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Rajat Gupta, M.D.

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Biography
University of PennsylvaniaM.D.04/2007Medicine
Massachusetts General Hospital06/2010Internal Medicine
Brigham and Women's Hospital07/2014Cardiovascular Medicine
Broad Institute07/2018Human Genetics

Overview
Rajat Gupta, MD is an Assistant Professor of Medicine at Harvard Medical School with a research laboratory in the Divisions of Cardiovascular Medicine and Genetics at Brigham and Women’s Hospital. His research is focused on identifying new treatments for vascular disease using human genetics to discover novel biologic pathways. His post-doctoral work identified non-coding variants in the 6p24 locus as distal regulators of Endothelin-1 (Cell, 2017). Dr. Gupta’s laboratory recently identified the transcriptional signature of distinct endothelial cell populations using single cell RNA-sequencing (Circulation, 2019).

Dr. Gupta graduated from the University of Pennsylvania School of Medicine (2007) where he was awarded the Adolf J. Creskoff Prize. He completed Internal Medicine residency training at Massachusetts General Hospital (2010), cardiology fellowship at Brigham and Women’s Hospital (2014), and a post-doctoral fellowship in Human Genetics at the Broad Institute of Harvard and MIT (2016). Dr. Gupta has been named the Thomas W. Smith Fellow at Brigham and Women’s Hospital and received the Lerner Junior Faculty Award. His research is funded by grants from the NIH (New Innovator Award), the Broad Institute, the Sperling Family Fellowship, and the Chan Zuckerberg Initiative.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL164811 (GUPTA, RAJAT M) Apr 1, 2023 - Mar 31, 2027
    NIH
    High-throughput cellular genetics to connect noncoding variants to coronary artery disease genes
    Role: Principal Investigator
  2. R01HL164811 (GUPTA, RAJAT M) Apr 1, 2023 - Mar 30, 2027
    NIH/NHLBI
    High-throughput cellular genetics to connect noncoding variants to coronary artery disease genes
    Role: Principal Investigator
  3. U01HL166060 (GUPTA, RAJAT M) Jul 1, 2022 - Jun 30, 2026
    NIH
    Identifying the organotypic and disease-specific vascular cell populations by integrating single cell data with polygenic risk
    Role: Principal Investigator
  4. U01HL166060 (GUPTA, RAJAT M) Jul 1, 2022 - Jun 30, 2026
    NIH/NHLBI
    Identifying the organotypic and disease-specific vascular cell populations by integrating single cell data with polygenic risk
    Role: Principal Investigator
  5. DP2HL152423 (GUPTA, RAJAT M) Sep 1, 2019 - Apr 30, 2024
    NIH
    A genetic approach to identify the common mechanisms of vascular disease
    Role: Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.