Manish Satish Hudlikar, Ph.D.
Research Fellow in Medicine (EXT)
Massachusetts General Hospital
149, 13th St.
55 Fruit St
Boston MA 02114
|The University of Georgia, Athens, GA||Ph.D.||12/2017||Chemistry|
|The University of Pune, India||M.Sc.||6/2010||Biochemistry|
|The University of Pune, India||B.Sc.||6/2008||Chemistry|
Innovative Technology Award
Visiting Research Scholar
Best Research Poster Award
2005 - 2008
KVPY Fellowship award
Being a chemical biologist with research experience in the multidisciplinary fields such as synthetic organic, analytical, polymer, bioconjugation chemistry, and cell/ molecular biology. I have applied this knowledge towards the development of targeted drug-delivery devices using nanoparticles and antibody-drug conjugates (ADCs) to improve the therapeutic index of many anticancer agents through structure-activity relationship (SAR) studies. I am highly motivated, productive and independent researcher with critical thinking, complex problem-solving abilities. I have been proficiently working in a team environment with an ability to work on multiple projects leading to increased productivity. With more than 7 years of experience in chemical biology, I have acquired expertise in drug discovery, site-specific conjugations for the preparation of homogeneous ADCs, multistep organic synthesis, total synthesis, bio-analytical techniques, and biological assays.
In addition to above assets, I have been efficiently managing lab waste as per EPA regulations and bulk order of common and special chemicals leading to cost reductions. I have added significant value in academic research by writing/reviewing grants/articles that have fostered industry collaborations to effectively translate therapeutic agents into the clinic. Recently, I have started my new adventure as a research fellow at MGH/Harvard Medical School with special focus on designing small molecules that can selectively target epigenetic gene regulatory complexes against multiple myeloma and acute myeloid leukemia.
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