Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Jana Grune, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Funk-Hilsdorf TC, Behrens F, Grune J, Simmons S. Dysregulated Immunity in Pulmonary Hypertension: From Companion to Composer. Front Physiol. 2022; 13:819145. PMID: 35250621.
  2. Hannemann C, Schecker JH, Brettschneider A, Grune J, Rösener N, Weller A, Stangl V, Fisher EA, Stangl K, Ludwig A, Hewing B. Deficiency of inactive rhomboid protein 2 (iRhom2) attenuates diet-induced hyperlipidaemia and early atherogenesis. Cardiovasc Res. 2022 01 07; 118(1):156-168. PMID: 33576385.
    Citations: 1     Fields:    Translation:AnimalsCells
  3. Betz IR, Qaiyumi SJ, Goeritzer M, Thiele A, Brix S, Beyhoff N, Grune J, Klopfleisch R, Greulich F, Uhlenhaut NH, Kintscher U, Foryst-Ludwig A. Cardioprotective Effects of Palmitoleic Acid (C16:1n7) in a Mouse Model of Catecholamine-Induced Cardiac Damage Are Mediated by PPAR Activation. Int J Mol Sci. 2021 Nov 24; 22(23). PMID: 34884498.
    Citations:    Fields:    Translation:AnimalsCells
  4. Ott C, Pappritz K, Hegemann N, John C, Jeuthe S, McAlpine CS, Iwamoto Y, Lauryn JH, Klages J, Klopfleisch R, Van Linthout S, Swirski F, Nahrendorf M, Kintscher U, Grune T, Kuebler WM, Grune J. Spontaneous Degenerative Aortic Valve Disease in New Zealand Obese Mice. J Am Heart Assoc. 2021 12 07; 10(23):e023131. PMID: 34779224.
    Citations:    Fields:    
  5. Grimmer B, Krauszman A, Hu X, Kabir G, Connelly KA, Li M, Grune J, Madry C, Isakson BE, Kuebler WM. Pannexin 1-a novel regulator of acute hypoxic pulmonary vasoconstriction. Cardiovasc Res. 2021 Oct 20. PMID: 34668529.
    Citations: 1     Fields:    
  6. Ritter D, Goeritzer M, Thiele A, Blumrich A, Beyhoff N, Luettges K, Smeir E, Kasch J, Grune J, Müller OJ, Klopfleisch R, Jaeger C, Foryst-Ludwig A, Kintscher U. Liver X Receptor Agonist AZ876 Induces Beneficial Endogenous Cardiac Lipid Reprogramming and Protects Against Isoproterenol-Induced Cardiac Damage. J Am Heart Assoc. 2021 07 20; 10(14):e019473. PMID: 34227403.
    Citations: 1     Fields:    Translation:Animals
  7. Thiele A, Luettges K, Ritter D, Beyhoff N, Smeir E, Grune J, Steinhoff JS, Schupp M, Klopfleisch R, Rothe M, Wilck N, Bartolomaeus H, Migglautsch AK, Breinbauer R, Kershaw EE, Grabner GF, Zechner R, Kintscher U, Foryst-Ludwig A. Pharmacological inhibition of adipose tissue Adipose Triglyceride Lipase (ATGL) by Atglistatin prevents catecholamine-induced myocardial damage. Cardiovasc Res. 2021 Jun 01. PMID: 34061169.
    Citations: 1     Fields:    
  8. Lerchbaumer MH, Lauryn JH, Bachmann U, Enghard P, Fischer T, Grune J, Hegemann N, Khadzhynov D, Kruse JM, Lehner LJ, Lindner T, Oezkan T, Zickler D, Kuebler WM, Hamm B, Eckardt KU, Muench F. Point-of-care lung ultrasound in COVID-19 patients: inter- and intra-observer agreement in a prospective observational study. Sci Rep. 2021 05 21; 11(1):10678. PMID: 34021219.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  9. Hegemann N, Primessnig U, Bode D, Wakula P, Beindorff N, Klopfleisch R, Michalick L, Grune J, Hohendanner F, Messroghli D, Pieske B, Kuebler WM, Heinzel FR. Right-ventricular dysfunction in HFpEF is linked to altered cardiomyocyte Ca2+ homeostasis and myofilament sensitivity. ESC Heart Fail. 2021 08; 8(4):3130-3144. PMID: 34002482.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  10. Ott C, Jung T, Brix S, John C, Betz IR, Foryst-Ludwig A, Deubel S, Kuebler WM, Grune T, Kintscher U, Grune J. Hypertrophy-Reduced Autophagy Causes Cardiac Dysfunction by Directly Impacting Cardiomyocyte Contractility. Cells. 2021 04 04; 10(4). PMID: 33916597.
    Citations: 1     Fields:    Translation:AnimalsCells
  11. Blumrich A, Vogler G, Dresen S, Diop SB, Jaeger C, Leberer S, Grune J, Wirth EK, Hoeft B, Renko K, Foryst-Ludwig A, Spranger J, Sigrist S, Bodmer R, Kintscher U. Fat-body brummer lipase determines survival and cardiac function during starvation in Drosophila melanogaster. iScience. 2021 Apr 23; 24(4):102288. PMID: 33889813.
    Citations: 2     
  12. Grune J, Yamazoe M, Nahrendorf M. Electroimmunology and cardiac arrhythmia. Nat Rev Cardiol. 2021 08; 18(8):547-564. PMID: 33654273.
    Citations: 3     Fields:    Translation:Humans
  13. Panizzi P, Krohn-Grimberghe M, Keliher E, Ye YX, Grune J, Frodermann V, Sun Y, Muse CG, Bushey K, Iwamoto Y, van Leent MMT, Meerwaldt A, Toner YC, Munitz J, Maier A, Soultanidis G, Calcagno C, Pérez-Medina C, Carlucci G, Riddell KP, Barney S, Horne G, Anderson B, Maddur-Appajaiah A, Verhamme IM, Bock PE, Wojtkiewicz GR, Courties G, Swirski FK, Church WR, Walz PH, Tillson DM, Mulder WJM, Nahrendorf M. Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis. Sci Transl Med. 2020 11 04; 12(568). PMID: 33148623.
    Citations: 1     Fields:    Translation:AnimalsCells
  14. Heinzel FR, Hegemann N, Hohendanner F, Primessnig U, Grune J, Blaschke F, de Boer RA, Pieske B, Schiattarella GG, Kuebler WM. Left ventricular dysfunction in heart failure with preserved ejection fraction-molecular mechanisms and impact on right ventricular function. Cardiovasc Diagn Ther. 2020 Oct; 10(5):1541-1560. PMID: 33224773.
    Citations: 3     
  15. Kräker K, Herse F, Golic M, Reichhart N, Crespo-Garcia S, Strauß O, Grune J, Kintscher U, Ebrahim M, Bader M, Alenina N, Heuser A, Luft FC, Müller DN, Dechend R, Haase N. Effects of empagliflozin and target-organ damage in a novel rodent model of heart failure induced by combined hypertension and diabetes. Sci Rep. 2020 08 20; 10(1):14061. PMID: 32820187.
    Citations:    Fields:    Translation:HumansAnimals
  16. Szulcek R, Grune J, Kuebler WM. The updated cancer paradigm of PAH: recognizing complexity. Am J Physiol Lung Cell Mol Physiol. 2020 06 01; 318(6):L1111-L1114. PMID: 32320264.
    Citations: 1     Fields:    Translation:Humans
  17. Pappritz K, Grune J, Klein O, Hegemann N, Dong F, El-Shafeey M, Lin J, Kuebler WM, Kintscher U, Tschöpe C, Van Linthout S. Speckle-tracking echocardiography combined with imaging mass spectrometry assesses region-dependent alterations. Sci Rep. 2020 02 27; 10(1):3629. PMID: 32108156.
    Citations: 1     Fields:    Translation:HumansAnimals
  18. Grune J, Beyhoff N, Hegemann N, Lauryn JH, Kuebler WM. From bedside to bench: lung ultrasound for the assessment of pulmonary edema in animal models. Cell Tissue Res. 2020 May; 380(2):379-392. PMID: 32009189.
    Citations: 4     Fields:    Translation:HumansAnimals
  19. Lapinskas T, Kelle S, Grune J, Foryst-Ludwig A, Meyborg H, Jeuthe S, Wellnhofer E, Elsanhoury A, Pieske B, Gebker R, Kintscher U, Stawowy P. Serelaxin Improves Regional Myocardial Function in Experimental Heart Failure: An In Vivo Cardiac Magnetic Resonance Study. J Am Heart Assoc. 2020 02 04; 9(3):e013702. PMID: 32000566.
    Citations: 1     Fields:    Translation:Animals
  20. Frodermann V, Rohde D, Courties G, Severe N, Schloss MJ, Amatullah H, McAlpine CS, Cremer S, Hoyer FF, Ji F, van Koeverden ID, Herisson F, Honold L, Masson GS, Zhang S, Grune J, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Lee IH, Gustafsson K, Pasterkamp G, de Jager SCA, Sadreyev RI, MacFadyen J, Libby P, Ridker P, Scadden DT, Naxerova K, Jeffrey KL, Swirski FK, Nahrendorf M. Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells. Nat Med. 2019 11; 25(11):1761-1771. PMID: 31700184.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  21. Grune J, Tabuchi A, Kuebler WM. Alveolar dynamics during mechanical ventilation in the healthy and injured lung. Intensive Care Med Exp. 2019 Jul 25; 7(Suppl 1):34. PMID: 31346797.
    Citations: 15     
  22. Beyhoff N, Lohr D, Foryst-Ludwig A, Klopfleisch R, Brix S, Grune J, Thiele A, Erfinanda L, Tabuchi A, Kuebler WM, Pieske B, Schreiber LM, Kintscher U. Characterization of Myocardial Microstructure and Function in an Experimental Model of Isolated Subendocardial Damage. Hypertension. 2019 08; 74(2):295-304. PMID: 31291149.
    Citations: 8     Fields:    Translation:HumansAnimals
  23. Grune J, Ritter D, Kräker K, Pappritz K, Beyhoff N, Schütte T, Ott C, John C, van Linthout S, Tschöpe C, Dechend R, Muller DN, Haase N, Grune T, Kintscher U, Kuebler WM. Accurate assessment of LV function using the first automated 2D-border detection algorithm for small animals - evaluation and application to models of LV dysfunction. Cardiovasc Ultrasound. 2019 Apr 22; 17(1):7. PMID: 31010431.
    Citations: 3     Fields:    Translation:Animals
  24. John C, Grune J, Ott C, Nowotny K, Deubel S, Kühne A, Schubert C, Kintscher U, Regitz-Zagrosek V, Grune T. Sex Differences in Cardiac Mitochondria in the New Zealand Obese Mouse. Front Endocrinol (Lausanne). 2018; 9:732. PMID: 30564194.
    Citations: 6     Fields:    
  25. Grune J, Kuebler WM. Is there a role for endothelin-1 receptor antagonists in the treatment of lung fibrosis associated with pulmonary hypertension? Eur Respir J. 2018 08; 52(2). PMID: 30166496.
    Citations: 2     Fields:    Translation:Humans
  26. Grune J, Blumrich A, Brix S, Jeuthe S, Drescher C, Grune T, Foryst-Ludwig A, Messroghli D, Kuebler WM, Ott C, Kintscher U. Evaluation of a commercial multi-dimensional echocardiography technique for ventricular volumetry in small animals. Cardiovasc Ultrasound. 2018 Jul 03; 16(1):10. PMID: 29966517.
    Citations: 12     Fields:    Translation:Animals
  27. Grune J, Beyhoff N, Smeir E, Chudek R, Blumrich A, Ban Z, Brix S, Betz IR, Schupp M, Foryst-Ludwig A, Klopfleisch R, Stawowy P, Houtman R, Kolkhof P, Kintscher U. Selective Mineralocorticoid Receptor Cofactor Modulation as Molecular Basis for Finerenone's Antifibrotic Activity. Hypertension. 2018 04; 71(4):599-608. PMID: 29437893.
    Citations: 28     Fields:    Translation:AnimalsCells
  28. Salatzki J, Foryst-Ludwig A, Bentele K, Blumrich A, Smeir E, Ban Z, Brix S, Grune J, Beyhoff N, Klopfleisch R, Dunst S, Surma MA, Klose C, Rothe M, Heinzel FR, Krannich A, Kershaw EE, Beule D, Schulze PC, Marx N, Kintscher U. Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure. PLoS Genet. 2018 01; 14(1):e1007171. PMID: 29320510.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  29. Beyhoff N, Brix S, Betz IR, Klopfleisch R, Foryst-Ludwig A, Krannich A, Stawowy P, Knebel F, Grune J, Kintscher U. Application of Speckle-Tracking Echocardiography in an Experimental Model of Isolated Subendocardial Damage. J Am Soc Echocardiogr. 2017 Dec; 30(12):1239-1250.e2. PMID: 29066223.
    Citations: 16     Fields:    Translation:Animals
  30. Lapinskas T, Grune J, Zamani SM, Jeuthe S, Messroghli D, Gebker R, Meyborg H, Kintscher U, Zaliunas R, Pieske B, Stawowy P, Kelle S. Cardiovascular magnetic resonance feature tracking in small animals - a preliminary study on reproducibility and sample size calculation. BMC Med Imaging. 2017 08 23; 17(1):51. PMID: 28835220.
    Citations: 10     Fields:    Translation:Animals
  31. Grune J, Meyborg H, Bezhaeva T, Kappert K, Hillmeister P, Kintscher U, Pieske B, Stawowy P. PCSK9 regulates the chemokine receptor CCR2 on monocytes. Biochem Biophys Res Commun. 2017 04 01; 485(2):312-318. PMID: 28232185.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  32. Grune J, Benz V, Brix S, Salatzki J, Blumrich A, Höft B, Klopfleisch R, Foryst-Ludwig A, Kolkhof P, Kintscher U. Steroidal and Nonsteroidal Mineralocorticoid Receptor Antagonists Cause Differential Cardiac Gene Expression in Pressure Overload-induced Cardiac Hypertrophy. J Cardiovasc Pharmacol. 2016 05; 67(5):402-11. PMID: 26859196.
    Citations: 18     Fields:    Translation:Animals
  33. Foryst-Ludwig A, Kreissl MC, Benz V, Brix S, Smeir E, Ban Z, Januszewicz E, Salatzki J, Grune J, Schwanstecher AK, Blumrich A, Schirbel A, Klopfleisch R, Rothe M, Blume K, Halle M, Wolfarth B, Kershaw EE, Kintscher U. Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate. J Biol Chem. 2015 Sep 25; 290(39):23603-15. PMID: 26260790.
    Citations: 24     Fields:    Translation:AnimalsCells
  34. Ebert G, Steininger A, Weißmann R, Boldt V, Lind-Thomsen A, Grune J, Badelt S, Heßler M, Peiser M, Hitzler M, Jensen LR, Müller I, Hu H, Arndt PF, Kuss AW, Tebel K, Ullmann R. Distribution of segmental duplications in the context of higher order chromatin organisation of human chromosome 7. BMC Genomics. 2014 Jun 29; 15:537. PMID: 24973960.
    Citations: 3     Fields:    Translation:HumansCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Grune's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (161)
Co-Authors (11)
Similar People (60)
Same Department 
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.