Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Jason Daniel Buenrostro, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. UM1HG011986 (BUENROSTRO, JASON DANIEL) Sep 9, 2021 - May 31, 2026
    A Foundational Resource of Functional Elements, TF footprints and Gene Regulatory Interactions
    Role: Principal Investigator
  2. U01MH124602 (MACOSKO, EVAN Z) Dec 5, 2020 - Oct 31, 2023
    A cellular atlas of the primate and human basal ganglia
    Role: Co-Principal Investigator
  3. DP2HL151353 (BUENROSTRO, JASON DANIEL) Sep 15, 2019 - Apr 30, 2024
    Single-cell epigenomic and cellular plasticity
    Role: Principal Investigator
  4. R21HG009749 (BUENROSTRO, JASON DANIEL) Aug 18, 2017 - May 31, 2019
    In situ ATAC-seq, a novel technology for structural epigenomics
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Uzquiano A, Kedaigle AJ, Pigoni M, Paulsen B, Adiconis X, Kim K, Faits T, Nagaraja S, Antón-Bolaños N, Gerhardinger C, Tucewicz A, Murray E, Jin X, Buenrostro J, Chen F, Velasco S, Regev A, Levin JZ, Arlotta P. Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex. Cell. 2022 Sep 29; 185(20):3770-3788.e27. PMID: 36179669.
    Citations:    Fields:    Translation:HumansCells
  2. Kartha VK, Duarte FM, Hu Y, Ma S, Chew JG, Lareau CA, Earl A, Burkett ZD, Kohlway AS, Lebofsky R, Buenrostro JD. Functional inference of gene regulation using single-cell multi-omics. Cell Genom. 2022 Sep 14; 2(9). PMID: 36204155; PMCID: PMC9534481.
    Citations: 1     
  3. Yuan W, Ma S, Brown JR, Kim K, Murek V, Trastulla L, Meissner A, Lodato S, Shetty AS, Levin JZ, Buenrostro JD, Ziller MJ, Arlotta P. Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex. Nat Neurosci. 2022 08; 25(8):1049-1058. PMID: 35915179; PMCID: PMC9343253.
    Citations:    Fields:    Translation:AnimalsCells
  4. Zhao T, Chiang ZD, Morriss JW, LaFave LM, Murray EM, Del Priore I, Meli K, Lareau CA, Nadaf NM, Li J, Earl AS, Macosko EZ, Jacks T, Buenrostro JD, Chen F. Spatial genomics enables multi-modal study of clonal heterogeneity in tissues. Nature. 2022 01; 601(7891):85-91. PMID: 34912115; PMCID: PMC9301586.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  5. Biancalani T, Scalia G, Buffoni L, Avasthi R, Lu Z, Sanger A, Tokcan N, Vanderburg CR, Segerstolpe Å, Zhang M, Avraham-Davidi I, Vickovic S, Nitzan M, Ma S, Subramanian A, Lipinski M, Buenrostro J, Brown NB, Fanelli D, Zhuang X, Macosko EZ, Regev A. Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram. Nat Methods. 2021 11; 18(11):1352-1362. PMID: 34711971.
    Citations: 12     Fields:    Translation:AnimalsCells
  6. Concepcion CP, Ma S, LaFave LM, Bhutkar A, Liu M, DeAngelo LP, Kim JY, Del Priore I, Schoenfeld AJ, Miller M, Kartha VK, Westcott PMK, Sánchez-Rivera FJ, Meli K, Gupta M, Bronson RT, Riely GJ, Rekhtman N, Rudin CM, Kim CF, Regev A, Buenrostro JD, Jacks T. Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung. Cancer Discov. 2022 02; 12(2):562-585. PMID: 34561242; PMCID: PMC8831463.
    Citations: 2     Fields:    Translation:HumansAnimals
  7. Avagyan S, Weber MC, Ma S, Prasad M, Mannherz WP, Yang S, Buenrostro JD, Zon LI. Single-cell ATAC-seq reveals GATA2-dependent priming defect in myeloid and a maturation bottleneck in lymphoid lineages. Blood Adv. 2021 07 13; 5(13):2673-2686. PMID: 34170284; PMCID: PMC8221101.
    Citations: 3     Fields:    Translation:Animals
  8. Rose SA, Wroblewska A, Dhainaut M, Yoshida H, Shaffer JM, Bektesevic A, Ben-Zvi B, Rhoads A, Kim EY, Yu B, Lavin Y, Merad M, Buenrostro JD, Brown BD. A microRNA expression and regulatory element activity atlas of the mouse immune system. Nat Immunol. 2021 07; 22(7):914-927. PMID: 34099919; PMCID: PMC8480231.
    Citations: 5     Fields:    Translation:AnimalsCells
  9. Del Priore I, Ma S, Strecker J, Jacks T, LaFave LM, Buenrostro JD. Protocol for single-cell ATAC sequencing using combinatorial indexing in mouse lung adenocarcinoma. STAR Protoc. 2021 06 18; 2(2):100583. PMID: 34142101; PMCID: PMC8185305.
    Citations: 1     Fields:    Translation:Animals
  10. Choi S, Zhang B, Ma S, Gonzalez-Celeiro M, Stein D, Jin X, Kim ST, Kang YL, Besnard A, Rezza A, Grisanti L, Buenrostro JD, Rendl M, Nahrendorf M, Sahay A, Hsu YC. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence. Nature. 2021 04; 592(7854):428-432. PMID: 33790465; PMCID: PMC8923613.
    Citations: 10     Fields:    Translation:AnimalsCells
  11. Lal A, Chiang ZD, Yakovenko N, Duarte FM, Israeli J, Buenrostro JD. Deep learning-based enhancement of epigenomics data with AtacWorks. Nat Commun. 2021 03 08; 12(1):1507. PMID: 33686069.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  12. Li Q, Meissner TB, Wang F, Du Z, Ma S, Kshirsagar S, Tilburgs T, Buenrostro JD, Uesugi M, Strominger JL. ELF3 activated by a superenhancer and an autoregulatory feedback loop is required for high-level HLA-C expression on extravillous trophoblasts. Proc Natl Acad Sci U S A. 2021 03 02; 118(9). PMID: 33622787.
    Citations: 2     Fields:    Translation:HumansCells
  13. LaFave LM, Buenrostro JD. Unlocking PDAC initiation with AP-1. Nat Cancer. 2021 01; 2(1):14-15. PMID: 35121892.
    Citations:    Translation:Humans
  14. Payne AC, Chiang ZD, Reginato PL, Mangiameli SM, Murray EM, Yao CC, Markoulaki S, Earl AS, Labade AS, Jaenisch R, Church GM, Boyden ES, Buenrostro JD, Chen F. In situ genome sequencing resolves DNA sequence and structure in intact biological samples. Science. 2021 02 26; 371(6532). PMID: 33384301.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  15. Ma S, Zhang B, LaFave LM, Earl AS, Chiang Z, Hu Y, Ding J, Brack A, Kartha VK, Tay T, Law T, Lareau C, Hsu YC, Regev A, Buenrostro JD. Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin. Cell. 2020 11 12; 183(4):1103-1116.e20. PMID: 33098772.
    Citations: 111     Fields:    Translation:AnimalsCells
  16. Lareau CA, Ludwig LS, Muus C, Gohil SH, Zhao T, Chiang Z, Pelka K, Verboon JM, Luo W, Christian E, Rosebrock D, Getz G, Boland GM, Chen F, Buenrostro JD, Hacohen N, Wu CJ, Aryee MJ, Regev A, Sankaran VG. Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling. Nat Biotechnol. 2021 04; 39(4):451-461. PMID: 32788668.
    Citations: 38     Fields:    Translation:HumansCells
  17. Agbleke AA, Amitai A, Buenrostro JD, Chakrabarti A, Chu L, Hansen AS, Koenig KM, Labade AS, Liu S, Nozaki T, Ovchinnikov S, Seeber A, Shaban HA, Spille JH, Stephens AD, Su JH, Wadduwage D. Advances in Chromatin and Chromosome Research: Perspectives from Multiple Fields. Mol Cell. 2020 09 17; 79(6):881-901. PMID: 32768408.
    Citations: 11     Fields:    Translation:HumansCells
  18. LaFave LM, Kartha VK, Ma S, Meli K, Del Priore I, Lareau C, Naranjo S, Westcott PMK, Duarte FM, Sankar V, Chiang Z, Brack A, Law T, Hauck H, Okimoto A, Regev A, Buenrostro JD, Jacks T. Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma. Cancer Cell. 2020 08 10; 38(2):212-228.e13. PMID: 32707078.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  19. Sarikhani M, Garbern JC, Ma S, Sereda R, Conde J, Krähenbühl G, Escalante GO, Ahmed A, Buenrostro JD, Lee RT. Sustained Activation of AMPK Enhances Differentiation of Human iPSC-Derived Cardiomyocytes via Sirtuin Activation. Stem Cell Reports. 2020 08 11; 15(2):498-514. PMID: 32649901.
    Citations: 5     Fields:    Translation:HumansCells
  20. Lareau CA, Ma S, Duarte FM, Buenrostro JD. Inference and effects of barcode multiplets in droplet-based single-cell assays. Nat Commun. 2020 02 13; 11(1):866. PMID: 32054859.
    Citations: 8     Fields:    Translation:HumansCells
  21. Zhang B, Ma S, Rachmin I, He M, Baral P, Choi S, Gonçalves WA, Shwartz Y, Fast EM, Su Y, Zon LI, Regev A, Buenrostro JD, Cunha TM, Chiu IM, Fisher DE, Hsu YC. Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells. Nature. 2020 01; 577(7792):676-681. PMID: 31969699; PMCID: PMC7184936.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  22. Chen H, Lareau C, Andreani T, Vinyard ME, Garcia SP, Clement K, Andrade-Navarro MA, Buenrostro JD, Pinello L. Assessment of computational methods for the analysis of single-cell ATAC-seq data. Genome Biol. 2019 11 18; 20(1):241. PMID: 31739806; PMCID: PMC6859644.
    Citations: 74     Fields:    Translation:HumansAnimals
  23. Lareau CA, Duarte FM, Chew JG, Kartha VK, Burkett ZD, Kohlway AS, Pokholok D, Aryee MJ, Steemers FJ, Lebofsky R, Buenrostro JD. Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility. Nat Biotechnol. 2019 08; 37(8):916-924. PMID: 31235917.
    Citations: 85     Fields:    Translation:HumansAnimalsCells
  24. Ludwig LS, Lareau CA, Bao EL, Nandakumar SK, Muus C, Ulirsch JC, Chowdhary K, Buenrostro JD, Mohandas N, An X, Aryee MJ, Regev A, Sankaran VG. Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis. Cell Rep. 2019 06 11; 27(11):3228-3240.e7. PMID: 31189107.
    Citations: 50     Fields:    Translation:HumansCells
  25. Chen H, Albergante L, Hsu JY, Lareau CA, Lo Bosco G, Guan J, Zhou S, Gorban AN, Bauer DE, Aryee MJ, Langenau DM, Zinovyev A, Buenrostro JD, Yuan GC, Pinello L. Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM. Nat Commun. 2019 04 23; 10(1):1903. PMID: 31015418.
    Citations: 61     Fields:    Translation:AnimalsCells
  26. Ulirsch JC, Lareau CA, Bao EL, Ludwig LS, Guo MH, Benner C, Satpathy AT, Kartha VK, Salem RM, Hirschhorn JN, Finucane HK, Aryee MJ, Buenrostro JD, Sankaran VG. Interrogation of human hematopoiesis at single-cell and single-variant resolution. Nat Genet. 2019 04; 51(4):683-693. PMID: 30858613.
    Citations: 59     Fields:    Translation:HumansCells
  27. Ludwig LS, Lareau CA, Ulirsch JC, Christian E, Muus C, Li LH, Pelka K, Ge W, Oren Y, Brack A, Law T, Rodman C, Chen JH, Boland GM, Hacohen N, Rozenblatt-Rosen O, Aryee MJ, Buenrostro JD, Regev A, Sankaran VG. Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics. Cell. 2019 03 07; 176(6):1325-1339.e22. PMID: 30827679; PMCID: PMC6408267.
    Citations: 114     Fields:    Translation:HumansCells
  28. Yoshida H, Lareau CA, Ramirez RN, Rose SA, Maier B, Wroblewska A, Desland F, Chudnovskiy A, Mortha A, Dominguez C, Tellier J, Kim E, Dwyer D, Shinton S, Nabekura T, Qi Y, Yu B, Robinette M, Kim KW, Wagers A, Rhoads A, Nutt SL, Brown BD, Mostafavi S, Buenrostro JD, Benoist C. The cis-Regulatory Atlas of the Mouse Immune System. Cell. 2019 02 07; 176(4):897-912.e20. PMID: 30686579.
    Citations: 110     Fields:    Translation:AnimalsCells
  29. Shema E, Bernstein BE, Buenrostro JD. Single-cell and single-molecule epigenomics to uncover genome regulation at unprecedented resolution. Nat Genet. 2019 01; 51(1):19-25. PMID: 30559489.
    Citations: 57     Fields:    Translation:HumansAnimalsCells
  30. Zviran A, Mor N, Rais Y, Gingold H, Peles S, Chomsky E, Viukov S, Buenrostro JD, Scognamiglio R, Weinberger L, Manor YS, Krupalnik V, Zerbib M, Hezroni H, Jaitin DA, Larastiaso D, Gilad S, Benjamin S, Gafni O, Mousa A, Ayyash M, Sheban D, Bayerl J, Aguilera-Castrejon A, Massarwa R, Maza I, Hanna S, Stelzer Y, Ulitsky I, Greenleaf WJ, Tanay A, Trumpp A, Amit I, Pilpel Y, Novershtern N, Hanna JH. Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules. Cell Stem Cell. 2019 02 07; 24(2):328-341.e9. PMID: 30554962; PMCID: PMC7116520.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  31. Mor N, Rais Y, Sheban D, Peles S, Aguilera-Castrejon A, Zviran A, Elinger D, Viukov S, Geula S, Krupalnik V, Zerbib M, Chomsky E, Lasman L, Shani T, Bayerl J, Gafni O, Hanna S, Buenrostro JD, Hagai T, Masika H, Vainorius G, Bergman Y, Greenleaf WJ, Esteban MA, Elling U, Levin Y, Massarwa R, Merbl Y, Novershtern N, Hanna JH. Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency. Cell Stem Cell. 2018 09 06; 23(3):412-425.e10. PMID: 30122475.
    Citations: 20     Fields:    Translation:AnimalsCells
  32. Chihara N, Madi A, Kondo T, Zhang H, Acharya N, Singer M, Nyman J, Marjanovic ND, Kowalczyk MS, Wang C, Kurtulus S, Law T, Etminan Y, Nevin J, Buckley CD, Burkett PR, Buenrostro JD, Rozenblatt-Rosen O, Anderson AC, Regev A, Kuchroo VK. Induction and transcriptional regulation of the co-inhibitory gene module in T cells. Nature. 2018 06; 558(7710):454-459. PMID: 29899446.
    Citations: 138     Fields:    Translation:AnimalsCells
  33. Buenrostro JD, Corces MR, Lareau CA, Wu B, Schep AN, Aryee MJ, Majeti R, Chang HY, Greenleaf WJ. Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation. Cell. 2018 05 31; 173(6):1535-1548.e16. PMID: 29706549.
    Citations: 176     Fields:    Translation:HumansAnimalsCells
  34. Satpathy AT, Saligrama N, Buenrostro JD, Wei Y, Wu B, Rubin AJ, Granja JM, Lareau CA, Li R, Qi Y, Parker KR, Mumbach MR, Serratelli WS, Gennert DG, Schep AN, Corces MR, Khodadoust MS, Kim YH, Khavari PA, Greenleaf WJ, Davis MM, Chang HY. Transcript-indexed ATAC-seq for precision immune profiling. Nat Med. 2018 05; 24(5):580-590. PMID: 29686426.
    Citations: 53     Fields:    Translation:HumansCells
  35. Finucane HK, Reshef YA, Anttila V, Slowikowski K, Gusev A, Byrnes A, Gazal S, Loh PR, Lareau C, Shoresh N, Genovese G, Saunders A, Macosko E, Pollack S, Perry JRB, Buenrostro JD, Bernstein BE, Raychaudhuri S, McCarroll S, Neale BM, Price AL. Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. Nat Genet. 2018 04; 50(4):621-629. PMID: 29632380.
    Citations: 281     Fields:    Translation:HumansCells
  36. Koh AS, Miller EL, Buenrostro JD, Moskowitz DM, Wang J, Greenleaf WJ, Chang HY, Crabtree GR. Rapid chromatin repression by Aire provides precise control of immune tolerance. Nat Immunol. 2018 02; 19(2):162-172. PMID: 29335648; PMCID: PMC6049828.
    Citations: 15     Fields:    Translation:AnimalsCells
  37. Daugherty AC, Yeo RW, Buenrostro JD, Greenleaf WJ, Kundaje A, Brunet A. Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans. Genome Res. 2017 12; 27(12):2096-2107. PMID: 29141961; PMCID: PMC5741055.
    Citations: 59     Fields:    Translation:AnimalsCells
  38. Schep AN, Wu B, Buenrostro JD, Greenleaf WJ. chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data. Nat Methods. 2017 Oct; 14(10):975-978. PMID: 28825706; PMCID: PMC5623146.
    Citations: 280     Fields:    Translation:AnimalsCells
  39. Soto-Feliciano YM, Bartlebaugh JME, Liu Y, Sánchez-Rivera FJ, Bhutkar A, Weintraub AS, Buenrostro JD, Cheng CS, Regev A, Jacks TE, Young RA, Hemann MT. PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes. Genes Dev. 2017 05 15; 31(10):973-989. PMID: 28607179; PMCID: PMC5495126.
    Citations: 15     Fields:    Translation:AnimalsCells
  40. She R, Chakravarty AK, Layton CJ, Chircus LM, Andreasson JO, Damaraju N, McMahon PL, Buenrostro JD, Jarosz DF, Greenleaf WJ. Comprehensive and quantitative mapping of RNA-protein interactions across a transcribed eukaryotic genome. Proc Natl Acad Sci U S A. 2017 04 04; 114(14):3619-3624. PMID: 28325876; PMCID: PMC5389288.
    Citations: 24     Fields:    Translation:AnimalsCells
  41. Miller EL, Hargreaves DC, Kadoch C, Chang CY, Calarco JP, Hodges C, Buenrostro JD, Cui K, Greenleaf WJ, Zhao K, Crabtree GR. TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin. Nat Struct Mol Biol. 2017 04; 24(4):344-352. PMID: 28250416; PMCID: PMC5395302.
    Citations: 36     Fields:    Translation:AnimalsCells
  42. Moskowitz DM, Zhang DW, Hu B, Le Saux S, Yanes RE, Ye Z, Buenrostro JD, Weyand CM, Greenleaf WJ, Goronzy JJ. Epigenomics of human CD8 T cell differentiation and aging. Sci Immunol. 2017 Feb; 2(8). PMID: 28439570.
    Citations: 87     Fields:    
  43. Litzenburger UM, Buenrostro JD, Wu B, Shen Y, Sheffield NC, Kathiria A, Greenleaf WJ, Chang HY. Single-cell epigenomic variability reveals functional cancer heterogeneity. Genome Biol. 2017 01 24; 18(1):15. PMID: 28118844; PMCID: PMC5259890.
    Citations: 36     Fields:    Translation:HumansCells
  44. Guo MH, Nandakumar SK, Ulirsch JC, Zekavat SM, Buenrostro JD, Natarajan P, Salem RM, Chiarle R, Mitt M, Kals M, Pärn K, Fischer K, Milani L, Mägi R, Palta P, Gabriel SB, Metspalu A, Lander ES, Kathiresan S, Hirschhorn JN, Esko T, Sankaran VG. Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Proc Natl Acad Sci U S A. 2017 01 17; 114(3):E327-E336. PMID: 28031487; PMCID: PMC5255587.
    Citations: 22     Fields:    Translation:HumansCells
  45. Chen X, Shen Y, Draper W, Buenrostro JD, Litzenburger U, Cho SW, Satpathy AT, Carter AC, Ghosh RP, East-Seletsky A, Doudna JA, Greenleaf WJ, Liphardt JT, Chang HY. ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing. Nat Methods. 2016 Dec; 13(12):1013-1020. PMID: 27749837; PMCID: PMC5509561.
    Citations: 78     Fields:    Translation:HumansCells
  46. Corces MR, Buenrostro JD, Wu B, Greenside PG, Chan SM, Koenig JL, Snyder MP, Pritchard JK, Kundaje A, Greenleaf WJ, Majeti R, Chang HY. Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution. Nat Genet. 2016 10; 48(10):1193-203. PMID: 27526324; PMCID: PMC5042844.
    Citations: 395     Fields:    Translation:HumansCells
  47. Mazumdar C, Shen Y, Xavy S, Zhao F, Reinisch A, Li R, Corces MR, Flynn RA, Buenrostro JD, Chan SM, Thomas D, Koenig JL, Hong WJ, Chang HY, Majeti R. Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation. Cell Stem Cell. 2015 Dec 03; 17(6):675-688. PMID: 26607380.
    Citations: 98     Fields:    Translation:HumansCells
  48. Schep AN, Buenrostro JD, Denny SK, Schwartz K, Sherlock G, Greenleaf WJ. Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions. Genome Res. 2015 Nov; 25(11):1757-70. PMID: 26314830; PMCID: PMC4617971.
    Citations: 141     Fields:    Translation:HumansAnimalsCells
  49. Maza I, Caspi I, Zviran A, Chomsky E, Rais Y, Viukov S, Geula S, Buenrostro JD, Weinberger L, Krupalnik V, Hanna S, Zerbib M, Dutton JR, Greenleaf WJ, Massarwa R, Novershtern N, Hanna JH. Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors. Nat Biotechnol. 2015 Jul; 33(7):769-74. PMID: 26098448; PMCID: PMC4500825.
    Citations: 66     Fields:    Translation:AnimalsCells
  50. Buenrostro JD, Wu B, Litzenburger UM, Ruff D, Gonzales ML, Snyder MP, Chang HY, Greenleaf WJ. Single-cell chromatin accessibility reveals principles of regulatory variation. Nature. 2015 Jul 23; 523(7561):486-90. PMID: 26083756.
    Citations: 686     Fields:    Translation:HumansAnimalsCells
  51. Buenrostro JD, Wu B, Chang HY, Greenleaf WJ. ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide. Curr Protoc Mol Biol. 2015 Jan 05; 109:21.29.1-21.29.9. PMID: 25559105; PMCID: PMC4374986.
    Citations: 897     Fields:    Translation:Cells
  52. Buenrostro JD, Araya CL, Chircus LM, Layton CJ, Chang HY, Snyder MP, Greenleaf WJ. Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes. Nat Biotechnol. 2014 Jun; 32(6):562-8. PMID: 24727714.
    Citations: 105     Fields:    Translation:HumansAnimalsCells
  53. Couthouis J, Raphael AR, Siskind C, Findlay AR, Buenrostro JD, Greenleaf WJ, Vogel H, Day JW, Flanigan KM, Gitler AD. Exome sequencing identifies a DNAJB6 mutation in a family with dominantly-inherited limb-girdle muscular dystrophy. Neuromuscul Disord. 2014 May; 24(5):431-5. PMID: 24594375; PMCID: PMC4013999.
    Citations: 21     Fields:    Translation:Humans
  54. Carpenter ML, Buenrostro JD, Valdiosera C, Schroeder H, Allentoft ME, Sikora M, Rasmussen M, Gravel S, Guillén S, Nekhrizov G, Leshtakov K, Dimitrova D, Theodossiev N, Pettener D, Luiselli D, Sandoval K, Moreno-Estrada A, Li Y, Wang J, Gilbert MT, Willerslev E, Greenleaf WJ, Bustamante CD. Pulling out the 1%: whole-genome capture for the targeted enrichment of ancient DNA sequencing libraries. Am J Hum Genet. 2013 Nov 07; 93(5):852-64. PMID: 24568772.
    Citations: 87     Fields:    Translation:HumansCells
  55. Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nat Methods. 2013 Dec; 10(12):1213-8. PMID: 24097267.
    Citations: 2296     Fields:    Translation:HumansCells
  56. Myllykangas S, Buenrostro JD, Natsoulis G, Bell JM, Ji HP. Efficient targeted resequencing of human germline and cancer genomes by oligonucleotide-selective sequencing. Nat Biotechnol. 2011 Oct 23; 29(11):1024-7. PMID: 22020387.
    Citations: 31     Fields:    Translation:HumansCells
  57. Flaherty P, Natsoulis G, Muralidharan O, Winters M, Buenrostro J, Bell J, Brown S, Holodniy M, Zhang N, Ji HP. Ultrasensitive detection of rare mutations using next-generation targeted resequencing. Nucleic Acids Res. 2012 Jan; 40(1):e2. PMID: 22013163.
    Citations: 79     Fields:    Translation:HumansCells
  58. Natsoulis G, Bell JM, Xu H, Buenrostro JD, Ordonez H, Grimes S, Newburger D, Jensen M, Zahn JM, Zhang N, Ji HP. A flexible approach for highly multiplexed candidate gene targeted resequencing. PLoS One. 2011; 6(6):e21088. PMID: 21738606.
    Citations: 13     Fields:    Translation:Humans
  59. Dick CA, Buenrostro J, Butler T, Carlson ML, Kliebenstein DJ, Whittall JB. Arctic mustard flower color polymorphism controlled by petal-specific downregulation at the threshold of the anthocyanin biosynthetic pathway. PLoS One. 2011 Apr 07; 6(4):e18230. PMID: 21490971.
    Citations: 29     Fields:    Translation:AnimalsCells
  60. Whittall JB, Syring J, Parks M, Buenrostro J, Dick C, Liston A, Cronn R. Finding a (pine) needle in a haystack: chloroplast genome sequence divergence in rare and widespread pines. Mol Ecol. 2010 Mar; 19 Suppl 1:100-14. PMID: 20331774.
    Citations: 36     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.