Harvard Catalyst Profiles

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Charles Nicholas Serhan, Ph.D.

Co-Author

This page shows the publications co-authored by Charles Serhan and Bruce Levy.
Connection Strength

10.001
  1. Levy BD, Abdulnour RE, Tavares A, Brüggemann TR, Norris PC, Bai Y, Ai X, Serhan CN. Cysteinyl maresins regulate the prophlogistic lung actions of cysteinyl leukotrienes. J Allergy Clin Immunol. 2020 01; 145(1):335-344.
    View in: PubMed
    Score: 0.946
  2. Serhan CN, Levy BD. Resolvins in inflammation: emergence of the pro-resolving superfamily of mediators. J Clin Invest. 2018 07 02; 128(7):2657-2669.
    View in: PubMed
    Score: 0.858
  3. Serhan CN, Chiang N, Dalli J, Levy BD. Lipid mediators in the resolution of inflammation. Cold Spring Harb Perspect Biol. 2014 Oct 30; 7(2):a016311.
    View in: PubMed
    Score: 0.671
  4. Levy BD, Serhan CN. Resolution of acute inflammation in the lung. Annu Rev Physiol. 2014; 76:467-92.
    View in: PubMed
    Score: 0.630
  5. Levy BD, Vachier I, Serhan CN. Resolution of inflammation in asthma. Clin Chest Med. 2012 Sep; 33(3):559-70.
    View in: PubMed
    Score: 0.574
  6. Levy BD, Zhang QY, Bonnans C, Primo V, Reilly JJ, Perkins DL, Liang Y, Amin Arnaout M, Nikolic B, Serhan CN. The endogenous pro-resolving mediators lipoxin A4 and resolvin E1 preserve organ function in allograft rejection. Prostaglandins Leukot Essent Fatty Acids. 2011 Jan-Feb; 84(1-2):43-50.
    View in: PubMed
    Score: 0.505
  7. Levy BD, Kohli P, Gotlinger K, Haworth O, Hong S, Kazani S, Israel E, Haley KJ, Serhan CN. Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness. J Immunol. 2007 Jan 01; 178(1):496-502.
    View in: PubMed
    Score: 0.390
  8. Levy BD, Hickey L, Morris AJ, Larvie M, Keledjian R, Petasis NA, Bannenberg G, Serhan CN. Novel polyisoprenyl phosphates block phospholipase D and human neutrophil activation in vitro and murine peritoneal inflammation in vivo. Br J Pharmacol. 2005 Oct; 146(3):344-51.
    View in: PubMed
    Score: 0.358
  9. Serhan CN, Levy B. Success of prostaglandin E2 in structure-function is a challenge for structure-based therapeutics. Proc Natl Acad Sci U S A. 2003 Jul 22; 100(15):8609-11.
    View in: PubMed
    Score: 0.307
  10. Levy BD, Serhan CN. Exploring new approaches to the treatment of asthma: potential roles for lipoxins and aspirin-triggered lipid mediators. Drugs Today (Barc). 2003 May; 39(5):373-84.
    View in: PubMed
    Score: 0.302
  11. Serhan CN, Levy B. Novel pathways and endogenous mediators in anti-inflammation and resolution. Chem Immunol Allergy. 2003; 83:115-45.
    View in: PubMed
    Score: 0.296
  12. Levy BD, De Sanctis GT, Devchand PR, Kim E, Ackerman K, Schmidt B, Szczeklik W, Drazen JM, Serhan CN. Lipoxins and aspirin-triggered lipoxins in airway responses. Adv Exp Med Biol. 2003; 525:19-23.
    View in: PubMed
    Score: 0.296
  13. Levy BD, De Sanctis GT, Devchand PR, Kim E, Ackerman K, Schmidt BA, Szczeklik W, Drazen JM, Serhan CN. Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4). Nat Med. 2002 Sep; 8(9):1018-23.
    View in: PubMed
    Score: 0.288
  14. Levy BD, Serhan CN. Polyisoprenyl phosphates: natural antiinflammatory lipid signals. Cell Mol Life Sci. 2002 May; 59(5):729-41.
    View in: PubMed
    Score: 0.282
  15. Levy BD, Clish CB, Schmidt B, Gronert K, Serhan CN. Lipid mediator class switching during acute inflammation: signals in resolution. Nat Immunol. 2001 Jul; 2(7):612-9.
    View in: PubMed
    Score: 0.266
  16. Levy BD, Serhan CN. Polyisoprenyl phosphate signaling: topography in human neutrophils. Biochem Biophys Res Commun. 2000 Sep 07; 275(3):739-45.
    View in: PubMed
    Score: 0.252
  17. Levy BD, Serhan CN. A novel polyisoprenyl phosphate signaling cascade in human neutrophils. Ann N Y Acad Sci. 2000 Apr; 905:69-80.
    View in: PubMed
    Score: 0.244
  18. Levy BD, Fokin VV, Clark JM, Wakelam MJ, Petasis NA, Serhan CN. Polyisoprenyl phosphate (PIPP) signaling regulates phospholipase D activity: a 'stop' signaling switch for aspirin-triggered lipoxin A4. FASEB J. 1999 May; 13(8):903-11.
    View in: PubMed
    Score: 0.229
  19. Sham HP, Walker KH, Abdulnour RE, Krishnamoorthy N, Douda DN, Norris PC, Barkas I, Benito-Figueroa S, Colby JK, Serhan CN, Levy BD. 15-epi-Lipoxin A4, Resolvin D2, and Resolvin D3 Induce NF-?B Regulators in Bacterial Pneumonia. J Immunol. 2018 04 15; 200(8):2757-2766.
    View in: PubMed
    Score: 0.212
  20. Levy BD, Petasis NA, Serhan CN. Polyisoprenyl phosphates in intracellular signalling. Nature. 1997 Oct 30; 389(6654):985-90.
    View in: PubMed
    Score: 0.207
  21. Levy BD, Drazen JM, Serhan CN. Agonist-induced lipoxin A4 generation in vitro and in aspirin-sensitive asthmatics: detection by a novel lipoxin A4-ELISA. Adv Exp Med Biol. 1997; 400B:611-5.
    View in: PubMed
    Score: 0.195
  22. Colby JK, Abdulnour RE, Sham HP, Dalli J, Colas RA, Winkler JW, Hellmann J, Wong B, Cui Y, El-Chemaly S, Petasis NA, Spite M, Serhan CN, Levy BD. Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia. Am J Pathol. 2016 07; 186(7):1801-1813.
    View in: PubMed
    Score: 0.187
  23. Krishnamoorthy N, Burkett PR, Dalli J, Abdulnour RE, Colas R, Ramon S, Phipps RP, Petasis NA, Kuchroo VK, Serhan CN, Levy BD. Cutting edge: maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation. J Immunol. 2015 Feb 01; 194(3):863-7.
    View in: PubMed
    Score: 0.170
  24. Serhan CN, Fiore S, Levy BD. Cell-cell interactions in lipoxin generation and characterization of lipoxin A4 receptors. Ann N Y Acad Sci. 1994 Nov 15; 744:166-80.
    View in: PubMed
    Score: 0.168
  25. Abdulnour RE, Dalli J, Colby JK, Krishnamoorthy N, Timmons JY, Tan SH, Colas RA, Petasis NA, Serhan CN, Levy BD. Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective. Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46):16526-31.
    View in: PubMed
    Score: 0.168
  26. Levy BD, Bertram S, Tai HH, Israel E, Fischer A, Drazen JM, Serhan CN. Agonist-induced lipoxin A4 generation: detection by a novel lipoxin A4-ELISA. Lipids. 1993 Dec; 28(12):1047-53.
    View in: PubMed
    Score: 0.157
  27. Levy BD, Romano M, Chapman HA, Reilly JJ, Drazen J, Serhan CN. Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. J Clin Invest. 1993 Sep; 92(3):1572-9.
    View in: PubMed
    Score: 0.155
  28. Rogerio AP, Haworth O, Croze R, Oh SF, Uddin M, Carlo T, Pfeffer MA, Priluck R, Serhan CN, Levy BD. Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responses. J Immunol. 2012 Aug 15; 189(4):1983-91.
    View in: PubMed
    Score: 0.143
  29. Haworth O, Cernadas M, Yang R, Serhan CN, Levy BD. Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A4 to promote the resolution of allergic airway inflammation. Nat Immunol. 2008 Aug; 9(8):873-9.
    View in: PubMed
    Score: 0.108
  30. Levy BD, Lukacs NW, Berlin AA, Schmidt B, Guilford WJ, Serhan CN, Parkinson JF. Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism. FASEB J. 2007 Dec; 21(14):3877-84.
    View in: PubMed
    Score: 0.101
  31. Gronert K, Kantarci A, Levy BD, Clish CB, Odparlik S, Hasturk H, Badwey JA, Colgan SP, Van Dyke TE, Serhan CN. A molecular defect in intracellular lipid signaling in human neutrophils in localized aggressive periodontal tissue damage. J Immunol. 2004 Feb 01; 172(3):1856-61.
    View in: PubMed
    Score: 0.080
  32. Clish CB, Levy BD, Chiang N, Tai HH, Serhan CN. Oxidoreductases in lipoxin A4 metabolic inactivation: a novel role for 15-onoprostaglandin 13-reductase/leukotriene B4 12-hydroxydehydrogenase in inflammation. J Biol Chem. 2000 Aug 18; 275(33):25372-80.
    View in: PubMed
    Score: 0.063
  33. Serhan CN, Levy BD, Clish CB, Gronert K, Chiang N. Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity. Ernst Schering Res Found Workshop. 2000; (31):143-85.
    View in: PubMed
    Score: 0.060
  34. Dalli J, Colas RA, Quintana C, Barragan-Bradford D, Hurwitz S, Levy BD, Choi AM, Serhan CN, Baron RM. Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes. Crit Care Med. 2017 Jan; 45(1):58-68.
    View in: PubMed
    Score: 0.049
  35. Ramaswami R, Serhan CN, Levy BD, Makrides M. Fish Oil Supplementation in Pregnancy. N Engl J Med. 2016 12 29; 375(26):2599-2601.
    View in: PubMed
    Score: 0.049
  36. Hasturk H, Kantarci A, Ohira T, Arita M, Ebrahimi N, Chiang N, Petasis NA, Levy BD, Serhan CN, Van Dyke TE. RvE1 protects from local inflammation and osteoclast- mediated bone destruction in periodontitis. FASEB J. 2006 Feb; 20(2):401-3.
    View in: PubMed
    Score: 0.023
  37. Sanak M, Levy BD, Clish CB, Chiang N, Gronert K, Mastalerz L, Serhan CN, Szczeklik A. Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics. Eur Respir J. 2000 Jul; 16(1):44-9.
    View in: PubMed
    Score: 0.016
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.