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Marouen Ben Guebila, Ph.D., B.M., M.B.

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My research is at the interface of genomics, machine learning, and network biology. I often combine tools from these disciplines to address fundamental questions about the functioning of biological systems. I develop open-source, parallel software to leverage high-dimensional biological data to model regulatory genomics, small molecule dynamics, and metabolism in time and space.
I am currently a postdoctoral fellow at the Quackenbush lab at the Biostatistics department.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ben Guebila M, Lopes-Ramos CM, Weighill D, Sonawane AR, Burkholz R, Shamsaei B, Platig J, Glass K, Kuijjer ML, Quackenbush J. GRAND: a database of gene regulatory network models across human conditions. Nucleic Acids Res. 2021 Sep 11. PMID: 34508353.
    Citations:    Fields:    
  2. Lopes-Ramos CM, Belova T, Brunner TH, Ben Guebila M, Osorio D, Quackenbush J, Kuijjer ML. Regulatory network of PD1 signaling is associated with prognosis in glioblastoma multiforme. Cancer Res. 2021 Sep 07. PMID: 34493595.
    Citations:    Fields:    
  3. Weighill D, Ben Guebila M, Glass K, Platig J, Yeh JJ, Quackenbush J. Gene Targeting in Disease Networks. Front Genet. 2021; 12:649942. PMID: 33968133.
  4. Guebila MB. VFFVA: dynamic load balancing enables large-scale flux variability analysis. BMC Bioinformatics. 2020 Sep 29; 21(1):424. PMID: 32993482.
    Citations:    Fields:    Translation:HumansCells
  5. Ben Guebila M, Thiele I. Predicting gastrointestinal drug effects using contextualized metabolic models. PLoS Comput Biol. 2019 06; 15(6):e1007100. PMID: 31242176.
    Citations: 2     Fields:    Translation:Humans
  6. Heirendt L, Arreckx S, Pfau T, Mendoza SN, Richelle A, Heinken A, Haraldsdóttir HS, Wachowiak J, Keating SM, Vlasov V, Magnusdóttir S, Ng CY, Preciat G, Žagare A, Chan SHJ, Aurich MK, Clancy CM, Modamio J, Sauls JT, Noronha A, Bordbar A, Cousins B, El Assal DC, Valcarcel LV, Apaolaza I, Ghaderi S, Ahookhosh M, Ben Guebila M, Kostromins A, Sompairac N, Le HM, Ma D, Sun Y, Wang L, Yurkovich JT, Oliveira MAP, Vuong PT, El Assal LP, Kuperstein I, Zinovyev A, Hinton HS, Bryant WA, Aragón Artacho FJ, Planes FJ, Stalidzans E, Maass A, Vempala S, Hucka M, Saunders MA, Maranas CD, Lewis NE, Sauter T, Palsson BØ, Thiele I, Fleming RMT. Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0. Nat Protoc. 2019 03; 14(3):639-702. PMID: 30787451.
    Citations: 133     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.