummers QR, Boonstra MC, de Rooij KE, Löwik CW, Valentijn AR, van de Velde CJ, Choi HS, Frangioni JV, Vahrmeijer AL. Near-infrared fluorescence imaging of both colorectal cancer and ureters using a low-dose integrin targeted probe. Ann Surg Oncol. 2014 Dec; 21 Suppl 4:S528-37. PMID: 24515567.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  40. Hyun H, Owens EA, Narayana L, Wada H, Gravier J, Bao K, Frangioni JV, Choi HS, Henary M. Central C-C Bonding Increases Optical and Chemical Stability of NIR Fluorophores. RSC Adv. 2014 Jan 01; 4(102):58762-58768. PMID: 25530846.
    Citations: 5     
  41. Verbeek FP, Troyan SL, Mieog JS, Liefers GJ, Moffitt LA, Rosenberg M, Hirshfield-Bartek J, Gioux S, van de Velde CJ, Vahrmeijer AL, Frangioni JV. Near-infrared fluorescence sentinel lymph node mapping in breast cancer: a multicenter experience. Breast Cancer Res Treat. 2014 Jan; 143(2):333-42. PMID: 24337507.
    Citations: 38     Fields:    Translation:Humans
  42. van Driel PB, van der Vorst JR, Verbeek FP, Oliveira S, Snoeks TJ, Keereweer S, Chan B, Boonstra MC, Frangioni JV, van Bergen en Henegouwen PM, Vahrmeijer AL, Lowik CW. Intraoperative fluorescence delineation of head and neck cancer with a fluorescent anti-epidermal growth factor receptor nanobody. Int J Cancer. 2014 Jun 01; 134(11):2663-73. PMID: 24222574.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  43. Venugopal V, Park M, Ashitate Y, Neacsu F, Kettenring F, Frangioni JV, Gangadharan SP, Gioux S. Design and characterization of an optimized simultaneous color and near-infrared fluorescence rigid endoscopic imaging system. J Biomed Opt. 2013 Dec; 18(12):126018. PMID: 24362927.
    Citations: 7     Fields:    Translation:Animals
  44. van der Vorst JR, Schaafsma BE, Verbeek FP, Swijnenburg RJ, Tummers QR, Hutteman M, Hamming JF, Kievit J, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Intraoperative near-infrared fluorescence imaging of parathyroid adenomas with use of low-dose methylene blue. Head Neck. 2014 Jun; 36(6):853-8. PMID: 23720199.
    Citations: 15     Fields:    Translation:Humans
  45. Gibbs SL, Xie Y, Goodwill HL, Nasr KA, Ashitate Y, Madigan VJ, Siclovan TM, Zavodszky M, Tan Hehir CA, Frangioni JV. Structure-activity relationship of nerve-highlighting fluorophores. PLoS One. 2013; 8(9):e73493. PMID: 24039960.
    Citations: 8     Fields:    Translation:HumansAnimals
  46. Nguyen JT, Lin SJ, Tobias AM, Gioux S, Mazhar A, Cuccia DJ, Ashitate Y, Stockdale A, Oketokoun R, Durr NJ, Moffitt LA, Durkin AJ, Tromberg BJ, Frangioni JV, Lee BT. A novel pilot study using spatial frequency domain imaging to assess oxygenation of perforator flaps during reconstructive breast surgery. Ann Plast Surg. 2013 Sep; 71(3):308-15. PMID: 23945533.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  47. Vahrmeijer AL, Hutteman M, van der Vorst JR, van de Velde CJ, Frangioni JV. Image-guided cancer surgery using near-infrared fluorescence. Nat Rev Clin Oncol. 2013 Sep; 10(9):507-18. PMID: 23881033.
    Citations: 160     Fields:    Translation:HumansAnimals
  48. van der Vorst JR, Schaafsma BE, Hutteman M, Verbeek FP, Liefers GJ, Hartgrink HH, Smit VT, Löwik CW, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Near-infrared fluorescence-guided resection of colorectal liver metastases. Cancer. 2013 Sep 15; 119(18):3411-8. PMID: 23794086.
    Citations: 59     Fields:    Translation:HumansCTClinical Trials
  49. Gilmore DM, Khullar OV, Jaklitsch MT, Chirieac LR, Frangioni JV, Colson YL. Identification of metastatic nodal disease in a phase 1 dose-escalation trial of intraoperative sentinel lymph node mapping in non-small cell lung cancer using near-infrared imaging. J Thorac Cardiovasc Surg. 2013 Sep; 146(3):562-70; discussion 569-70. PMID: 23790404.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  50. Schaafsma BE, Verbeek FP, Rietbergen DD, van der Hiel B, van der Vorst JR, Liefers GJ, Frangioni JV, van de Velde CJ, van Leeuwen FW, Vahrmeijer AL. Clinical trial of combined radio- and fluorescence-guided sentinel lymph node biopsy in breast cancer. Br J Surg. 2013 Jul; 100(8):1037-44. PMID: 23696463.
    Citations: 30     Fields:    Translation:Humans
  51. Nguyen JT, Ashitate Y, Venugopal V, Neacsu F, Kettenring F, Frangioni JV, Gioux S, Lee BT. Near-infrared imaging of face transplants: are both pedicles necessary? J Surg Res. 2013 Sep; 184(1):714-21. PMID: 23706565.
    Citations: 3     Fields:    Translation:Animals
  52. Lee JH, Park S, Hyun H, Bordo MW, Oketokoun R, Nasr KA, Frangioni JV, Choi HS. High-throughput screening of small molecule ligands targeted to live bacteria surface. Anal Chem. 2013 Apr 02; 85(7):3508-14. PMID: 23461528.
    Citations: 3     Fields:    Translation:HumansCells
  53. Ashitate Y, Lee BT, Laurence RG, Lunsford E, Hutteman M, Oketokoun R, Choi HS, Frangioni JV. Intraoperative prediction of postoperative flap outcome using the near-infrared fluorophore methylene blue. Ann Plast Surg. 2013 Mar; 70(3):360-5. PMID: 22395044.
    Citations: 4     Fields:    Translation:Animals
  54. Verbeek FP, van der Vorst JR, Schaafsma BE, Swijnenburg RJ, Gaarenstroom KN, Elzevier HW, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Intraoperative near infrared fluorescence guided identification of the ureters using low dose methylene blue: a first in human experience. J Urol. 2013 Aug; 190(2):574-9. PMID: 23466242.
    Citations: 16     Fields:    Translation:Humans
  55. Gilmore DM, Khullar OV, Gioux S, Stockdale A, Frangioni JV, Colson YL, Russell SE. Effective low-dose escalation of indocyanine green for near-infrared fluorescent sentinel lymph node mapping in melanoma. Ann Surg Oncol. 2013 Jul; 20(7):2357-63. PMID: 23440551.
    Citations: 19     Fields:    Translation:HumansCTClinical Trials
  56. Schaafsma BE, Verbeek FP, Peters AA, van der Vorst JR, de Kroon CD, van Poelgeest MI, Trimbos JB, van de Velde CJ, Frangioni JV, Vahrmeijer AL, Gaarenstroom KN. Near-infrared fluorescence sentinel lymph node biopsy in vulvar cancer: a randomised comparison of lymphatic tracers. BJOG. 2013 May; 120(6):758-64. PMID: 23418877.
    Citations: 9     Fields:    Translation:Humans
  57. Ashitate Y, Lee BT, Ngo LH, Laurence RG, Hutteman M, Oketokoun R, Lunsford E, Soo Choi H, Frangioni JV. Quantitative assessment of nipple perfusion with near-infrared fluorescence imaging. Ann Plast Surg. 2013 Feb; 70(2):149-53. PMID: 21862913.
    Citations: 4     Fields:    Translation:Animals
  58. Schaafsma BE, Verbeek FP, van der Vorst JR, Hutteman M, Kuppen PJ, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Ex vivo sentinel node mapping in colon cancer combining blue dye staining and fluorescence imaging. J Surg Res. 2013 Jul; 183(1):253-7. PMID: 23391167.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  59. Choi HS, Gibbs SL, Lee JH, Kim SH, Ashitate Y, Liu F, Hyun H, Park G, Xie Y, Bae S, Henary M, Frangioni JV. Targeted zwitterionic near-infrared fluorophores for improved optical imaging. Nat Biotechnol. 2013 Feb; 31(2):148-53. PMID: 23292608.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  60. van der Vorst JR, Schaafsma BE, Verbeek FP, Swijnenburg RJ, Hutteman M, Liefers GJ, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Dose optimization for near-infrared fluorescence sentinel lymph node mapping in patients with melanoma. Br J Dermatol. 2013 Jan; 168(1):93-8. PMID: 23078649.
    Citations: 19     Fields:    Translation:Humans
  61. Verbeek FP, van der Vorst JR, Schaafsma BE, Hutteman M, Bonsing BA, van Leeuwen FW, Frangioni JV, van de Velde CJ, Swijnenburg RJ, Vahrmeijer AL. Image-guided hepatopancreatobiliary surgery using near-infrared fluorescent light. J Hepatobiliary Pancreat Sci. 2012 Nov; 19(6):626-37. PMID: 22790312.
    Citations: 26     Fields:    Translation:Humans
  62. Hyun H, Bordo MW, Nasr K, Feith D, Lee JH, Kim SH, Ashitate Y, Moffitt LA, Rosenberg M, Henary M, Choi HS, Frangioni JV. cGMP-Compatible preparative scale synthesis of near-infrared fluorophores. Contrast Media Mol Imaging. 2012 Nov-Dec; 7(6):516-24. PMID: 22991318.
    Citations: 17     Fields:    Translation:Animals
  63. Frangioni JV. Nonprofit foundations for open-source biomedical technology development. Nat Biotechnol. 2012 Oct; 30(10):928-32. PMID: 23051807.
    Citations:    Fields:    Translation:Humans
  64. van der Vorst JR, Schaafsma BE, Verbeek FP, Keereweer S, Jansen JC, van der Velden LA, Langeveld AP, Hutteman M, Löwik CW, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Near-infrared fluorescence sentinel lymph node mapping of the oral cavity in head and neck cancer patients. Oral Oncol. 2013 Jan; 49(1):15-9. PMID: 22939692.
    Citations: 23     Fields:    Translation:Humans
  65. van der Vorst JR, Vahrmeijer AL, Hutteman M, Bosse T, Smit VT, van de Velde CJ, Frangioni JV, Bonsing BA. Near-infrared fluorescence imaging of a solitary fibrous tumor of the pancreas using methylene blue. World J Gastrointest Surg. 2012 Jul 27; 4(7):180-4. PMID: 22905287.
    Citations: 16     
  66. Schaafsma BE, van der Vorst JR, Gaarenstroom KN, Peters AA, Verbeek FP, de Kroon CD, Trimbos JB, van Poelgeest MI, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Randomized comparison of near-infrared fluorescence lymphatic tracers for sentinel lymph node mapping of cervical cancer. Gynecol Oncol. 2012 Oct; 127(1):126-30. PMID: 22796548.
    Citations: 24     Fields:    Translation:Humans
  67. Bhatia S, Frangioni JV, Hoffman RM, Iafrate AJ, Polyak K. The challenges posed by cancer heterogeneity. Nat Biotechnol. 2012 Jul 10; 30(7):604-10. PMID: 22781679.
    Citations: 29     Fields:    Translation:HumansCells
  68. van der Vorst JR, Schaafsma BE, Verbeek FP, Hutteman M, Mieog JS, Lowik CW, Liefers GJ, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Randomized comparison of near-infrared fluorescence imaging using indocyanine green and 99(m) technetium with or without patent blue for the sentinel lymph node procedure in breast cancer patients. Ann Surg Oncol. 2012 Dec; 19(13):4104-11. PMID: 22752379.
    Citations: 31     Fields:    Translation:HumansCTClinical Trials
  69. Ashitate Y, Vooght CS, Hutteman M, Oketokoun R, Choi HS, Frangioni JV. Simultaneous assessment of luminal integrity and vascular perfusion of the gastrointestinal tract using dual-channel near-infrared fluorescence. Mol Imaging. 2012 Jul-Aug; 11(4):301-8. PMID: 22954146.
    Citations: 5     Fields:    Translation:Animals
  70. Liu F, Lunsford EP, Tong J, Ashitate Y, Gibbs SL, Yu J, Choi HS, Henske EP, Frangioni JV. Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex. PLoS One. 2012; 7(6):e38589. PMID: 22719903.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  71. Nguyen JT, Ashitate Y, Buchanan IA, Ibrahim AM, Gioux S, Patel PP, Frangioni JV, Lee BT. Bone flap perfusion assessment using near-infrared fluorescence imaging. J Surg Res. 2012 Dec; 178(2):e43-50. PMID: 22664132.
    Citations: 6     Fields:    Translation:Animals
  72. Nguyen JT, Ashitate Y, Buchanan IA, Ibrahim AM, Gioux S, Patel PP, Frangioni JV, Lee BT. Face transplant perfusion assessment using near-infrared fluorescence imaging. J Surg Res. 2012 Oct; 177(2):e83-8. PMID: 22572616.
    Citations: 4     Fields:    Translation:Animals
  73. Ashitate Y, Kim SH, Tanaka E, Henary M, Choi HS, Frangioni JV, Flaumenhaft R. Two-wavelength near-infrared fluorescence for the quantitation of drug antiplatelet effects in large animal model systems. J Vasc Surg. 2012 Jul; 56(1):171-80. PMID: 22503225.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  74. Orcutt KD, Rhoden JJ, Ruiz-Yi B, Frangioni JV, Wittrup KD. Effect of small-molecule-binding affinity on tumor uptake in vivo: a systematic study using a pretargeted bispecific antibody. Mol Cancer Ther. 2012 Jun; 11(6):1365-72. PMID: 22491799.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  75. Fujii H, Idoine JD, Gioux S, Accorsi R, Slochower DR, Lanza RC, Frangioni JV. Optimization of coded aperture radioscintigraphy for sentinel lymph node mapping. Mol Imaging Biol. 2012 Apr; 14(2):173-82. PMID: 21567254.
    Citations:    Fields:    Translation:HumansAnimals
  76. Khurd P, Grady L, Oketokoun R, Sundar H, Gajera T, Gibbs-Strauss S, Frangioni JV, Kamen A. Global error minimization in image mosaicing using graph connectivity and its applications in microscopy. J Pathol Inform. 2011; 2:S8. PMID: 22811964.
    Citations: 1     
  77. Khullar OV, Griset AP, Gibbs-Strauss SL, Chirieac LR, Zubris KA, Frangioni JV, Grinstaff MW, Colson YL. Nanoparticle migration and delivery of Paclitaxel to regional lymph nodes in a large animal model. J Am Coll Surg. 2012 Mar; 214(3):328-37. PMID: 22225645.
    Citations: 9     Fields:    Translation:Animals
  78. Inoue K, Liu F, Hoppin J, Lunsford EP, Lackas C, Hesterman J, Lenkinski RE, Fujii H, Frangioni JV. High-resolution Computed Tomography Of Single Breast Cancer Microcalcifications In Vivo. Mol Imaging. 2012; 11(0):1-10. PMID: 22480825.
    Citations:    
  79. Lee JH, Hyun H, Cross CJ, Henary M, Nasr KA, Oketokoun R, Choi HS, Frangioni JV. Rapid and Facile Microwave-Assisted Surface Chemistry for Functionalized Microarray Slides. Adv Funct Mater. 2012 Feb 22; 22(4):872-878. PMID: 23467787.
    Citations: 2     
  80. van der Vorst JR, Hutteman M, Gaarenstroom KN, Peters AA, Mieog JS, Schaafsma BE, Kuppen PJ, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Optimization of near-infrared fluorescent sentinel lymph node mapping in cervical cancer patients. Int J Gynecol Cancer. 2011 Nov; 21(8):1472-8. PMID: 22027751.
    Citations: 28     Fields:    Translation:Humans
  81. Matsui A, Winer JH, Laurence RG, Frangioni JV. Predicting the survival of experimental ischaemic small bowel using intraoperative near-infrared fluorescence angiography. Br J Surg. 2011 Dec; 98(12):1725-34. PMID: 21953541.
    Citations: 8     Fields:    Translation:Animals
  82. Gioux S, Mazhar A, Lee BT, Lin SJ, Tobias AM, Cuccia DJ, Stockdale A, Oketokoun R, Ashitate Y, Kelly E, Weinmann M, Durr NJ, Moffitt LA, Durkin AJ, Tromberg BJ, Frangioni JV. First-in-human pilot study of a spatial frequency domain oxygenation imaging system. J Biomed Opt. 2011 Aug; 16(8):086015. PMID: 21895327.
    Citations: 28     Fields:    Translation:HumansAnimals
  83. Hutteman M, van der Vorst JR, Gaarenstroom KN, Peters AA, Mieog JS, Schaafsma BE, Löwik CW, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Optimization of near-infrared fluorescent sentinel lymph node mapping for vulvar cancer. Am J Obstet Gynecol. 2012 Jan; 206(1):89.e1-5. PMID: 21963099.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  84. Ashitate Y, Stockdale A, Choi HS, Laurence RG, Frangioni JV. Real-time simultaneous near-infrared fluorescence imaging of bile duct and arterial anatomy. J Surg Res. 2012 Jul; 176(1):7-13. PMID: 21816414.
    Citations: 22     Fields:    Translation:Animals
  85. Hutteman M, van der Vorst JR, Mieog JS, Bonsing BA, Hartgrink HH, Kuppen PJ, Löwik CW, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Near-infrared fluorescence imaging in patients undergoing pancreaticoduodenectomy. Eur Surg Res. 2011; 47(2):90-7. PMID: 21720166.
    Citations: 24     Fields:    Translation:HumansCTClinical Trials
  86. Lee JH, Choi HS, Nasr KA, Ha M, Kim Y, Frangioni JV. High-throughput small molecule identification using MALDI-TOF and a nanolayered substrate. Anal Chem. 2011 Jul 01; 83(13):5283-9. PMID: 21651231.
    Citations: 2     Fields:    Translation:Cells
  87. Choi HS, Nasr K, Alyabyev S, Feith D, Lee JH, Kim SH, Ashitate Y, Hyun H, Patonay G, Strekowski L, Henary M, Frangioni JV. Synthesis and in vivo fate of zwitterionic near-infrared fluorophores. Angew Chem Int Ed Engl. 2011 Jul 04; 50(28):6258-63. PMID: 21656624.
    Citations: 71     Fields:    Translation:Animals
  88. Schaafsma BE, Mieog JS, Hutteman M, van der Vorst JR, Kuppen PJ, Löwik CW, Frangioni JV, van de Velde CJ, Vahrmeijer AL. The clinical use of indocyanine green as a near-infrared fluorescent contrast agent for image-guided oncologic surgery. J Surg Oncol. 2011 Sep 01; 104(3):323-32. PMID: 21495033.
    Citations: 146     Fields:    Translation:Humans
  89. Vahrmeijer AL, Frangioni JV. Seeing the invisible during surgery. Br J Surg. 2011 Jun; 98(6):749-50. PMID: 21484776.
    Citations: 12     Fields:    Translation:Humans
  90. Ashitate Y, Tanaka E, Stockdale A, Choi HS, Frangioni JV. Near-infrared fluorescence imaging of thoracic duct anatomy and function in open surgery and video-assisted thoracic surgery. J Thorac Cardiovasc Surg. 2011 Jul; 142(1):31-8.e1-2. PMID: 21477818.
    Citations: 16     Fields:    Translation:Animals
  91. Frangioni JV. The myth of multimodality diagnostic agents. Mol Imaging. 2011 Apr; 10(2):79-80. PMID: 21439252.
    Citations:    Fields:    Translation:Humans
  92. Gibbs-Strauss SL, Nasr KA, Fish KM, Khullar O, Ashitate Y, Siclovan TM, Johnson BF, Barnhardt NE, Tan Hehir CA, Frangioni JV. Nerve-highlighting fluorescent contrast agents for image-guided surgery. Mol Imaging. 2011 Apr; 10(2):91-101. PMID: 21439254.
    Citations: 36     Fields:    Translation:Animals
  93. Orcutt KD, Nasr KA, Whitehead DG, Frangioni JV, Wittrup KD. Biodistribution and clearance of small molecule hapten chelates for pretargeted radioimmunotherapy. Mol Imaging Biol. 2011 Apr; 13(2):215-21. PMID: 20533093.
    Citations: 8     Fields:    Translation:Animals
  94. Inoue K, Liu F, Hoppin J, Lunsford EP, Lackas C, Hesterman J, Lenkinski RE, Fujii H, Frangioni JV. High-resolution computed tomography of single breast cancer microcalcifications in vivo. Mol Imaging. 2011 Aug; 10(4):295-304. PMID: 21504703.
    Citations: 2     Fields:    Translation:HumansAnimals
  95. Mieog JS, Troyan SL, Hutteman M, Donohoe KJ, van der Vorst JR, Stockdale A, Liefers GJ, Choi HS, Gibbs-Strauss SL, Putter H, Gioux S, Kuppen PJ, Ashitate Y, Löwik CW, Smit VT, Oketokoun R, Ngo LH, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Toward optimization of imaging system and lymphatic tracer for near-infrared fluorescent sentinel lymph node mapping in breast cancer. Ann Surg Oncol. 2011 Sep; 18(9):2483-91. PMID: 21360250.
    Citations: 83     Fields:    Translation:HumansAnimals
  96. Hutteman M, Mieog JS, van der Vorst JR, Liefers GJ, Putter H, Löwik CW, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Randomized, double-blind comparison of indocyanine green with or without albumin premixing for near-infrared fluorescence imaging of sentinel lymph nodes in breast cancer patients. Breast Cancer Res Treat. 2011 May; 127(1):163-70. PMID: 21360075.
    Citations: 32     Fields:    Translation:HumansCTClinical Trials
  97. van der Vorst JR, Hutteman M, Mieog JS, de Rooij KE, Kaijzel EL, Löwik CW, Putter H, Kuppen PJ, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Near-infrared fluorescence imaging of liver metastases in rats using indocyanine green. J Surg Res. 2012 May 15; 174(2):266-71. PMID: 21396660.
    Citations: 13     Fields:    Translation:AnimalsCells
  98. Choi HS, Frangioni JV. Nanoparticles for biomedical imaging: fundamentals of clinical translation. Mol Imaging. 2010 Dec; 9(6):291-310. PMID: 21084027.
    Citations: 67     Fields:    Translation:Humans
  99. Hutteman M, Choi HS, Mieog JS, van der Vorst JR, Ashitate Y, Kuppen PJ, van Groningen MC, Löwik CW, Smit VT, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Clinical translation of ex vivo sentinel lymph node mapping for colorectal cancer using invisible near-infrared fluorescence light. Ann Surg Oncol. 2011 Apr; 18(4):1006-14. PMID: 21080086.
    Citations: 24     Fields:    Translation:HumansAnimals
  100. Choi HS, Ashitate Y, Lee JH, Kim SH, Matsui A, Insin N, Bawendi MG, Semmler-Behnke M, Frangioni JV, Tsuda A. Rapid translocation of nanoparticles from the lung airspaces to the body. Nat Biotechnol. 2010 Dec; 28(12):1300-3. PMID: 21057497.
    Citations: 131     Fields:    Translation:Animals
  101. Matsui A, Lee BT, Winer JH, Laurence RG, Frangioni JV. Predictive capability of near-infrared fluorescence angiography in submental perforator flap survival. Plast Reconstr Surg. 2010 Nov; 126(5):1518-27. PMID: 21042109.
    Citations: 13     Fields:    Translation:Animals
  102. Lee BT, Hutteman M, Gioux S, Stockdale A, Lin SJ, Ngo LH, Frangioni JV. The FLARE intraoperative near-infrared fluorescence imaging system: a first-in-human clinical trial in perforator flap breast reconstruction. Plast Reconstr Surg. 2010 Nov; 126(5):1472-81. PMID: 21042103.
    Citations: 37     Fields:    Translation:HumansCTClinical Trials
  103. Mazhar A, Dell S, Cuccia DJ, Gioux S, Durkin AJ, Frangioni JV, Tromberg BJ. Wavelength optimization for rapid chromophore mapping using spatial frequency domain imaging. J Biomed Opt. 2010 Nov-Dec; 15(6):061716. PMID: 21198164.
    Citations: 25     Fields:    Translation:Humans
  104. Orcutt KD, Slusarczyk AL, Cieslewicz M, Ruiz-Yi B, Bhushan KR, Frangioni JV, Wittrup KD. Engineering an antibody with picomolar affinity to DOTA chelates of multiple radionuclides for pretargeted radioimmunotherapy and imaging. Nucl Med Biol. 2011 Feb; 38(2):223-33. PMID: 21315278.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  105. Gioux S, Choi HS, Frangioni JV. Image-guided surgery using invisible near-infrared light: fundamentals of clinical translation. Mol Imaging. 2010 Oct; 9(5):237-55. PMID: 20868625.
    Citations: 126     Fields:    Translation:Humans
  106. Zubris KA, Khullar OV, Griset AP, Gibbs-Strauss S, Frangioni JV, Colson YL, Grinstaff MW. Ease of synthesis, controllable sizes, and in vivo large-animal-lymph migration of polymeric nanoparticles. ChemMedChem. 2010 Sep 03; 5(9):1435-8. PMID: 20593440.
    Citations: 6     Fields:    Translation:Animals
  107. Schulz MD, Khullar O, Frangioni JV, Grinstaff MW, Colson YL. Nanotechnology in thoracic surgery. Ann Thorac Surg. 2010 Jun; 89(6):S2188-90. PMID: 20494008.
    Citations: 2     Fields:    Translation:HumansAnimals
  108. Gibbs-Strauss SL, Vooght C, Fish KM, Nasr KA, Siclovan TM, Barnhardt NE, Tan Hehir CA, Frangioni JV. Molecular imaging agents specific for the annulus fibrosus of the intervertebral disk. Mol Imaging. 2010 Jun; 9(3):128-40. PMID: 20487679.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  109. Khurd P, Bahlmann C, Maday P, Kamen A, Gibbs-Strauss S, Genega EM, Frangioni JV. COMPUTER-AIDED GLEASON GRADING OF PROSTATE CANCER HISTOPATHOLOGICAL IMAGES USING TEXTON FORESTS. Proc IEEE Int Symp Biomed Imaging. 2010 Apr 17; 14-17 April 2010:636-639. PMID: 21221421.
    Citations: 9     
  110. Gioux S, Lomnes SJ, Choi HS, Frangioni JV. Low-frequency wide-field fluorescence lifetime imaging using a high-power near-infrared light-emitting diode light source. J Biomed Opt. 2010 Mar-Apr; 15(2):026005. PMID: 20459250.
    Citations: 7     Fields:    
  111. Matsui A, Tanaka E, Choi HS, Winer JH, Kianzad V, Gioux S, Laurence RG, Frangioni JV. Real-time intra-operative near-infrared fluorescence identification of the extrahepatic bile ducts using clinically available contrast agents. Surgery. 2010 Jul; 148(1):87-95. PMID: 20117813.
    Citations: 37     Fields:    Translation:Animals
  112. Matsui A, Tanaka E, Choi HS, Kianzad V, Gioux S, Lomnes SJ, Frangioni JV. Real-time, near-infrared, fluorescence-guided identification of the ureters using methylene blue. Surgery. 2010 Jul; 148(1):78-86. PMID: 20117811.
    Citations: 27     Fields:    Translation:Animals
  113. Mazhar A, Cuccia DJ, Gioux S, Durkin AJ, Frangioni JV, Tromberg BJ. Structured illumination enhances resolution and contrast in thick tissue fluorescence imaging. J Biomed Opt. 2010 Jan-Feb; 15(1):010506. PMID: 20210421.
    Citations: 19     Fields:    
  114. Winer JH, Choi HS, Gibbs-Strauss SL, Ashitate Y, Colson YL, Frangioni JV. Intraoperative localization of insulinoma and normal pancreas using invisible near-infrared fluorescent light. Ann Surg Oncol. 2010 Apr; 17(4):1094-100. PMID: 20033320.
    Citations: 23     Fields:    Translation:Animals
  115. Lee BT, Matsui A, Hutteman M, Lin SJ, Winer JH, Laurence RG, Frangioni JV. Intraoperative near-infrared fluorescence imaging in perforator flap reconstruction: current research and early clinical experience. J Reconstr Microsurg. 2010 Jan; 26(1):59-65. PMID: 20027541.
    Citations: 28     Fields:    Translation:HumansAnimalsCTClinical Trials
  116. Orcutt KD, Ackerman ME, Cieslewicz M, Quiroz E, Slusarczyk AL, Frangioni JV, Wittrup KD. A modular IgG-scFv bispecific antibody topology. Protein Eng Des Sel. 2010 Apr; 23(4):221-8. PMID: 20019028.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  117. Kesavan K, Ratliff J, Johnson EW, Dahlberg W, Asara JM, Misra P, Frangioni JV, Jacoby DB. Annexin A2 is a molecular target for TM601, a peptide with tumor-targeting and anti-angiogenic effects. J Biol Chem. 2010 Feb 12; 285(7):4366-74. PMID: 20018898.
    Citations: 42     Fields:    Translation:HumansCells
  118. Frangioni JV. The problem is background, not signal. Mol Imaging. 2009 Dec; 8(6):303-4. PMID: 20003888.
    Citations: 13     Fields:    Translation:Humans
  119. Choi HS, Liu W, Liu F, Nasr K, Misra P, Bawendi MG, Frangioni JV. Design considerations for tumour-targeted nanoparticles. Nat Nanotechnol. 2010 Jan; 5(1):42-7. PMID: 19893516.
    Citations: 154     Fields:    Translation:HumansAnimalsCells
  120. Gioux S, Ashitate Y, Hutteman M, Frangioni JV. Motion-gated acquisition for in vivo optical imaging. J Biomed Opt. 2009 Nov-Dec; 14(6):064038. PMID: 20059276.
    Citations: 9     Fields:    Translation:Animals
  121. Matsui A, Lee BT, Winer JH, Laurence RG, Frangioni JV. Submental perforator flap design with a near-infrared fluorescence imaging system: the relationship among number of perforators, flap perfusion, and venous drainage. Plast Reconstr Surg. 2009 Oct; 124(4):1098-104. PMID: 19935293.
    Citations: 14     Fields:    Translation:Animals
  122. Liu F, Misra P, Lunsford EP, Vannah JT, Liu Y, Lenkinski RE, Frangioni JV. A dose- and time-controllable syngeneic animal model of breast cancer microcalcification. Breast Cancer Res Treat. 2010 Jul; 122(1):87-94. PMID: 19760034.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  123. Matsui A, Lee BT, Winer JH, Kianzad V, Frangioni JV. Image-guided perforator flap design using invisible near-infrared light and validation with x-ray angiography. Ann Plast Surg. 2009 Sep; 63(3):327-30. PMID: 19692894.
    Citations: 14     Fields:    Translation:Animals
  124. Ly HQ, Hoshino K, Pomerantseva I, Kawase Y, Yoneyama R, Takewa Y, Fortier A, Gibbs-Strauss SL, Vooght C, Frangioni JV, Hajjar RJ. In vivo myocardial distribution of multipotent progenitor cells following intracoronary delivery in a swine model of myocardial infarction. Eur Heart J. 2009 Dec; 30(23):2861-8. PMID: 19687154.
    Citations: 14     Fields:    Translation:AnimalsCells
  125. Matsui A, Lee BT, Winer JH, Laurence RG, Frangioni JV. Quantitative assessment of perfusion and vascular compromise in perforator flaps using a near-infrared fluorescence-guided imaging system. Plast Reconstr Surg. 2009 Aug; 124(2):451-60. PMID: 19644259.
    Citations: 24     Fields:    Translation:Animals
  126. Kajimura S, Seale P, Kubota K, Lunsford E, Frangioni JV, Gygi SP, Spiegelman BM. Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex. Nature. 2009 Aug 27; 460(7259):1154-8. PMID: 19641492.
    Citations: 224     Fields:    Translation:HumansAnimalsCells
  127. Troyan SL, Kianzad V, Gibbs-Strauss SL, Gioux S, Matsui A, Oketokoun R, Ngo L, Khamene A, Azar F, Frangioni JV. The FLARE intraoperative near-infrared fluorescence imaging system: a first-in-human clinical trial in breast cancer sentinel lymph node mapping. Ann Surg Oncol. 2009 Oct; 16(10):2943-52. PMID: 19582506.
    Citations: 196     Fields:    Translation:HumansAnimalsCTClinical Trials
  128. Tanaka E, Chen FY, Flaumenhaft R, Graham GJ, Laurence RG, Frangioni JV. Real-time assessment of cardiac perfusion, coronary angiography, and acute intravascular thrombi using dual-channel near-infrared fluorescence imaging. J Thorac Cardiovasc Surg. 2009 Jul; 138(1):133-40. PMID: 19577070.
    Citations: 24     Fields:    Translation:Animals
  129. Choi HS, Ipe BI, Misra P, Lee JH, Bawendi MG, Frangioni JV. Tissue- and organ-selective biodistribution of NIR fluorescent quantum dots. Nano Lett. 2009 Jun; 9(6):2354-9. PMID: 19422261.
    Citations: 63     Fields:    Translation:Animals
  130. Troyan S, Gibbs-Strauss S, Gioux S, Oketokoun R, Azar F, Khamene A, Kianzad V, Rosenberg M, Clough BL, Frangioni JV. Image-guided near-infrared fluorescent sentinel lymph node mapping in human breast cancer. J Clin Oncol. 2009 May 20; 27(15_suppl):e11591. PMID: 27964225.
    Citations:    
  131. Gioux S, Mazhar A, Cuccia DJ, Durkin AJ, Tromberg BJ, Frangioni JV. Three-dimensional surface profile intensity correction for spatially modulated imaging. J Biomed Opt. 2009 May-Jun; 14(3):034045. PMID: 19566337.
    Citations: 44     Fields:    Translation:HumansCells
  132. Gioux S, Kianzad V, Ciocan R, Gupta S, Oketokoun R, Frangioni JV. High-power, computer-controlled, light-emitting diode-based light sources for fluorescence imaging and image-guided surgery. Mol Imaging. 2009 May-Jun; 8(3):156-65. PMID: 19723473.
    Citations: 33     Fields:    Translation:Animals
  133. Ciocan R, Lenkinski RE, Bernstein J, Bancu M, Marquis R, Ivanishev A, Kourtelidis F, Matsui A, Borenstein J, Frangioni JV. MRI contrast using solid-state, B1-distorting, microelectromechanical systems (MEMS) microresonant devices (MRDs). Magn Reson Med. 2009 Apr; 61(4):860-6. PMID: 19189289.
    Citations: 2     Fields:    Translation:Animals
  134. Matsui A, Lomnes SJ, Frangioni JV. Optical clearing of the skin for near-infrared fluorescence image-guided surgery. J Biomed Opt. 2009 Mar-Apr; 14(2):024019. PMID: 19405749.
    Citations: 2     Fields:    Translation:Animals
  135. Matsui A, Lee BT, Winer JH, Vooght CS, Laurence RG, Frangioni JV. Real-time intraoperative near-infrared fluorescence angiography for perforator identification and flap design. Plast Reconstr Surg. 2009 Mar; 123(3):125e-7e. PMID: 19319038.
    Citations: 22     Fields:    Translation:Animals
  136. Humblet V, Misra P, Bhushan KR, Nasr K, Ko YS, Tsukamoto T, Pannier N, Frangioni JV, Maison W. Multivalent scaffolds for affinity maturation of small molecule cell surface binders and their application to prostate tumor targeting. J Med Chem. 2009 Jan 22; 52(2):544-50. PMID: 19108655.
    Citations: 11