Harvard Catalyst Profiles

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Vanessa Sue Wacleche, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Wacleche VS, Cattin A, Goulet JP, Gauchat D, Gosselin A, Cleret-Buhot A, Zhang Y, Tremblay CL, Routy JP, Ancuta P. CD16+ monocytes give rise to CD103+RALDH2+TCF4+ dendritic cells with unique transcriptional and immunological features. Blood Adv. 2018 11 13; 2(21):2862-2878. PMID: 30381402.
    Citations:    
  2. Wacleche VS, Tremblay CL, Routy JP, Ancuta P. The Biology of Monocytes and Dendritic Cells: Contribution to HIV Pathogenesis. Viruses. 2018 02 06; 10(2). PMID: 29415518.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  3. Wacleche VS, Landay A, Routy JP, Ancuta P. The Th17 Lineage: From Barrier Surfaces Homeostasis to Autoimmunity, Cancer, and HIV-1 Pathogenesis. Viruses. 2017 10 19; 9(10). PMID: 29048384.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  4. Gosselin A, Wiche Salinas TR, Planas D, Wacleche VS, Zhang Y, Fromentin R, Chomont N, Cohen ÉA, Shacklett B, Mehraj V, Ghali MP, Routy JP, Ancuta P. HIV persists in CCR6+CD4+ T cells from colon and blood during antiretroviral therapy. AIDS. 2017 01 02; 31(1):35-48. PMID: 27835617.
    Citations: 12     Fields:    Translation:HumansCells
  5. Wacleche VS, Goulet JP, Gosselin A, Monteiro P, Soudeyns H, Fromentin R, Jenabian MA, Vartanian S, Deeks SG, Chomont N, Routy JP, Ancuta P. New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy. Retrovirology. 2016 08 24; 13(1):59. PMID: 27553844.
    Citations: 11     Fields:    Translation:HumansCells
  6. Cleret-Buhot A, Zhang Y, Planas D, Goulet JP, Monteiro P, Gosselin A, Wacleche VS, Tremblay CL, Jenabian MA, Routy JP, El-Far M, Chomont N, Haddad EK, Sekaly RP, Ancuta P. Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach. Retrovirology. 2015 Dec 10; 12:102. PMID: 26654242.
    Citations: 14     Fields:    Translation:HumansCells
  7. DaFonseca S, Niessl J, Pouvreau S, Wacleche VS, Gosselin A, Cleret-Buhot A, Bernard N, Tremblay C, Jenabian MA, Routy JP, Ancuta P. Impaired Th17 polarization of phenotypically naive CD4(+) T-cells during chronic HIV-1 infection and potential restoration with early ART. Retrovirology. 2015 Apr 30; 12:38. PMID: 25924895.
    Citations: 10     Fields:    Translation:HumansCells
  8. Bernier A, Cleret-Buhot A, Zhang Y, Goulet JP, Monteiro P, Gosselin A, DaFonseca S, Wacleche VS, Jenabian MA, Routy JP, Tremblay C, Ancuta P. Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies peroxisome proliferator-activated receptor gamma as an intrinsic negative regulator of viral replication. Retrovirology. 2013 Dec 21; 10:160. PMID: 24359430.
    Citations: 18     Fields:    Translation:HumansCells
  9. Wacleche VS, Chomont N, Gosselin A, Monteiro P, Goupil M, Kared H, Tremblay C, Bernard N, Boulassel MR, Routy JP, Ancuta P. The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin ß7 but not CCR6 and regulated by retinoic acid. PLoS One. 2012; 7(3):e32964. PMID: 22470433.
    Citations: 11     Fields:    Translation:HumansCells
  10. Monteiro P, Gosselin A, Wacleche VS, El-Far M, Said EA, Kared H, Grandvaux N, Boulassel MR, Routy JP, Ancuta P. Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin ß7. J Immunol. 2011 Apr 15; 186(8):4618-30. PMID: 21398606.
    Citations: 51     Fields:    Translation:HumansCells
  11. Gosselin A, Monteiro P, Chomont N, Diaz-Griffero F, Said EA, Fonseca S, Wacleche V, El-Far M, Boulassel MR, Routy JP, Sekaly RP, Ancuta P. Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection. J Immunol. 2010 Feb 01; 184(3):1604-16. PMID: 20042588.
    Citations: 96     Fields:    Translation:Cells
  12. Ancuta P, Liu KY, Misra V, Wacleche VS, Gosselin A, Zhou X, Gabuzda D. Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets. BMC Genomics. 2009 Aug 27; 10:403. PMID: 19712453.
    Citations: 75     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.