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Jana Grune, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Grune J, Yamazoe M, Nahrendorf M. Electroimmunology and cardiac arrhythmia. Nat Rev Cardiol. 2021 Mar 02. PMID: 33654273.
    Citations:    Fields:    
  2. Hannemann C, Schecker JH, Brettschneider A, Grune J, Rösener N, Weller A, Stangl V, Fisher EA, Stangl K, Ludwig A, Hewing B. Deficiency of inactive rhomboid protein 2 (iRhom2) attenuates diet-induced hyperlipidemia and early atherogenesis. Cardiovasc Res. 2021 Feb 10. PMID: 33576385.
    Citations:    Fields:    
  3. Panizzi P, Krohn-Grimberghe M, Keliher E, Ye YX, Grune J, Frodermann V, Sun Y, Muse CG, Bushey K, Iwamoto Y, van Leent MMT, Meerwaldt A, Toner YC, Munitz J, Maier A, Soultanidis G, Calcagno C, Pérez-Medina C, Carlucci G, Riddell KP, Barney S, Horne G, Anderson B, Maddur-Appajaiah A, Verhamme IM, Bock PE, Wojtkiewicz GR, Courties G, Swirski FK, Church WR, Walz PH, Tillson DM, Mulder WJM, Nahrendorf M. Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis. Sci Transl Med. 2020 11 04; 12(568). PMID: 33148623.
    Citations:    Fields:    
  4. Heinzel FR, Hegemann N, Hohendanner F, Primessnig U, Grune J, Blaschke F, de Boer RA, Pieske B, Schiattarella GG, Kuebler WM. Left ventricular dysfunction in heart failure with preserved ejection fraction-molecular mechanisms and impact on right ventricular function. Cardiovasc Diagn Ther. 2020 Oct; 10(5):1541-1560. PMID: 33224773.
    Citations: 1     
  5. Kräker K, Herse F, Golic M, Reichhart N, Crespo-Garcia S, Strauß O, Grune J, Kintscher U, Ebrahim M, Bader M, Alenina N, Heuser A, Luft FC, Müller DN, Dechend R, Haase N. Effects of empagliflozin and target-organ damage in a novel rodent model of heart failure induced by combined hypertension and diabetes. Sci Rep. 2020 08 20; 10(1):14061. PMID: 32820187.
    Citations:    Fields:    
  6. Szulcek R, Grune J, Kuebler WM. The updated cancer paradigm of PAH: recognizing complexity. Am J Physiol Lung Cell Mol Physiol. 2020 06 01; 318(6):L1111-L1114. PMID: 32320264.
    Citations:    Fields:    Translation:Humans
  7. Pappritz K, Grune J, Klein O, Hegemann N, Dong F, El-Shafeey M, Lin J, Kuebler WM, Kintscher U, Tschöpe C, Van Linthout S. Speckle-tracking echocardiography combined with imaging mass spectrometry assesses region-dependent alterations. Sci Rep. 2020 02 27; 10(1):3629. PMID: 32108156.
    Citations:    Fields:    Translation:HumansAnimals
  8. Grune J, Beyhoff N, Hegemann N, Lauryn JH, Kuebler WM. From bedside to bench: lung ultrasound for the assessment of pulmonary edema in animal models. Cell Tissue Res. 2020 May; 380(2):379-392. PMID: 32009189.
    Citations: 2     Fields:    Translation:HumansAnimals
  9. Lapinskas T, Kelle S, Grune J, Foryst-Ludwig A, Meyborg H, Jeuthe S, Wellnhofer E, Elsanhoury A, Pieske B, Gebker R, Kintscher U, Stawowy P. Serelaxin Improves Regional Myocardial Function in Experimental Heart Failure: An In Vivo Cardiac Magnetic Resonance Study. J Am Heart Assoc. 2020 02 04; 9(3):e013702. PMID: 32000566.
    Citations: 1     Fields:    Translation:Animals
  10. Frodermann V, Rohde D, Courties G, Severe N, Schloss MJ, Amatullah H, McAlpine CS, Cremer S, Hoyer FF, Ji F, van Koeverden ID, Herisson F, Honold L, Masson GS, Zhang S, Grune J, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Lee IH, Gustafsson K, Pasterkamp G, de Jager SCA, Sadreyev RI, MacFadyen J, Libby P, Ridker P, Scadden DT, Naxerova K, Jeffrey KL, Swirski FK, Nahrendorf M. Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells. Nat Med. 2019 11; 25(11):1761-1771. PMID: 31700184.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  11. Grune J, Tabuchi A, Kuebler WM. Alveolar dynamics during mechanical ventilation in the healthy and injured lung. Intensive Care Med Exp. 2019 Jul 25; 7(Suppl 1):34. PMID: 31346797.
    Citations: 11     
  12. Beyhoff N, Lohr D, Foryst-Ludwig A, Klopfleisch R, Brix S, Grune J, Thiele A, Erfinanda L, Tabuchi A, Kuebler WM, Pieske B, Schreiber LM, Kintscher U. Characterization of Myocardial Microstructure and Function in an Experimental Model of Isolated Subendocardial Damage. Hypertension. 2019 08; 74(2):295-304. PMID: 31291149.
    Citations: 2     Fields:    Translation:HumansAnimals
  13. Grune J, Ritter D, Kräker K, Pappritz K, Beyhoff N, Schütte T, Ott C, John C, van Linthout S, Tschöpe C, Dechend R, Muller DN, Haase N, Grune T, Kintscher U, Kuebler WM. Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction. Cardiovasc Ultrasound. 2019 Apr 22; 17(1):7. PMID: 31010431.
    Citations: 2     Fields:    Translation:Animals
  14. John C, Grune J, Ott C, Nowotny K, Deubel S, Kühne A, Schubert C, Kintscher U, Regitz-Zagrosek V, Grune T. Sex Differences in Cardiac Mitochondria in the New Zealand Obese Mouse. Front Endocrinol (Lausanne). 2018; 9:732. PMID: 30564194.
    Citations: 4     
  15. Grune J, Kuebler WM. Is there a role for endothelin-1 receptor antagonists in the treatment of lung fibrosis associated with pulmonary hypertension? Eur Respir J. 2018 08; 52(2). PMID: 30166496.
    Citations: 1     Fields:    Translation:Humans
  16. Grune J, Blumrich A, Brix S, Jeuthe S, Drescher C, Grune T, Foryst-Ludwig A, Messroghli D, Kuebler WM, Ott C, Kintscher U. Evaluation of a commercial multi-dimensional echocardiography technique for ventricular volumetry in small animals. Cardiovasc Ultrasound. 2018 Jul 03; 16(1):10. PMID: 29966517.
    Citations: 6     Fields:    Translation:Animals
  17. Grune J, Beyhoff N, Smeir E, Chudek R, Blumrich A, Ban Z, Brix S, Betz IR, Schupp M, Foryst-Ludwig A, Klopfleisch R, Stawowy P, Houtman R, Kolkhof P, Kintscher U. Selective Mineralocorticoid Receptor Cofactor Modulation as Molecular Basis for Finerenone's Antifibrotic Activity. Hypertension. 2018 04; 71(4):599-608. PMID: 29437893.
    Citations: 14     Fields:    Translation:AnimalsCells
  18. Salatzki J, Foryst-Ludwig A, Bentele K, Blumrich A, Smeir E, Ban Z, Brix S, Grune J, Beyhoff N, Klopfleisch R, Dunst S, Surma MA, Klose C, Rothe M, Heinzel FR, Krannich A, Kershaw EE, Beule D, Schulze PC, Marx N, Kintscher U. Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure. PLoS Genet. 2018 01; 14(1):e1007171. PMID: 29320510.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  19. Beyhoff N, Brix S, Betz IR, Klopfleisch R, Foryst-Ludwig A, Krannich A, Stawowy P, Knebel F, Grune J, Kintscher U. Application of Speckle-Tracking Echocardiography in an Experimental Model of Isolated Subendocardial Damage. J Am Soc Echocardiogr. 2017 Dec; 30(12):1239-1250.e2. PMID: 29066223.
    Citations: 8     Fields:    Translation:Animals
  20. Lapinskas T, Grune J, Zamani SM, Jeuthe S, Messroghli D, Gebker R, Meyborg H, Kintscher U, Zaliunas R, Pieske B, Stawowy P, Kelle S. Cardiovascular magnetic resonance feature tracking in small animals - a preliminary study on reproducibility and sample size calculation. BMC Med Imaging. 2017 08 23; 17(1):51. PMID: 28835220.
    Citations: 7     Fields:    Translation:Animals
  21. Grune J, Meyborg H, Bezhaeva T, Kappert K, Hillmeister P, Kintscher U, Pieske B, Stawowy P. PCSK9 regulates the chemokine receptor CCR2 on monocytes. Biochem Biophys Res Commun. 2017 04 01; 485(2):312-318. PMID: 28232185.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  22. Grune J, Benz V, Brix S, Salatzki J, Blumrich A, Höft B, Klopfleisch R, Foryst-Ludwig A, Kolkhof P, Kintscher U. Steroidal and Nonsteroidal Mineralocorticoid Receptor Antagonists Cause Differential Cardiac Gene Expression in Pressure Overload-induced Cardiac Hypertrophy. J Cardiovasc Pharmacol. 2016 05; 67(5):402-11. PMID: 26859196.
    Citations: 13     Fields:    Translation:Animals
  23. Foryst-Ludwig A, Kreissl MC, Benz V, Brix S, Smeir E, Ban Z, Januszewicz E, Salatzki J, Grune J, Schwanstecher AK, Blumrich A, Schirbel A, Klopfleisch R, Rothe M, Blume K, Halle M, Wolfarth B, Kershaw EE, Kintscher U. Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate. J Biol Chem. 2015 Sep 25; 290(39):23603-15. PMID: 26260790.
    Citations: 14     Fields:    Translation:AnimalsCells
  24. Ebert G, Steininger A, Weißmann R, Boldt V, Lind-Thomsen A, Grune J, Badelt S, Heßler M, Peiser M, Hitzler M, Jensen LR, Müller I, Hu H, Arndt PF, Kuss AW, Tebel K, Ullmann R. Distribution of segmental duplications in the context of higher order chromatin organisation of human chromosome 7. BMC Genomics. 2014 Jun 29; 15:537. PMID: 24973960.
    Citations: 3     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.