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Gurol Tuncman, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tirosh A, Tuncman G, Calay ES, Rathaus M, Ron I, Tirosh A, Yalcin A, Lee YG, Livne R, Ron S, Minsky N, Arruda AP, Hotamisligil GS. Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism. Cell Metab. 2021 Aug 03; 33(8):1716. PMID: 34348100.
    Citations: 2     Fields:    
  2. Tirosh A, Tuncman G, Calay ES, Rathaus M, Ron I, Tirosh A, Yalcin A, Lee YG, Livne R, Ron S, Minsky N, Arruda AP, Hotamisligil GS. Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism. Cell Metab. 2021 02 02; 33(2):319-333.e6. PMID: 33340456; PMCID: PMC7858244.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  3. Tirosh A, Calay ES, Tuncman G, Claiborn KC, Inouye KE, Eguchi K, Alcala M, Rathaus M, Hollander KS, Ron I, Livne R, Heianza Y, Qi L, Shai I, Garg R, Hotamisligil GS. The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans. Sci Transl Med. 2019 04 24; 11(489). PMID: 31019023.
    Citations: 57     Fields:    Translation:HumansAnimals
  4. Burak MF, Inouye KE, White A, Lee A, Tuncman G, Calay ES, Sekiya M, Tirosh A, Eguchi K, Birrane G, Lightwood D, Howells L, Odede G, Hailu H, West S, Garlish R, Neale H, Doyle C, Moore A, Hotamisligil GS. Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes. Sci Transl Med. 2015 Dec 23; 7(319):319ra205. PMID: 26702093.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  5. Cao H, Sekiya M, Ertunc ME, Burak MF, Mayers JR, White A, Inouye K, Rickey LM, Ercal BC, Furuhashi M, Tuncman G, Hotamisligil GS. Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production. Cell Metab. 2013 May 07; 17(5):768-78. PMID: 23663740.
    Citations: 102     Fields:    Translation:AnimalsCells
  6. Nakamura T, Furuhashi M, Li P, Cao H, Tuncman G, Sonenberg N, Gorgun CZ, Hotamisligil GS. Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis. Cell. 2010 Feb 05; 140(3):338-48. PMID: 20144759.
    Citations: 214     Fields:    Translation:HumansAnimals
  7. Furuhashi M, Fucho R, Görgün CZ, Tuncman G, Cao H, Hotamisligil GS. Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice. J Clin Invest. 2008 Jul; 118(7):2640-50. PMID: 18551191; PMCID: PMC2423863.
    Citations: 149     Fields:    Translation:AnimalsCells
  8. Furuhashi M, Tuncman G, Görgün CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS. Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature. 2007 Jun 21; 447(7147):959-65. PMID: 17554340.
    Citations: 259     Fields:    Translation:HumansAnimalsCells
  9. Tuncman G, Hirosumi J, Solinas G, Chang L, Karin M, Hotamisligil GS. Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. Proc Natl Acad Sci U S A. 2006 Jul 11; 103(28):10741-6. PMID: 16818881; PMCID: PMC1487172.
    Citations: 136     Fields:    Translation:HumansAnimalsCells
  10. Tuncman G, Erbay E, Hom X, De Vivo I, Campos H, Rimm EB, Hotamisligil GS. A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease. Proc Natl Acad Sci U S A. 2006 May 02; 103(18):6970-5. PMID: 16641093.
    Citations: 98     Fields:    Translation:HumansAnimalsCells
  11. Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Görgün C, Glimcher LH, Hotamisligil GS. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science. 2004 Oct 15; 306(5695):457-61. PMID: 15486293.
    Citations: 1463     Fields:    Translation:AnimalsCells
  12. Pandey M, Tuncman G, Hotamisligil GS, Samad F. Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1. Am J Pathol. 2003 Mar; 162(3):933-41. PMID: 12598326; PMCID: PMC1868101.
    Citations: 11     Fields:    Translation:AnimalsCells
  13. Hirosumi J, Tuncman G, Chang L, Görgün CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS. A central role for JNK in obesity and insulin resistance. Nature. 2002 Nov 21; 420(6913):333-6. PMID: 12447443.
    Citations: 1178     Fields:    Translation:AnimalsCells
  14. Peller S, Yona R, Kopilova Y, Prokocimer M, Goldfinger N, Uysal A, Karabulut HG, Tukun A, Bokesoy I, Tuncman G, Rotter V. Molecular alterations in the TP53 gene of peripheral blood cells of patients with chronic myeloid leukemia. Genes Chromosomes Cancer. 1998 Jan; 21(1):2-7. PMID: 9443036.
    Citations: 4     Fields:    Translation:HumansCells
  15. Ali M, Tunçman G, Cross NC, Vidailhet M, Bökesoy I, Gitzelmann R, Cox TM. Null alleles of the aldolase B gene in patients with hereditary fructose intolerance. J Med Genet. 1994 Jun; 31(6):499-503. PMID: 8071980; PMCID: PMC1049933.
    Citations: 5     Fields:    Translation:HumansCells
  16. Tunçman G, Tükün A, Yalaz K, Bökesoy I. A case of Prader Willi syndrome with del 15 (q11-->q13). Turk J Pediatr. 1993 Oct-Dec; 35(4):333-6. PMID: 8160287.
    Citations:    Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.