Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Geicho Nakatsu, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Cao L, Wang S, Zhang Y, Wong KC, Nakatsu G, Wang X, Wong S, Ji J, Yu J. Correction to: Zinc-finger protein 471 suppresses gastric cancer through transcriptionally repressing downstream oncogenic PLS3 and TFAP2A. Oncogene. 2022 Jun; 41(23):3298-3299. PMID: 35484334.
    Citations:    Fields:    
  2. Sugimura N, Li Q, Chu ESH, Lau HCH, Fong W, Liu W, Liang C, Nakatsu G, Su ACY, Coker OO, Wu WKK, Chan FKL, Yu J. Lactobacillus gallinarum modulates the gut microbiota and produces anti-cancer metabolites to protect against colorectal tumourigenesis. Gut. 2021 Dec 22. PMID: 34937766; PMCID: PMC9484392.
    Citations: 6     Fields:    
  3. Nakatsu G. Toward a postbiotic era of microbiome science: Opportunities to advance immunotherapies for hepatocellular carcinoma. J Gastroenterol Hepatol. 2022 Jan; 37(1):34-38. PMID: 34665475.
    Citations:    Fields:    Translation:Humans
  4. Brennan CA, Nakatsu G, Gallini Comeau CA, Drew DA, Glickman JN, Schoen RE, Chan AT, Garrett WS. Aspirin Modulation of the Colorectal Cancer-Associated Microbe Fusobacterium nucleatum. mBio. 2021 04 06; 12(2). PMID: 33824205.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  5. Watanabe T, Nadatani Y, Suda W, Higashimori A, Otani K, Fukunaga S, Hosomi S, Tanaka F, Nagami Y, Taira K, Tanigawa T, Nakatsu G, Hattori M, Fujiwara Y. Long-term persistence of gastric dysbiosis after eradication of Helicobacter pylori in patients who underwent endoscopic submucosal dissection for early gastric cancer. Gastric Cancer. 2021 May; 24(3):710-720. PMID: 33201352.
    Citations: 6     Fields:    Translation:HumansCells
  6. Xia X, Wu WKK, Wong SH, Liu D, Kwong TNY, Nakatsu G, Yan PS, Chuang YM, Chan MW, Coker OO, Chen Z, Yeoh YK, Zhao L, Wang X, Cheng WY, Chan MTV, Chan PKS, Sung JJY, Wang MH, Yu J. Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer. Microbiome. 2020 07 16; 8(1):108. PMID: 32678024; PMCID: PMC7367367.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  7. Zhao R, Coker OO, Wu J, Zhou Y, Zhao L, Nakatsu G, Bian X, Wei H, Chan AWH, Sung JJY, Chan FKL, El-Omar E, Yu J. Aspirin Reduces Colorectal Tumor Development in Mice and Gut Microbes Reduce its Bioavailability and Chemopreventive Effects. Gastroenterology. 2020 09; 159(3):969-983.e4. PMID: 32387495.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  8. Liang JQ, Li T, Nakatsu G, Chen YX, Yau TO, Chu E, Wong S, Szeto CH, Ng SC, Chan FKL, Fang JY, Sung JJY, Yu J. A novel faecal Lachnoclostridium marker for the non-invasive diagnosis of colorectal adenoma and cancer. Gut. 2020 07; 69(7):1248-1257. PMID: 31776231; PMCID: PMC7306980.
    Citations: 51     Fields:    Translation:HumansCells
  9. Sugimura N, Otani K, Watanabe T, Nakatsu G, Shimada S, Fujimoto K, Nadatani Y, Hosomi S, Tanaka F, Kamata N, Taira K, Nagami Y, Tanigawa T, Uematsu S, Fujiwara Y. High-fat diet-mediated dysbiosis exacerbates NSAID-induced small intestinal damage through the induction of interleukin-17A. Sci Rep. 2019 11 14; 9(1):16796. PMID: 31727909.
    Citations: 8     Fields:    Translation:AnimalsCells
  10. Dong Y, Zhang Y, Kang W, Wang G, Chen H, Higashimori A, Nakatsu G, Go M, Tong JH, Zheng S, To KF, Sung JJ, Yang X, Ng SS, Yu J. VSTM2A suppresses colorectal cancer and antagonizes Wnt signaling receptor LRP6. Theranostics. 2019; 9(22):6517-6531. PMID: 31588233.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  11. Coker OO, Nakatsu G, Dai RZ, Wu WKK, Wong SH, Ng SC, Chan FKL, Sung JJY, Yu J. Enteric fungal microbiota dysbiosis and ecological alterations in colorectal cancer. Gut. 2019 04; 68(4):654-662. PMID: 30472682; PMCID: PMC6580778.
    Citations: 96     Fields:    Translation:Humans
  12. Wang X, Li X, Zhang L, Wong SH, Wang MHT, Tse G, Dai RZW, Nakatsu G, Coker OO, Chen Z, Ko H, Chan JYK, Liu T, Cheng CHK, Cheng ASL, To KF, Plewczynski D, Sung JJY, Yu J, Gin T, Chan MTV, Wu WKK. Oncogenes expand during evolution to withstand somatic amplification. Ann Oncol. 2018 11 01; 29(11):2254-2260. PMID: 30204835.
    Citations: 1     Fields:    Translation:HumansAnimals
  13. Li W, Wong CC, Zhang X, Kang W, Nakatsu G, Zhao Q, Chen H, Go MYY, Chiu PWY, Wang X, Ji J, Li X, Cai Z, Ng EKW, Yu J. CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1a axis to inhibit gastric tumorigenesis. Oncogene. 2018 12; 37(50):6383-6398. PMID: 30054562; PMCID: PMC6296350.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  14. Kwong TNY, Wang X, Nakatsu G, Chow TC, Tipoe T, Dai RZW, Tsoi KKK, Wong MCS, Tse G, Chan MTV, Chan FKL, Ng SC, Wu JCY, Wu WKK, Yu J, Sung JJY, Wong SH. Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer. Gastroenterology. 2018 08; 155(2):383-390.e8. PMID: 29729257.
    Citations: 68     Fields:    Translation:HumansCells
  15. Nakatsu G, Zhou H, Wu WKK, Wong SH, Coker OO, Dai Z, Li X, Szeto CH, Sugimura N, Lam TY, Yu AC, Wang X, Chen Z, Wong MC, Ng SC, Chan MTV, Chan PKS, Chan FKL, Sung JJ, Yu J. Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes. Gastroenterology. 2018 08; 155(2):529-541.e5. PMID: 29689266.
    Citations: 86     Fields:    Translation:HumansCells
  16. Dai Z, Coker OO, Nakatsu G, Wu WKK, Zhao L, Chen Z, Chan FKL, Kristiansen K, Sung JJY, Wong SH, Yu J. Multi-cohort analysis of colorectal cancer metagenome identified altered bacteria across populations and universal bacterial markers. Microbiome. 2018 04 11; 6(1):70. PMID: 29642940.
    Citations: 103     Fields:    Translation:HumansCells
  17. Cao L, Wang S, Zhang Y, Wong KC, Nakatsu G, Wang X, Wong S, Ji J, Yu J. Zinc-finger protein 471 suppresses gastric cancer through transcriptionally repressing downstream oncogenic PLS3 and TFAP2A. Oncogene. 2018 06; 37(26):3601-3616. PMID: 29610526; PMCID: PMC6021371.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  18. Higashimori A, Dong Y, Zhang Y, Kang W, Nakatsu G, Ng SSM, Arakawa T, Sung JJY, Chan FKL, Yu J. Forkhead Box F2 Suppresses Gastric Cancer through a Novel FOXF2-IRF2BPL-ß-Catenin Signaling Axis. Cancer Res. 2018 04 01; 78(7):1643-1656. PMID: 29374064.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  19. Wong SH, Zhao L, Zhang X, Nakatsu G, Han J, Xu W, Xiao X, Kwong TNY, Tsoi H, Wu WKK, Zeng B, Chan FKL, Sung JJY, Wei H, Yu J. Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice. Gastroenterology. 2017 12; 153(6):1621-1633.e6. PMID: 28823860.
    Citations: 164     Fields:    Translation:HumansAnimalsCells
  20. Coker OO, Dai Z, Nie Y, Zhao G, Cao L, Nakatsu G, Wu WK, Wong SH, Chen Z, Sung JJY, Yu J. Mucosal microbiome dysbiosis in gastric carcinogenesis. Gut. 2018 06; 67(6):1024-1032. PMID: 28765474; PMCID: PMC5969346.
    Citations: 173     Fields:    Translation:Humans
  21. Tsoi H, Chu ESH, Zhang X, Sheng J, Nakatsu G, Ng SC, Chan AWH, Chan FKL, Sung JJY, Yu J. Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice. Gastroenterology. 2017 05; 152(6):1419-1433.e5. PMID: 28126350.
    Citations: 109     Fields:    Translation:HumansAnimalsCells
  22. Xiao X, Nakatsu G, Jin Y, Wong S, Yu J, Lau JY. Gut Microbiota Mediates Protection Against Enteropathy Induced by Indomethacin. Sci Rep. 2017 01 09; 7:40317. PMID: 28067296.
    Citations: 17     Fields:    Translation:Animals
  23. Wong SH, Kwong TNY, Chow TC, Luk AKC, Dai RZW, Nakatsu G, Lam TYT, Zhang L, Wu JCY, Chan FKL, Ng SSM, Wong MCS, Ng SC, Wu WKK, Yu J, Sung JJY. Quantitation of faecal Fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia. Gut. 2017 08; 66(8):1441-1448. PMID: 27797940; PMCID: PMC5530471.
    Citations: 82     Fields:    Translation:HumansCells
  24. Wu R, Nakatsu G, Zhang X, Yu J. Pathophysiological mechanisms and therapeutic potentials of macrophages in non-alcoholic steatohepatitis. Expert Opin Ther Targets. 2016; 20(5):615-26. PMID: 26609894.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  25. Nakatsu G, Li X, Zhou H, Sheng J, Wong SH, Wu WK, Ng SC, Tsoi H, Dong Y, Zhang N, He Y, Kang Q, Cao L, Wang K, Zhang J, Liang Q, Yu J, Sung JJ. Gut mucosal microbiome across stages of colorectal carcinogenesis. Nat Commun. 2015 Oct 30; 6:8727. PMID: 26515465.
    Citations: 228     Fields:    Translation:HumansCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: SPH faculty should contact Faculty Affairs at facultyaffairshsph.harvard.edu).
Nakatsu's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (155)
Co-Authors (4)
Similar People (60)
Same Department 
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.