Harvard Catalyst Profiles

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Koen Breyne, D.P.H.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Nieland L, Mahjoum S, Grandell E, Breyne K, Breakefield XO. Engineered EVs designed to target diseases of the CNS. J Control Release. 2023 Mar 15; 356:493-506. PMID: 36907561.
    Citations:    Fields:    
  2. Rufino-Ramos D, Leandro K, Perdigão PRL, O'Brien K, Pinto MM, Santana MM, van Solinge TS, Mahjoum S, Breakefield XO, Breyne K, de Almeida LP. Extracellular communication between brain cells through functional transfer of Cre mRNA. bioRxiv. 2023 Jan 31. PMID: 36811091; PMCID: PMC9942248.
  3. Walachowski S, Breyne K, Secher T, Cougoule C, Guzylack-Piriou L, Meyer E, Foucras G, Tabouret G. Oral supplementation with yeast ß-glucans improves the resolution of Escherichia coli-associated inflammatory responses independently of monocyte/macrophage immune training. Front Immunol. 2022; 13:1086413. PMID: 36605196; PMCID: PMC9809295.
    Citations:    Fields:    Translation:AnimalsCells
  4. Breyne K, Ughetto S, Rufino-Ramos D, Mahjoum S, Grandell EA, de Almeida LP, Breakefield XO. Exogenous loading of extracellular vesicles, virus-like particles, and lentiviral vectors with supercharged proteins. Commun Biol. 2022 05 19; 5(1):485. PMID: 35590035; PMCID: PMC9120435.
    Citations: 3     Translation:AnimalsCells
  5. Aldoghachi AF, Aldoghachi AF, Breyne K, Ling KH, Cheah PS. Recent Advances in the Therapeutic Strategies of Glioblastoma Multiforme. Neuroscience. 2022 05 21; 491:240-270. PMID: 35395355.
    Citations: 2     Fields:    Translation:HumansCells
  6. Rufino-Ramos D, Lule S, Mahjoum S, Ughetto S, Cristopher Bragg D, Pereira de Almeida L, Breakefield XO, Breyne K. Using genetically modified extracellular vesicles as a non-invasive strategy to evaluate brain-specific cargo. Biomaterials. 2022 02; 281:121366. PMID: 35033904; PMCID: PMC8886823.
    Citations: 5     Fields:    Translation:AnimalsCells
  7. Chandler M, Johnson B, Khisamutdinov E, Dobrovolskaia MA, Sztuba-Solinska J, Salem AK, Breyne K, Chammas R, Walter NG, Contreras LM, Guo P, Afonin KA. The International Society of RNA Nanotechnology and Nanomedicine (ISRNN): The Present and Future of the Burgeoning Field. ACS Nano. 2021 11 23; 15(11):16957-16973. PMID: 34677049; PMCID: PMC9023608.
    Citations: 5     Fields:    Translation:Humans
  8. Vander Elst N, Breyne K, Steenbrugge J, Gibson AJ, Smith DGE, Germon P, Werling D, Meyer E. Enterobactin Deficiency in a Coliform Mastitis Isolate Decreases Its Fitness in a Murine Model: A Preliminary Host-Pathogen Interaction Study. Front Vet Sci. 2020; 7:576583. PMID: 33240956.
    Citations: 1     
  9. O'Brien K, Breyne K, Ughetto S, Laurent LC, Breakefield XO. RNA delivery by extracellular vesicles in mammalian cells and its applications. Nat Rev Mol Cell Biol. 2020 10; 21(10):585-606. PMID: 32457507; PMCID: PMC7249041.
    Citations: 426     Fields:    Translation:HumansAnimalsCells
  10. Tartaglia NR, Breyne K, Meyer E, Cauty C, Jardin J, Chrétien D, Dupont A, Demeyere K, Berkova N, Azevedo V, Guédon E, Le Loir Y. Staphylococcus aureus Extracellular Vesicles Elicit an Immunostimulatory Response in vivo on the Murine Mammary Gland. Front Cell Infect Microbiol. 2018; 8:277. PMID: 30186772.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  11. Steenbrugge J, Breyne K, Demeyere K, De Wever O, Sanders NN, Van Den Broeck W, Colpaert C, Vermeulen P, Van Laere S, Meyer E. Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer. J Exp Clin Cancer Res. 2018 Aug 15; 37(1):191. PMID: 30111338; PMCID: PMC6094904.
    Citations: 23     Fields:    Translation:AnimalsCells
  12. Breyne K, Steenbrugge J, Demeyere K, Lee CG, Elias JA, Petzl W, Smith DGE, Germon P, Meyer E. Immunomodulation of Host Chitinase 3-Like 1 During a Mammary Pathogenic Escherichia coli Infection. Front Immunol. 2018; 9:1143. PMID: 29892291.
    Citations: 5     Fields:    Translation:AnimalsCells
  13. Breyne K, Honaker RW, Hobbs Z, Richter M, Zaczek M, Spangler T, Steenbrugge J, Lu R, Kinkhabwala A, Marchon B, Meyer E, Mokres L. Efficacy and Safety of a Bovine-Associated Staphylococcus aureus Phage Cocktail in a Murine Model of Mastitis. Front Microbiol. 2017; 8:2348. PMID: 29234314; PMCID: PMC5712351.
    Citations: 23     
  14. Breyne K, Steenbrugge J, Demeyere K, Vanden Berghe T, Meyer E. Preconditioning with Lipopolysaccharide or Lipoteichoic Acid Protects against Staphylococcus aureus Mammary Infection in Mice. Front Immunol. 2017; 8:833. PMID: 28791009.
    Citations: 11     Fields:    
  15. Steenbrugge J, Breyne K, Denies S, Dekimpe M, Demeyere K, De Wever O, Vermeulen P, Van Laere S, Sanders NN, Meyer E. Comparison of the Adipose and Luminal Mammary Gland Compartment as Orthotopic Inoculation Sites in a 4T1-Based Immunocompetent Preclinical Model for Triple-Negative Breast Cancer. J Mammary Gland Biol Neoplasia. 2016 12; 21(3-4):113-122. PMID: 27714576.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  16. Vermote A, Brackman G, Risseeuw MD, Vanhoutte B, Cos P, Van Hecke K, Breyne K, Meyer E, Coenye T, Van Calenbergh S. Hamamelitannin Analogues that Modulate Quorum Sensing as Potentiators of Antibiotics against Staphylococcus aureus. Angew Chem Int Ed Engl. 2016 05 23; 55(22):6551-5. PMID: 27095479.
    Citations: 15     Fields:    Translation:Cells
  17. Peton V, Breyne K, Rault L, Demeyere K, Berkova N, Meyer E, Even S, Le Loir Y. Disruption of the sigS gene attenuates the local innate immune response to Staphylococcus aureus in a mouse mastitis model. Vet Microbiol. 2016 Apr 15; 186:44-51. PMID: 27016756.
    Citations: 4     Fields:    Translation:AnimalsCells
  18. Brackman G, Breyne K, De Rycke R, Vermote A, Van Nieuwerburgh F, Meyer E, Van Calenbergh S, Coenye T. The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release. Sci Rep. 2016 Feb 01; 6:20321. PMID: 26828772.
    Citations: 54     Fields:    Translation:Cells
  19. Breyne K, De Vliegher S, De Visscher A, Piepers S, Meyer E. Technical note: a pilot study using a mouse mastitis model to study differences between bovine associated coagulase-negative staphylococci. J Dairy Sci. 2015 Feb; 98(2):1090-100. PMID: 25497801.
    Citations: 11     Fields:    Translation:AnimalsCells
  20. Breyne K, Cool SK, Demon D, Demeyere K, Vandenberghe T, Vandenabeele P, Carlsen H, Van Den Broeck W, Sanders NN, Meyer E. Non-classical proIL-1beta activation during mammary gland infection is pathogen-dependent but caspase-1 independent. PLoS One. 2014; 9(8):e105680. PMID: 25162221.
    Citations: 14     Fields:    Translation:AnimalsCells
  21. Demon D, Breyne K, Schiffer G, Meyer E. Short communication: Antimicrobial efficacy of intramammary treatment with a novel biphenomycin compound against Staphylococcus aureus, Streptococcus uberis, and Escherichia coli-induced mouse mastitis. J Dairy Sci. 2013; 96(11):7082-7087. PMID: 24054294.
    Citations: 7     Fields:    Translation:AnimalsCells
  22. Cool SK, Breyne K, Meyer E, De Smedt SC, Sanders NN. Comparison of in vivo optical systems for bioluminescence and fluorescence imaging. J Fluoresc. 2013 Sep; 23(5):909-20. PMID: 23579930.
    Citations: 16     Fields:    Translation:AnimalsCells
  23. Demeyere K, Remijsen Q, Demon D, Breyne K, Notebaert S, Boyen F, Guérin CJ, Vandenabeele P, Meyer E. Escherichia coli induces bovine neutrophil cell death independent from caspase-3/-7/-1, but with phosphatidylserine exposure prior to membrane rupture. Vet Immunol Immunopathol. 2013 May 15; 153(1-2):45-56. PMID: 23510559.
    Citations: 6     Fields:    Translation:AnimalsCells
  24. Demon D, Ludwig C, Breyne K, Guédé D, Dörner JC, Froyman R, Meyer E. The intramammary efficacy of first generation cephalosporins against Staphylococcus aureus mastitis in mice. Vet Microbiol. 2012 Nov 09; 160(1-2):141-50. PMID: 22677480.
    Citations: 11     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.