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Jingjing Chen, Ph.D.

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Biography
Institute of Oncology Research (IOR), Faculty of Biology and Medicine, University of Lausanne, Bellinzona, SwitzerlandPh.D.3/2018Life Sciences
Second Military Medical University, Shanghai, ChinaMasters07/2008Oncology
East China University of Science and Technology, Shanghai, ChinaBachelor07/2003Biotechnology
2019
Pfizer Research Award in Oncology, Pfizer Research Prize Foundation
2019
Prix de la Faculté de biologie et de médecine, University of Lausanne
2019 - 2020
Early Postdoc.Mobility Fellowship, Swiss National Science Foundation
2018
Award of the Best Publication, the 8th Giornata della Ricerca della Svizzera Italiana
2013
IBSA Foundation Fellowship Award for Scientific Research, IBSA Foundation

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P2LAP3_184040 (Jingjing Chen) Feb 1, 2019 - Aug 31, 2020
    Swiss National Science Foundation
    Tumour Derived Vaccine Adjuvants for Advanced Cancers
    Role Description: The overall goal of the project is to develop a novel approach of tumour derived vaccine adjuvants for cancer immunotherapy. The proposal leverages on the key findings on the involvement of the nucleic acids including noncoding RNA in innate immunity and the facts that chemical synthesized, or bacterial nucleic acid vaccine adjuvants elicited striking tumor suppression. These discoveries shed the light that aberrantly expressed non-coding RNA initiated upon chromosome damage due to the replicative stress during the cancer progression or genotoxic agent treatment could potentially trigger cancer cell-autonomous innate immunity for anti-cancer therapy. This proposal will take advantage of CRISPR activation screen platform, etc to investigate whether boosting the expression of tumour derived non-coding RNAs striving in genomic integrity maintenance in advanced cancers will make cancer cells self-exposed to or ‘visualized’ by innate immune surveillance and this novel noncoding RNA adjuvant may represent a breakthrough for the therapeutic vaccination against cancer.
    Role: Research Fellow

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.