Harvard Catalyst Profiles

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Vanessa Sue Wacleche, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Smith K, Green MD, Wacleche VS. Young researchers series #4. Trends Cell Biol. 2022 08; 32(8):637-640. PMID: 35641371.
    Citations:    Fields:    Translation:Humans
  2. Wacleche VS, Wang R, Rao DA. Identification of T Peripheral Helper (Tph) Cells. Methods Mol Biol. 2022; 2380:59-76. PMID: 34802122.
    Citations: 2     Fields:    Translation:HumansCells
  3. Cattin A, Wacleche VS, Fonseca Do Rosario N, Marchand LR, Dias J, Gosselin A, Cohen EA, Estaquier J, Chomont N, Routy JP, Ancuta P. RALDH Activity Induced by Bacterial/Fungal Pathogens in CD16+ Monocyte-Derived Dendritic Cells Boosts HIV Infection and Outgrowth in CD4+ T Cells. J Immunol. 2021 06 01; 206(11):2638-2651. PMID: 34031148.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  4. Zhang Y, Planas D, Raymond Marchand L, Massanella M, Chen H, Wacleche VS, Gosselin A, Goulet JP, Filion M, Routy JP, Chomont N, Ancuta P. Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid. Front Microbiol. 2020; 11:902. PMID: 32499767; PMCID: PMC7243435.
    Citations: 6     
  5. Bocharnikov AV, Keegan J, Wacleche VS, Cao Y, Fonseka CY, Wang G, Muise ES, Zhang KX, Arazi A, Keras G, Li ZJ, Qu Y, Gurish MF, Petri M, Buyon JP, Putterman C, Wofsy D, James JA, Guthridge JM, Diamond B, Anolik JH, Mackey MF, Alves SE, Nigrovic PA, Costenbader KH, Brenner MB, Lederer JA, Rao DA. PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21. JCI Insight. 2019 10 17; 4(20). PMID: 31536480; PMCID: PMC6824311.
    Citations: 51     Fields:    Translation:HumansCells
  6. Wacleche VS, Cattin A, Goulet JP, Gauchat D, Gosselin A, Cleret-Buhot A, Zhang Y, Tremblay CL, Routy JP, Ancuta P. CD16+ monocytes give rise to CD103+RALDH2+TCF4+ dendritic cells with unique transcriptional and immunological features. Blood Adv. 2018 11 13; 2(21):2862-2878. PMID: 30381402; PMCID: PMC6234376.
    Citations: 7     Fields:    Translation:HumansCells
  7. Wacleche VS, Tremblay CL, Routy JP, Ancuta P. The Biology of Monocytes and Dendritic Cells: Contribution to HIV Pathogenesis. Viruses. 2018 02 06; 10(2). PMID: 29415518.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  8. Wacleche VS, Landay A, Routy JP, Ancuta P. The Th17 Lineage: From Barrier Surfaces Homeostasis to Autoimmunity, Cancer, and HIV-1 Pathogenesis. Viruses. 2017 10 19; 9(10). PMID: 29048384.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  9. Gosselin A, Wiche Salinas TR, Planas D, Wacleche VS, Zhang Y, Fromentin R, Chomont N, Cohen ÉA, Shacklett B, Mehraj V, Ghali MP, Routy JP, Ancuta P. HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy. AIDS. 2017 01 02; 31(1):35-48. PMID: 27835617; PMCID: PMC5131694.
    Citations: 70     Fields:    Translation:HumansCells
  10. Wacleche VS, Goulet JP, Gosselin A, Monteiro P, Soudeyns H, Fromentin R, Jenabian MA, Vartanian S, Deeks SG, Chomont N, Routy JP, Ancuta P. New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy. Retrovirology. 2016 08 24; 13(1):59. PMID: 27553844.
    Citations: 47     Fields:    Translation:HumansCells
  11. Cleret-Buhot A, Zhang Y, Planas D, Goulet JP, Monteiro P, Gosselin A, Wacleche VS, Tremblay CL, Jenabian MA, Routy JP, El-Far M, Chomont N, Haddad EK, Sekaly RP, Ancuta P. Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach. Retrovirology. 2015 Dec 10; 12:102. PMID: 26654242.
    Citations: 33     Fields:    Translation:HumansCells
  12. DaFonseca S, Niessl J, Pouvreau S, Wacleche VS, Gosselin A, Cleret-Buhot A, Bernard N, Tremblay C, Jenabian MA, Routy JP, Ancuta P. Impaired Th17 polarization of phenotypically naive CD4(+) T-cells during chronic HIV-1 infection and potential restoration with early ART. Retrovirology. 2015 Apr 30; 12:38. PMID: 25924895.
    Citations: 16     Fields:    Translation:HumansCells
  13. Bernier A, Cleret-Buhot A, Zhang Y, Goulet JP, Monteiro P, Gosselin A, DaFonseca S, Wacleche VS, Jenabian MA, Routy JP, Tremblay C, Ancuta P. Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies peroxisome proliferator-activated receptor gamma as an intrinsic negative regulator of viral replication. Retrovirology. 2013 Dec 21; 10:160. PMID: 24359430.
    Citations: 27     Fields:    Translation:HumansCells
  14. Wacleche VS, Chomont N, Gosselin A, Monteiro P, Goupil M, Kared H, Tremblay C, Bernard N, Boulassel MR, Routy JP, Ancuta P. The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin ß7 but not CCR6 and regulated by retinoic acid. PLoS One. 2012; 7(3):e32964. PMID: 22470433.
    Citations: 12     Fields:    Translation:HumansCells
  15. Monteiro P, Gosselin A, Wacleche VS, El-Far M, Said EA, Kared H, Grandvaux N, Boulassel MR, Routy JP, Ancuta P. Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin ß7. J Immunol. 2011 Apr 15; 186(8):4618-30. PMID: 21398606.
    Citations: 80     Fields:    Translation:HumansCells
  16. Gosselin A, Monteiro P, Chomont N, Diaz-Griffero F, Said EA, Fonseca S, Wacleche V, El-Far M, Boulassel MR, Routy JP, Sekaly RP, Ancuta P. Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection. J Immunol. 2010 Feb 01; 184(3):1604-16. PMID: 20042588; PMCID: PMC4321756.
    Citations: 168     Fields:    Translation:Cells
  17. Ancuta P, Liu KY, Misra V, Wacleche VS, Gosselin A, Zhou X, Gabuzda D. Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets. BMC Genomics. 2009 Aug 27; 10:403. PMID: 19712453.
    Citations: 110     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.