Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Edit functionality is currently unavailable.

Prakash Kharel, Ph.D.

Title
Institution
Department
Address
Phone

Biography
Kent State University, OH, USAPh.D.10/2018Biochemistry
Tribhuvan University, Kathmandu, NepalM.Sc.2010Chemistry
Tribhuvan University, Kathmandu, NepalB.Sc.2006Chemistry and Biology

Overview
RNA biology/biochemistry, Neurological disorders.

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lyons SM, Kharel P, Akiyama Y, Ojha S, Dave D, Tsvetkov V, Merrick W, Ivanov P, Anderson P. eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function. Nucleic Acids Res. 2020 06 19; 48(11):6223-6233. PMID: 32374873.
    Citations:    
  2. Mineo M, Lyons SM, Zdioruk M, von Spreckelsen N, Ferrer-Luna R, Ito H, Alayo QA, Kharel P, Giantini Larsen A, Fan WY, Auduong S, Grauwet K, Passaro C, Khalsa JK, Shah K, Reardon DA, Ligon KL, Beroukhim R, Nakashima H, Ivanov P, Anderson PJ, Lawler SE, Chiocca EA. Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus. Mol Cell. 2020 06 18; 78(6):1207-1223.e8. PMID: 32504554.
    Citations:    
  3. Akiyama Y, Kharel P, Abe T, Anderson P, Ivanov P. Isolation and initial structure-functional characterization of endogenous tRNA-derived stress-induced RNAs. RNA Biol. 2020 08; 17(8):1116-1124. PMID: 32116132.
    Citations:    
  4. Kharel P, Balaratnam S, Beals N, Basu S. The role of RNA G-quadruplexes in human diseases and therapeutic strategies. Wiley Interdiscip Rev RNA. 2020 01; 11(1):e1568. PMID: 31514263.
    Citations:    
  5. Mirihana Arachchilage G, Kharel P, Reid J, Basu S. Targeting of G-Quadruplex Harboring Pre-miRNA 92b by LNA Rescues PTEN Expression in NSCL Cancer Cells. ACS Chem Biol. 2018 04 20; 13(4):909-914. PMID: 29529863.
    Citations:    Fields:    
  6. Bhattacharyya D, Morris MJ, Kharel P, Mirihana Arachchilage G, Fedeli KM, Basu S. Engineered domain swapping indicates context dependent functional role of RNA G-quadruplexes. Biochimie. 2017 Jun; 137:147-150. PMID: 28322930.
    Citations: 1     Fields:    Translation:HumansCells
  7. Gibbons BA, Kharel P, Robinson LC, Synowicki RA, Model MA. Volume measurements and fluorescent staining indicate an increase in permeability for organic cation transporter substrates during apoptosis. Exp Cell Res. 2016 05 15; 344(1):112-119. PMID: 26997529.
    Citations:    Fields:    Translation:HumansCells
  8. Kharel P, McDonough J, Basu S. Evidence of extensive RNA oxidation in normal appearing cortex of multiple sclerosis brain. Neurochem Int. 2016 Jan; 92:43-8. PMID: 26706235.
    Citations: 2     Fields:    Translation:HumansCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Kharel's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (63)
Explore
_
Co-Authors (13)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.