Harvard Catalyst Profiles

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Chunyan Ren, Ph.D.


Mount Sinai School of Medicine, New York, NYPhD08/2015Biophysics & Systems Pharmacology
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, ChinaMS08/2008Biomedical Science
Nankai University, Tianjin, ChinaBS08/2005Biological Science

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sher F, Hossain M, Seruggia D, Schoonenberg VAC, Yao Q, Cifani P, Dassama LMK, Cole MA, Ren C, Vinjamur DS, Macias-Trevino C, Luk K, McGuckin C, Schupp PG, Canver MC, Kurita R, Nakamura Y, Fujiwara Y, Wolfe SA, Pinello L, Maeda T, Kentsis A, Orkin SH, Bauer DE. Rational targeting of a NuRD subcomplex guided by comprehensive in situ mutagenesis. Nat Genet. 2019 07; 51(7):1149-1159. PMID: 31253978.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  2. Wu Y, Zeng J, Roscoe BP, Liu P, Yao Q, Lazzarotto CR, Clement K, Cole MA, Luk K, Baricordi C, Shen AH, Ren C, Esrick EB, Manis JP, Dorfman DM, Williams DA, Biffi A, Brugnara C, Biasco L, Brendel C, Pinello L, Tsai SQ, Wolfe SA, Bauer DE. Highly efficient therapeutic gene editing of human hematopoietic stem cells. Nat Med. 2019 05; 25(5):776-783. PMID: 30911135.
    Citations: 91     Fields:    Translation:HumansCells
  3. Zhang F, Zhao S, Ren C, Zhu Y, Zhou H, Lai Y, Zhou F, Jia Y, Zheng K, Huang Z. CRISPRminer is a knowledge base for exploring CRISPR-Cas systems in microbe and phage interactions. Commun Biol. 2018; 1:180. PMID: 30393777.
    Citations: 12     
  4. Ren C, Zhang G, Han F, Fu S, Cao Y, Zhang F, Zhang Q, Meslamani J, Xu Y, Ji D, Cao L, Zhou Q, Cheung KL, Sharma R, Babault N, Yi Z, Zhang W, Walsh MJ, Zeng L, Zhou MM. Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth. Proc Natl Acad Sci U S A. 2018 07 31; 115(31):7949-7954. PMID: 30012592.
    Citations: 11     Fields:    Translation:HumansCells
  5. Konuma T, Yu D, Zhao C, Ju Y, Sharma R, Ren C, Zhang Q, Zhou MM, Zeng L. Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4. Sci Rep. 2017 11 24; 7(1):16272. PMID: 29176719.
    Citations: 6     Fields:    Translation:HumansCells
  6. Cheung KL, Zhang F, Jaganathan A, Sharma R, Zhang Q, Konuma T, Shen T, Lee JY, Ren C, Chen CH, Lu G, Olson MR, Zhang W, Kaplan MH, Littman DR, Walsh MJ, Xiong H, Zeng L, Zhou MM. Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation. Mol Cell. 2017 Mar 16; 65(6):1068-1080.e5. PMID: 28262505.
    Citations: 34     Fields:    Translation:AnimalsCells
  7. Zhang F, Ren C, Zhao H, Yang L, Su F, Zhou MM, Han J, Sobie EA, Walsh MJ. Identification of novel prognostic indicators for triple-negative breast cancer patients through integrative analysis of cancer genomics data and protein interactome data. Oncotarget. 2016 Nov 01; 7(44):71620-71634. PMID: 27690302.
    Citations: 11     Fields:    Translation:Humans
  8. Zhang F, Ren C, Lau KK, Zheng Z, Lu G, Yi Z, Zhao Y, Su F, Zhang S, Zhang B, Sobie EA, Zhang W, Walsh MJ. A network medicine approach to build a comprehensive atlas for the prognosis of human cancer. Brief Bioinform. 2016 11; 17(6):1044-1059. PMID: 27559151.
    Citations: 18     Fields:    Translation:HumansCells
  9. Ren C, Zeng L, Zhou MM. Preparation, Biochemical Analysis, and Structure Determination of the Bromodomain, an Acetyl-Lysine Binding Domain. Methods Enzymol. 2016; 573:321-43. PMID: 27372760.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  10. Ren C, Smith SG, Yap K, Li S, Li J, Mezei M, Rodriguez Y, Vincek A, Aguilo F, Walsh MJ, Zhou MM. Structure-Guided Discovery of Selective Antagonists for the Chromodomain of Polycomb Repressive Protein CBX7. ACS Med Chem Lett. 2016 Jun 09; 7(6):601-5. PMID: 27326334.
    Citations: 15     
  11. Wu H, Ren C, Yang F, Qin Y, Zhang Y, Liu J. Extraction and identification of collagen-derived peptides with hematopoietic activity from Colla Corii Asini. J Ethnopharmacol. 2016 Apr 22; 182:129-36. PMID: 26911525.
    Citations: 12     Fields:    Translation:AnimalsCells
  12. Ren C, Morohashi K, Plotnikov AN, Jakoncic J, Smith SG, Li J, Zeng L, Rodriguez Y, Stojanoff V, Walsh M, Zhou MM. Small-molecule modulators of methyl-lysine binding for the CBX7 chromodomain. Chem Biol. 2015 Feb 19; 22(2):161-8. PMID: 25660273.
    Citations: 33     Fields:    Translation:HumansCells
  13. Jiang K, Ren C, Nair VD. MicroRNA-137 represses Klf4 and Tbx3 during differentiation of mouse embryonic stem cells. Stem Cell Res. 2013 Nov; 11(3):1299-313. PMID: 24084696.
    Citations: 18     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.