Harvard Catalyst Profiles

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Saurja DasGupta, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Weiss Z, DasGupta S. REVERSE: a user-friendly web server for analyzing next-generation sequencing data from in vitro selection/evolution experiments. Nucleic Acids Res. 2022 Jun 14. PMID: 35699225; PMCID: PMC9252737.
    Citations:    Fields:    
  2. Radakovic A, DasGupta S, Wright TH, Aitken HRM, Szostak JW. Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides. Proc Natl Acad Sci U S A. 2022 02 15; 119(7). PMID: 35140183; PMCID: PMC8851484.
    Citations: 1     Fields:    Translation:Cells
  3. Krochmal D, Shao Y, Li NS, DasGupta S, Shelke SA, Koirala D, Piccirilli JA. Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nat Chem Biol. 2022 04; 18(4):376-384. PMID: 35058645.
    Citations: 1     Fields:    Translation:Cells
  4. DasGupta S, Nykiel K, Piccirilli JA. The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes. RNA. 2021 09; 27(9):1017-1024. PMID: 34131025; PMCID: PMC8370743.
    Citations: 2     Fields:    Translation:Cells
  5. DasGupta S, Piccirilli JA. The Varkud Satellite Ribozyme: A Thirty-Year Journey through Biochemistry, Crystallography, and Computation. Acc Chem Res. 2021 06 01; 54(11):2591-2602. PMID: 33974386.
    Citations:    Fields:    Translation:Cells
  6. DasGupta S. Molecular crowding and RNA catalysis. Org Biomol Chem. 2020 10 14; 18(39):7724-7739. PMID: 32914154.
    Citations: 5     Fields:    
  7. Walton T, DasGupta S, Duzdevich D, Oh SS, Szostak JW. In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole-activated substrates. Proc Natl Acad Sci U S A. 2020 03 17; 117(11):5741-5748. PMID: 32123094.
    Citations: 7     Fields:    Translation:Cells
  8. Hoshika S, Leal NA, Kim MJ, Kim MS, Karalkar NB, Kim HJ, Bates AM, Watkins NE, SantaLucia HA, Meyer AJ, DasGupta S, Piccirilli JA, Ellington AD, SantaLucia J, Georgiadis MM, Benner SA. Hachimoji DNA and RNA: A genetic system with eight building blocks. Science. 2019 02 22; 363(6429):884-887. PMID: 30792304.
    Citations: 79     Fields:    Translation:Cells
  9. Koirala D, Shelke SA, Dupont M, Ruiz S, DasGupta S, Bailey LJ, Benner SA, Piccirilli JA. Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography. Nucleic Acids Res. 2018 03 16; 46(5):2624-2635. PMID: 29309709; PMCID: PMC5861428.
    Citations: 8     Fields:    Translation:Cells
  10. DasGupta S, Suslov NB, Piccirilli JA. Structural Basis for Substrate Helix Remodeling and Cleavage Loop Activation in the Varkud Satellite Ribozyme. J Am Chem Soc. 2017 07 19; 139(28):9591-9597. PMID: 28625058; PMCID: PMC5929484.
    Citations: 9     Fields:    Translation:Cells
  11. Biondi E, Lane JD, Das D, Dasgupta S, Piccirilli JA, Hoshika S, Bradley KM, Krantz BA, Benner SA. Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen. Nucleic Acids Res. 2016 Nov 16; 44(20):9565-9577. PMID: 27701076; PMCID: PMC5175368.
    Citations: 18     Fields:    Translation:Cells
  12. Suslov NB, DasGupta S, Huang H, Fuller JR, Lilley DM, Rice PA, Piccirilli JA. Crystal structure of the Varkud satellite ribozyme. Nat Chem Biol. 2015 Nov; 11(11):840-6. PMID: 26414446; PMCID: PMC4618023.
    Citations: 54     Fields:    Translation:AnimalsCells
  13. DasGupta S, Shelke SA, Li NS, Piccirilli JA. Spinach RNA aptamer detects lead(II) with high selectivity. Chem Commun (Camb). 2015 May 28; 51(43):9034-7. PMID: 25940073; PMCID: PMC4755583.
    Citations: 9     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.