Harvard Catalyst Profiles

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Bradley Nelson Martin, Ph.D., M.D.


Case Western Reserve University School of MedicineMD06/2017Medicine
Cleveland Clinic Lerner College of MedicinePhD06/2017Immunology
Brigham and Women's Hospital06/2020Residency (Internal Medicine)

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Du Y, Peng Q, Cheng D, Pan T, Sun W, Wang H, Ma X, He R, Zhang H, Cui Z, Feng X, Liu Z, Zhao T, Hu W, Shen L, Jiang W, Gao N, Martin BN, Zhang CJ, Zhang Z, Wang C. Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing ?d T cells. Nat Commun. 2022 01 11; 13(1):231. PMID: 35017553; PMCID: PMC8752682.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  2. Sun W, Ma X, Wang H, Du Y, Chen J, Hu H, Gao R, He R, Peng Q, Cui Z, Zhang H, Wang J, Jia X, Martin BN, Zhang CJ, Li X, Wang C. MYO1F regulates antifungal immunity by regulating acetylation of microtubules. Proc Natl Acad Sci U S A. 2021 07 27; 118(30). PMID: 34301894.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  3. He R, Wu S, Gao R, Chen J, Peng Q, Hu H, Zhu L, Du Y, Sun W, Ma X, Zhang H, Cui Z, Wang H, Martin BN, Wang Y, Zhang CJ, Wang C. Identification of a Long Noncoding RNA TRAF3IP2-AS1 as Key Regulator of IL-17 Signaling through the SRSF10-IRF1-Act1 Axis in Autoimmune Diseases. J Immunol. 2021 05 15; 206(10):2353-2365. PMID: 33941656.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  4. Zhang H, Cui Z, Cheng D, Du Y, Guo X, Gao R, Chen J, Sun W, He R, Ma X, Peng Q, Martin BN, Yan W, Rong Y, Wang C. RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis. Autophagy. 2021 10; 17(10):3030-3047. PMID: 33280498; PMCID: PMC8525924.
    Citations: 7     Fields:    Translation:AnimalsCells
  5. Chen J, He R, Sun W, Gao R, Peng Q, Zhu L, Du Y, Ma X, Guo X, Zhang H, Tan C, Wang J, Zhang W, Weng X, Man J, Bauer H, Wang QK, Martin BN, Zhang CJ, Li X, Wang C. TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response. Nat Commun. 2020 04 20; 11(1):1913. PMID: 32312989.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  6. Zhang CJ, Wang C, Jiang M, Gu C, Xiao J, Chen X, Martin BN, Tang F, Yamamoto E, Xian Y, Wang H, Li F, Sartor RB, Smith H, Husni ME, Shi FD, Gao J, Carman J, Dongre A, McKarns SC, Coppieters K, Jørgensen TN, Leonard WJ, Li X. Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nat Commun. 2018 07 16; 9(1):2745. PMID: 30013031.
    Citations: 14     Fields:    Translation:AnimalsCells
  7. Wang C, Zhang CJ, Martin BN, Bulek K, Kang Z, Zhao J, Bian G, Carman JA, Gao J, Dongre A, Xue H, Miller SD, Qian Y, Hambardzumyan D, Hamilton T, Ransohoff RM, Li X. IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression. Nat Commun. 2017 05 31; 8:15508. PMID: 28561022; PMCID: PMC5460031.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  8. Liu C, Zhu L, Fukuda K, Ouyang S, Chen X, Wang C, Zhang CJ, Martin B, Gu C, Qin L, Rachakonda S, Aronica M, Qin J, Li X. The flavonoid cyanidin blocks binding of the cytokine interleukin-17A to the IL-17RA subunit to alleviate inflammation in vivo. Sci Signal. 2017 02 21; 10(467). PMID: 28223414.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  9. Zhou H, Yu M, Zhao J, Martin BN, Roychowdhury S, McMullen MR, Wang E, Fox PL, Yamasaki S, Nagy LE, Li X. IRAKM-Mincle axis links cell death to inflammation: Pathophysiological implications for chronic alcoholic liver disease. Hepatology. 2016 12; 64(6):1978-1993. PMID: 27628766.
    Citations: 30     Fields:    Translation:Animals
  10. Martin BN, Wang C, Zhang CJ, Kang Z, Gulen MF, Zepp JA, Zhao J, Bian G, Do JS, Min B, Pavicic PG, El-Sanadi C, Fox PL, Akitsu A, Iwakura Y, Sarkar A, Wewers MD, Kaiser WJ, Mocarski ES, Rothenberg ME, Hise AG, Dubyak GR, Ransohoff RM, Li X. T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis. Nat Immunol. 2016 May; 17(5):583-92. PMID: 26998763.
    Citations: 68     Fields:    Translation:AnimalsCells
  11. Wu L, Chen X, Zhao J, Martin B, Zepp JA, Ko JS, Gu C, Cai G, Ouyang W, Sen G, Stark GR, Su B, Vines CM, Tournier C, Hamilton TA, Vidimos A, Gastman B, Liu C, Li X. A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis. J Exp Med. 2015 Sep 21; 212(10):1571-87. PMID: 26347473.
    Citations: 78     Fields:    Translation:HumansAnimalsCells
  12. Zhao J, Bulek K, Gulen MF, Zepp JA, Karagkounis G, Martin BN, Zhou H, Yu M, Liu X, Huang E, Fox PL, Kalady MF, Markowitz SD, Li X. Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice. Gastroenterology. 2015 Dec; 149(7):1860-1871.e8. PMID: 26344057; PMCID: PMC5308447.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  13. Antonopoulos C, Russo HM, El Sanadi C, Martin BN, Li X, Kaiser WJ, Mocarski ES, Dubyak GR. Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling. J Biol Chem. 2015 Aug 14; 290(33):20167-84. PMID: 26100631.
    Citations: 86     Fields:    Translation:AnimalsCells
  14. Wu L, Zepp JA, Qian W, Martin BN, Ouyang W, Yin W, Bunting KD, Aronica M, Erzurum S, Li X. A novel IL-25 signaling pathway through STAT5. J Immunol. 2015 May 01; 194(9):4528-34. PMID: 25821217; PMCID: PMC4402248.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  15. Martin BN, Wang C, Willette-Brown J, Herjan T, Gulen MF, Zhou H, Bulek K, Franchi L, Sato T, Alnemri ES, Narla G, Zhong XP, Thomas J, Klinman D, Fitzgerald KA, Karin M, Nuñez G, Dubyak G, Hu Y, Li X. IKKa negatively regulates ASC-dependent inflammasome activation. Nat Commun. 2014 Sep 30; 5:4977. PMID: 25266676.
    Citations: 52     Fields:    Translation:AnimalsCells
  16. Wang C, Wu L, Bulek K, Martin BN, Zepp JA, Kang Z, Liu C, Herjan T, Misra S, Carman JA, Gao J, Dongre A, Han S, Bunting KD, Ko JS, Xiao H, Kuchroo VK, Ouyang W, Li X. The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90. Nat Immunol. 2013 Jan; 14(1):72-81. PMID: 23202271.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.