Harvard Catalyst Profiles

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Andre Felipe Batista, Ph.D.

Title
Institution
Department
Address

Biography
education and training
Federal University of Rio de Janeiro, Biophysic Institute Carlos Chagas FilhoB.Sc.03/2011Biophysics
Federal University of Rio de Janeiro, Institute of Medical Biochemistry Leopoldo de MeisMsc08/2013Biomedical Chemistry
Federal University of Rio de Janeiro, Institute of Medical Biochemistry Leopoldo de MeisPhD08/2017Biomedical Chemistry

Overview
overview
Graduation in Biophysics by Federal University of Rio de Janeiro (UFRJ), Brazil in 2010. Msc in Biomedical Chemistry (2013) and PhD in 2017 by UFRJ. In addition, Postdoc Researcher at UFRJ for 18 months (2017-2019). Currently, I am a Research Fellow at Brigham and Women's Hospital and Harvard Medical School. I have an experience in neurobiology celular and biochemistry, with emphasis in immune system, neuroinflammation, mitochondrial dysfunction in Alzheimer's Disease. Further, I had been working in the neuroprotective effects of Liraglutide, an antidiabetic agent, in Alzheimer's Disease models. Now, during my stay at Harvard Medical School, I am investigating the role of complement system and synaptic plasticity in Alzheimer's Disease models.
keywords

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Batista AF, Schroeder MK, Khan K, Li SA, Presumey J, Yalcin E, Carroll M, Lemere CA. Global C3 lowering alleviates hippocampal dysfunction and cognitive impairment in aged mice. Alzheimers Dement. 2021 Dec; 17 Suppl 2:e058736. PMID: 34971204.
    Citations:    Fields:    
  2. Batista AF, Bodart-Santos V, De Felice FG, Ferreira ST. Neuroprotective Actions of Glucagon-Like Peptide-1 (GLP-1) Analogues in Alzheimer's and Parkinson's Diseases. CNS Drugs. 2019 03; 33(3):209-223. PMID: 30511349.
    Citations: 19     Fields:    Translation:HumansAnimals
  3. Batista AF, Forny-Germano L, Clarke JR, Lyra E Silva NM, Brito-Moreira J, Boehnke SE, Winterborn A, Coe BC, Lablans A, Vital JF, Marques SA, Martinez AM, Gralle M, Holscher C, Klein WL, Houzel JC, Ferreira ST, Munoz DP, De Felice FG. The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease. J Pathol. 2018 05; 245(1):85-100. PMID: 29435980; PMCID: PMC5947670.
    Citations: 87     Fields:    Translation:AnimalsCells
  4. De Felice, F. G.; Batista, A. F.; Forny-Germano, L.; Lyra e Silva, N. M.; BritoMoreira, J.; Gralle, M.; Boehnke, S. E.; Coe, B. C.; Lablans, A.; Holscher, C; Klein, W. L.; Houzel, J. C.; Martinez, A. M. B.; Marques, S. A.; Ferreira, S. T.; Munoz, D. P. Liraglutide protects the brains of macaques against synapse loss caused by abeta oligomers. 2015; 11( 7):P905–P906.
  5. Forny-Germano L, Lyra e Silva NM, Batista AF, Brito-Moreira J, Gralle M, Boehnke SE, Coe BC, Lablans A, Marques SA, Martinez AM, Klein WL, Houzel JC, Ferreira ST, Munoz DP, De Felice FG. Alzheimer's disease-like pathology induced by amyloid-ß oligomers in nonhuman primates. J Neurosci. 2014 Oct 08; 34(41):13629-43. PMID: 25297091.
    Citations: 101     Fields:    Translation:AnimalsCells
  6. Macedo-Ramos H, Batista AF, Carrier-Ruiz A, Alves L, Allodi S, Ribeiro-Resende VT, Teixeira LM, Baetas-da-Cruz W. Evidence of involvement of the mannose receptor in the internalization of Streptococcus pneumoniae by Schwann cells. BMC Microbiol. 2014 Aug 02; 14:211. PMID: 25085553; PMCID: PMC4236529.
    Citations: 10     Fields:    Translation:AnimalsCells
  7. Lourenco MV, Clarke JR, Frozza RL, Bomfim TR, Forny-Germano L, Batista AF, Sathler LB, Brito-Moreira J, Amaral OB, Silva CA, Freitas-Correa L, Espírito-Santo S, Campello-Costa P, Houzel JC, Klein WL, Holscher C, Carvalheira JB, Silva AM, Velloso LA, Munoz DP, Ferreira ST, De Felice FG. TNF-a mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's ß-amyloid oligomers in mice and monkeys. Cell Metab. 2013 Dec 03; 18(6):831-43. PMID: 24315369.
    Citations: 170     Fields:    Translation:AnimalsCells
  8. Forny-Germano, L.; Lyra e Silva, N. M.; Brito-Moreira,J.; Batista, A. F.; Martins, S.; Klein, W. L.; Houzel, J. C.; Ferreira, S. T.; Munoz, D. P.; De Felice,F. G. A nonhuman primate model of Alzheimer's disease with tangles and synapse loss triggered by Aß oligomers. 2012; 8(4): P203 .
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